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LPKSWDPAAMESAIYQKWLDAGYFTADPTSTKPAYSIVLPPPNVTGSLHMGHALEHTMMDALTRRKRMQG YEVLWQPGTDHAGIATQSVVEQQLAVDGKTKEDLGRELFVDKVWDWKRESGGAIGGQMRRLGDGVDWSRD RFTMDEGLSRAVRTIFKRLYDAGLIYRAERLVNWSPVLQTAISDLEVNYRDVEGELVSFRYGSLDDSQPH IVVATTRVETMLGDTAIAVHPDDERYRHLVGTSLAHPFVDRELAIVADEHVDPEFGTGAVKVTPAHDPND FEIGVRHQLPMPSILDTKGRIVDTGTRFDGMDRFEARVAVRQALAAQGRVVEEKRPYLHSVGHSERSGEP IEPRLSLQWWVRVESLAKAAGDAVRNGDTVIHPASMEPRWFSWVDDMHDWCISRQLWWGHRIPIWYGPDG EQVCVGPDETPPQGWEQDPDVLDTWFSSALWPFSTLGWPDKTAELEKFYPTSVLVTGYDILFFWVARMMM FGTFVGDDAAITLDGRRGPQVPFTDVFLHGLIRDESGRKMSKSKGNVIDPLDWVEMFGADALRFTLARGA SPGGDLAVSEDAVRASRNFGTKLFNATRYALLNGAAPAPLPSPNELTDADRWILGRLEEVRAEVDSAFDG YEFSRACESLYHFAWDEFCDWYLELAKTQLAQGLTHTTAVLAAGLDTLLRLLHPVIPFLTEALWLALTGR ESLVSADWPEPSGISVDLVAAQRINDMQKLVTEVRRFRSDQGLADRQKVPARMHGVRDSDLSNQVAAVTS LAWLTEPGPDFEPSVSLEVRLGPEMNRTVVVELDTSGTIDVAAERRRLEKELAGAQKELASTAAKLANAD FLAKAPDAVIAKIRDRQRVAQQETERITTRLAALQ*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv2448c | valS | - | 100% (876) | valyl-tRNA synthetase |
M. tuberculosis H37Rv | Rv1536 | ileS | 5e-50 | 24.40% (832) | isoleucyl-tRNA synthetase |
M. tuberculosis H37Rv | Rv1007c | metG | 6e-15 | 26.87% (268) | methionyl-tRNA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2475c | valS | 0.0 | 100.00% (876) | valyl-tRNA synthetase |
M. gilvum PYR-GCK | Mflv_2630 | valS | 0.0 | 79.66% (880) | valyl-tRNA synthetase |
M. leprae Br4923 | MLBr_01472 | valS | 0.0 | 85.39% (876) | valyl-tRNA synthetase |
M. abscessus ATCC 19977 | MAB_1603 | valS | 0.0 | 78.60% (874) | valyl-tRNA synthetase |
M. marinum M | MMAR_3772 | valS | 0.0 | 90.29% (875) | valyl-tRNA synthetase protein ValS |
M. avium 104 | MAV_1724 | valS | 0.0 | 88.34% (875) | valyl-tRNA synthetase |
M. smegmatis MC2 155 | MSMEG_4630 | valS | 0.0 | 82.95% (827) | valyl-tRNA synthetase |
M. thermoresistible (build 8) | TH_0609 | valS | 0.0 | 79.09% (875) | PROBABLE VALYL-tRNA SYNTHASE PROTEIN VALS (VALYL-tRNA |
M. ulcerans Agy99 | MUL_3719 | valS | 0.0 | 90.17% (875) | valyl-tRNA synthetase |
M. vanbaalenii PYR-1 | Mvan_3951 | valS | 0.0 | 81.76% (877) | valyl-tRNA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2630|M.gilvum_PYR-GCK MTSQPHANGDARSVPELDALPKSWDPGTVESDLYDGWVEAGYFTADPSSD Mvan_3951|M.vanbaalenii_PYR-1 MTSQPTANGDAPRAPELDALPKSWDPGAVESDLYDGWVKAGYFTADPTSA MSMEG_4630|M.smegmatis_MC2_155 MTASPENR--------ADALPKSWDPGAVEAELYQGWVDAGYFTADPASD TH_0609|M.thermoresistible__bu ----------------VESLPKTWDPAAVETELYEGWVRAGYFTADPSSS MAB_1603|M.abscessus_ATCC_1997 MTQTPDTN-------AASSLPTSWDPGAVEAELYQGWVDAGYFTADPSSD Rv2448c|M.tuberculosis_H37Rv ------------------MLPKSWDPAAMESAIYQKWLDAGYFTADPTST Mb2475c|M.bovis_AF2122/97 ------------------MLPKSWDPAAMESAIYQKWLDAGYFTADPTST MMAR_3772|M.marinum_M MTASADSA--------ADQLPKSWDPAAMEGDIYQKWADAGYFVADPTSS MUL_3719|M.ulcerans_Agy99 MTASADSA--------ADQLPKSWDPAAMEGDIYQKWADAGYFVADPTSS MLBr_01472|M.leprae_Br4923 MTTSPSSS--------ADLLPKSWDPGAMESVIYQKWLNSGYFAADPAST MAV_1724|M.avium_104 MTAS-RSP--------ATDLPKSWDPAAAEYAIYRQWVDAGYFTANPASD **.:***.: * :* * :***.*:*:* Mflv_2630|M.gilvum_PYR-GCK KPAYSIVLPPPNVTGSLHMGHALDHTLMDALTRRKRMQGYEVLWLPGMDH Mvan_3951|M.vanbaalenii_PYR-1 KPAYSIVLPPPNVTGSLHMGHALDHTLMDALTRRKRMQGYEVLWLPGMDH MSMEG_4630|M.smegmatis_MC2_155 KPPYSIVLPPPNVTGSLHMGHALDHTLMDVLTRRKRMQGYEVLWLPGMDH TH_0609|M.thermoresistible__bu KPSYSIVLPPPNVTGSLHMGHALDHTLMDALTRRKRMQGYEVLWLPGMDH MAB_1603|M.abscessus_ATCC_1997 KPGYSIVLPPPNVTGSLHMGHALDHTLMDALTRRKRMQGYEVLWLPGMDH Rv2448c|M.tuberculosis_H37Rv KPAYSIVLPPPNVTGSLHMGHALEHTMMDALTRRKRMQGYEVLWQPGTDH Mb2475c|M.bovis_AF2122/97 KPAYSIVLPPPNVTGSLHMGHALEHTMMDALTRRKRMQGYEVLWQPGTDH MMAR_3772|M.marinum_M KPPYSIVLPPPNVTGSLHMGHALEHTMMDALTRRKRMQGYEVLWQPGMDH MUL_3719|M.ulcerans_Agy99 KPPYSIVLPPPNVTGSLHMGHALEHTMMDALTRRKRMQGYEVLWQPGMDH MLBr_01472|M.leprae_Br4923 KPGYSIVLPPPNVTGSLHMGHALEHTMMDALTRRKRMQGYEVLWQPGMDH MAV_1724|M.avium_104 KPGYSIVLPPPNVTGSLHMGHALEHTMMDALTRRKRMQGYEVLWQPGMDH ** ********************:**:**.************** ** ** Mflv_2630|M.gilvum_PYR-GCK AGIATQSVVEKQLAADGKTKEDFGRELFIDKVWDWKRESGGTIGAQMRRI Mvan_3951|M.vanbaalenii_PYR-1 AGIATQTVVEKQLSADGKTKEDFGRELFIDKVWDWKRESGGTIGGQMRRL MSMEG_4630|M.smegmatis_MC2_155 AGIATQTVVEKQLAADGKTKEDLGREEFVAKVWDWKRESGGTIGGQMRRL TH_0609|M.thermoresistible__bu AGIATQTVVEKQLAAQGIRKEDLGREKFIEKVWEWKRQSGGTIGAQMRRL MAB_1603|M.abscessus_ATCC_1997 AGIATQSVVEKQLAADGKTKEDFGRELFIEKVWDWKRESGGTIGGQMRRL Rv2448c|M.tuberculosis_H37Rv AGIATQSVVEQQLAVDGKTKEDLGRELFVDKVWDWKRESGGAIGGQMRRL Mb2475c|M.bovis_AF2122/97 AGIATQSVVEQQLAVDGKTKEDLGRELFVDKVWDWKRESGGAIGGQMRRL MMAR_3772|M.marinum_M AGIATQTVVEKQLAADGKTKEDFGRELFVDKVWDWKRESGGAIGGQMRRL MUL_3719|M.ulcerans_Agy99 AGIATQTVVEKQLAADGKTKEDFGRELFVDKVWDWKRESGGAIGGQMRRL MLBr_01472|M.leprae_Br4923 AGIATQSVVEKQLAINGKIKEDFGRELFVDKVWDWKRESGGAIAGQMRRL MAV_1724|M.avium_104 AGIATQSVVEKQLAVDGKTKEDFGRELFIEKVWDWKRESGGAIGGQMRRL ******:***:**: :* ***:*** *: ***:***:***:*..****: Mflv_2630|M.gilvum_PYR-GCK GDGVDWSRDRFTMDDTLSRAVRTIFKRLFDAGLIYQAERLVNWSPVLETA Mvan_3951|M.vanbaalenii_PYR-1 GDGVDWSRDRFTMDEGLSRAVRTIFKRLFDAGLIYQAERLVNWSPVLETA MSMEG_4630|M.smegmatis_MC2_155 GDGVDWSRDRFTMDEGLSRAVRTIFKRLFDAGLIYQAERLVNWSPVLETA TH_0609|M.thermoresistible__bu GDGVDWSRDRFTMDEGLSRAVRTIFKQLYDAGLIYQAERLVNWSPVLQTA MAB_1603|M.abscessus_ATCC_1997 GDGVDWSRDRFTMDEGLSRAVRTIFKKLFDAGLIYRAERLVNWSPELKTA Rv2448c|M.tuberculosis_H37Rv GDGVDWSRDRFTMDEGLSRAVRTIFKRLYDAGLIYRAERLVNWSPVLQTA Mb2475c|M.bovis_AF2122/97 GDGVDWSRDRFTMDEGLSRAVRTIFKRLYDAGLIYRAERLVNWSPVLQTA MMAR_3772|M.marinum_M GDGVDWSRDRFTMDEGLSRAVRTIFKRLYDAGLIYQAERLVNWSPVLQTA MUL_3719|M.ulcerans_Agy99 GDGVDWSRDRFTMDEGLSRAVRTIFKRLYDAGLIYQAERLVNWSPVLQTA MLBr_01472|M.leprae_Br4923 GDGVDWSRDRFTMDDGLSRAVRMIFKRLYDAGLIYRAERLVNWSPVLRTA MAV_1724|M.avium_104 GDGVDWSRDRFTMDEGLSRAVRTIFKRLYDAGLIYRAERLVNWSPVLQTA **************: ****** ***:*:******:********* *.** Mflv_2630|M.gilvum_PYR-GCK ISDLEVKYEDVEGELVSFRYGSMDDSEPHIVVATTRLETMLADTAIAVHP Mvan_3951|M.vanbaalenii_PYR-1 ISDLEVKYEDVEGELVSFRYGSMEDSEPHIVVATTRLETMLGDTAIAVHP MSMEG_4630|M.smegmatis_MC2_155 ISDLEVKYEDVEGELVSFRYGSMNDDEPHIVVATTRVETMLGDTAIAVHP TH_0609|M.thermoresistible__bu ISDLEVKYEDVEGELVSFRYGSMSDDEPHIVVATTRLETMLGDTAIAVHP MAB_1603|M.abscessus_ATCC_1997 ISDLEVKYEEVEGELVSFRYGSLNDNEPHLVVATTRLETMLGDTAIAVHP Rv2448c|M.tuberculosis_H37Rv ISDLEVNYRDVEGELVSFRYGSLDDSQPHIVVATTRVETMLGDTAIAVHP Mb2475c|M.bovis_AF2122/97 ISDLEVNYRDVEGELVSFRYGSLDDSQPHIVVATTRVETMLGDTAIAVHP MMAR_3772|M.marinum_M ISDLEVNYLEVEGELVSFRYGSLEDSQPHIVVATTRVETMLGDTAIAVHP MUL_3719|M.ulcerans_Agy99 ISDLEVNYLEVEGELVSFRYGSLEDSQPHIVVATTRVETMLGDTAIAVHP MLBr_01472|M.leprae_Br4923 LSDIEVIYDEIEGELISFRYGSLDDDEPHIVVATTRVETMLGDTGIAVHP MAV_1724|M.avium_104 LSDIEVNYEEVEGELVSFRYGSLDDSGPHIVVATTRVETMLGDTAIAVHP :**:** * ::****:******:.*. **:******:****.**.***** Mflv_2630|M.gilvum_PYR-GCK EDDRYRELVGTTLPHPFLDTELIVVADSHVDPEFGTGAVKVTPAHDPNDF Mvan_3951|M.vanbaalenii_PYR-1 DDERYRHLVGTTLPHPFIDRQIVIVADHHVDPEFGTGAVKVTPAHDPNDF MSMEG_4630|M.smegmatis_MC2_155 DDERYRHLVGKTLPHPFVDRDMVIVADTHVDPEFGTGAVKVTPAHDPNDF TH_0609|M.thermoresistible__bu EDERYKHLVGKTLPHPFLDRELVIVADEHVDPEFGSGAVKVTPAHDPNDF MAB_1603|M.abscessus_ATCC_1997 DDERYRHLIGTELAHPFQDRSIPIVADNHVDPEFGTGAVKVTPAHDPNDF Rv2448c|M.tuberculosis_H37Rv DDERYRHLVGTSLAHPFVDRELAIVADEHVDPEFGTGAVKVTPAHDPNDF Mb2475c|M.bovis_AF2122/97 DDERYRHLVGTSLAHPFVDRELAIVADEHVDPEFGTGAVKVTPAHDPNDF MMAR_3772|M.marinum_M DDERYRHLVGTTLAHPFVDRQLIIVADGHVDPEFGTGAVKVTPAHDPNDF MUL_3719|M.ulcerans_Agy99 DDERYRHLVGTTLAHPFVDRQLIIVADGHVDPEFGTGAVKVTPAHDPNDF MLBr_01472|M.leprae_Br4923 DDKRYQHLVGTTLPHPFIDRELVIVADEHVDPEFGTGAVKVTPAHDPNDF MAV_1724|M.avium_104 DDERYRHLVGSSLPHPFVDRQLLIVADEHVDPEFGTGAVKVTPAHDPNDF :*.**:.*:*. *.*** * .: :*** *******:************** Mflv_2630|M.gilvum_PYR-GCK EIGLRHQLPMPTMLETRGRVAGTGTQFDGMDRFEARVAVREALAEQGRIV Mvan_3951|M.vanbaalenii_PYR-1 EIGLRHQLPMPSIMDTKGRIADTRTQFDGLDRFEARFAVRQALADEGRIV MSMEG_4630|M.smegmatis_MC2_155 EIGMRHGLPMPTIMDTKGRIADTGTQFDGMDRFEARVKVREALAAQGRIV TH_0609|M.thermoresistible__bu EIGMRHGLPMITIMDTRGRIADTGTQFDGMDRFEARVKVREALAEQGRIV MAB_1603|M.abscessus_ATCC_1997 EIGLRHNLPMPTIMDVHGRICDSGTQFDGMDRFEARVKVREALAEQGRIV Rv2448c|M.tuberculosis_H37Rv EIGVRHQLPMPSILDTKGRIVDTGTRFDGMDRFEARVAVRQALAAQGRVV Mb2475c|M.bovis_AF2122/97 EIGVRHQLPMPSILDTKGRIVDTGTRFDGMDRFEARVAVRQALAAQGRVV MMAR_3772|M.marinum_M EIGMRHQLPMPSILDTKGRIVDTGTQFDGMDRFEARVAVREALAAQGRVV MUL_3719|M.ulcerans_Agy99 EIGMRHQLPMPSILDTKGRIVDTGTQFDGMDRFEARVAVREALAAQGRVV MLBr_01472|M.leprae_Br4923 EIGLRHNLPMPNVMDVKAVIVDTGTEFDGMDRFEARIAVREALAVQGRIV MAV_1724|M.avium_104 EIGLRHQLPMISIMDTKGRIADTGTQFDGMDRFAARVAVREALAAQGRIV ***:** *** .:::.:. : .: *.***:*** **. **:*** :**:* Mflv_2630|M.gilvum_PYR-GCK AEKRPYLHSVGHSERSGEPIEPRLSLQWWVRVETLAKAAGDAVRNGDTVI Mvan_3951|M.vanbaalenii_PYR-1 EEKRPYLHSVGHSERSGEPIEPRLSLQWWVKVESLAKAAGDAVRNGRTVI MSMEG_4630|M.smegmatis_MC2_155 AEKRPYLHSVGHSERSGEPIEPRLSLQWWVKVESLAKAAGDAVRNGDTVI TH_0609|M.thermoresistible__bu AEKRPYVHSVGHSERSGEPIEPRLSLQWWVKVADLAKAAGDAVRNGETVI MAB_1603|M.abscessus_ATCC_1997 AEKRPYLHSVGHSERSGEPIEPRLSMQWWVKVESLARKAGDAVRSGDTVI Rv2448c|M.tuberculosis_H37Rv EEKRPYLHSVGHSERSGEPIEPRLSLQWWVRVESLAKAAGDAVRNGDTVI Mb2475c|M.bovis_AF2122/97 EEKRPYLHSVGHSERSGEPIEPRLSLQWWVRVESLAKAAGDAVRNGDTVI MMAR_3772|M.marinum_M EEKRPYLHSVGHSDRSGEPIEPRLSLQWWVRVESLAKAAGDAVRNGDTVI MUL_3719|M.ulcerans_Agy99 EEKRPYLHSVGHSDRSGEPFEPRLSLQWWVRVESLAKAAGDAVRNGDTVI MLBr_01472|M.leprae_Br4923 EEKRPYRHSVGHSERSGEVIEPRLSLQWWVRVESLAKAAGDAVRNGDTVI MAV_1724|M.avium_104 EEKRPYLHSVGHSERSGEPIEPRLSLQWWVRVESLAKAAGDAVRNGDTVI ***** ******:**** :*****:****:* **: ******.* *** Mflv_2630|M.gilvum_PYR-GCK HPASLEPRWFAWVDNMHDWCISRQLWWGHRIPIWHGPNGETVCVGPDETP Mvan_3951|M.vanbaalenii_PYR-1 HPASLEPRWFGWVDNMHDWCISRQLWWGHRIPIWHGPNGETVCVGPDETP MSMEG_4630|M.smegmatis_MC2_155 HPPSLEPRWFAWVDNMHDWCISRQLWWGHRIPIWHGPDGETVCVGPDETP TH_0609|M.thermoresistible__bu HPKSLEPRWFAWVDDMHDWCISRQLWWGHRIPIWHGPNGEKVCVGPDETP MAB_1603|M.abscessus_ATCC_1997 HPASLEPRWFAWVDDMHDWCISRQLWWGHRIPIWHGPGGEIVCLGPDEAA Rv2448c|M.tuberculosis_H37Rv HPASMEPRWFSWVDDMHDWCISRQLWWGHRIPIWYGPDGEQVCVGPDETP Mb2475c|M.bovis_AF2122/97 HPASMEPRWFSWVDDMHDWCISRQLWWGHRIPIWYGPDGEQVCVGPDETP MMAR_3772|M.marinum_M HPASLEPRWFAWVDDMHDWCISRQLWWGHRIPIWYGPNGEKVCVGPDETP MUL_3719|M.ulcerans_Agy99 HPASLEPRWFAWVDDMHDWCISRQLWWGHRIPIWYGPDGEKVCVGPDETP MLBr_01472|M.leprae_Br4923 HPASMESRWFAWVDDMRDWCISRQLWWGHRIPIWYGPNGEQVCVGPDETP MAV_1724|M.avium_104 HPTSMEPRWFAWVDDMHDWCISRQLWWGHRIPIWYGPNGEQRCVGPDETP ** *:*.***.***:*:*****************:**.** *:****:. Mflv_2630|M.gilvum_PYR-GCK PEGWEQDPDVLDTWFSSALWPFSTMGWPDHTPELAKFYPTTVLVTGYDIL Mvan_3951|M.vanbaalenii_PYR-1 PEGWEQDPDVLDTWFSSALWPFSTMGWPDHTAELAKFYPTTVLVTGYDIL MSMEG_4630|M.smegmatis_MC2_155 PEGWEQDPDVLDTWFSSALWPFSTMGWPDHTPELAKFYPTSVLVTGYDIL TH_0609|M.thermoresistible__bu PEGWEQDPDVLDTWFSSALWPFSTMGWPDHTPELAKFYPTDVLVTGYDIL MAB_1603|M.abscessus_ATCC_1997 PEGYEQDPDVLDTWFSSALWPFSTMGWPEATPELEKFYPTSVLVTGYDIL Rv2448c|M.tuberculosis_H37Rv PQGWEQDPDVLDTWFSSALWPFSTLGWPDKTAELEKFYPTSVLVTGYDIL Mb2475c|M.bovis_AF2122/97 PQGWEQDPDVLDTWFSSALWPFSTLGWPDKTAELEKFYPTSVLVTGYDIL MMAR_3772|M.marinum_M PQGWEQDSDVLDTWFSSALWPFSTLGWPELTPELEKFYPTSVLVTGYDIL MUL_3719|M.ulcerans_Agy99 PQGWEQDSDVLDTWFSSALWPFSTLGWPELTPELEKFYPTSVLVTGYDIL MLBr_01472|M.leprae_Br4923 PEGWQQDPDVLDTWFSSALWPFSTLGWPQMTPELEKFYPTSILVTGYDIL MAV_1724|M.avium_104 PEGWEQDPDVLDTWFSSALWPFSTLGWPEKTPELEKFYPTSVLVTGYDIL *:*::**.****************:***: *.** ***** :******** Mflv_2630|M.gilvum_PYR-GCK FFWVARMMMFGTFVGGDPAIIGDGAAKKSSPQVPFKNVFLHGLIRDEFGR Mvan_3951|M.vanbaalenii_PYR-1 FFWVARMMMFGTFVGDDPAITGGGAR---GPQVPFENVFLHGLIRDEHGR MSMEG_4630|M.smegmatis_MC2_155 FFWVARMMMFGTFVGDDPAVTLEGAR---GRQVPFENVFLHGLIRDEFGR TH_0609|M.thermoresistible__bu FFWVARMMMFGTFVGDHPAITLDGAR---GPQVPFRNVFLHGLIRDKHGR MAB_1603|M.abscessus_ATCC_1997 FFWVARMMMFGTFVADGPALH--------GGKVPFDNVFLHGLIRDQFGQ Rv2448c|M.tuberculosis_H37Rv FFWVARMMMFGTFVGDDAAITLDGRR---GPQVPFTDVFLHGLIRDESGR Mb2475c|M.bovis_AF2122/97 FFWVARMMMFGTFVGDDAAITLDGRR---GPQVPFTDVFLHGLIRDESGR MMAR_3772|M.marinum_M FFWVARMMMFGTFVGGDEVITLDGRR---GAQVPFTDVFLHGLIRDEFGR MUL_3719|M.ulcerans_Agy99 FFWVARMMMFGTFVGGDEVITLDGRR---GAQVPFTDVFLHGLIRDEFGR MLBr_01472|M.leprae_Br4923 FFWVARMMMLGTFVGGDDAITLGGCR---GPQVPFTDVFLHGLIRDEFGR MAV_1724|M.avium_104 FFWVARMMMFGTFVGDDDAITLDGRR---GPQVPFTDVFLHGLIRDESGR *********:****.. .: . :*** :*********: *: Mflv_2630|M.gilvum_PYR-GCK KMSKSRGNGIDPLDWVETFGADALRFTLARGASPGGDLAIGEDHARASRN Mvan_3951|M.vanbaalenii_PYR-1 KMSKSRGNGIDPLDWVEMFGADALRFTLARGASPGGDLAIGEDHARASRN MSMEG_4630|M.smegmatis_MC2_155 KMSKSRGNGIDPLDWVEKFGADALRFTLARGASPGGDLSIGEDHARASRN TH_0609|M.thermoresistible__bu KMSKSAGNGIDPLDWVQTYGADALRFTLARGASPGSDLSIGDDHARASRN MAB_1603|M.abscessus_ATCC_1997 KMSKSKGNGIDPLDWVEMFGADALRFTLARGASPGGDLSIGEDAARASRN Rv2448c|M.tuberculosis_H37Rv KMSKSKGNVIDPLDWVEMFGADALRFTLARGASPGGDLAVSEDAVRASRN Mb2475c|M.bovis_AF2122/97 KMSKSKGNVIDPLDWVEMFGADALRFTLARGASPGGDLAVSEDAVRASRN MMAR_3772|M.marinum_M KMSKSKGNVIDPLDWIDTFGADALRFTLARGASPGSDLAVGEDAVRASRN MUL_3719|M.ulcerans_Agy99 KMSKSKGNVIDPLDWIDTFGADALRFTLARGASPGSDLAVGEDAVRASRN MLBr_01472|M.leprae_Br4923 KMSKSRGNVIDPLAWMDMFGADALRFTLARGSSPGGDLAIGEDHVRASRN MAV_1724|M.avium_104 KMSKSKGNVIDPLDWVDMFGADALRFTLARGASPGGDLAIGEDHVRASRN ***** ** **** *:: :************:***.**::.:* .***** Mflv_2630|M.gilvum_PYR-GCK FATKLFNATRFALLNGASPAPLPPTAELTDADRWILGRLEEVRADVDAAL Mvan_3951|M.vanbaalenii_PYR-1 FATKLFNATRFALLNGASPAPLPPSDQLTDADRWILGRLEEVRIEVDAAL MSMEG_4630|M.smegmatis_MC2_155 FATKLFNATRFALMNGAAPAPLPAASELTDADRWILGRLEEVRAEVDSAF TH_0609|M.thermoresistible__bu FVTKLFNATRFALLNGAAPAPLPDAAELTDADRWILGRLEEVRTEVDSAF MAB_1603|M.abscessus_ATCC_1997 FTTKLFNATRFALMNGAALGELPDVAELTDADRWILGRLEQVRAEVDGAL Rv2448c|M.tuberculosis_H37Rv FGTKLFNATRYALLNGAAPAPLPSPNELTDADRWILGRLEEVRAEVDSAF Mb2475c|M.bovis_AF2122/97 FGTKLFNATRYALLNGAAPAPLPSPNELTDADRWILGRLEEVRAEVDSAF MMAR_3772|M.marinum_M FGTKLFNATRYALLNGAALAPLPPLGELTDADRWILGRLEEVRAEVDSAF MUL_3719|M.ulcerans_Agy99 FGTKLFNATRYALLNGAALAPLPPLGELTDADRWILGRLEEVRAEVDSAF MLBr_01472|M.leprae_Br4923 FGTKLFNATRYALLNGAALVPLPALTALTDADRWILGRLEQVRAEVDSAF MAV_1724|M.avium_104 FCTKLFNATRYALLNGAQLAQLPPLDELTDADRWILGRLEEVRAEVDSAF * ********:**:*** ** *************:** :**.*: Mflv_2630|M.gilvum_PYR-GCK DNYEFNRACEALYHFAWDEFCDWYLELAKVQLGQEDPQTARTTAVLATVL Mvan_3951|M.vanbaalenii_PYR-1 DNYEFSRACESLYHFAWDEFCDWYLELAKVQLGQEEAHTARTTAVLAFAL MSMEG_4630|M.smegmatis_MC2_155 DNYEFNRACEALYHFAWDEFCDWYVELAKVQLGQEEVHTARTTAVLAAVL TH_0609|M.thermoresistible__bu DSYEFSRACETLYHFAWDEFCDWYVELAKVQLSEG---ISHTTAVLAAVL MAB_1603|M.abscessus_ATCC_1997 DRYEFSVACEGLYHFAWDEFCDWYLELAKVQMVDR---AESTRVVLATVL Rv2448c|M.tuberculosis_H37Rv DGYEFSRACESLYHFAWDEFCDWYLELAKTQLAQG---LTHTTAVLAAGL Mb2475c|M.bovis_AF2122/97 DGYEFSRACESLYHFAWDEFCDWYLELAKTQLAQG---LTHTTAVLAAGL MMAR_3772|M.marinum_M DSYEFSRACEALYHFAWDEFCDWYVELAKTQLAEG---LSATTAVLAAGL MUL_3719|M.ulcerans_Agy99 DSYEFSRACEALYHFAWDEFCDWYVELAKTQLAEG---LSATTAVLAAGL MLBr_01472|M.leprae_Br4923 DGYEFSRACEALYHFAWDEFCDWYLELAKAQLADG---LTHTTAVLAAAL MAV_1724|M.avium_104 DNYEFSRACESLYHFAWDEFCDWYVELAKTQLAEG---ITHTTAVLATTL * ***. *** *************:****.*: : * .*** * Mflv_2630|M.gilvum_PYR-GCK DVLLKLLHPVMPFVTEVLWKTLTGGESLVIADWPTATGFASDHAAAQRIT Mvan_3951|M.vanbaalenii_PYR-1 DVLLKLLHPVMPFVTEVLWKALTGGESLVIADWPTATGYAVDQGATQRVA MSMEG_4630|M.smegmatis_MC2_155 DTLLKLLHPVMPFVTETLWKTLTGGESVVVATWPEPSGFAPDTVATQRIT TH_0609|M.thermoresistible__bu DTLLKLLHPVMPFVTEKLWKTLTDGESLVIAKWPQPSGFSLDSIAAQRVA MAB_1603|M.abscessus_ATCC_1997 DTLLRLLHPVIPFVTEVLWKSVTGGESVVIAAWPTGSGIELDGTAAQRIA Rv2448c|M.tuberculosis_H37Rv DTLLRLLHPVIPFLTEALWLALTGRESLVSADWPEPSGISVDLVAAQRIN Mb2475c|M.bovis_AF2122/97 DTLLRLLHPVIPFLTEALWLALTGRESLVSADWPEPSGISVDLVAAQRIN MMAR_3772|M.marinum_M DTLLRLLHPVIPFITEALWQALTGQESLVIADWPQPSGITLDPVAAQRIS MUL_3719|M.ulcerans_Agy99 DTLLRLLHPVIPFITEALWQALTGQESLVIADWPQPSGITLDPVAAQRIS MLBr_01472|M.leprae_Br4923 DTLLRLLHPVMPFITETLWQALTQLESLVIATWPEPSGISLDLVAAQRIS MAV_1724|M.avium_104 DTLLRLLHPVIPFITEALWQALTGNESLVIADWPRSSGVGLDQVATQRIT *.**:*****:**:** ** ::* **:* * ** :* * *:**: Mflv_2630|M.gilvum_PYR-GCK DMQKLITEVRRFRSDQGLADRQKVPARLSEVSAAGLDAHVPAVTALAWLT Mvan_3951|M.vanbaalenii_PYR-1 DMQKLITEVRRFRSDQGLADRQKVPARLSDVAAAGLEEHVPAVTALAWLT MSMEG_4630|M.smegmatis_MC2_155 DMQKLITEVRRFRSDQGLADRQKVPARLTDVEAAGLTAQLPAVAALAWLT TH_0609|M.thermoresistible__bu DMQRLITEVRRFRSDQGLADRQKVPARLSDIPGADLQAQLPAIRALAWLT MAB_1603|M.abscessus_ATCC_1997 DMQKLVTEVRRFRSDQGLGDRQKVAARLSGVGEAGLDDQLAAVTSLAWLT Rv2448c|M.tuberculosis_H37Rv DMQKLVTEVRRFRSDQGLADRQKVPARMHGVRDSDLSNQVAAVTSLAWLT Mb2475c|M.bovis_AF2122/97 DMQKLVTEVRRFRSDQGLADRQKVPARMHGVRDSDLSNQVAAVTSLAWLT MMAR_3772|M.marinum_M DMQNLVTEIRRFRSDQGLADRQKVPARLIGVEESDLGAQVAAVTSLAWLT MUL_3719|M.ulcerans_Agy99 DMQNLVTEIRRFRSDQGLADRQKVPARLIGVEESDLGAQVAAVTSLAWLT MLBr_01472|M.leprae_Br4923 DMQKLVTEIRRFRSDQGLVDRQKVPARLSGVEDSDLATQVGFVTSLALLT MAV_1724|M.avium_104 DMQKLVTEVRRFRSDQGLADRQKVPARLAGVTESDLDTQVSAVTSLAWLT ***.*:**:********* *****.**: : :.* :: : :** ** Mflv_2630|M.gilvum_PYR-GCK PPAEGFTPSASVEVRLSAS---TVVVEVDTSGTVDVDAERRRLEKDLAAA Mvan_3951|M.vanbaalenii_PYR-1 PPADEFTPSAAVEVRLSTA---TVVVEVDTSGTVDVAAERRRLEKDLAAA MSMEG_4630|M.smegmatis_MC2_155 EAGDGFSPSASVEVRLSQG---TVVVEVDTSGTVDVEAERRRLEKDLGGR TH_0609|M.thermoresistible__bu DAGADFNPSAALEVRLSKG---TVVVELDTRGSVDVEAERRRTEKDLAAA MAB_1603|M.abscessus_ATCC_1997 PAEEGFSPTASVEVRLSGA---TVTVEVDTSGTVDVEAERRRLEKDLAAA Rv2448c|M.tuberculosis_H37Rv EPGPDFEPSVSLEVRLGPEMNRTVVVELDTSGTIDVAAERRRLEKELAGA Mb2475c|M.bovis_AF2122/97 EPGPDFEPSVSLEVRLGPEMNRTVVVELDTSGTIDVAAERRRLEKELAGA MMAR_3772|M.marinum_M APGEGFAPSVSLEVRLGPSMNHTVVVELDTSGTIDVAAERRRLEKDLAAA MUL_3719|M.ulcerans_Agy99 APGEGFAPSVSLEVRLGPSMNHTVVVELDTSGTIDVAAERRRLEKDLAAA MLBr_01472|M.leprae_Br4923 AASNDFRPSALLEVRLGPNKDRAVVVELDTSGTIDVAAERRRMEKDLAAA MAV_1724|M.avium_104 DAGPDFRPSASVEVRLRGG---TVVVELDTSGSIDVAAERRRLEKDLAAA . * *:. :**** :*.**:** *::** ***** **:*.. Mflv_2630|M.gilvum_PYR-GCK QKELAGTSAKLGNDAFLAKAPADVVDKIRARRQVAGEEVDRITARLSALP Mvan_3951|M.vanbaalenii_PYR-1 QKELSGTSGKLGNEAFLAKAPADVVDKIRARQQVANEEVERIQARLAALS MSMEG_4630|M.smegmatis_MC2_155 PEGTGHHHGQTRQRGLPVQG-----ARPGGRQDPGQASPGQ--------- TH_0609|M.thermoresistible__bu RRELESTSKKLENEAFLAKAPAEVVEKIRNRQRLAAEEVDRLTARLAALK MAB_1603|M.abscessus_ATCC_1997 RKELDGTTSKLGNDAFLAKAPEAVVEKIRVRQQVATEEVERITARLAALA Rv2448c|M.tuberculosis_H37Rv QKELASTAAKLANADFLAKAPDAVIAKIRDRQRVAQQETERITTRLAALQ Mb2475c|M.bovis_AF2122/97 QKELASTAAKLANADFLAKAPDAVIAKIRDRQRVAQQETERITTRLAALQ MMAR_3772|M.marinum_M EKELVSTAAKLANADFLAKAPEAVVGKIRDRQRLAQEESDRITTRLAALQ MUL_3719|M.ulcerans_Agy99 EKELVSAAAKLANADFLAKAPEAVVGKIRDRQRLAQEESDRITTRLAALQ MLBr_01472|M.leprae_Br4923 QKELASTAAKLANADFLAKAPEAVVVKIRDRQRMAKEETDRIIARLAGLQ MAV_1724|M.avium_104 HKELASTTAKLANEDFLAKAPPHVVDKIRDRQRLAQEESERINARLAVLQ . : : : .:. : *: . . : Mflv_2630|M.gilvum_PYR-GCK AGE Mvan_3951|M.vanbaalenii_PYR-1 ASE MSMEG_4630|M.smegmatis_MC2_155 --- TH_0609|M.thermoresistible__bu DS- MAB_1603|M.abscessus_ATCC_1997 --- Rv2448c|M.tuberculosis_H37Rv --- Mb2475c|M.bovis_AF2122/97 --- MMAR_3772|M.marinum_M --- MUL_3719|M.ulcerans_Agy99 --- MLBr_01472|M.leprae_Br4923 --- MAV_1724|M.avium_104 ---