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SFVIAVPEALTMAASDLANIGSTINAANAAAALPTTGVVAAAADEVSAAVAALFGSYAQSYQAFGAQLSA FHAQFVQSLTNGARSYVVAEATSAAPLQDLLGVVNAPAQALLGRPLIGNGANGADGTGAPGGPGGLLLGN GGNGGSGAPGQPGGAGGDAGLIGNGGTGGKGGDGLVGSGAAGGVGGRGGWLLGNGGTGGAGGAAGATLVG GTGGVGGATGLIGSGGFGGAGGAAAGVGTTGGVGGSGGVGGVFGNGGFGGAGGLGAAGGVGGAASYFGTG GGGGVGGDGAPGGDGGAGPLLIGNGGVGGLGGAGAAGGNGGAGGMLLGDGGAGGQGGPAVAGVLGGMPGA GGNGGNANWFGSGGAGGQGGTGLAGTNGVNPGSIANPNTGANGTDNSGNGNQTGGNGGPGPAGGVGEAGG VGGQGGLGESLDGNDGTGGKGGAGGTAGTDGGAGGAGGAGGIGETDGSAGGVATGGEGGDGATGGVDGGV GGAGGKGGQGHNTGVGDAFGGDGGIGGDGNGALGAAGGNGGTGGAGGNGGRGGMLIGNGGAGGAGGTGGT GGGGAAGFAGGVGGAGGEGLTDGAGTAEGGTGGLGGLGGVGGTGGMGGSGGVGGNGGAAGSLIGLGGGGG AGGVGGTGGIGGIGGAGGNGGAGGAGTTTGGGATIGGGGGTGGVGGAGGTGGTGGAGGTTGGSGGAGGLI GWAGAAGGTGAGGTGGQGGLGGQGGNGGNGGTGATGGQGGDFALGGNGGAGGAGGSPGGSSGIQGNMGPP GTQGADG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2634c | PE_PGRS46 | - | 100% (778) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 0.0 | 52.05% (878) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv0578c | PE_PGRS7 | 0.0 | 53.26% (858) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2667c | PE_PGRS46 | 0.0 | 100.00% (778) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-164 | 48.25% (744) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01183 | - | 5e-11 | 36.96% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 7e-52 | 31.54% (501) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_2067 | - | 0.0 | 70.68% (781) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 4e-25 | 44.44% (180) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-126 | 39.64% (845) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-43 | 39.30% (313) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 49.28% (905) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-165 | 47.88% (756) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2634c|M.tuberculosis_H37Rv ----------------------------------MSFVIAVPEALTMAAS
Mb2667c|M.bovis_AF2122/97 ----------------------------------MSFVIAVPEALTMAAS
MMAR_2067|M.marinum_M ----------------------------------MSFVIAVPDAVTAAVS
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MUL_4367|M.ulcerans_Agy99 ----------------------------------MSFVSVGPGLLEAAAR
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------MSIIDFILNLFRDPVE
MAV_4827|M.avium_104 ----------------------------------MNIVLGVSMAPSSIQM
Rv2634c|M.tuberculosis_H37Rv DLANIGSTINAANAAAALPTTGVVAAAADEVSAAVAALFGSYAQSYQAFG
Mb2667c|M.bovis_AF2122/97 DLANIGSTINAANAAAALPTTGVVAAAADEVSAAVAALFGSYAQSYQAFG
MMAR_2067|M.marinum_M DLANIGSVLTTANAAAALPTTTVVAAAGDEISAAVAALFGSYAQGYQSLS
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MUL_4367|M.ulcerans_Agy99 DLAGLGAGLREANLAAAGATVGVLPAAGDEVSAAIAELFGGFGREYQAMG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTG
MAV_4827|M.avium_104 VVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAG
Rv2634c|M.tuberculosis_H37Rv ------------------------------------AQLSAFHAQFVQSL
Mb2667c|M.bovis_AF2122/97 ------------------------------------AQLSAFHAQFVQSL
MMAR_2067|M.marinum_M ------------------------------------AQAAAFHERFLQTL
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MUL_4367|M.ulcerans_Agy99 ------------------------------------ARVALLHDDFVRAL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------NPIHDLSGNLQNYY
MAV_4827|M.avium_104 ------------------------------------LQLSSIGVTWTDQL
Rv2634c|M.tuberculosis_H37Rv TNG-----------------------------------ARSYVVAEATSA
Mb2667c|M.bovis_AF2122/97 TNG-----------------------------------ARSYVVAEATSA
MMAR_2067|M.marinum_M SGG-----------------------------------AGAYAAAEAANA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MUL_4367|M.ulcerans_Agy99 TAG-----------------------------------GSAYGQAEALNM
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AAQPD---------------------------------GPSILSPSLLSP
MAV_4827|M.avium_104 EAA---------------------------------------ALRDALAA
Rv2634c|M.tuberculosis_H37Rv AP---------------------------------------LQDLLGVVN
Mb2667c|M.bovis_AF2122/97 AP---------------------------------------LQDLLGVVN
MMAR_2067|M.marinum_M SP---------------------------------------LDQLMGVVN
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MUL_4367|M.ulcerans_Agy99 WP-----------------------------------LQELEQQALGVVN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 RD-------------------------------------------NDFLS
MAV_4827|M.avium_104 RR-------------------------------------------IDNVM
Rv2634c|M.tuberculosis_H37Rv APAQALLGRPLIGNGANGADG-----TGAPGGPGGLLLGNGGNGGSGAPG
Mb2667c|M.bovis_AF2122/97 APAQALLGRPLIGNGANGADG-----TGAPGGPGGLLLGNGGNGGSGAPG
MMAR_2067|M.marinum_M APAQALLGRPLIGNGANGADG-----TGAAGGDGGILLGNGGNGGSGAAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MUL_4367|M.ulcerans_Agy99 APSMALFGRPSIGNGVDGVAG-----TGQAGGAGGILWGNGGNGGLGAAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTA
MAV_4827|M.avium_104 LVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVY
Rv2634c|M.tuberculosis_H37Rv QPGGAGGDAG---LIGNGGTGGKGGDGLVGSGAAGG--VGGRGGWLLGNG
Mb2667c|M.bovis_AF2122/97 QPGGAGGDAG---LIGNGGTGGKGGDGLVGSGAAGG--VGGRGGWLLGNG
MMAR_2067|M.marinum_M QVGGTGGAAG---LFGNGGTGGTGGE-----GAAGG--LGGRGGLLLGNG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
MUL_4367|M.ulcerans_Agy99 ANGGAGGSAG---LIGTGGVGGAGGVGAAGMTGGSGG-AGGGGGWLWGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 IGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIIN----ADHGSNVGVD
MAV_4827|M.avium_104 KQQIRAESYG-----DAAGQLSAMVAGLEKLESLPG----GLLLVGSGVD
Rv2634c|M.tuberculosis_H37Rv GTGGAGGAAGATLVG-GTGGVGGATGLIGSGGFGG---------------
Mb2667c|M.bovis_AF2122/97 GTGGAGGAAGATLVG-GTGGVGGATGLIGSGGFGG---------------
MMAR_2067|M.marinum_M GAGGVGGVGATGLAG-GTG---GAAGFLGNGGTGG---------------
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG---------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG---------------
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG---------------
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGF-----GYVLIA
MUL_4367|M.ulcerans_Agy99 GSGGAAGAGGSGGSGGWLWGNAGQTAGAGVGGAGGAGGAGDAGDQGVSGV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 QSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRN---------------
MAV_4827|M.avium_104 VAPLKQVLQTTTFLDVSVAEEPETALARGAALAAAN--------------
Rv2634c|M.tuberculosis_H37Rv ---AGGAAAGVGTTGGVGGSGG----------------------------
Mb2667c|M.bovis_AF2122/97 ---AGGAAAGVGTTGGVGGSGG----------------------------
MMAR_2067|M.marinum_M ---AGGASN-MGGDGGMGGTGG----------------------------
TH_3810|M.thermoresistible__bu -----NGYRTTDNNALDGGHGG----------------------------
Mflv_5091|M.gilvum_PYR-GCK ----AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ----AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG-----------
MSMEG_0868|M.smegmatis_MC2_155 GPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGG
MUL_4367|M.ulcerans_Agy99 APGEAGAVGFAGGAGGAGGAGGNGVGGGVNGAGGAGGAGGVGGGGGAGAS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --TTNINDSFNTDRSTNIGSGN----------------------------
MAV_4827|M.avium_104 -APLFASSTAALAYAQDPGTGAVDQYSLPDYLYVP---------------
Rv2634c|M.tuberculosis_H37Rv ---------------------VGGVFGNGG-----------------FGG
Mb2667c|M.bovis_AF2122/97 ---------------------VGGVFGNGG-----------------FGG
MMAR_2067|M.marinum_M ---------------------TGGFFGNGG-----------------FGG
TH_3810|M.thermoresistible__bu -----------------------------------------------NGG
Mflv_5091|M.gilvum_PYR-GCK -----AVGAAGAAG------TVGTAGATGGTG---------------TGA
Mvan_1264|M.vanbaalenii_PYR-1 -----AIGTAGVAG------AAGTAGATGGTG---------------VGG
MSMEG_0868|M.smegmatis_MC2_155 TVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGG
MUL_4367|M.ulcerans_Agy99 GVGAGVAGGDGGTGGAGGAAGVGGAAGTGGTG--------GAAGVAGTGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------TTNTEIGSHNQAN--------------IGT
MAV_4827|M.avium_104 ---------------------VDPEPGDDELAYS------------AVGE
Rv2634c|M.tuberculosis_H37Rv AGGLGAAGGVGGAASYFG--------------TGGGGGVGGDGAPGGDGG
Mb2667c|M.bovis_AF2122/97 AGGLGAAGGVGGAASYFG--------------TGGGGGVGGDGAPGGDGG
MMAR_2067|M.marinum_M DGGDGAVGGAGGAGSFLG--------------GGGVGGTGGVGAAGGMGG
TH_3810|M.thermoresistible__bu NVGFFSLFNLGG--------------------AGGWGGSGVDG-------
Mflv_5091|M.gilvum_PYR-GCK NGGAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 NGGAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGG
MSMEG_0868|M.smegmatis_MC2_155 DGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGG
MUL_4367|M.ulcerans_Agy99 DGGDGGAGGAGSDASLAG----------QAGFAGGSGGAGGVGGSAGAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 STSAGGSAAVGGNAGLAG-------------NAGLAGNAGLAGNAGLAGN
MAV_4827|M.avium_104 EDAESPTVVIEKLFLPED-------------SEPRRRPVLLVGSGLAVVG
Rv2634c|M.tuberculosis_H37Rv AGPL---------------LIGNGGVGGLGGAGAAGGNGGAG--------
Mb2667c|M.bovis_AF2122/97 AGPL---------------LIGNGGVGGLGGAGAAGGNGGAG--------
MMAR_2067|M.marinum_M AGP----------------LIGNGGNGGMGGAGAAGGDGGAG--------
TH_3810|M.thermoresistible__bu ----------------------VDVVGGNP--------------------
Mflv_5091|M.gilvum_PYR-GCK VGGQ----------GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGG
Mvan_1264|M.vanbaalenii_PYR-1 IGGQ----------GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGG
MSMEG_0868|M.smegmatis_MC2_155 MGEIYS--------GADGEATGISAGGDGGSATGADSLGGRGGTSWVQAG
MUL_4367|M.ulcerans_Agy99 VNGSGGDGGAGAAGGAGGASATVAGSGGVGGDGGAGGAAGGG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGLAG----------------NAGLAGNAGLAGNAGLAGNAG--------
MAV_4827|M.avium_104 ISAVL--------------ALEIALAIGIRTTGTVALQPTPN--------
Rv2634c|M.tuberculosis_H37Rv -----------------GMLLGDGGAGGQGGPAVAG--------------
Mb2667c|M.bovis_AF2122/97 -----------------GMLLGDGGAGGQGGPAVAG--------------
MMAR_2067|M.marinum_M -----------------GTLLGDGGSGGQGGAAMTG--------------
TH_3810|M.thermoresistible__bu ----------------------DGGTPG----------------------
Mflv_5091|M.gilvum_PYR-GCK QG-------------LQGGKGGDGGAGGKGGDADSMGS------------
Mvan_1264|M.vanbaalenii_PYR-1 QG-------------LQGGQGGDGGTGGTGGDATSMGE------------
MSMEG_0868|M.smegmatis_MC2_155 YGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAI
MUL_4367|M.ulcerans_Agy99 -----------VGAASLGGDGGHAGAGGAGGEGLSGGFN-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------LAGNAGLAGNAGLAGNAG-------------
MAV_4827|M.avium_104 ----------------QHLIVPTEQAPAPPPVQASAP-------------
Rv2634c|M.tuberculosis_H37Rv --------VLGGMPGAGGNGGNANWFG---------------SGGAGGQG
Mb2667c|M.bovis_AF2122/97 --------VLGGMPGAGGNGGNANWFG---------------SGGAGGQG
MMAR_2067|M.marinum_M --------ILGGLPGQGGNGGNANWFG---------------SGGAGGQG
TH_3810|M.thermoresistible__bu --------AHGESHTPGVYTDRQ---------------------------
Mflv_5091|M.gilvum_PYR-GCK ------AGATGGKGGNGGNGGRGGLFG---------------KGGNAGNG
Mvan_1264|M.vanbaalenii_PYR-1 ------AGATGGKGGNGGNGGRGSLFG---------------RGGNAGNG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNG
MUL_4367|M.ulcerans_Agy99 ------TGAAGGIGGAGGAGGTGGDSGGVG-----GVNGDGGAGGGGGRG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------LAGNAGLAGNAGLAGNAGLAG------------------NAGLA
MAV_4827|M.avium_104 ---------QPKISVPEPVAAPKPLSPP----------------------
Rv2634c|M.tuberculosis_H37Rv GT-----------------------GLAGTNGVNPGSIANPNTGANGTD-
Mb2667c|M.bovis_AF2122/97 GT-----------------------GLAGTNGVNPGSIANPNTGANGTD-
MMAR_2067|M.marinum_M GT-----------------------GLAGTDGTNPTPGATAGTGSAGAD-
TH_3810|M.thermoresistible__bu ----------------------------GEDGEDGTGTGIGGRGGNGG--
Mflv_5091|M.gilvum_PYR-GCK AD----------------------GGTGGAGGAGGTGG-TGGAGGTGG--
Mvan_1264|M.vanbaalenii_PYR-1 GN----------------------GGTGGNGGNGGTGG-TGGNGGTGG--
MSMEG_0868|M.smegmatis_MC2_155 GNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGA
MUL_4367|M.ulcerans_Agy99 GDGGSSTSTSG---------VGGAGGAGGNGGNAGFGVSAGGTGGSAGD-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GN----------------------AGLAGNAGLAGNAGLAGNAGLAGNAG
MAV_4827|M.avium_104 -----------------------VAAPLPAAPPPAAPPLPEAPPIPAAP-
Rv2634c|M.tuberculosis_H37Rv --------------NSGNGNQTGGNGGPGPAGGVGEAGGVGGQGGLGESL
Mb2667c|M.bovis_AF2122/97 --------------NSGNGNQTGGNGGPGPAGGVGEAGGVGGQGGLGESL
MMAR_2067|M.marinum_M --------------QSNNGNVTGDNGNPGDAGTGDEIGGTGGAGGLGEST
TH_3810|M.thermoresistible__bu --------------SSSGTHPMAEDG--------EHVKALDGRPGLD---
Mflv_5091|M.gilvum_PYR-GCK ---------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GT
Mvan_1264|M.vanbaalenii_PYR-1 ---------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GT
MSMEG_0868|M.smegmatis_MC2_155 SVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGE
MUL_4367|M.ulcerans_Agy99 ---------------GGAGGGAGGVDGVGGASGNGGAAGAGGAGGSGIGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------LAGNAAVAGNAAVAGNAAVAGNAAVGGVLNTGVSG
MAV_4827|M.avium_104 --------------PVVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPR
Rv2634c|M.tuberculosis_H37Rv DGNDGTGGKGGAGGTAGTDGGAGGAG----GAGGIGETDGSAGGV-----
Mb2667c|M.bovis_AF2122/97 DGNDGTGGKGGAGGTAGTDGGAGGAG----GAGGIGETDGSAGGV-----
MMAR_2067|M.marinum_M DGNSGTGGMGGGGGTAGPNGGNGGEG----GMGGEGRTDGSSGGT-----
TH_3810|M.thermoresistible__bu GGNGSHGGNGGHGGRGG-FLGIGGSG-------GWGGHGGNGGD------
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGTGGKGGTGG-TGGAGGTG----GDGGTGGTGGTGGTG-----
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGTGGKGGTGG-TGGDGGTG----GTGGTGGTGGTGGTG-----
MSMEG_0868|M.smegmatis_MC2_155 GGTGGHGGDGGRGGDGA-LGGNGGTGGVGLGNGGKGGNGGNGGNGGTY--
MUL_4367|M.ulcerans_Agy99 GIDGGAGGAGGTGGAAGFPGGGGTTG--AWGTGGAGGAGGAGGAGDHGGV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AIGGSSHVGGAINESLGGSGSVGGST-----AVGGGAHTGVGGGVS----
MAV_4827|M.avium_104 LSVPQPVQPPVRVPQPPSPPQVGGTVP-----QSPPQHQTPPGEG-----
Rv2634c|M.tuberculosis_H37Rv -----------ATGGEGGDGATG-----------GVDGGVGGAGG-----
Mb2667c|M.bovis_AF2122/97 -----------ATGGEGGDGATG-----------GVDGGVGGAGG-----
MMAR_2067|M.marinum_M -----------ATGGDGGAGADG-----------GTGGGDGGAGG-----
TH_3810|M.thermoresistible__bu ------------TDADGGNGGDG---------------GNGGSAG-----
Mflv_5091|M.gilvum_PYR-GCK -----------GTGGTGGTGGAG-----------DGTGGTGGTGG-----
Mvan_1264|M.vanbaalenii_PYR-1 -----------GTGGTGGTGGAG-----------DGLGGTGGTGG-----
MSMEG_0868|M.smegmatis_MC2_155 -----VDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDA-
MUL_4367|M.ulcerans_Agy99 GVNPGDSGTAGWAGGAGGAGGAGGSAAFNGVNGAGGAGGNGGAGGGGGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------TGVGVGSHVGGG---------ISESLGGSGSVGG-----
MAV_4827|M.avium_104 -----------TPPKPDGPGNYG--------------GGHVPTPG-----
Rv2634c|M.tuberculosis_H37Rv --------KGGQGHNTGVGD----------------AFGGDGGIGGDG--
Mb2667c|M.bovis_AF2122/97 --------KGGQGHNTGVGD----------------AFGGDGGIGGDG--
MMAR_2067|M.marinum_M --------DGGFGNNTISGA----------------AIGGNGGIGGAG--
TH_3810|M.thermoresistible__bu -------------------------------------RGGTGGLRGV---
Mflv_5091|M.gilvum_PYR-GCK --------TGGQGGQGGQGG-----------------TGGTGGQGG----
Mvan_1264|M.vanbaalenii_PYR-1 --------TGGFGGQGGQGG-----------------TGGTGGQGG----
MSMEG_0868|M.smegmatis_MC2_155 --------DGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGT---
MUL_4367|M.ulcerans_Agy99 ASGIGAGVAGGDGGTGGTGGAAG--------TGGAAGTGGTGGAAGAAGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------STAVGG------------------GAHTGVGGG---
MAV_4827|M.avium_104 -------------------------------------AGGSGGSGGG---
Rv2634c|M.tuberculosis_H37Rv --NGALGAAGGNG-----------------------GTGGAGGNGGRGGM
Mb2667c|M.bovis_AF2122/97 --NGALGAAGGNG-----------------------GTGGAGGNGGRGGM
MMAR_2067|M.marinum_M --STLQGATGGNG-----------------------DTGGAGGNGGRGGM
TH_3810|M.thermoresistible__bu -----FGINGGNG------------------------RAGLGGRGXXX--
Mflv_5091|M.gilvum_PYR-GCK -----LGGGGGTG-----------------------GQGGTGGTGGQG--
Mvan_1264|M.vanbaalenii_PYR-1 -----LGGVGGTG-----------------------GTGGTGGTGGQG--
MSMEG_0868|M.smegmatis_MC2_155 -----LGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHG--
MUL_4367|M.ulcerans_Agy99 AGDGGAGGAGGAGDDGSAG----VVSGDPGTAGKAGGAGGAGGVGGNGVA
MLBr_01183|M.leprae_Br4923 -----MPLFLNAEP-----------------------QALTAAANTL---
MAB_4284c|M.abscessus_ATCC_199 -----VSTGVGVG-----------------------SHVGGGISESLG--
MAV_4827|M.avium_104 -----HVPTPGAG-----------------------GSGGSGG-GHVP--
. .
Rv2634c|M.tuberculosis_H37Rv -----LIGNGGAGGAGGTG-------------GTGGGGAAGFAGGVGGAG
Mb2667c|M.bovis_AF2122/97 -----LIGNGGAGGAGGTG-------------GTGGGGAAGFAGGVGGAG
MMAR_2067|M.marinum_M -----FIGNGGAGGAGGTG-------------GTGGTGAAGYAGGIGGDG
TH_3810|M.thermoresistible__bu -------XGGGVGAAVRSG--------------------NGVFSGGGGTP
Mflv_5091|M.gilvum_PYR-GCK -------GTGGTGGTGGTG-------------GTGGAGGDGGLGGLGGFG
Mvan_1264|M.vanbaalenii_PYR-1 -------GTGGTGGTGGTG-------------GTGGAGGDGGLGGLGGFG
MSMEG_0868|M.smegmatis_MC2_155 -------GNGGQGTIEANGPSAVA-----SGIGAGGNGGDGIDGGLGGNG
MUL_4367|M.ulcerans_Agy99 GGVNGSGGAGGAGGAGGTGGAGASGVPASVDGGDGGAGGAGGAAGTGGSG
MLBr_01183|M.leprae_Br4923 --------EGLSAATVASN-----------------AAAAQLTTEIAPPA
MAB_4284c|M.abscessus_ATCC_199 -------GSGSVGGSTAVG--------------------GGAHTGVGGGV
MAV_4827|M.avium_104 -----TPGTGGPGGTGGSG--------------------GGHVPTPGAGT
* . . .
Rv2634c|M.tuberculosis_H37Rv GEGLTDGAGTAEGGTGGLGGLGGVGG--TGGMGGSGGVGG-------NGG
Mb2667c|M.bovis_AF2122/97 GEGLTDGAGTAEGGTGGLGGLGGVGG--TGGMGGSGGVGG-------NGG
MMAR_2067|M.marinum_M GAAFSD-AAAATGGDGAVGGVGGLGG--NGGTGGAGGAGG-------TGG
TH_3810|M.thermoresistible__bu SAGFGVPTTIQFPAGSCTSRAVSREG------------------------
Mflv_5091|M.gilvum_PYR-GCK GSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAG
Mvan_1264|M.vanbaalenii_PYR-1 GVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAG
MSMEG_0868|M.smegmatis_MC2_155 GDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGS
MUL_4367|M.ulcerans_Agy99 GSAGNTGAGGAGGAGGAGGSAASTGVNGDGGAGGAGGVGG-------LGG
MLBr_01183|M.leprae_Br4923 ADDVSILLAHFFSGHGRQYQAHASQG------------------------
MAB_4284c|M.abscessus_ATCC_199 NTGVGVGSHVGGGISESLGGSGSVGG---------------------STA
MAV_4827|M.avium_104 PGGSGGGHLPFPGAGSTPGGSG--------------------------GG
Rv2634c|M.tuberculosis_H37Rv AAGSLIGLGGGGGAGGVGGTGGIGGIG------GAGGNGGAGGAGTTTGG
Mb2667c|M.bovis_AF2122/97 AAGSLIGLGGGGGAGGVGGTGGIGGIG------GAGGNGGAGGAGTTTGG
MMAR_2067|M.marinum_M AAG-FIGIGGNGGAGGIGGVGGIGGIG------GAGGDGGIGGAATTTSG
TH_3810|M.thermoresistible__bu IMPSSRAASARAG---------------------------AACASSTSRS
Mflv_5091|M.gilvum_PYR-GCK KAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGA
Mvan_1264|M.vanbaalenii_PYR-1 TAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGS
MSMEG_0868|M.smegmatis_MC2_155 TLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGD
MUL_4367|M.ulcerans_Agy99 DSAATAGGGGAGGDGGKGGAGGAGVNGVGGGDGGKGGTGGAGGAGGAGSD
MLBr_01183|M.leprae_Br4923 -ATNHQDLIQS-----------------------------LLTSSSAYAG
MAB_4284c|M.abscessus_ATCC_199 VGGGAHTSAINDALGGSGSVGGSTAVG--------GGAHTSAINESMNSS
MAV_4827|M.avium_104 HLPTPGAGTPGGGLGGFG-----------------GGHAPAPGGGLGGGG
Rv2634c|M.tuberculosis_H37Rv GATIGGGGGTGGVG-------------GAGGTGGTGGAGGTTGG-----S
Mb2667c|M.bovis_AF2122/97 GATIGGGGGTGGVG-------------GAGGTGGTGGAGGTTGG-----S
MMAR_2067|M.marinum_M -TTTGGIGANGVLG-------------GDGGTGGDGGAGGTTGG-----S
TH_3810|M.thermoresistible__bu RRSFCCSRA-----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK TGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANG-----S
Mvan_1264|M.vanbaalenii_PYR-1 AGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANG-----S
MSMEG_0868|M.smegmatis_MC2_155 GGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNG-----G
MUL_4367|M.ulcerans_Agy99 GIIPSNGGLGGNGGNGGNGGQAFG--DGVGGAGGIGGKGGNAAIGTIVIN
MLBr_01183|M.leprae_Br4923 TETANHDSL-----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 INASHSSSMNESFG-------------SSMGSHGAAGTGFEAQG----HA
MAV_4827|M.avium_104 GHAPAPGGGLGGFG-------------GGHSGGGLGGLGGGHK-------
Rv2634c|M.tuberculosis_H37Rv GGAGGLIGWAGAAGGTG--------AGGTGGQGGL-------GGQGGNGG
Mb2667c|M.bovis_AF2122/97 GGAGGLIGWAGAAGGTG--------AGGTGGQGGL-------GGQGGNGG
MMAR_2067|M.marinum_M GGAGGVIGWAGSTGATG--------AGGTGGQGGQ-------GGAGGSGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK QGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 QGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG
MSMEG_0868|M.smegmatis_MC2_155 KGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGG
MUL_4367|M.ulcerans_Agy99 GGVGGAGGSGGLGGATEDGVGGVGCAGGAGGNGGRGDMLFTVGGSGGTGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 QGHASETAHTTLPGAEHH--------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv2634c|M.tuberculosis_H37Rv ------------NGG---TGATGGQGGDFAL--------GGNGGAGGAGG
Mb2667c|M.bovis_AF2122/97 ------------NGG---TGATGGQGGDFAL--------GGNGGAGGAGG
MMAR_2067|M.marinum_M ------------NGGTAQTGGTGGAGGDLAL--------GGQGGAGGAAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 ------------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGG
MSMEG_0868|M.smegmatis_MC2_155 NTSVWKSG-GQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGG
MUL_4367|M.ulcerans_Agy99 DGGGGGSASGSGTGGSGGTGGVGGIGGDGKLGG-----FGGDGGDGGDGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv2634c|M.tuberculosis_H37Rv ---------SPGGSSGIQ--GNMGPPGTQGADG------
Mb2667c|M.bovis_AF2122/97 ---------SPGGSSGIQ--GNMGPPGTQGADG------
MMAR_2067|M.marinum_M ---------GTGGDTGLD--GLLGVPGSNGQTGEIVP--
TH_3810|M.thermoresistible__bu ---------------------------------------
Mflv_5091|M.gilvum_PYR-GCK SGAGGAG--GAGGSGGSG--GSGGSGGSGGAAGDSDD--
Mvan_1264|M.vanbaalenii_PYR-1 SGTGGAG--GAGGSGGSG--GSGGAGGSGGAAGDSD---
MSMEG_0868|M.smegmatis_MC2_155 TTAGGSGNGGNGGNGGNG--GADGTPGTAGTTGANNP--
MUL_4367|M.ulcerans_Agy99 FGVIGGQ-GGGGGFGGLGGTGAGGAPSDKGINGEPGNPG
MLBr_01183|M.leprae_Br4923 ---------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------
MAV_4827|M.avium_104 ---------------------------------------