For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TASADSAADQLPKSWDPAAMEGDIYQKWADAGYFVADPTSSKPPYSIVLPPPNVTGSLHMGHALEHTMMD ALTRRKRMQGYEVLWQPGMDHAGIATQTVVEKQLAADGKTKEDFGRELFVDKVWDWKRESGGAIGGQMRR LGDGVDWSRDRFTMDEGLSRAVRTIFKRLYDAGLIYQAERLVNWSPVLQTAISDLEVNYLEVEGELVSFR YGSLEDSQPHIVVATTRVETMLGDTAIAVHPDDERYRHLVGTTLAHPFVDRQLIIVADGHVDPEFGTGAV KVTPAHDPNDFEIGMRHQLPMPSILDTKGRIVDTGTQFDGMDRFEARVAVREALAAQGRVVEEKRPYLHS VGHSDRSGEPIEPRLSLQWWVRVESLAKAAGDAVRNGDTVIHPASLEPRWFAWVDDMHDWCISRQLWWGH RIPIWYGPNGEKVCVGPDETPPQGWEQDSDVLDTWFSSALWPFSTLGWPELTPELEKFYPTSVLVTGYDI LFFWVARMMMFGTFVGGDEVITLDGRRGAQVPFTDVFLHGLIRDEFGRKMSKSKGNVIDPLDWIDTFGAD ALRFTLARGASPGSDLAVGEDAVRASRNFGTKLFNATRYALLNGAALAPLPPLGELTDADRWILGRLEEV RAEVDSAFDSYEFSRACEALYHFAWDEFCDWYVELAKTQLAEGLSATTAVLAAGLDTLLRLLHPVIPFIT EALWQALTGQESLVIADWPQPSGITLDPVAAQRISDMQNLVTEIRRFRSDQGLADRQKVPARLIGVEESD LGAQVAAVTSLAWLTAPGEGFAPSVSLEVRLGPSMNHTVVVELDTSGTIDVAAERRRLEKDLAAAEKELV STAAKLANADFLAKAPEAVVGKIRDRQRLAQEESDRITTRLAALQ*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_3772 | valS | - | 100% (886) | valyl-tRNA synthetase protein ValS |
M. marinum M | MMAR_2356 | ileS | 4e-48 | 24.05% (873) | isoleucyl-tRNA synthetase IleS |
M. marinum M | MMAR_4481 | metS | 5e-13 | 29.44% (214) | methionyl-tRNA synthetase MetS |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2475c | valS | 0.0 | 90.29% (875) | valyl-tRNA synthetase |
M. gilvum PYR-GCK | Mflv_2630 | valS | 0.0 | 80.50% (882) | valyl-tRNA synthetase |
M. tuberculosis H37Rv | Rv2448c | valS | 0.0 | 90.29% (875) | valyl-tRNA synthetase |
M. leprae Br4923 | MLBr_01472 | valS | 0.0 | 85.21% (886) | valyl-tRNA synthetase |
M. abscessus ATCC 19977 | MAB_1603 | valS | 0.0 | 79.12% (886) | valyl-tRNA synthetase |
M. avium 104 | MAV_1724 | valS | 0.0 | 88.04% (886) | valyl-tRNA synthetase |
M. smegmatis MC2 155 | MSMEG_4630 | valS | 0.0 | 83.01% (836) | valyl-tRNA synthetase |
M. thermoresistible (build 8) | TH_0609 | valS | 0.0 | 80.73% (877) | PROBABLE VALYL-tRNA SYNTHASE PROTEIN VALS (VALYL-tRNA |
M. ulcerans Agy99 | MUL_3719 | valS | 0.0 | 99.66% (886) | valyl-tRNA synthetase |
M. vanbaalenii PYR-1 | Mvan_3951 | valS | 0.0 | 81.00% (879) | valyl-tRNA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2630|M.gilvum_PYR-GCK MTSQPHANGDARSVPELDALPKSWDPGTVESDLYDGWVEAGYFTADPSSD Mvan_3951|M.vanbaalenii_PYR-1 MTSQPTANGDAPRAPELDALPKSWDPGAVESDLYDGWVKAGYFTADPTSA MSMEG_4630|M.smegmatis_MC2_155 MTASPENR--------ADALPKSWDPGAVEAELYQGWVDAGYFTADPASD TH_0609|M.thermoresistible__bu ----------------VESLPKTWDPAAVETELYEGWVRAGYFTADPSSS MAB_1603|M.abscessus_ATCC_1997 MTQTPDTN-------AASSLPTSWDPGAVEAELYQGWVDAGYFTADPSSD MMAR_3772|M.marinum_M MTASADSA--------ADQLPKSWDPAAMEGDIYQKWADAGYFVADPTSS MUL_3719|M.ulcerans_Agy99 MTASADSA--------ADQLPKSWDPAAMEGDIYQKWADAGYFVADPTSS Mb2475c|M.bovis_AF2122/97 ------------------MLPKSWDPAAMESAIYQKWLDAGYFTADPTST Rv2448c|M.tuberculosis_H37Rv ------------------MLPKSWDPAAMESAIYQKWLDAGYFTADPTST MLBr_01472|M.leprae_Br4923 MTTSPSSS--------ADLLPKSWDPGAMESVIYQKWLNSGYFAADPAST MAV_1724|M.avium_104 MTAS-RSP--------ATDLPKSWDPAAAEYAIYRQWVDAGYFTANPASD **.:***.: * :* * :***.*:*:* Mflv_2630|M.gilvum_PYR-GCK KPAYSIVLPPPNVTGSLHMGHALDHTLMDALTRRKRMQGYEVLWLPGMDH Mvan_3951|M.vanbaalenii_PYR-1 KPAYSIVLPPPNVTGSLHMGHALDHTLMDALTRRKRMQGYEVLWLPGMDH MSMEG_4630|M.smegmatis_MC2_155 KPPYSIVLPPPNVTGSLHMGHALDHTLMDVLTRRKRMQGYEVLWLPGMDH TH_0609|M.thermoresistible__bu KPSYSIVLPPPNVTGSLHMGHALDHTLMDALTRRKRMQGYEVLWLPGMDH MAB_1603|M.abscessus_ATCC_1997 KPGYSIVLPPPNVTGSLHMGHALDHTLMDALTRRKRMQGYEVLWLPGMDH MMAR_3772|M.marinum_M KPPYSIVLPPPNVTGSLHMGHALEHTMMDALTRRKRMQGYEVLWQPGMDH MUL_3719|M.ulcerans_Agy99 KPPYSIVLPPPNVTGSLHMGHALEHTMMDALTRRKRMQGYEVLWQPGMDH Mb2475c|M.bovis_AF2122/97 KPAYSIVLPPPNVTGSLHMGHALEHTMMDALTRRKRMQGYEVLWQPGTDH Rv2448c|M.tuberculosis_H37Rv KPAYSIVLPPPNVTGSLHMGHALEHTMMDALTRRKRMQGYEVLWQPGTDH MLBr_01472|M.leprae_Br4923 KPGYSIVLPPPNVTGSLHMGHALEHTMMDALTRRKRMQGYEVLWQPGMDH MAV_1724|M.avium_104 KPGYSIVLPPPNVTGSLHMGHALEHTMMDALTRRKRMQGYEVLWQPGMDH ** ********************:**:**.************** ** ** Mflv_2630|M.gilvum_PYR-GCK AGIATQSVVEKQLAADGKTKEDFGRELFIDKVWDWKRESGGTIGAQMRRI Mvan_3951|M.vanbaalenii_PYR-1 AGIATQTVVEKQLSADGKTKEDFGRELFIDKVWDWKRESGGTIGGQMRRL MSMEG_4630|M.smegmatis_MC2_155 AGIATQTVVEKQLAADGKTKEDLGREEFVAKVWDWKRESGGTIGGQMRRL TH_0609|M.thermoresistible__bu AGIATQTVVEKQLAAQGIRKEDLGREKFIEKVWEWKRQSGGTIGAQMRRL MAB_1603|M.abscessus_ATCC_1997 AGIATQSVVEKQLAADGKTKEDFGRELFIEKVWDWKRESGGTIGGQMRRL MMAR_3772|M.marinum_M AGIATQTVVEKQLAADGKTKEDFGRELFVDKVWDWKRESGGAIGGQMRRL MUL_3719|M.ulcerans_Agy99 AGIATQTVVEKQLAADGKTKEDFGRELFVDKVWDWKRESGGAIGGQMRRL Mb2475c|M.bovis_AF2122/97 AGIATQSVVEQQLAVDGKTKEDLGRELFVDKVWDWKRESGGAIGGQMRRL Rv2448c|M.tuberculosis_H37Rv AGIATQSVVEQQLAVDGKTKEDLGRELFVDKVWDWKRESGGAIGGQMRRL MLBr_01472|M.leprae_Br4923 AGIATQSVVEKQLAINGKIKEDFGRELFVDKVWDWKRESGGAIAGQMRRL MAV_1724|M.avium_104 AGIATQSVVEKQLAVDGKTKEDFGRELFIEKVWDWKRESGGAIGGQMRRL ******:***:**: :* ***:*** *: ***:***:***:*..****: Mflv_2630|M.gilvum_PYR-GCK GDGVDWSRDRFTMDDTLSRAVRTIFKRLFDAGLIYQAERLVNWSPVLETA Mvan_3951|M.vanbaalenii_PYR-1 GDGVDWSRDRFTMDEGLSRAVRTIFKRLFDAGLIYQAERLVNWSPVLETA MSMEG_4630|M.smegmatis_MC2_155 GDGVDWSRDRFTMDEGLSRAVRTIFKRLFDAGLIYQAERLVNWSPVLETA TH_0609|M.thermoresistible__bu GDGVDWSRDRFTMDEGLSRAVRTIFKQLYDAGLIYQAERLVNWSPVLQTA MAB_1603|M.abscessus_ATCC_1997 GDGVDWSRDRFTMDEGLSRAVRTIFKKLFDAGLIYRAERLVNWSPELKTA MMAR_3772|M.marinum_M GDGVDWSRDRFTMDEGLSRAVRTIFKRLYDAGLIYQAERLVNWSPVLQTA MUL_3719|M.ulcerans_Agy99 GDGVDWSRDRFTMDEGLSRAVRTIFKRLYDAGLIYQAERLVNWSPVLQTA Mb2475c|M.bovis_AF2122/97 GDGVDWSRDRFTMDEGLSRAVRTIFKRLYDAGLIYRAERLVNWSPVLQTA Rv2448c|M.tuberculosis_H37Rv GDGVDWSRDRFTMDEGLSRAVRTIFKRLYDAGLIYRAERLVNWSPVLQTA MLBr_01472|M.leprae_Br4923 GDGVDWSRDRFTMDDGLSRAVRMIFKRLYDAGLIYRAERLVNWSPVLRTA MAV_1724|M.avium_104 GDGVDWSRDRFTMDEGLSRAVRTIFKRLYDAGLIYRAERLVNWSPVLQTA **************: ****** ***:*:******:********* *.** Mflv_2630|M.gilvum_PYR-GCK ISDLEVKYEDVEGELVSFRYGSMDDSEPHIVVATTRLETMLADTAIAVHP Mvan_3951|M.vanbaalenii_PYR-1 ISDLEVKYEDVEGELVSFRYGSMEDSEPHIVVATTRLETMLGDTAIAVHP MSMEG_4630|M.smegmatis_MC2_155 ISDLEVKYEDVEGELVSFRYGSMNDDEPHIVVATTRVETMLGDTAIAVHP TH_0609|M.thermoresistible__bu ISDLEVKYEDVEGELVSFRYGSMSDDEPHIVVATTRLETMLGDTAIAVHP MAB_1603|M.abscessus_ATCC_1997 ISDLEVKYEEVEGELVSFRYGSLNDNEPHLVVATTRLETMLGDTAIAVHP MMAR_3772|M.marinum_M ISDLEVNYLEVEGELVSFRYGSLEDSQPHIVVATTRVETMLGDTAIAVHP MUL_3719|M.ulcerans_Agy99 ISDLEVNYLEVEGELVSFRYGSLEDSQPHIVVATTRVETMLGDTAIAVHP Mb2475c|M.bovis_AF2122/97 ISDLEVNYRDVEGELVSFRYGSLDDSQPHIVVATTRVETMLGDTAIAVHP Rv2448c|M.tuberculosis_H37Rv ISDLEVNYRDVEGELVSFRYGSLDDSQPHIVVATTRVETMLGDTAIAVHP MLBr_01472|M.leprae_Br4923 LSDIEVIYDEIEGELISFRYGSLDDDEPHIVVATTRVETMLGDTGIAVHP MAV_1724|M.avium_104 LSDIEVNYEEVEGELVSFRYGSLDDSGPHIVVATTRVETMLGDTAIAVHP :**:** * ::****:******:.*. **:******:****.**.***** Mflv_2630|M.gilvum_PYR-GCK EDDRYRELVGTTLPHPFLDTELIVVADSHVDPEFGTGAVKVTPAHDPNDF Mvan_3951|M.vanbaalenii_PYR-1 DDERYRHLVGTTLPHPFIDRQIVIVADHHVDPEFGTGAVKVTPAHDPNDF MSMEG_4630|M.smegmatis_MC2_155 DDERYRHLVGKTLPHPFVDRDMVIVADTHVDPEFGTGAVKVTPAHDPNDF TH_0609|M.thermoresistible__bu EDERYKHLVGKTLPHPFLDRELVIVADEHVDPEFGSGAVKVTPAHDPNDF MAB_1603|M.abscessus_ATCC_1997 DDERYRHLIGTELAHPFQDRSIPIVADNHVDPEFGTGAVKVTPAHDPNDF MMAR_3772|M.marinum_M DDERYRHLVGTTLAHPFVDRQLIIVADGHVDPEFGTGAVKVTPAHDPNDF MUL_3719|M.ulcerans_Agy99 DDERYRHLVGTTLAHPFVDRQLIIVADGHVDPEFGTGAVKVTPAHDPNDF Mb2475c|M.bovis_AF2122/97 DDERYRHLVGTSLAHPFVDRELAIVADEHVDPEFGTGAVKVTPAHDPNDF Rv2448c|M.tuberculosis_H37Rv DDERYRHLVGTSLAHPFVDRELAIVADEHVDPEFGTGAVKVTPAHDPNDF MLBr_01472|M.leprae_Br4923 DDKRYQHLVGTTLPHPFIDRELVIVADEHVDPEFGTGAVKVTPAHDPNDF MAV_1724|M.avium_104 DDERYRHLVGSSLPHPFVDRQLLIVADEHVDPEFGTGAVKVTPAHDPNDF :*.**:.*:*. *.*** * .: :*** *******:************** Mflv_2630|M.gilvum_PYR-GCK EIGLRHQLPMPTMLETRGRVAGTGTQFDGMDRFEARVAVREALAEQGRIV Mvan_3951|M.vanbaalenii_PYR-1 EIGLRHQLPMPSIMDTKGRIADTRTQFDGLDRFEARFAVRQALADEGRIV MSMEG_4630|M.smegmatis_MC2_155 EIGMRHGLPMPTIMDTKGRIADTGTQFDGMDRFEARVKVREALAAQGRIV TH_0609|M.thermoresistible__bu EIGMRHGLPMITIMDTRGRIADTGTQFDGMDRFEARVKVREALAEQGRIV MAB_1603|M.abscessus_ATCC_1997 EIGLRHNLPMPTIMDVHGRICDSGTQFDGMDRFEARVKVREALAEQGRIV MMAR_3772|M.marinum_M EIGMRHQLPMPSILDTKGRIVDTGTQFDGMDRFEARVAVREALAAQGRVV MUL_3719|M.ulcerans_Agy99 EIGMRHQLPMPSILDTKGRIVDTGTQFDGMDRFEARVAVREALAAQGRVV Mb2475c|M.bovis_AF2122/97 EIGVRHQLPMPSILDTKGRIVDTGTRFDGMDRFEARVAVRQALAAQGRVV Rv2448c|M.tuberculosis_H37Rv EIGVRHQLPMPSILDTKGRIVDTGTRFDGMDRFEARVAVRQALAAQGRVV MLBr_01472|M.leprae_Br4923 EIGLRHNLPMPNVMDVKAVIVDTGTEFDGMDRFEARIAVREALAVQGRIV MAV_1724|M.avium_104 EIGLRHQLPMISIMDTKGRIADTGTQFDGMDRFAARVAVREALAAQGRIV ***:** *** .:::.:. : .: *.***:*** **. **:*** :**:* Mflv_2630|M.gilvum_PYR-GCK AEKRPYLHSVGHSERSGEPIEPRLSLQWWVRVETLAKAAGDAVRNGDTVI Mvan_3951|M.vanbaalenii_PYR-1 EEKRPYLHSVGHSERSGEPIEPRLSLQWWVKVESLAKAAGDAVRNGRTVI MSMEG_4630|M.smegmatis_MC2_155 AEKRPYLHSVGHSERSGEPIEPRLSLQWWVKVESLAKAAGDAVRNGDTVI TH_0609|M.thermoresistible__bu AEKRPYVHSVGHSERSGEPIEPRLSLQWWVKVADLAKAAGDAVRNGETVI MAB_1603|M.abscessus_ATCC_1997 AEKRPYLHSVGHSERSGEPIEPRLSMQWWVKVESLARKAGDAVRSGDTVI MMAR_3772|M.marinum_M EEKRPYLHSVGHSDRSGEPIEPRLSLQWWVRVESLAKAAGDAVRNGDTVI MUL_3719|M.ulcerans_Agy99 EEKRPYLHSVGHSDRSGEPFEPRLSLQWWVRVESLAKAAGDAVRNGDTVI Mb2475c|M.bovis_AF2122/97 EEKRPYLHSVGHSERSGEPIEPRLSLQWWVRVESLAKAAGDAVRNGDTVI Rv2448c|M.tuberculosis_H37Rv EEKRPYLHSVGHSERSGEPIEPRLSLQWWVRVESLAKAAGDAVRNGDTVI MLBr_01472|M.leprae_Br4923 EEKRPYRHSVGHSERSGEVIEPRLSLQWWVRVESLAKAAGDAVRNGDTVI MAV_1724|M.avium_104 EEKRPYLHSVGHSERSGEPIEPRLSLQWWVRVESLAKAAGDAVRNGDTVI ***** ******:**** :*****:****:* **: ******.* *** Mflv_2630|M.gilvum_PYR-GCK HPASLEPRWFAWVDNMHDWCISRQLWWGHRIPIWHGPNGETVCVGPDETP Mvan_3951|M.vanbaalenii_PYR-1 HPASLEPRWFGWVDNMHDWCISRQLWWGHRIPIWHGPNGETVCVGPDETP MSMEG_4630|M.smegmatis_MC2_155 HPPSLEPRWFAWVDNMHDWCISRQLWWGHRIPIWHGPDGETVCVGPDETP TH_0609|M.thermoresistible__bu HPKSLEPRWFAWVDDMHDWCISRQLWWGHRIPIWHGPNGEKVCVGPDETP MAB_1603|M.abscessus_ATCC_1997 HPASLEPRWFAWVDDMHDWCISRQLWWGHRIPIWHGPGGEIVCLGPDEAA MMAR_3772|M.marinum_M HPASLEPRWFAWVDDMHDWCISRQLWWGHRIPIWYGPNGEKVCVGPDETP MUL_3719|M.ulcerans_Agy99 HPASLEPRWFAWVDDMHDWCISRQLWWGHRIPIWYGPDGEKVCVGPDETP Mb2475c|M.bovis_AF2122/97 HPASMEPRWFSWVDDMHDWCISRQLWWGHRIPIWYGPDGEQVCVGPDETP Rv2448c|M.tuberculosis_H37Rv HPASMEPRWFSWVDDMHDWCISRQLWWGHRIPIWYGPDGEQVCVGPDETP MLBr_01472|M.leprae_Br4923 HPASMESRWFAWVDDMRDWCISRQLWWGHRIPIWYGPNGEQVCVGPDETP MAV_1724|M.avium_104 HPTSMEPRWFAWVDDMHDWCISRQLWWGHRIPIWYGPNGEQRCVGPDETP ** *:*.***.***:*:*****************:**.** *:****:. Mflv_2630|M.gilvum_PYR-GCK PEGWEQDPDVLDTWFSSALWPFSTMGWPDHTPELAKFYPTTVLVTGYDIL Mvan_3951|M.vanbaalenii_PYR-1 PEGWEQDPDVLDTWFSSALWPFSTMGWPDHTAELAKFYPTTVLVTGYDIL MSMEG_4630|M.smegmatis_MC2_155 PEGWEQDPDVLDTWFSSALWPFSTMGWPDHTPELAKFYPTSVLVTGYDIL TH_0609|M.thermoresistible__bu PEGWEQDPDVLDTWFSSALWPFSTMGWPDHTPELAKFYPTDVLVTGYDIL MAB_1603|M.abscessus_ATCC_1997 PEGYEQDPDVLDTWFSSALWPFSTMGWPEATPELEKFYPTSVLVTGYDIL MMAR_3772|M.marinum_M PQGWEQDSDVLDTWFSSALWPFSTLGWPELTPELEKFYPTSVLVTGYDIL MUL_3719|M.ulcerans_Agy99 PQGWEQDSDVLDTWFSSALWPFSTLGWPELTPELEKFYPTSVLVTGYDIL Mb2475c|M.bovis_AF2122/97 PQGWEQDPDVLDTWFSSALWPFSTLGWPDKTAELEKFYPTSVLVTGYDIL Rv2448c|M.tuberculosis_H37Rv PQGWEQDPDVLDTWFSSALWPFSTLGWPDKTAELEKFYPTSVLVTGYDIL MLBr_01472|M.leprae_Br4923 PEGWQQDPDVLDTWFSSALWPFSTLGWPQMTPELEKFYPTSILVTGYDIL MAV_1724|M.avium_104 PEGWEQDPDVLDTWFSSALWPFSTLGWPEKTPELEKFYPTSVLVTGYDIL *:*::**.****************:***: *.** ***** :******** Mflv_2630|M.gilvum_PYR-GCK FFWVARMMMFGTFVGGDPAIIGDGAAKKSSPQVPFKNVFLHGLIRDEFGR Mvan_3951|M.vanbaalenii_PYR-1 FFWVARMMMFGTFVGDDPAITGGGAR---GPQVPFENVFLHGLIRDEHGR MSMEG_4630|M.smegmatis_MC2_155 FFWVARMMMFGTFVGDDPAVTLEGAR---GRQVPFENVFLHGLIRDEFGR TH_0609|M.thermoresistible__bu FFWVARMMMFGTFVGDHPAITLDGAR---GPQVPFRNVFLHGLIRDKHGR MAB_1603|M.abscessus_ATCC_1997 FFWVARMMMFGTFVADGPALH--------GGKVPFDNVFLHGLIRDQFGQ MMAR_3772|M.marinum_M FFWVARMMMFGTFVGGDEVITLDGRR---GAQVPFTDVFLHGLIRDEFGR MUL_3719|M.ulcerans_Agy99 FFWVARMMMFGTFVGGDEVITLDGRR---GAQVPFTDVFLHGLIRDEFGR Mb2475c|M.bovis_AF2122/97 FFWVARMMMFGTFVGDDAAITLDGRR---GPQVPFTDVFLHGLIRDESGR Rv2448c|M.tuberculosis_H37Rv FFWVARMMMFGTFVGDDAAITLDGRR---GPQVPFTDVFLHGLIRDESGR MLBr_01472|M.leprae_Br4923 FFWVARMMMLGTFVGGDDAITLGGCR---GPQVPFTDVFLHGLIRDEFGR MAV_1724|M.avium_104 FFWVARMMMFGTFVGDDDAITLDGRR---GPQVPFTDVFLHGLIRDESGR *********:****.. .: . :*** :*********: *: Mflv_2630|M.gilvum_PYR-GCK KMSKSRGNGIDPLDWVETFGADALRFTLARGASPGGDLAIGEDHARASRN Mvan_3951|M.vanbaalenii_PYR-1 KMSKSRGNGIDPLDWVEMFGADALRFTLARGASPGGDLAIGEDHARASRN MSMEG_4630|M.smegmatis_MC2_155 KMSKSRGNGIDPLDWVEKFGADALRFTLARGASPGGDLSIGEDHARASRN TH_0609|M.thermoresistible__bu KMSKSAGNGIDPLDWVQTYGADALRFTLARGASPGSDLSIGDDHARASRN MAB_1603|M.abscessus_ATCC_1997 KMSKSKGNGIDPLDWVEMFGADALRFTLARGASPGGDLSIGEDAARASRN MMAR_3772|M.marinum_M KMSKSKGNVIDPLDWIDTFGADALRFTLARGASPGSDLAVGEDAVRASRN MUL_3719|M.ulcerans_Agy99 KMSKSKGNVIDPLDWIDTFGADALRFTLARGASPGSDLAVGEDAVRASRN Mb2475c|M.bovis_AF2122/97 KMSKSKGNVIDPLDWVEMFGADALRFTLARGASPGGDLAVSEDAVRASRN Rv2448c|M.tuberculosis_H37Rv KMSKSKGNVIDPLDWVEMFGADALRFTLARGASPGGDLAVSEDAVRASRN MLBr_01472|M.leprae_Br4923 KMSKSRGNVIDPLAWMDMFGADALRFTLARGSSPGGDLAIGEDHVRASRN MAV_1724|M.avium_104 KMSKSKGNVIDPLDWVDMFGADALRFTLARGASPGGDLAIGEDHVRASRN ***** ** **** *:: :************:***.**::.:* .***** Mflv_2630|M.gilvum_PYR-GCK FATKLFNATRFALLNGASPAPLPPTAELTDADRWILGRLEEVRADVDAAL Mvan_3951|M.vanbaalenii_PYR-1 FATKLFNATRFALLNGASPAPLPPSDQLTDADRWILGRLEEVRIEVDAAL MSMEG_4630|M.smegmatis_MC2_155 FATKLFNATRFALMNGAAPAPLPAASELTDADRWILGRLEEVRAEVDSAF TH_0609|M.thermoresistible__bu FVTKLFNATRFALLNGAAPAPLPDAAELTDADRWILGRLEEVRTEVDSAF MAB_1603|M.abscessus_ATCC_1997 FTTKLFNATRFALMNGAALGELPDVAELTDADRWILGRLEQVRAEVDGAL MMAR_3772|M.marinum_M FGTKLFNATRYALLNGAALAPLPPLGELTDADRWILGRLEEVRAEVDSAF MUL_3719|M.ulcerans_Agy99 FGTKLFNATRYALLNGAALAPLPPLGELTDADRWILGRLEEVRAEVDSAF Mb2475c|M.bovis_AF2122/97 FGTKLFNATRYALLNGAAPAPLPSPNELTDADRWILGRLEEVRAEVDSAF Rv2448c|M.tuberculosis_H37Rv FGTKLFNATRYALLNGAAPAPLPSPNELTDADRWILGRLEEVRAEVDSAF MLBr_01472|M.leprae_Br4923 FGTKLFNATRYALLNGAALVPLPALTALTDADRWILGRLEQVRAEVDSAF MAV_1724|M.avium_104 FCTKLFNATRYALLNGAQLAQLPPLDELTDADRWILGRLEEVRAEVDSAF * ********:**:*** ** *************:** :**.*: Mflv_2630|M.gilvum_PYR-GCK DNYEFNRACEALYHFAWDEFCDWYLELAKVQLGQEDPQTARTTAVLATVL Mvan_3951|M.vanbaalenii_PYR-1 DNYEFSRACESLYHFAWDEFCDWYLELAKVQLGQEEAHTARTTAVLAFAL MSMEG_4630|M.smegmatis_MC2_155 DNYEFNRACEALYHFAWDEFCDWYVELAKVQLGQEEVHTARTTAVLAAVL TH_0609|M.thermoresistible__bu DSYEFSRACETLYHFAWDEFCDWYVELAKVQLSEG---ISHTTAVLAAVL MAB_1603|M.abscessus_ATCC_1997 DRYEFSVACEGLYHFAWDEFCDWYLELAKVQMVDR---AESTRVVLATVL MMAR_3772|M.marinum_M DSYEFSRACEALYHFAWDEFCDWYVELAKTQLAEG---LSATTAVLAAGL MUL_3719|M.ulcerans_Agy99 DSYEFSRACEALYHFAWDEFCDWYVELAKTQLAEG---LSATTAVLAAGL Mb2475c|M.bovis_AF2122/97 DGYEFSRACESLYHFAWDEFCDWYLELAKTQLAQG---LTHTTAVLAAGL Rv2448c|M.tuberculosis_H37Rv DGYEFSRACESLYHFAWDEFCDWYLELAKTQLAQG---LTHTTAVLAAGL MLBr_01472|M.leprae_Br4923 DGYEFSRACEALYHFAWDEFCDWYLELAKAQLADG---LTHTTAVLAAAL MAV_1724|M.avium_104 DNYEFSRACESLYHFAWDEFCDWYVELAKTQLAEG---ITHTTAVLATTL * ***. *** *************:****.*: : * .*** * Mflv_2630|M.gilvum_PYR-GCK DVLLKLLHPVMPFVTEVLWKTLTGGESLVIADWPTATGFASDHAAAQRIT Mvan_3951|M.vanbaalenii_PYR-1 DVLLKLLHPVMPFVTEVLWKALTGGESLVIADWPTATGYAVDQGATQRVA MSMEG_4630|M.smegmatis_MC2_155 DTLLKLLHPVMPFVTETLWKTLTGGESVVVATWPEPSGFAPDTVATQRIT TH_0609|M.thermoresistible__bu DTLLKLLHPVMPFVTEKLWKTLTDGESLVIAKWPQPSGFSLDSIAAQRVA MAB_1603|M.abscessus_ATCC_1997 DTLLRLLHPVIPFVTEVLWKSVTGGESVVIAAWPTGSGIELDGTAAQRIA MMAR_3772|M.marinum_M DTLLRLLHPVIPFITEALWQALTGQESLVIADWPQPSGITLDPVAAQRIS MUL_3719|M.ulcerans_Agy99 DTLLRLLHPVIPFITEALWQALTGQESLVIADWPQPSGITLDPVAAQRIS Mb2475c|M.bovis_AF2122/97 DTLLRLLHPVIPFLTEALWLALTGRESLVSADWPEPSGISVDLVAAQRIN Rv2448c|M.tuberculosis_H37Rv DTLLRLLHPVIPFLTEALWLALTGRESLVSADWPEPSGISVDLVAAQRIN MLBr_01472|M.leprae_Br4923 DTLLRLLHPVMPFITETLWQALTQLESLVIATWPEPSGISLDLVAAQRIS MAV_1724|M.avium_104 DTLLRLLHPVIPFITEALWQALTGNESLVIADWPRSSGVGLDQVATQRIT *.**:*****:**:** ** ::* **:* * ** :* * *:**: Mflv_2630|M.gilvum_PYR-GCK DMQKLITEVRRFRSDQGLADRQKVPARLSEVSAAGLDAHVPAVTALAWLT Mvan_3951|M.vanbaalenii_PYR-1 DMQKLITEVRRFRSDQGLADRQKVPARLSDVAAAGLEEHVPAVTALAWLT MSMEG_4630|M.smegmatis_MC2_155 DMQKLITEVRRFRSDQGLADRQKVPARLTDVEAAGLTAQLPAVAALAWLT TH_0609|M.thermoresistible__bu DMQRLITEVRRFRSDQGLADRQKVPARLSDIPGADLQAQLPAIRALAWLT MAB_1603|M.abscessus_ATCC_1997 DMQKLVTEVRRFRSDQGLGDRQKVAARLSGVGEAGLDDQLAAVTSLAWLT MMAR_3772|M.marinum_M DMQNLVTEIRRFRSDQGLADRQKVPARLIGVEESDLGAQVAAVTSLAWLT MUL_3719|M.ulcerans_Agy99 DMQNLVTEIRRFRSDQGLADRQKVPARLIGVEESDLGAQVAAVTSLAWLT Mb2475c|M.bovis_AF2122/97 DMQKLVTEVRRFRSDQGLADRQKVPARMHGVRDSDLSNQVAAVTSLAWLT Rv2448c|M.tuberculosis_H37Rv DMQKLVTEVRRFRSDQGLADRQKVPARMHGVRDSDLSNQVAAVTSLAWLT MLBr_01472|M.leprae_Br4923 DMQKLVTEIRRFRSDQGLVDRQKVPARLSGVEDSDLATQVGFVTSLALLT MAV_1724|M.avium_104 DMQKLVTEVRRFRSDQGLADRQKVPARLAGVTESDLDTQVSAVTSLAWLT ***.*:**:********* *****.**: : :.* :: : :** ** Mflv_2630|M.gilvum_PYR-GCK PPAEGFTPSASVEVRLSAS---TVVVEVDTSGTVDVDAERRRLEKDLAAA Mvan_3951|M.vanbaalenii_PYR-1 PPADEFTPSAAVEVRLSTA---TVVVEVDTSGTVDVAAERRRLEKDLAAA MSMEG_4630|M.smegmatis_MC2_155 EAGDGFSPSASVEVRLSQG---TVVVEVDTSGTVDVEAERRRLEKDLGGR TH_0609|M.thermoresistible__bu DAGADFNPSAALEVRLSKG---TVVVELDTRGSVDVEAERRRTEKDLAAA MAB_1603|M.abscessus_ATCC_1997 PAEEGFSPTASVEVRLSGA---TVTVEVDTSGTVDVEAERRRLEKDLAAA MMAR_3772|M.marinum_M APGEGFAPSVSLEVRLGPSMNHTVVVELDTSGTIDVAAERRRLEKDLAAA MUL_3719|M.ulcerans_Agy99 APGEGFAPSVSLEVRLGPSMNHTVVVELDTSGTIDVAAERRRLEKDLAAA Mb2475c|M.bovis_AF2122/97 EPGPDFEPSVSLEVRLGPEMNRTVVVELDTSGTIDVAAERRRLEKELAGA Rv2448c|M.tuberculosis_H37Rv EPGPDFEPSVSLEVRLGPEMNRTVVVELDTSGTIDVAAERRRLEKELAGA MLBr_01472|M.leprae_Br4923 AASNDFRPSALLEVRLGPNKDRAVVVELDTSGTIDVAAERRRMEKDLAAA MAV_1724|M.avium_104 DAGPDFRPSASVEVRLRGG---TVVVELDTSGSIDVAAERRRLEKDLAAA . * *:. :**** :*.**:** *::** ***** **:*.. Mflv_2630|M.gilvum_PYR-GCK QKELAGTSAKLGNDAFLAKAPADVVDKIRARRQVAGEEVDRITARLSALP Mvan_3951|M.vanbaalenii_PYR-1 QKELSGTSGKLGNEAFLAKAPADVVDKIRARQQVANEEVERIQARLAALS MSMEG_4630|M.smegmatis_MC2_155 PEGTGHHHGQTRQRGLPVQG-----ARPGGRQDPGQASPGQ--------- TH_0609|M.thermoresistible__bu RRELESTSKKLENEAFLAKAPAEVVEKIRNRQRLAAEEVDRLTARLAALK MAB_1603|M.abscessus_ATCC_1997 RKELDGTTSKLGNDAFLAKAPEAVVEKIRVRQQVATEEVERITARLAALA MMAR_3772|M.marinum_M EKELVSTAAKLANADFLAKAPEAVVGKIRDRQRLAQEESDRITTRLAALQ MUL_3719|M.ulcerans_Agy99 EKELVSAAAKLANADFLAKAPEAVVGKIRDRQRLAQEESDRITTRLAALQ Mb2475c|M.bovis_AF2122/97 QKELASTAAKLANADFLAKAPDAVIAKIRDRQRVAQQETERITTRLAALQ Rv2448c|M.tuberculosis_H37Rv QKELASTAAKLANADFLAKAPDAVIAKIRDRQRVAQQETERITTRLAALQ MLBr_01472|M.leprae_Br4923 QKELASTAAKLANADFLAKAPEAVVVKIRDRQRMAKEETDRIIARLAGLQ MAV_1724|M.avium_104 HKELASTTAKLANEDFLAKAPPHVVDKIRDRQRLAQEESERINARLAVLQ . : : : .:. : *: . . : Mflv_2630|M.gilvum_PYR-GCK AGE Mvan_3951|M.vanbaalenii_PYR-1 ASE MSMEG_4630|M.smegmatis_MC2_155 --- TH_0609|M.thermoresistible__bu DS- MAB_1603|M.abscessus_ATCC_1997 --- MMAR_3772|M.marinum_M --- MUL_3719|M.ulcerans_Agy99 --- Mb2475c|M.bovis_AF2122/97 --- Rv2448c|M.tuberculosis_H37Rv --- MLBr_01472|M.leprae_Br4923 --- MAV_1724|M.avium_104 ---