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NRVFVVGVGMTKFEKPGRMENWDYPDMARESGTKALEDAGIAYSEIQQGYVGYCSGDSTSGQRALYELGM TGIPIVNVNNNCSTGSTALYLAAQSIRGGLADCVLALGFEKMQPGSLGGGAQDRESPLGRHVKALSEIDE FAFPVAPWMFGAAGREHMKKYGTTAEHFAKIGFKNHKHSVNNPYAQFQDEYSLDDILAAKMISDPLTKLQ CSPTSDGSAAVVLASEDYVARHDLAGQAVEIVGQAMTTDFASTFDGSAANIIGHDMNVKAAQQVYSQSGL GPEDFQVIELHDCFSANELLLYEALGLCGPGEAPRLIDDNDTTYGGRWVVNPSGGLISKGHPLGATGLAQ CSELTWQLRGTADKRQVDGVTAALQHNIGLGGAAVVTAYQRAER*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2025 | - | - | 100% (395) | lipid-transfer protein |
| M. gilvum PYR-GCK | Mflv_2505 | - | 4e-51 | 33.85% (384) | thiolase |
| M. gilvum PYR-GCK | Mflv_4527 | - | 6e-51 | 33.67% (401) | lipid-transfer protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2813c | ltp1 | 0.0 | 89.85% (394) | lipid-transfer protein |
| M. tuberculosis H37Rv | Rv2790c | ltp1 | 0.0 | 89.85% (394) | lipid-transfer protein |
| M. leprae Br4923 | MLBr_01158 | fadA4 | 7e-12 | 23.32% (386) | acetyl-CoA acetyltransferase |
| M. abscessus ATCC 19977 | MAB_2951c | - | 0.0 | 79.70% (399) | lipid-transfer protein |
| M. marinum M | MMAR_1918 | ltp1 | 0.0 | 82.99% (394) | lipid-transfer protein Ltp1 |
| M. avium 104 | MAV_3681 | - | 0.0 | 86.80% (394) | lipid-transfer protein |
| M. smegmatis MC2 155 | MSMEG_3844 | - | 3e-51 | 33.57% (414) | lipid-transfer protein |
| M. thermoresistible (build 8) | TH_2497 | - | 1e-54 | 36.73% (373) | PUTATIVE putative thiolase |
| M. ulcerans Agy99 | MUL_2143 | ltp1 | 0.0 | 82.49% (394) | lipid-transfer protein |
| M. vanbaalenii PYR-1 | Mvan_4694 | - | 0.0 | 90.15% (406) | lipid-transfer protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2025|M.gilvum_PYR-GCK ------MNRVFVVGVGMTKFEKPGR-----------MENWDYPDMARESG
Mvan_4694|M.vanbaalenii_PYR-1 ------MKRVFVVGVGMTKFEKPGGRAARGADHEPGREGWDYPDMARESG
Mb2813c|M.bovis_AF2122/97 MPNQGSSNKVYVIGVGMTKFEKPGR-----------REGWDYPDMARESG
Rv2790c|M.tuberculosis_H37Rv MPNQGSSNKVYVIGVGMTKFEKPGR-----------REGWDYPDMARESG
MAV_3681|M.avium_104 -----MSNKVYVVGVGMTKFEKPGR-----------REGWDYPGMARESG
MMAR_1918|M.marinum_M -MPNNGSNRVFVIGVGMTKFEKPGRRE-----------GWDYPDMARESG
MUL_2143|M.ulcerans_Agy99 -MPNNGSNRVFVIGVGMTKFEKPGRRE-----------GWDYPDMARESG
MAB_2951c|M.abscessus_ATCC_199 -MAN----RVYVVGVGMTKFEKPGRRLNDD------GSAWDYPDMARESG
MSMEG_3844|M.smegmatis_MC2_155 ---MSAPEPVYILGAGMHPWGKWG---------------RDFTEYGVVAA
TH_2497|M.thermoresistible__bu ------MTRVQIVGAGLSRFGRQPD--------------KTGRQLAVEAI
MLBr_01158|M.leprae_Br4923 -----MTTSVIVTGARTPIGKLMGS-----------LKDFSASDLGAITI
* : *. . :
Mflv_2025|M.gilvum_PYR-GCK TKALEDAGIAYSEIQQGYVGYCSGDS----TSGQRALYELGMTG-----I
Mvan_4694|M.vanbaalenii_PYR-1 TKALEDAGVAYTEIQQGYVGYCTGDS----TSGQRALYELGMTG-----I
Mb2813c|M.bovis_AF2122/97 TKALRDAGIDYREVEQGYVGYVYGES----TSGQRALYELGMTG-----I
Rv2790c|M.tuberculosis_H37Rv TKALRDAGIDYREVEQGYVGYVYGES----TSGQRALYELGMTG-----I
MAV_3681|M.avium_104 TNALADAGIDYREVQQGYVGYVAGDS----TSGQRALYELGMTG-----I
MMAR_1918|M.marinum_M TNALNDAGIEYREVEHAYVGYVYGES----TSGQRAVYELGMTG-----I
MUL_2143|M.ulcerans_Agy99 TNALNDAGIEYREVEHAYVGYVYGES----TSGQRAVYELGMTG-----I
MAB_2951c|M.abscessus_ATCC_199 TKALADAGIGYDLVEQAYVGYVYGES----TSGQRAVYELGMSG-----I
MSMEG_3844|M.smegmatis_MC2_155 RAALAEAGLDWRQIQLVAGADTIRNGYPGFVAGATFAQKLGWNG-----V
TH_2497|M.thermoresistible__bu HAALADAGIGWDDVQIAFGGSDSAG------LADTLVNEIGLTG-----I
MLBr_01158|M.leprae_Br4923 AAALKKANVAPSIVQYVIIGQVLTAG-----AGQMPARQAAVAAGIGWDV
** .*.: :: . . : . . :
Mflv_2025|M.gilvum_PYR-GCK PIVNVNNNCSTGSTALYLAAQSIRGGLADCVLALGFEKMQPGSLGGGAQD
Mvan_4694|M.vanbaalenii_PYR-1 PIANVNNNCSTGSTALYLAAQAIRGGLADCTLALGFEKMQPGSLGAGAED
Mb2813c|M.bovis_AF2122/97 PIVNVNNNCSTGSTALYLGAQAIRGGLADCVLALGFEKMQPGALGGGADD
Rv2790c|M.tuberculosis_H37Rv PIVNVNNNCSTGSTALYLGAQAIRGGLADCVLALGFEKMQPGALGGGADD
MAV_3681|M.avium_104 PIVNVNNNCSTGSTALFLAAQAIRGGLVDCAIALGFEKMQPGSLGGGAQD
MMAR_1918|M.marinum_M PVVNVNNNCSTGSTALFLAAQAIRGGLADCTVALGFEKMKPGSLSSSYDD
MUL_2143|M.ulcerans_Agy99 PVVNVNNNCSTGSTALFLAAQAIRGGLADCTVALGFEKMKPGSLSSSYDD
MAB_2951c|M.abscessus_ATCC_199 PVVNVNNNCSTGSTALYLAAQSIRGGLADCALALGFEKMNPGSLGAMYDD
MSMEG_3844|M.smegmatis_MC2_155 PVTSSYAACASGSQALQSARAQILAGFCDVALVVGADTTPKGFFAPVGGE
TH_2497|M.thermoresistible__bu PFTNVKNGCATGGSALVCAINAIRSGAADIALAVGFDKHPRGAFDPRPED
MLBr_01158|M.leprae_Br4923 PALTINKMCLSGLDAIALADQLIRAGEFDVVVAGGQESMTKAPHLLMD--
* . * :* *: . * .* * .:. * :. .
Mflv_2025|M.gilvum_PYR-GCK RESPLGRHVKALSEIDEFAFPVAPWMFGAAGREHMKKYGTTAEHFAKIGF
Mvan_4694|M.vanbaalenii_PYR-1 RESPLKRHILALNEIDAMQFPVAPWMFGAAGREHMKKYGTTAEHFAKIGY
Mb2813c|M.bovis_AF2122/97 RESPLGRHVKALAEIDEFGFPVAPWMFGAAGREHMKKYGTTAEHFAKIGY
Rv2790c|M.tuberculosis_H37Rv RESPLGRHVKALAEIDEFGFPVAPWMFGAAGREHMKKYGTTAEHFAKIGY
MAV_3681|M.avium_104 RESPMGRHVKAMAEIDEFAMPVAPWMFGAAGREHMRQYGSTAEHFAKIGY
MMAR_1918|M.marinum_M RTQPMDKHVKALAQIAEFAFPVAPWMFGAAGREHMQQYGSTAEHFAKIGF
MUL_2143|M.ulcerans_Agy99 RTQPMDKHVKALAQIAEFAFPVAPWMFGAAGREHMQQYGSTAEHFAKIGF
MAB_2951c|M.abscessus_ATCC_199 RAQPMEKHILALAEISEVLFPPASWMFGAAGREHMQQYGSTAEHFAKIGH
MSMEG_3844|M.smegmatis_MC2_155 RKNDPDWQRFHLIGATNT------VYFALLARRRMDLYGATLEDFAQVKV
TH_2497|M.thermoresistible__bu WGLPTGYGEAGLMVTT--------QFFGIKIARYMREHGISSRTLALVAE
MLBr_01158|M.leprae_Br4923 --SRSGYKYGDVTIVDHLAYDGLHDVFTNQPMGALTEQRNDVEKFTRQEQ
: * : . ::
Mflv_2025|M.gilvum_PYR-GCK KNHKH-SVNNPYAQFQDEYSLDDILAAKMISDPLTKLQCSPTS---DGSA
Mvan_4694|M.vanbaalenii_PYR-1 KNHKH-SVNNPYAQFQDEYSLEDILAAKMISDPLTKLQCSPTS---DGSA
Mb2813c|M.bovis_AF2122/97 KNHKH-SVNNPYAQFQDEYTLDDILASKMISDPLTKLQCSPTS---DGSA
Rv2790c|M.tuberculosis_H37Rv KNHKH-SVNNPYAQFQDEYTLDDILASKMISDPLTKLQCSPTS---DGSA
MAV_3681|M.avium_104 KNHKH-SVNNPFAQFQESYTLEDILAARMISDPLTKLQCSPTS---DGSG
MMAR_1918|M.marinum_M KNHKH-SVNNPFAQFQEAYTLDDILASRMIYEPLTKLQCSPTS---DGSG
MUL_2143|M.ulcerans_Agy99 KNHKH-SVNNPFAQFQEAYTLDDILASRMIYEPLTKLRCSPTS---DGSG
MAB_2951c|M.abscessus_ATCC_199 KNHKH-SVNNPYAQFQDEYTLDDILNSRMIYDPLTKLQCSPTS---DGSG
MSMEG_3844|M.smegmatis_MC2_155 KNARH-GLNNPNARYRKEASVEDVLASPVVSDPLRLLDICATS---DGAA
TH_2497|M.thermoresistible__bu KAYRN-GSLNPNAWRREPLSADEIANADMVNDPLTRYMFCSPG---EGGA
MLBr_01158|M.leprae_Br4923 DEFAARSHQKAAAAWKDGVFADEVVPVSIPQSKGDSLQFTEDEGIRANTS
. . :. * :. ::: : . . .
Mflv_2025|M.gilvum_PYR-GCK AVVLASEDYVARHD--LAGQAVEIVGQAMTTDFASTFDGSAANIIGHDMN
Mvan_4694|M.vanbaalenii_PYR-1 AVVLASEDYVARHD--LAGRAVEIVGQAMTTDFASTFDGSAANIIGHDMN
Mb2813c|M.bovis_AF2122/97 AVVLASEDYLANHN--LAGRAVEIVGQAMTTDFASTFDGSARNIIGYDMT
Rv2790c|M.tuberculosis_H37Rv AVVLASEDYLANHN--LAGRAVEIVGQAMTTDFASTFDGSARNIIGYDMT
MAV_3681|M.avium_104 AAILASEAFVDKHG--LAGQAVEIVGQAMTTDFASTFDGSAKNLIGYDMN
MMAR_1918|M.marinum_M AAILASESFVDSHG--LAGRAVEIVGQAMTTDFASTFDGSAKNLIGYDMN
MUL_2143|M.ulcerans_Agy99 AAILASESFVDSHG--LAGRAVEIVGQAMTTDFASTFDGSAKNLIGYDMN
MAB_2951c|M.abscessus_ATCC_199 AAILASEAFVDRHG--LASQAVEIVGQAMTTDFQNSFDGTCKAIIGYHMN
MSMEG_3844|M.smegmatis_MC2_155 ALVVASKSFVEKHLGSVEGVPSVRAISLQSPQYPQHLPELPDIATDSTAV
TH_2497|M.thermoresistible__bu AIVLASEKAAARLDSQPVTLVAAATRTRRFGSFEVFAPAIQGTGTPSSVS
MLBr_01158|M.leprae_Br4923 AESLAGLKPAFRCGGTITPGSASQISDGAATVVVMNKEKAQQLGLTWLVE
* :*.
Mflv_2025|M.gilvum_PYR-GCK VKAAQQ---------VYSQSGLGPEDFQVIELHDCFSANELLLYEALGLC
Mvan_4694|M.vanbaalenii_PYR-1 VKAAQQ---------VYDQSGLGPQDFQVIELHDCFSANELLLYEALGLC
Mb2813c|M.bovis_AF2122/97 VQAAQR---------VYQQSGLGPKDFGVIELHDCFSANELLLYEALGLC
Rv2790c|M.tuberculosis_H37Rv VQAAQR---------VYQQSGLGPKDFGVIELHDCFSANELLLYEALGLC
MAV_3681|M.avium_104 VQAAQQ---------VYDQSGLGPQDFQVIELHDCFSANELLLYEALGLC
MMAR_1918|M.marinum_M VQAAQR---------VYQQSGLGPEDFQVIELHDCFSANELLLYEALGLC
MUL_2143|M.ulcerans_Agy99 VQAARR---------VYQQSGLGPEDFQVIELHDCFSANELLLYEALGLC
MAB_2951c|M.abscessus_ATCC_199 VSAARQ---------VYDQSGLGAEDFQVIELHDCFSANEFLLYEALGLC
MSMEG_3844|M.smegmatis_MC2_155 VKAPERVFKDQILDAAYAEAGIGPEDLSLAEVYDLSTALELDWYEHLGLC
TH_2497|M.thermoresistible__bu ADAAQ---------AVFEAAGVGPEDMDVLQLQDTESGAEIMHMAECGFC
MLBr_01158|M.leprae_Br4923 IGAHGV--------VAGPDSTLQSQPANAIKKAVDREGISVEQLDVVEIN
* . : : .: : . .. :
Mflv_2025|M.gilvum_PYR-GCK GPGEAPRLIDDNDTTYGGRWVVNPSGGLISKGHPLGATGLAQCSELTWQL
Mvan_4694|M.vanbaalenii_PYR-1 GPGEAPALIDADDTTYGGRWVVNPSGGLISKGHPLGATGLAQCSELTWQL
Mb2813c|M.bovis_AF2122/97 GPGEAPELIDDNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQL
Rv2790c|M.tuberculosis_H37Rv GPGEAPELIDDNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQL
MAV_3681|M.avium_104 GPGEAPKLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQL
MMAR_1918|M.marinum_M GQGEAPKLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCCELTWQL
MUL_2143|M.ulcerans_Agy99 GQGEAPKLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCCELTWQL
MAB_2951c|M.abscessus_ATCC_199 GEGEAGKLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQL
MSMEG_3844|M.smegmatis_MC2_155 EKGEAEQLLRSGATTIGGRIPVNASGGLACFGEAIPAQAIAQVCELTWQL
TH_2497|M.thermoresistible__bu EHGEQEKLISAGETAIGGRMPVNTDGGCIANGEPIGASGLRQVYEIVTQL
MLBr_01158|M.leprae_Br4923 EAFAAVALASARELGIAP-ELVNVNGGAIAVGHPLGMSGARITLHVALEL
* . ** .** . *..: . .:. :*
Mflv_2025|M.gilvum_PYR-GCK RGTADKRQVDG-VTAALQHNIGLGGAAVVTAYQRAER-
Mvan_4694|M.vanbaalenii_PYR-1 RGTADKRQVDD-VSAALQHNIGLGGAAVVTAYQRAER-
Mb2813c|M.bovis_AF2122/97 RGTAEARQVDN-VTAALQHNIGLGGAAVVTAYQRAER-
Rv2790c|M.tuberculosis_H37Rv RGTAEARQVDN-VTAALQHNIGLGGAAVVTAYQRAER-
MAV_3681|M.avium_104 RGTADKRQVEN-VSAALQHNIGLGGAAVVTAYQRAER-
MMAR_1918|M.marinum_M RGTADRRQVDD-VTAALQHNIGLGGAAVVTAYQRAER-
MUL_2143|M.ulcerans_Agy99 RGTADRRQVDN-VTAALQHNIGLGGAAVVTAYQRAER-
MAB_2951c|M.abscessus_ATCC_199 RGAADKRQVDR-VDAALQHNIGLGGAAVITAYQRAER-
MSMEG_3844|M.smegmatis_MC2_155 KGQATGRQVEG-AKVGITANQGLFGHGSSVIVAR----
TH_2497|M.thermoresistible__bu RGRAGDRQVPNEPRFGFTHVYGAPGISACTVLATQETL
MLBr_01158|M.leprae_Br4923 ARRGSG--------YGVAALCGAGGQGDALILRAV---
. .. * * .