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M. marinum M MMAR_2067 (-)

annotation: PE-PGRS family protein
coordinates: 2489762 - 2492080
length: 772

MSFVIAVPDAVTAAVSDLANIGSVLTTANAAAALPTTTVVAAAGDEISAAVAALFGSYAQGYQSLSAQAA
AFHERFLQTLSGGAGAYAAAEAANASPLDQLMGVVNAPAQALLGRPLIGNGANGADGTGAAGGDGGILLG
NGGNGGSGAAGQVGGTGGAAGLFGNGGTGGTGGEGAAGGLGGRGGLLLGNGGAGGVGGVGATGLAGGTGG
AAGFLGNGGTGGAGGASNMGGDGGMGGTGGTGGFFGNGGFGGDGGDGAVGGAGGAGSFLGGGGVGGTGGV
GAAGGMGGAGPLIGNGGNGGMGGAGAAGGDGGAGGTLLGDGGSGGQGGAAMTGILGGLPGQGGNGGNANW
FGSGGAGGQGGTGLAGTDGTNPTPGATAGTGSAGADQSNNGNVTGDNGNPGDAGTGDEIGGTGGAGGLGE
STDGNSGTGGMGGGGGTAGPNGGNGGEGGMGGEGRTDGSSGGTATGGDGGAGADGGTGGGDGGAGGDGGF
GNNTISGAAIGGNGGIGGAGSTLQGATGGNGDTGGAGGNGGRGGMFIGNGGAGGAGGTGGTGGTGAAGYA
GGIGGDGGAAFSDAAAATGGDGAVGGVGGLGGNGGTGGAGGAGGTGGAAGFIGIGGNGGAGGIGGVGGIG
GIGGAGGDGGIGGAATTTSGTTTGGIGANGVLGGDGGTGGDGGAGGTTGGSGGAGGVIGWAGSTGATGAG
GTGGQGGQGGAGGSGGNGGTAQTGGTGGAGGDLALGGQGGAGGAAGGTGGDTGLDGLLGVPGSNGQTGEI
VP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2067--100% (772)PE-PGRS family protein
M. marinum MMMAR_2033-0.050.18% (855) PE-PGRS family protein
M. marinum MMMAR_3758-0.050.72% (836) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2667cPE_PGRS460.070.68% (781) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-1e-15846.90% (742) triple helix repeat-containing collagen
M. tuberculosis H37RvRv2634cPE_PGRS460.070.68% (781) PE-PGRS family protein
M. leprae Br4923MLBr_01183-7e-1235.42% (96) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-6e-4733.88% (484) hypothetical protein MAB_4284c
M. avium 104MAV_1346-3e-2436.06% (269) PE family protein
M. smegmatis MC2 155MSMEG_0868-1e-13040.58% (892) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-1e-4441.14% (299) PUTATIVE -
M. ulcerans Agy99MUL_4367-0.046.11% (926) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-1e-15646.16% (730) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2667c|M.bovis_AF2122/97           ----------------------------------MSFVIAVPEALTMAAS
Rv2634c|M.tuberculosis_H37Rv        ----------------------------------MSFVIAVPEALTMAAS
MMAR_2067|M.marinum_M               ----------------------------------MSFVIAVPDAVTAAVS
MUL_4367|M.ulcerans_Agy99           ----------------------------------MSFVSVGPGLLEAAAR
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------MSIIDFILNLFRDPVE
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2667c|M.bovis_AF2122/97           DLANIGSTINAANAAAALPTTGVVAAAADEVSAAVAALFGSYAQSYQAFG
Rv2634c|M.tuberculosis_H37Rv        DLANIGSTINAANAAAALPTTGVVAAAADEVSAAVAALFGSYAQSYQAFG
MMAR_2067|M.marinum_M               DLANIGSVLTTANAAAALPTTTVVAAAGDEISAAVAALFGSYAQGYQSLS
MUL_4367|M.ulcerans_Agy99           DLAGLGAGLREANLAAAGATVGVLPAAGDEVSAAIAELFGGFGREYQAMG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTG
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2667c|M.bovis_AF2122/97           --------------------------AQLSAFHAQFVQSLTNGARSYVVA
Rv2634c|M.tuberculosis_H37Rv        --------------------------AQLSAFHAQFVQSLTNGARSYVVA
MMAR_2067|M.marinum_M               --------------------------AQAAAFHERFLQTLSGGAGAYAAA
MUL_4367|M.ulcerans_Agy99           --------------------------ARVALLHDDFVRALTAGGSAYGQA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------NPIHDLSGNLQNYYAAQPDGPSILSPS
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2667c|M.bovis_AF2122/97           ----------------------------------------EATSAAPLQD
Rv2634c|M.tuberculosis_H37Rv        ----------------------------------------EATSAAPLQD
MMAR_2067|M.marinum_M               ----------------------------------------EAANASPLDQ
MUL_4367|M.ulcerans_Agy99           ----------------------------------------EALNMWPLQE
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------LLSPRDNDFLSH
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2667c|M.bovis_AF2122/97           L------------------------LGVVNAPAQALLGRPLIGNGANGAD
Rv2634c|M.tuberculosis_H37Rv        L------------------------LGVVNAPAQALLGRPLIGNGANGAD
MMAR_2067|M.marinum_M               L------------------------MGVVNAPAQALLGRPLIGNGANGAD
MUL_4367|M.ulcerans_Agy99           LE--------------------QQALGVVNAPSMALFGRPSIGNGVDGVA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      N---------------------DTDFASHNPIASGNQVMSPSGNVDSFNR
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          QN------GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGG--NGGNGGNG
Mvan_1264|M.vanbaalenii_PYR-1       QN------GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGG--NGGNGGNG
MSMEG_0868|M.smegmatis_MC2_155      DNPN-GGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG---NGGNGGVG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2667c|M.bovis_AF2122/97           GTGAPGGPGGLLLGNGGNGG-SGAPGQPGGAGGDAGLIGNGGTGGKGGDG
Rv2634c|M.tuberculosis_H37Rv        GTGAPGGPGGLLLGNGGNGG-SGAPGQPGGAGGDAGLIGNGGTGGKGGDG
MMAR_2067|M.marinum_M               GTGAAGGDGGILLGNGGNGG-SGAAGQVGGTGGAAGLFGNGGTGGTGGE-
MUL_4367|M.ulcerans_Agy99           GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGGVG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVR
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          LG---GGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--------
Mvan_1264|M.vanbaalenii_PYR-1       LG---SGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--------
MSMEG_0868|M.smegmatis_MC2_155      WA---GLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGG------
TH_3810|M.thermoresistible__bu      -V---DGDGGSGGRTGLFSKLSRGGDGGDGGLG-----------------
Mb2667c|M.bovis_AF2122/97           LV-GSGAAGGVGGRGG--WLLGNGGTGGAGGAAGAT--------------
Rv2634c|M.tuberculosis_H37Rv        LV-GSGAAGGVGGRGG--WLLGNGGTGGAGGAAGAT--------------
MMAR_2067|M.marinum_M               -----GAAGGLGGRGG--LLLGNGGAGGVGGVGATG--------------
MUL_4367|M.ulcerans_Agy99           AAGMTGGSGGAGGGGG--WLWGAGGSGGAAGAGGSGGSGGWLWGNAGQTA
MLBr_01183|M.leprae_Br4923          -----------------MPLFLNAEPQALTAAAN----------------
MAV_1346|M.avium_104                -----------------MS-FVTTRPEALLAVAS----------------
MAB_4284c|M.abscessus_ATCC_199      DSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSAD--------------
                                                                  . .                 

Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------APGVAGATGATG----
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------APGVAGATGATG----
MSMEG_0868|M.smegmatis_MC2_155      ----------------------------------TGGTGGTGGGTG----
TH_3810|M.thermoresistible__bu      ------------------------------------GNGGHGGGTG----
Mb2667c|M.bovis_AF2122/97           ---------------------------------LVGGTGGVGGATG----
Rv2634c|M.tuberculosis_H37Rv        ---------------------------------LVGGTGGVGGATG----
MMAR_2067|M.marinum_M               ---------------------------------LAGGTG---GAAG----
MUL_4367|M.ulcerans_Agy99           GAGVGGAGGAGGAGDAGDQGVSGVAPGEAGAVGFAGGAGGAGGAGGNGVG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------------------IDKSVTVVDDHSQ----
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----VTSGVVGGNG------------------EDAVGYGATGAAGAAGAA
Mvan_1264|M.vanbaalenii_PYR-1       ----VTSNVTGGNG------------------ADAVGYGATGAAGAAGAA
MSMEG_0868|M.smegmatis_MC2_155      ----GTGGIGGTGG------------------GLFGLLGHSGSTGAAGAA
TH_3810|M.thermoresistible__bu      ----IIS--------------------------------------LLSLA
Mb2667c|M.bovis_AF2122/97           --LIGSGGFGGAG---------------------------GAAAGVGTTG
Rv2634c|M.tuberculosis_H37Rv        --LIGSGGFGGAG---------------------------GAAAGVGTTG
MMAR_2067|M.marinum_M               --FLGNGGTGGAG---------------------------GASN-MGGDG
MUL_4367|M.ulcerans_Agy99           GGVNGAGGAGGAGGVGGGGGAGASGVGAGVAGGDGGTGGAGGAAGVGGAA
MLBr_01183|M.leprae_Br4923          --------------------------------------------TLEGLS
MAV_1346|M.avium_104                --------------------------------------------MLEGLG
MAB_4284c|M.abscessus_ATCC_199      ---RNTTNINDSFN-----------------------------TDRSTNI
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GAAGAAG--------------AVGSAGAAGEAGETGTWG---------NA
Mvan_1264|M.vanbaalenii_PYR-1       GAAGKAG--------------AVGSAGTAGSAGAPGVWG---------NA
MSMEG_0868|M.smegmatis_MC2_155      GNGGDGGNGGFGYVLIAGPNVTVGSETRGGTGGAGGTGGQS-------TA
TH_3810|M.thermoresistible__bu      GNGGNGG---------------NGYRTTDNNALDGGHGG-----------
Mb2667c|M.bovis_AF2122/97           GVGGSGG--------------VGGVFGNGGFGGAGGLGAAG---------
Rv2634c|M.tuberculosis_H37Rv        GVGGSGG--------------VGGVFGNGGFGGAGGLGAAG---------
MMAR_2067|M.marinum_M               GMGGTGG--------------TGGFFGNGGFGGDGGDGAVG---------
MUL_4367|M.ulcerans_Agy99           GTGGTGG--------------AAGVAGTGGDGGDGGAGGAGSDASLAGQA
MLBr_01183|M.leprae_Br4923          AATVASN--------------AAAAQLTTEIAP-----------------
MAV_1346|M.avium_104                SSMDAQN--------------AAAAAPTTSIAP-----------------
MAB_4284c|M.abscessus_ATCC_199      GSGNTTN-------------TEIGSHNQANIGTSTSAGG-----------
                                    .     .                .       .                  

Mflv_5091|M.gilvum_PYR-GCK          GLPGKAGDAGGAG----------------AVGAAGAAG------TVGTAG
Mvan_1264|M.vanbaalenii_PYR-1       GLPGAAGAAGGAG----------------AIGTAGVAG------AAGTAG
MSMEG_0868|M.smegmatis_MC2_155      AGPGKGGGGGGGGGGAILIGANGGTVDGHAIGGNGGNGGNGSTTAAGGNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2667c|M.bovis_AF2122/97           -------GVGGAAS---------------YFGTGGG-------GGVGGDG
Rv2634c|M.tuberculosis_H37Rv        -------GVGGAAS---------------YFGTGGG-------GGVGGDG
MMAR_2067|M.marinum_M               -------GAGGAGS---------------FLGGGGV-------GGTGGVG
MUL_4367|M.ulcerans_Agy99           GFAGGSGGAGGVGG---------------SAGAGGVNG----SGGDGGAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ATGGTG---------------TGANGGAGGVGGVGGTGAAG---------
Mvan_1264|M.vanbaalenii_PYR-1       ATGGTG---------------VGGNGGAGQAGGIGGTGAAG---------
MSMEG_0868|M.smegmatis_MC2_155      GTGGTGRVIAEGTGSTAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNG
TH_3810|M.thermoresistible__bu      ---------------------NGGNVGFFSLFNLGG--------------
Mb2667c|M.bovis_AF2122/97           APGGDG-------GAGPLLIGNGGVGGLGGAGAAGGNGGAGG--------
Rv2634c|M.tuberculosis_H37Rv        APGGDG-------GAGPLLIGNGGVGGLGGAGAAGGNGGAGG--------
MMAR_2067|M.marinum_M               AAGGMG-------GAGP-LIGNGGNGGMGGAGAAGGDGGAGG--------
MUL_4367|M.ulcerans_Agy99           AAGGAG-------GASATVAGSGGVGGDGGAGGAAGGGVGAA--------
MLBr_01183|M.leprae_Br4923          --------------------PAADDVSILLAHFFSGHGRQYQ--------
MAV_1346|M.avium_104                --------------------AAADEVSALQAAQFSAYGTWYQ--------
MAB_4284c|M.abscessus_ATCC_199      ------------------SAAVGGNAGLAGNAGLAGNAGLAG--------
                                                          .   .       ..              

Mflv_5091|M.gilvum_PYR-GCK          -----AAGGAGGLGETGTTGGAGGVGGQ--GTAGGTGGVGGIGGAGSTGA
Mvan_1264|M.vanbaalenii_PYR-1       -----AAGQAGTAGETGVTGGVGGIGGQ--GTEGGTGGVGGVGGVGATGG
MSMEG_0868|M.smegmatis_MC2_155      AVSGTATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATG
TH_3810|M.thermoresistible__bu      ------AGGWGGSGVDG---------------------VDVVGGNP----
Mb2667c|M.bovis_AF2122/97           -----MLLGDGGAGGQGGP-----------AVAGVLGGMPGAGGNGGNAN
Rv2634c|M.tuberculosis_H37Rv        -----MLLGDGGAGGQGGP-----------AVAGVLGGMPGAGGNGGNAN
MMAR_2067|M.marinum_M               -----TLLGDGGSGGQGGA-----------AMTGILGGLPGQGGNGGNAN
MUL_4367|M.ulcerans_Agy99           -----SLGGDGGHAGAGGAGGEGLSGGFNTGAAGGIGGAGGAGGTGGDSG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----NAGLAGNAGLAGNAG---------------LAGNAGLAGNAGLAG
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          VGGVGGKG----IQGGQG-------------LQGGKGGDGGAGGKGGDAD
Mvan_1264|M.vanbaalenii_PYR-1       AGGVGGKG----IQGGQG-------------LQGGQGGDGGTGGTGGDAT
MSMEG_0868|M.smegmatis_MC2_155      ADSLGGRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDAL
TH_3810|M.thermoresistible__bu      --------------------------------------DGGTPG------
Mb2667c|M.bovis_AF2122/97           WFG----SGGAGGQGGTGLAG-----TNGVNPGSIANPNTGAN--GTDNS
Rv2634c|M.tuberculosis_H37Rv        WFG----SGGAGGQGGTGLAG-----TNGVNPGSIANPNTGAN--GTDNS
MMAR_2067|M.marinum_M               WFG----SGGAGGQGGTGLAG-----TDGTNPTPGATAGTGSA--GADQS
MUL_4367|M.ulcerans_Agy99           GVGGVNGDGGAGGGGGRGGDGGSSTSTSGVGGAGGAGGNGGNAGFGVSAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          SMGS------------------AGATGGKGGNGGNGGRGGLFG-------
Mvan_1264|M.vanbaalenii_PYR-1       SMGE------------------AGATGGKGGNGGNGGRGSLFG-------
MSMEG_0868|M.smegmatis_MC2_155      VMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSA
TH_3810|M.thermoresistible__bu      ------------------------AHGESHTPGVYTDRQ-----------
Mb2667c|M.bovis_AF2122/97           GNGN-----------------QTGGNGGPGPAGGVGEAG-----------
Rv2634c|M.tuberculosis_H37Rv        GNGN-----------------QTGGNGGPGPAGGVGEAG-----------
MMAR_2067|M.marinum_M               NNGN-----------------VTGDNGNPGDAGTGDEIG-----------
MUL_4367|M.ulcerans_Agy99           GTGG-----------------SAGDGGAGGGAGGVDGVGGASG-------
MLBr_01183|M.leprae_Br4923          ------------------------AHASQGATNHQDLIQS----------
MAV_1346|M.avium_104                ------------------------QVSAQAKAIHQTLVQN----------
MAB_4284c|M.abscessus_ATCC_199      ------------------------NAGLAGNAGLAGNAG-----------
                                                              .                       

Mflv_5091|M.gilvum_PYR-GCK          --------KGGNAGNGAD----------------------GGTGGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1       --------RGGNAGNGGN----------------------GGTGGNGGNG
MSMEG_0868|M.smegmatis_MC2_155      TSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFN
TH_3810|M.thermoresistible__bu      --------------------------------------------GEDGED
Mb2667c|M.bovis_AF2122/97           -------------GVGGQG---------------------GLGESLDGND
Rv2634c|M.tuberculosis_H37Rv        -------------GVGGQG---------------------GLGESLDGND
MMAR_2067|M.marinum_M               -------------GTGGAG---------------------GLGESTDGNS
MUL_4367|M.ulcerans_Agy99           --------NGGAAGAGGAG---------------------GSGIGAGIDG
MLBr_01183|M.leprae_Br4923          -----------------------------------------LLTSSSAYA
MAV_1346|M.avium_104                -----------------------------------------LDTNADSYG
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------------LAGNAGLA
                                                                                .     

Mflv_5091|M.gilvum_PYR-GCK          GTGG-TGGAGGTGG-----------------TGGTGGIGGAGSTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1       GTGG-TGGNGGTGG-----------------TGGTGGIGGAGSTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155      GTGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGA
TH_3810|M.thermoresistible__bu      GTGTGIGGRGGNGG----------------SSSGTHPMAEDG--------
Mb2667c|M.bovis_AF2122/97           GTGG-KGGAGGTAGT----------------DGGAGGAGGAGGIGETDGS
Rv2634c|M.tuberculosis_H37Rv        GTGG-KGGAGGTAGT----------------DGGAGGAGGAGGIGETDGS
MMAR_2067|M.marinum_M               GTGG-MGGGGGTAGP----------------NGGNGGEGGMGGEGRTDGS
MUL_4367|M.ulcerans_Agy99           GAGG-AGGTGGAAGFPG-----GGGTTGAWGTGGAGGAGGAGGAGDHGGV
MLBr_01183|M.leprae_Br4923          GTETAN--------------------------------------------
MAV_1346|M.avium_104                ATEAANRVNTSAAAL--------------------------------QGL
MAB_4284c|M.abscessus_ATCC_199      GNAGLAGNAGLAGNAG---------------LAGNAGLAGNAGLAGNAGL
                                    .                                                 

Mflv_5091|M.gilvum_PYR-GCK          GGTGGTGGTGGTG-GTGGTGGTGGT---------GGKGGTGGTGGAGGTG
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGTGGTGGTG-GTGGTGGTGGT---------GGKGGTGGTGGDGGTG
MSMEG_0868|M.smegmatis_MC2_155      NGNGGAGGAGGVSEGEGGTGGHGGD---------GGRGGDGALGGNGGTG
TH_3810|M.thermoresistible__bu      EHVKALDGRPGLD---GGNGSHGGN---------GGHGGRGGFLGIGGSG
Mb2667c|M.bovis_AF2122/97           -----AGGVA--TGGEGGDGATG-----------GVDGGVGGAGGKGGQG
Rv2634c|M.tuberculosis_H37Rv        -----AGGVA--TGGEGGDGATG-----------GVDGGVGGAGGKGGQG
MMAR_2067|M.marinum_M               -----SGGTA--TGGDGGAGADG-----------GTGGGDGGAGGDGGFG
MUL_4367|M.ulcerans_Agy99           GVNPGDSGTAGWAGGAGGAGGAGGSAAFNGVNGAGGAGGNGGAGGGGGAG
MLBr_01183|M.leprae_Br4923          ------------------HDSL----------------------------
MAV_1346|M.avium_104                APNVIPNAAPAADPPPAGTTSLGTS------------IGWAQNVGAAASD
MAB_4284c|M.abscessus_ATCC_199      AGNAGLAGNAGLAGNAGLAGNAAVAG-------NAAVAGNAAVAGNAAVG
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----GDGGTGGTGGTGGTG----------------GTGGTG--GTGGAG-
Mvan_1264|M.vanbaalenii_PYR-1       ----GTGGTGGTGGTGGTG----------------GTGGTG--GTGGAG-
MSMEG_0868|M.smegmatis_MC2_155      GVGLGNGGKGGNGGNGGNGGTY-------VDPSHTGAGGNG--GNGGAGR
TH_3810|M.thermoresistible__bu      -------GWGGHGGNGGD------------------TDADG--GNGGDG-
Mb2667c|M.bovis_AF2122/97           HNTGVGDAFGGDGGIGGDG--------------NGALGAAG--GNGGTG-
Rv2634c|M.tuberculosis_H37Rv        HNTGVGDAFGGDGGIGGDG--------------NGALGAAG--GNGGTG-
MMAR_2067|M.marinum_M               NNTISGAAIGGNGGIGGAG--------------STLQGATG--GNGDTG-
MUL_4367|M.ulcerans_Agy99           ASGIGAGVAGGDGGTGGTGGAAGTGGAAGTGGTGGAAGAAGSAGDGGAG-
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                FITLGEGQFAPVPGAAGIP-----------------NFNPGLTAATTAG-
MAB_4284c|M.abscessus_ATCC_199      G-VLNTGVSGAIGGSSHVG----------------GAINESLGGSGSVG-
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----------DGTGGTGGTGG----TGGQGGQGGQGG-------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------DGLGGTGGTGG----TGGFGGQGGQGG-------------
MSMEG_0868|M.smegmatis_MC2_155      IRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNA
TH_3810|M.thermoresistible__bu      --------------GNGGSAG-----------------------------
Mb2667c|M.bovis_AF2122/97           --------------GAGGNG------GRGGMLIGN---------------
Rv2634c|M.tuberculosis_H37Rv        --------------GAGGNG------GRGGMLIGN---------------
MMAR_2067|M.marinum_M               --------------GAGGNG------GRGGMFIGN---------------
MUL_4367|M.ulcerans_Agy99           --------------GAGGAGD----DGSAGVVSGDPGTA-----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                -----------------PPAP-----------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------GSTAVGG-----------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----TGGTGGQGG-LGGGGGTG-----------------------GQGGT
Mvan_1264|M.vanbaalenii_PYR-1       ----TGGTGGQGG-LGGVGGTG-----------------------GTGGT
MSMEG_0868|M.smegmatis_MC2_155      SGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGS
TH_3810|M.thermoresistible__bu      ----RGGTGGLRGVFGINGGNG------------------------RAGL
Mb2667c|M.bovis_AF2122/97           -----GGAGGAGG----TGG--------------------------TGGG
Rv2634c|M.tuberculosis_H37Rv        -----GGAGGAGG----TGG--------------------------TGGG
MMAR_2067|M.marinum_M               -----GGAGGAGG----TGG--------------------------TGGT
MUL_4367|M.ulcerans_Agy99           --GKAGGAGGAGG----VGGNGVAG--------------------GVNGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                -----AAPAAAAG---------------------------------APVL
MAB_4284c|M.abscessus_ATCC_199      -----GAHTGVGGGVSTGVGVG-----------------------SHVGG
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGSGGT
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGVGGT
MSMEG_0868|M.smegmatis_MC2_155      GINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVV
TH_3810|M.thermoresistible__bu      GGRGXXXXGGGVG---------------AAVRSGNGVFSGGGGTPSAGFG
Mb2667c|M.bovis_AF2122/97           GAAGFAGGVGGAGGEGLTDG-------AGTAEGGTGGLGGLGGVGGTGGM
Rv2634c|M.tuberculosis_H37Rv        GAAGFAGGVGGAGGEGLTDG-------AGTAEGGTGGLGGLGGVGGTGGM
MMAR_2067|M.marinum_M               GAAGYAGGIGGDGGAAFSD--------AAAATGGDGAVGGVGGLGGNGGT
MUL_4367|M.ulcerans_Agy99           GGAGGAGGAGGTGGAGASGV-------PASVDGGDGGAGGAGGAAGTGGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                ASMGRGPSIGGLSVPPSWAP-------GGVAPAANATPAQLVGAGFTSAA
MAB_4284c|M.abscessus_ATCC_199      GISESLGGSGSVGGSTAVGG-------GAHTGVGGGVSTGVGVGSHVGGG
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GG------QGGLGGPGGSTGG--AGGAGG--QAGTAGKGGLFG----GSG
Mvan_1264|M.vanbaalenii_PYR-1       GG------QGGQGGPGGSTGG--AGGAGG--QAGVAGKGGLFG----GSG
MSMEG_0868|M.smegmatis_MC2_155      NT------TANAANPGSATGT--ATGGDGGKATGTASQGGNGGPSWVQSG
TH_3810|M.thermoresistible__bu      VP------TTIQFPAGSCTSR--AVSREG---------------------
Mb2667c|M.bovis_AF2122/97           GG------SGGVGGNGGAAGS--LIGLGGGGGAGGVGGTGGIGG------
Rv2634c|M.tuberculosis_H37Rv        GG------SGGVGGNGGAAGS--LIGLGGGGGAGGVGGTGGIGG------
MMAR_2067|M.marinum_M               GG------AGGAGGTGGAAG---FIGIGGNGGAGGIGGVGGIGG------
MUL_4367|M.ulcerans_Agy99           GGSAGNTGAGGAGGAGGAGGSAASTGVNGDGGAGGAGGVGGLGGDSAATA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                PD---------TAPVTAVPGG-----------------------------
MAB_4284c|M.abscessus_ATCC_199      IS-------ESLGGSGSVGGSTAVGGGAHTGVGGGVNTGVGVGS------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          SAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAG-
Mvan_1264|M.vanbaalenii_PYR-1       SAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASG-
MSMEG_0868|M.smegmatis_MC2_155      YGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTA-
TH_3810|M.thermoresistible__bu      ---IMPSSRAASARAG---------------------------AACASS-
Mb2667c|M.bovis_AF2122/97           ----IGGAGGNGGAGGAGTT-----------------TGGGATIGGGGG-
Rv2634c|M.tuberculosis_H37Rv        ----IGGAGGNGGAGGAGTT-----------------TGGGATIGGGGG-
MMAR_2067|M.marinum_M               ----IGGAGGDGGIGGAATT-----------------TSG-TTTGGIGA-
MUL_4367|M.ulcerans_Agy99           GGGGAGGDGGKGGAGGAGVNGVGGGDGGKG------GTGGAGGAGGAGSD
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                -----VPSMATAGRGGYGLG------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----HVGGGISESLGGSGSVG-----------------GSTAVGGGAHT-
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -----KAGATGAAGAAGAAG--------SAG----------------TTG
Mvan_1264|M.vanbaalenii_PYR-1       -----AQGSAGSAGSAGVAG--------SAG----------------TTG
MSMEG_0868|M.smegmatis_MC2_155      -----TGGDGGAATTAGATG--------GAGGFSNIAAIHGA-----ITD
TH_3810|M.thermoresistible__bu      -----TSRSRRSFCCSRA--------------------------------
Mb2667c|M.bovis_AF2122/97           -----TGGVGGAGGTGGTGG---------AG-----------------GT
Rv2634c|M.tuberculosis_H37Rv        -----TGGVGGAGGTGGTGG---------AG-----------------GT
MMAR_2067|M.marinum_M               -----NGVLGGDGGTGGDGG---------AG-----------------GT
MUL_4367|M.ulcerans_Agy99           GIIPSNGGLGGNGGNGGNGGQAFGDGVGGAGGIGGKGGNAAIGTIVINGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                -----APRYGVKPTVMPKPAI-----------------------------
MAB_4284c|M.abscessus_ATCC_199      -----SAINDALGGSGSVGG---------------------------STA
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          AQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDA
Mvan_1264|M.vanbaalenii_PYR-1       AQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDP
MSMEG_0868|M.smegmatis_MC2_155      STAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2667c|M.bovis_AF2122/97           TGGSGGAGGL----------IGWAGAAGGTG-----------AGGTGGQG
Rv2634c|M.tuberculosis_H37Rv        TGGSGGAGGL----------IGWAGAAGGTG-----------AGGTGGQG
MMAR_2067|M.marinum_M               TGGSGGAGGV----------IGWAGSTGATG-----------AGGTGGQG
MUL_4367|M.ulcerans_Agy99           VGGAGGSGGLGGATEDGVGGVGCAGGAGGNGGRGDMLFTVGGSGGTGGDG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VGGGAHTSAINESMNSSINASHSSSMNESFG----------SSMGSHGAA
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE---
Mvan_1264|M.vanbaalenii_PYR-1       GSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE---
MSMEG_0868|M.smegmatis_MC2_155      GVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2667c|M.bovis_AF2122/97           G-------LGGQGGNGG-----------NGG---TGATGGQGGDFAL---
Rv2634c|M.tuberculosis_H37Rv        G-------LGGQGGNGG-----------NGG---TGATGGQGGDFAL---
MMAR_2067|M.marinum_M               G-------QGGAGGSGG-----------NGGTAQTGGTGGAGGDLAL---
MUL_4367|M.ulcerans_Agy99           G-------GGGSASGSG-----------TGGSGGTGGVGGIGGDGKL---
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      G----------------------------TGFEAQGHAQGHASETAH---
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -----GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGS-----GGSGGA
Mvan_1264|M.vanbaalenii_PYR-1       -----GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGA-----GGSGGA
MSMEG_0868|M.smegmatis_MC2_155      GGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGT-----PGTAGT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2667c|M.bovis_AF2122/97           -----GGNGGAGGAGG---------SPGGSSGIQGNMGP-----PGTQGA
Rv2634c|M.tuberculosis_H37Rv        -----GGNGGAGGAGG---------SPGGSSGIQGNMGP-----PGTQGA
MMAR_2067|M.marinum_M               -----GGQGGAGGAAG---------GTGGDTGLDGLLGV-----PGSNGQ
MUL_4367|M.ulcerans_Agy99           -----GGFGGDGGDGGDGGFGVI-GGQGGGGGFGGLGGTGAGGAPSDKGI
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----TTLPGAEHH------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          AGDSDD--
Mvan_1264|M.vanbaalenii_PYR-1       AGDSD---
MSMEG_0868|M.smegmatis_MC2_155      TGANNP--
TH_3810|M.thermoresistible__bu      --------
Mb2667c|M.bovis_AF2122/97           DG------
Rv2634c|M.tuberculosis_H37Rv        DG------
MMAR_2067|M.marinum_M               TGEIVP--
MUL_4367|M.ulcerans_Agy99           NGEPGNPG
MLBr_01183|M.leprae_Br4923          --------
MAV_1346|M.avium_104                --------
MAB_4284c|M.abscessus_ATCC_199      --------