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VTDNAYPKLAGGAPDLPALELEVLDYWSRDDTFRASIARRDGAPEYVFYDGPPFANGLPHYGHLLTGYVK DIVPRYRTMRGYKVERRFGWDTHGLPAELEVERQLGITDKSQIEAMGIAAFNDACRASVLRYTDEWQAYV TRQARWVDFDNDYKTLDLAYMESVIWAFKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQ DPAVTVGFKVVGGQPDNGLDGAYLLVWTTTPWTLPSNLAVAVSPDITYVQVQAGDRRFVLAEARLAAYAR ELGEEPVVLGTYRGAELLGTRYLPPFAYFMDWPNAFQVLAGDFVTTDDGTGIVHMAPAYGEDDMVVAEAV GIAPVTPVDSKGRFDVTVADYQGQHVFDANAQIVRDLKTQSGPAAVNGPVLIRHETYEHPYPHCWRCRNP LIYRSVSSWFVRVTDFRDRMVELNQQITWYPEHVKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPA YPRIDVYGSLDELERDFGVRPANLHRPYIDELTRPNPDDPTGRSTMRRIPDVLDVWFDSGSMPYAQVHYP FENLDWFQGHYPGDFIVEYIGQTRGWFYTLHVLATALFDRPAFKTCVAHGIVLGFDGQKMSKSLRNYPDV TEVFDRDGSDAMRWFLMASPILRGGNLIVTEQGIRDGVRQVLLPLWNTYSFLALYAPKVGTWRVDSVHVL DRYILAKLAVLRDDLSESMEVYDIPGACEHLRQFTEALTNWYVRRSRSRFWAEDADAIDTLHTVLEVTTR LAAPLLPLITEIIWRGLTRERSVHLTDWPAPDLLPSDADLVAAMDQVRDVCSAASSLRKAKKLRVRLPLP KLIVAVENPQLLRPFVDLIGDELNVKQVELTDAIDTYGRFELTVNARVAGPRLGKDVQAAIKAVKAGDGV INPDGTLLAGPAVLTPDEYNSRLVAADPESTAALPDGAGLVVLDGTVTAELEAEGWAKDRIRELQELRKS TGLDVSDRIRVVMSVPAEREDWARTHRDLIAGEILATDFEFADLADGVAIGDGVRVSIEKT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1536 | ileS | - | 100% (1041) | isoleucyl-tRNA synthetase |
| M. tuberculosis H37Rv | Rv2448c | valS | 6e-50 | 24.43% (831) | valyl-tRNA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1563 | ileS | 0.0 | 99.90% (1041) | isoleucyl-tRNA synthetase |
| M. gilvum PYR-GCK | Mflv_3644 | ileS | 0.0 | 81.56% (1036) | isoleucyl-tRNA synthetase |
| M. leprae Br4923 | MLBr_01195 | ileS | 0.0 | 84.32% (1059) | isoleucyl-tRNA synthetase |
| M. abscessus ATCC 19977 | MAB_2705c | ileS | 0.0 | 77.04% (1054) | isoleucyl-tRNA synthetase |
| M. marinum M | MMAR_2356 | ileS | 0.0 | 87.11% (1055) | isoleucyl-tRNA synthetase IleS |
| M. avium 104 | MAV_3235 | ileS | 0.0 | 88.31% (1035) | isoleucyl-tRNA synthetase |
| M. smegmatis MC2 155 | MSMEG_3169 | ileS | 0.0 | 82.65% (1043) | isoleucyl-tRNA synthetase |
| M. thermoresistible (build 8) | TH_3715 | - | 0.0 | 82.46% (1049) | PUTATIVE Isoleucyl-tRNA synthetase |
| M. ulcerans Agy99 | MUL_1532 | ileS | 0.0 | 86.73% (1055) | isoleucyl-tRNA synthetase |
| M. vanbaalenii PYR-1 | Mvan_2769 | ileS | 0.0 | 80.27% (1024) | isoleucyl-tRNA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3644|M.gilvum_PYR-GCK --------------------MAQETHDVTAYP--------KPTSGAPKFP
Mvan_2769|M.vanbaalenii_PYR-1 ---------------------------MTAYP--------KFTAGAPRFP
MSMEG_3169|M.smegmatis_MC2_155 ---------------------------MTAYP--------KP--AAPNFP
TH_3715|M.thermoresistible__bu VVPRRSRYPARCRPRVLKTWAQENREIVTAYP--------KPSPGAPNFP
Rv1536|M.tuberculosis_H37Rv -----------------MTD--------NAYP--------KLAGGAPDLP
Mb1563|M.bovis_AF2122/97 -----------------MTD--------NAYP--------KLAGGAPDLP
MLBr_01195|M.leprae_Br4923 -----------------MTN--------SAYPRTDLG--ADQRGGSPNFP
MMAR_2356|M.marinum_M -----------------MTD--------STYPRSNLG--ADHRGGSPDFP
MUL_1532|M.ulcerans_Agy99 -----------------MTD--------STYPRSNLG--ADHRGGSPDFP
MAV_3235|M.avium_104 -----------------MTDNLGFQADREAQPADSVQTYPKPAGGAPDFP
MAB_2705c|M.abscessus_ATCC_199 ---------------------------MDAYPRTDLG--ADQRSGSPNLP
: * . .:* :*
Mflv_3644|M.gilvum_PYR-GCK ALEAEVLQYWDSDDTFRASIAQRDGAPEFVFYDGPPFANGLPHYGHLLTG
Mvan_2769|M.vanbaalenii_PYR-1 ALEADVLSYWDTDDTFRASIARREGAPEYVFYDGPPFANGLPHYGHLLTG
MSMEG_3169|M.smegmatis_MC2_155 ERELEVLDYWAKDDTFRASVERREGAEEYVFYDGPPFANGLPHYGHLLTG
TH_3715|M.thermoresistible__bu ALEQEVLEYWSADDTFRASIERRADAPEYVFYDGPPFANGLPHYGHLLTG
Rv1536|M.tuberculosis_H37Rv ALELEVLDYWSRDDTFRASIARRDGAPEYVFYDGPPFANGLPHYGHLLTG
Mb1563|M.bovis_AF2122/97 ALELEVLDYWSRDDTFRASIARRDGAPEYVFYDGPPFANGLPHYGHLLTG
MLBr_01195|M.leprae_Br4923 ALEAQVLDYWSNDDTFRASIARCDDAPEYVFYDGPPFANGLPHYGHLLTG
MMAR_2356|M.marinum_M ELETQVLDYWARDETFRASIERRDGAPEYVFYDGPPFANGLPHYGHLLTG
MUL_1532|M.ulcerans_Agy99 ELETQVLDYWARDETFRASIERRDGAPEYVFYDGPPFANGLPHYGHLLTG
MAV_3235|M.avium_104 ALELEVLDYWARDDTFRASIARRDGAEEYVFYDGPPFANGLPHYGHLLTG
MAB_2705c|M.abscessus_ATCC_199 ALEKQVLRYWDQDDTFRASIANRDGAPEYVFYDGPPFANGLPHYGHLLTG
* :** ** *:*****: . .* *:*********************
Mflv_3644|M.gilvum_PYR-GCK YVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVQRQLGITDKAQIEQMG
Mvan_2769|M.vanbaalenii_PYR-1 YVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVQRQLGITDKAQIEEMG
MSMEG_3169|M.smegmatis_MC2_155 YVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVQRQLDITDKSQIEEMG
TH_3715|M.thermoresistible__bu YVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVQRQLGITDKAQIEQMG
Rv1536|M.tuberculosis_H37Rv YVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVERQLGITDKSQIEAMG
Mb1563|M.bovis_AF2122/97 YVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVERQLGITDKSQIEAMG
MLBr_01195|M.leprae_Br4923 YVKDIVPRYRTMCGYKVERRFGWDTHGLPAELEVERQLGITDKSQIDAMG
MMAR_2356|M.marinum_M YVKDIVPRYRTMRGFKVERRFGWDTHGLPAELEVERQLGITDKSQIDAMG
MUL_1532|M.ulcerans_Agy99 YVKDIVPRYRTMRGFKVERRFGWDTHGLPAELEVERQLGITDKSQIDAMG
MAV_3235|M.avium_104 YVKDIVPRYRTMRGNKVERRFGWDTHGLPAELEVERQLGITDKSQIDDMG
MAB_2705c|M.abscessus_ATCC_199 YVKDIVPRYQTMRGYQVDRRFGWDTHGLPAELEVERQLGITDKSQIDSMG
*********:** * :*:****************:***.****:**: **
Mflv_3644|M.gilvum_PYR-GCK IEKFNDACRASVLKYTDEWRDYVTRQARWVDFDNDYKTLDIGFMESVIWV
Mvan_2769|M.vanbaalenii_PYR-1 IEKFNDACRESVLKYTNEWREYVTRQARWVDFDNDYKTLDIGFMESVIWV
MSMEG_3169|M.smegmatis_MC2_155 IEKFNDACRASVLKYTNEWQAYVTRQARWVDFDNDYKTLDLPFMESVIWA
TH_3715|M.thermoresistible__bu IEKFNDACRASVLRYTKEWREYVTRQARWVDFDNDYKTLDLGYMESVIWA
Rv1536|M.tuberculosis_H37Rv IAAFNDACRASVLRYTDEWQAYVTRQARWVDFDNDYKTLDLAYMESVIWA
Mb1563|M.bovis_AF2122/97 IAAFNDACRASVLRYTDEWQAYVTRQARWVDFDNDYKTLDLAYMESVIWA
MLBr_01195|M.leprae_Br4923 IAAFNEACRKSVLRYTEEWQAYVTRQARWVDFDNDYKTLDLSYMESVIWA
MMAR_2356|M.marinum_M IAAFNDACRASVLRYTDEWQQYVTRQARWVDFDNDYKTLDLGYMESVIWA
MUL_1532|M.ulcerans_Agy99 IAAFNDACRASVLRYTDEWQQYVTRQARWVDFDNDYKTVDLGYMESVIWA
MAV_3235|M.avium_104 IAAFNDACRESVLRYTDEWRAYVTRQARWVDFDNDYKTLDLPYMESVIWA
MAB_2705c|M.abscessus_ATCC_199 IAEFNDACRESVLRYTKEWREYVTRQARWVDFDNDYKTLDLTFMESVIWA
* **:*** ***:**.**: *****************:*: :******.
Mflv_3644|M.gilvum_PYR-GCK FKQLWDKGLAYEGNRVLPYCWNDETPLSSHELRMDDDVYQNRQDPALTVG
Mvan_2769|M.vanbaalenii_PYR-1 FKQLWDKGLAYEGNRVLPYCWNDETPLSSHELRMDDDVYQNRQDPALTVG
MSMEG_3169|M.smegmatis_MC2_155 FKQLWDKGLAYEGNRVLPYCWNDETPLSSHELRMDDDVYQSRQDPALTVG
TH_3715|M.thermoresistible__bu FKQLWDKGLAYEGIRVLPYCWNDETPLSSHELRMDDDVYQSRQDPAITVG
Rv1536|M.tuberculosis_H37Rv FKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTVG
Mb1563|M.bovis_AF2122/97 FKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTVG
MLBr_01195|M.leprae_Br4923 FKQLWDKGLAYESYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTLG
MMAR_2356|M.marinum_M FRQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPALTVG
MUL_1532|M.ulcerans_Agy99 FRQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPALTVG
MAV_3235|M.avium_104 FKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPALTVG
MAB_2705c|M.abscessus_ATCC_199 FKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTVG
*:**********. *******.******.***********.*****:*:*
Mflv_3644|M.gilvum_PYR-GCK FRISSG--------------ELEGAYLLVWTTTPWTLPSNQAVAVNPDVT
Mvan_2769|M.vanbaalenii_PYR-1 YRIVGGPADERSREERTAKSDLVGAYLLIWTTTPWTLPSNQAVAVNPEVT
MSMEG_3169|M.smegmatis_MC2_155 FRIDEG--------------PLTDSYLLIWTTTPWTLPSNQAVAVGPDIT
TH_3715|M.thermoresistible__bu FRVPDG--------------PLAGSHLLIWTTTPWTLPSNQAVAVHPDVT
Rv1536|M.tuberculosis_H37Rv FKVVGGQP----------DNGLDGAYLLVWTTTPWTLPSNLAVAVSPDIT
Mb1563|M.bovis_AF2122/97 FKVVGGQP----------DNGLDGAYLLVWTTTPWTLPSNLAVAVSPDIT
MLBr_01195|M.leprae_Br4923 FKVLGGD-----------DEDLVGAYLLVWTTTPWTLPSNLAVAVHPDVT
MMAR_2356|M.marinum_M FKVVDGEP----------QGELAGAYLLVWTTTPWTLPSNLAVAVHPDVT
MUL_1532|M.ulcerans_Agy99 FKVVDGEP----------QGELAGAYLLVWTTTPWTLPSNLAVAVHPDVT
MAV_3235|M.avium_104 FKVVGGE--------------LDGAHLLIWTTTPWTLPSNLAVAVHPEVT
MAB_2705c|M.abscessus_ATCC_199 YRIAGNED--------SRWATLDGARLLIWTTTPWTLPSNLAVAVNPEVT
::: . * .: **:*********** **** *::*
Mflv_3644|M.gilvum_PYR-GCK YVVVE--SDGRRYVLAEARLAAYAREFGEEPAVVATYRGADLLDVGYVPP
Mvan_2769|M.vanbaalenii_PYR-1 YVVVE--ADGRRYVLAEARLGAYARELGEEPTVVATYTGRELLDLHYAPP
MSMEG_3169|M.smegmatis_MC2_155 YVHVEG-ADGRRYLLAEARLGAYARELGEEPKVLATFTGRDLLGTHYVPP
TH_3715|M.thermoresistible__bu YVQVAA-PDGRRYVLAEARLAAYARELGEEPEVLARFPGSELVETRYLPP
Rv1536|M.tuberculosis_H37Rv YVQVQ--AGDRRFVLAEARLAAYARELGEEPVVLGTYRGAELLGTRYLPP
Mb1563|M.bovis_AF2122/97 YVQVQ--AGDRRFVLAEARLAAYARELGEEPVVLGTYRGAELLGTRYLPP
MLBr_01195|M.leprae_Br4923 YVDVR--AGDRRFVLAQARLTAYARELGDEPEVLATYRGADLLGRHYLPP
MMAR_2356|M.marinum_M YVQVR--VGDRRLVLAEARLAAYTRELGEEPEVIGSYRGADLLGMRYLPP
MUL_1532|M.ulcerans_Agy99 YVQVR--VGDRRLVLAEARLAAYTRELGEEPEVIGSYRGADLLGIRYLPP
MAV_3235|M.avium_104 YVQVR--SGDRRFVLAQPRLAAYARELGPEPEILGSYRGAELLGTRYLPP
MAB_2705c|M.abscessus_ATCC_199 YAVVKPEDSEDRYLLAQARVGAYARELGEEPTVLDTYTGAELLGLRYLPP
*. * . * :**:.*: **:**:* ** :: : * :*: * **
Mflv_3644|M.gilvum_PYR-GCK FPYFMDSP--NAFRVLPAEFVSTEDGTGLVHMSPAYGEDDMATAQAGGID
Mvan_2769|M.vanbaalenii_PYR-1 FPYFMDSP--NAFRVLPGEFVSTEDGTGLVHMSPAYGEDDMATAQAGGIE
MSMEG_3169|M.smegmatis_MC2_155 FPYFMGSA--NAFQVLAGDFVSTEDGTGIVHMAPAYGEDDKATADAADIV
TH_3715|M.thermoresistible__bu FTYFADAA--NSFRVLPADFVSTEDGTGIVHMAPAYGEDDMDVAKAADIT
Rv1536|M.tuberculosis_H37Rv FAYFMDWP--NAFQVLAGDFVTTDDGTGIVHMAPAYGEDDMVVAEAVGIA
Mb1563|M.bovis_AF2122/97 FAYFMDWP--NAFQVLAGDFVTTDDGTGIVHMAPAYGEDDMVVAEAVGIA
MLBr_01195|M.leprae_Br4923 FQYFYESAR-NAFQVLPGDFVTTDDGTGIVHIAPAYGEDDMATADKVGIV
MMAR_2356|M.marinum_M FAYFMDSP--NAFAVLAGEFVTTEDGTGIVHMAPAYGEDDMAVTSPVGIE
MUL_1532|M.ulcerans_Agy99 FAYFMDSP--NAFAVLAGEFVTTEDGTGIVHMAPAYGEDDMAVTSPVGIE
MAV_3235|M.avium_104 FPYFMDSP--NAFRVLAGEFVTTEDGTGIVHLAPAYGEDDMAVADAAGIA
MAB_2705c|M.abscessus_ATCC_199 FPYFQQDASPNAFTVLSGDYVTTDDGTGIVHMAPAYGEEDKNVTDRAQIT
* ** . *:* **..::*:*:****:**::*****:* .:. *
Mflv_3644|M.gilvum_PYR-GCK AVTPVDAKGRFDASVPDYAGQHVFDANPQIIRDLKNGTGAAATNGAVLLR
Mvan_2769|M.vanbaalenii_PYR-1 AVTPVDAKGRFDATVPDYAGQHVFDANPQIIRDLKNQSGPAQANGAVLLR
MSMEG_3169|M.smegmatis_MC2_155 AVTPVDSKGRFDESVPDYVGQHVFEANPQIIRDLKNGDGSAGANGAVVLR
TH_3715|M.thermoresistible__bu AVTPVDAKGCFDASVPDYQGRHVFDANPQIIRDLKNQAGPAGHNGAVLLR
Rv1536|M.tuberculosis_H37Rv PVTPVDSKGRFDVTVADYQGQHVFDANAQIVRDLKTQSGPAAVNGPVLIR
Mb1563|M.bovis_AF2122/97 PVTPVDSKGRFDVTVADYQGQHVFDANAQIVRDLKTQSGPAAVNGPVLIR
MLBr_01195|M.leprae_Br4923 PVTPVDSNGCFDATVPDYQGQHVFEANAQIIRDLKNQSGSAAVNGAVLLR
MMAR_2356|M.marinum_M PVTPVDAKGRFDSSVPDYQGQHVFDANAQIIRDLKNQSGPAAANGAVLIR
MUL_1532|M.ulcerans_Agy99 PVTPVDAKGRFDSSVPDYQGQHVFDANAQIIRDLKNQSGPAAANGAVLIR
MAV_3235|M.avium_104 PVTPVDSNGRFDAAVPDYQGLNVFDANPQIIRDLKNGSGAAAANAPVLLR
MAB_2705c|M.abscessus_ATCC_199 PVTPVDSKGRFDATVPDYEGQQVFDANAQIIKDLKNGTGAAGLNGAVLLR
.*****::* ** :*.** * :**:**.**::***. *.* *..*::*
Mflv_3644|M.gilvum_PYR-GCK HDSYEHSYPHCWRCRNPLIYRAVSSWFVKVTQFRDRMVELNQEITWYPEH
Mvan_2769|M.vanbaalenii_PYR-1 HDTYEHSYPHCWRCRNPLIYRAVSSWFIKVTQFRDRMVELNQEITWYPEH
MSMEG_3169|M.smegmatis_MC2_155 HETYEHSYPHCWRCRNPLIYRAVSSWFVRVTEFRDRMVELNQQITWYPEH
TH_3715|M.thermoresistible__bu HDTYEHSYPHCWRCRNPLIYRAVSSWFIKVTEFRDRMVELNQQITWYPGH
Rv1536|M.tuberculosis_H37Rv HETYEHPYPHCWRCRNPLIYRSVSSWFVRVTDFRDRMVELNQQITWYPEH
Mb1563|M.bovis_AF2122/97 HETYEHPYPHCWRCRNPLIYRSVSSWFVRVTDFRDRMVELNQQITWYPEH
MLBr_01195|M.leprae_Br4923 HETYEHPYPHCWRCRNPLIYRAVSSWFVAVTEFRDRMVELNQQITWYPEH
MMAR_2356|M.marinum_M HETYEHPYPHCWRCRNPLIYRAVSSWFVTVTKFRERMVELNQQITWYPEH
MUL_1532|M.ulcerans_Agy99 HETYEHPYPHCWRCRNPLIYRAVSSWFVTVTKFRERMVELNQQITWCPEH
MAV_3235|M.avium_104 HETYEHPYPHCWRCRNPLIYRAVSSWFVAVTRFRDRMVELNQQITWYPEH
MAB_2705c|M.abscessus_ATCC_199 HETYDHSYPHCWRCRNPLIYRAVSSWFIKVTEFRDRMVQLNEQITWYPEH
*::*:*.**************:*****: ** **:***:**::*** * *
Mflv_3644|M.gilvum_PYR-GCK VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
Mvan_2769|M.vanbaalenii_PYR-1 VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
MSMEG_3169|M.smegmatis_MC2_155 VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
TH_3715|M.thermoresistible__bu VKDGQFGKWLANARDWSISRNRYWGTPIPVWVSDNPEYPRIDVYGSLDEL
Rv1536|M.tuberculosis_H37Rv VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
Mb1563|M.bovis_AF2122/97 VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
MLBr_01195|M.leprae_Br4923 VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPDYPRIDVYGSLDEL
MMAR_2356|M.marinum_M VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
MUL_1532|M.ulcerans_Agy99 VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
MAV_3235|M.avium_104 VKDGQFGKWLAGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
MAB_2705c|M.abscessus_ATCC_199 VKHGQFGKWLEGARDWSVSRNRYWGSPIPVWKSDDPAYPRIDVYGSLDEL
**.******* .*****:*******:***** **:* *************
Mflv_3644|M.gilvum_PYR-GCK ERDFGVRPDNLHRPFIDELTRPNPDDPTGRSTMRRIEDVLDVWFDSGSMP
Mvan_2769|M.vanbaalenii_PYR-1 ERDFGVRPDNLHRPFIDELTRPNPDDPTGRSTMRRIEDVLDVWFDSGSMP
MSMEG_3169|M.smegmatis_MC2_155 ERDFGVRPDNLHRPFIDQLTRPNPDDPTGKSTMRRIEDVLDVWFDSGSMP
TH_3715|M.thermoresistible__bu ERDFGVRPTDLHRPYIDELTRPNPDDPTGKSTMRRIPDVLDVWFDSGSMP
Rv1536|M.tuberculosis_H37Rv ERDFGVRPANLHRPYIDELTRPNPDDPTGRSTMRRIPDVLDVWFDSGSMP
Mb1563|M.bovis_AF2122/97 ERDFGVRPANLHRPYIDELTRPNPDDPTGRSTMRRIPDVLDVWFDSGSMP
MLBr_01195|M.leprae_Br4923 ERDFGVRPTNLHRPYIDELTRPNPDDPTGLSTMRRIPDVFDVWFDSGSMP
MMAR_2356|M.marinum_M ERDFGVRPTNLHRPYIDELTRPNPDDPTGQSTMRRIPDVLDVWFDSGSMP
MUL_1532|M.ulcerans_Agy99 ERDFGVRPINLHRPYIDELTRPNPDDPTGQSTMRRIPDVLDVWFDSGSMP
MAV_3235|M.avium_104 ERDFGVRPDNLHRPYIDELTRPNPDDPSGRSTMRRIPDVLDVWFDSGSMP
MAB_2705c|M.abscessus_ATCC_199 ERDFGVRPTNLHRPYIDELTRPNPDDPTGKSTMRRIPDIFDVWFDSGSMP
******** :****:**:*********:* ****** *::**********
Mflv_3644|M.gilvum_PYR-GCK YGQVHYPFENQQWFE------------SHYPGDFIVEYIGQTRGWFYTLH
Mvan_2769|M.vanbaalenii_PYR-1 YGQVHYPFENSDWFD------------SHFPGDFIVEYIGQTRGWFYTLH
MSMEG_3169|M.smegmatis_MC2_155 YAQVHYPFENREWFDGASGEE------AHFPGDFIVEYIGQTRGWFYTLH
TH_3715|M.thermoresistible__bu FAQVHYPFENADWFDGSDDQE------PHFPGDFIVEYIGQTRGWFYTLH
Rv1536|M.tuberculosis_H37Rv YAQVHYPFENLDWFQG------------HYPGDFIVEYIGQTRGWFYTLH
Mb1563|M.bovis_AF2122/97 YAQVHYPFENLDWFQG------------HYPGDFIVEYIGQTRGWFYTLH
MLBr_01195|M.leprae_Br4923 YAQVHYPFENDDWFDGFDSADSDKQVDAHYPGDFIVEYIGQARGWFYTLH
MMAR_2356|M.marinum_M YAQVHYPFENGDWFLGGAAGDAG----AHYPGDFIVEYIGQTRGWFYTLH
MUL_1532|M.ulcerans_Agy99 YAQVHYPFENGDWFLGGAAGDAG----AHYPGDFIVEYIGQTRGWFYTLH
MAV_3235|M.avium_104 YAQVHYPFENRDWFET------------HYPGDFIVEYIGQTRGWFYTLH
MAB_2705c|M.abscessus_ATCC_199 YAQVHYPFENAEWFEK------------HFPADFIVEYIGQTRGWFYVMH
:.******** :** *:*.*********:*****.:*
Mflv_3644|M.gilvum_PYR-GCK VLATALFDRPAFRTCVSHGIVLGNDGQKMSKSLRNYPDVSEVFDRDGSDA
Mvan_2769|M.vanbaalenii_PYR-1 ILATALFDRPAFRTCVSHGIVLGNDGQKMSKSLRNYPDVSEVFDRDGSDA
MSMEG_3169|M.smegmatis_MC2_155 VLATALFDKPAFKTCVSHGIVLGNDGQKMSKSLRNYPDVSEVFDRDGSDA
TH_3715|M.thermoresistible__bu ILATALFDKPAFKTCVAHGIVLGNDGQKMSKSLRNYPDVTEVFDRDGSDA
Rv1536|M.tuberculosis_H37Rv VLATALFDRPAFKTCVAHGIVLGFDGQKMSKSLRNYPDVTEVFDRDGSDA
Mb1563|M.bovis_AF2122/97 VLATALFDRPAFKTCVAHGIVLGFDGQKMSKSLRNYPDVTEVFDRDGSDA
MLBr_01195|M.leprae_Br4923 VLATALFDRPAFKTCIAHGVVLGSNGQKMSKSLRNYPDVTEIFDRDGSDA
MMAR_2356|M.marinum_M VLATALFDRPAFKTCVAHGIVLGSDGQKMSKSLRNYPDVAEVFHRDGSDA
MUL_1532|M.ulcerans_Agy99 VLATALFDRPAFKTCVAHGIVLGFDGQKMSKSLRNYPDVAEVFHRDGSDA
MAV_3235|M.avium_104 VLATALFDRPAFKTCVAHGIVLGSDGQKMSKSLRNYPDVSEVFDRDGSDA
MAB_2705c|M.abscessus_ATCC_199 VLATALFDRPAFRTCVSHGIVLGNDGQKMSKSLRNYPDVNEVFDRDGSDA
:*******:***:**::**:*** :************** *:*.******
Mflv_3644|M.gilvum_PYR-GCK MRWFLMASPILRGGNLIVTEQGIREGVRQVLLPLWNAYTFLALYAPEKGT
Mvan_2769|M.vanbaalenii_PYR-1 MRWFLMASPILRGGNLIVTEQGIREGVRQVLLPLWNAYTFLALYAPSKGT
MSMEG_3169|M.smegmatis_MC2_155 MRWFLMASPILRGGNLIVTEQGIREGVRQVLLPLWNAYSFLALYAPEKGT
TH_3715|M.thermoresistible__bu MRWFLMASPILRGGNLIVTEQGIRDGVRQVQLPLWNAYTFLALYAPKKGA
Rv1536|M.tuberculosis_H37Rv MRWFLMASPILRGGNLIVTEQGIRDGVRQVLLPLWNTYSFLALYAPKVGT
Mb1563|M.bovis_AF2122/97 MRWFLMASPILRGGNLIVTEQGIRDGVRQVLLPLWNTYSFLALYAPKVGT
MLBr_01195|M.leprae_Br4923 MRWFLMASPILRGGNLIITEPGIREGMRQVLLPLWNAYSFLALYAPKIGT
MMAR_2356|M.marinum_M MRWFLMASPILRGGNLIVTEQGIREGVRQVLLPFWNAYSFLALYAPKVGT
MUL_1532|M.ulcerans_Agy99 MRWFLMASPILRGGNLIVTEQGIREGVRQVLLPFWNAYSFLALYAPKVGT
MAV_3235|M.avium_104 MRWFLMASPILRGGNLIVTEQGIRDGVRQVLLPFWNAYSFLALYAPKVGT
MAB_2705c|M.abscessus_ATCC_199 MRWFLMASPILRGGNLIVTEQGIREGVRQVILPLWNAWSFLQLYAPKPGT
*****************:** ***:*:*** **:**:::** ****. *:
Mflv_3644|M.gilvum_PYR-GCK WRTDSTHVLDRYILAKLAQLRDDLTASLDVCDISQACDQLRQFTEALTNW
Mvan_2769|M.vanbaalenii_PYR-1 WRTDSEHVLDRYILAKLAVLRDDLTASLDVCDISQACDQLRQFTEALTNW
MSMEG_3169|M.smegmatis_MC2_155 WRTDSKNVLDRYILAKLAQLRDDLTSALDVCDISGACDELRQFAESLTNW
TH_3715|M.thermoresistible__bu WRTDSRHVLDRYILAKLAALRDDLTDAMEVCDISGACEQLRQFIEALTNW
Rv1536|M.tuberculosis_H37Rv WRVDSVHVLDRYILAKLAVLRDDLSESMEVYDIPGACEHLRQFTEALTNW
Mb1563|M.bovis_AF2122/97 WRVDSVHVLDRYILAKLAVLRDDLSESMEVYDIPGACEHLRQFTEALTNW
MLBr_01195|M.leprae_Br4923 WHTDVSHVLDRYILAKLAVLRDDLSQAMEVCDISGACEQLRQFTEPLTNW
MMAR_2356|M.marinum_M WRTDSDHVLDRYILAKLAVLRDDLTQAMEVCDISGACEQLRQFTEALTNW
MUL_1532|M.ulcerans_Agy99 WRTDSDHVLDRYILAKLAVLRDDLTQAMEVCDISGACEQLRQFTEALTNW
MAV_3235|M.avium_104 WRTDSTQVLDRYILAKLAELRDDLTREMDACDISRACEQLRQFTEALTNW
MAB_2705c|M.abscessus_ATCC_199 WRTDSKQVLDRYILAKLAQLRDDLTTSMDDCDVSVACEQLRQFTDALTNW
*:.* :*********** *****: :: *:. **:.**** :.****
Mflv_3644|M.gilvum_PYR-GCK YVRRSRSRFWDEDADAIDTLHTVLEVTGRLAAPLLPLITEVIWRGVTGER
Mvan_2769|M.vanbaalenii_PYR-1 YVRRSRSRFWEEDADAIDTLHTVLEVTSRLAAPLLPLITEVIWRGVTGER
MSMEG_3169|M.smegmatis_MC2_155 YVRRSRSRFWDEDPDAIDTLHTVLEVTCRLAAPLLPLATEVIWRGLTGER
TH_3715|M.thermoresistible__bu YVRRSRSRFWDEDPDAIDTLHTVLEVTGRLAAPLLPMTTEVIWRGITGER
Rv1536|M.tuberculosis_H37Rv YVRRSRSRFWAEDADAIDTLHTVLEVTTRLAAPLLPLITEIIWRGLTRER
Mb1563|M.bovis_AF2122/97 YVRRSRSRFWAEDADAIDTLHTVLEVTTRLAAPLLPLITEIIWRGLTRER
MLBr_01195|M.leprae_Br4923 YLRRSRARFWDEDVDAIDTLHTVLEVTARLAAPLLPLITEIIWRSVTGGR
MMAR_2356|M.marinum_M YVRRSRSRFWQEDVDAIDTLHTVLEITARLAAPLLPLVTEVIWRGLTGER
MUL_1532|M.ulcerans_Agy99 YVRRSRSRFWQEDVDAIDTLHTVLEMTARLAAPLLPLVTEVIWRGLTGER
MAV_3235|M.avium_104 YVRRSRSRFWSEDADAIDTLHTVLEVTARLAAPLLPSVTELVWRGLTGGR
MAB_2705c|M.abscessus_ATCC_199 YVRRSRSRFWEEDADAIDTLHTVLETTCRLAAPLLPMTTEVIWRGLTGER
*:****:*** ** *********** * ******** **::**.:* *
Mflv_3644|M.gilvum_PYR-GCK SVHLTDWPEAGVLPADPQLVADMDLVRDVASAGSSLRKAQKLRVRLPLLK
Mvan_2769|M.vanbaalenii_PYR-1 SVHLTDWPEAGAVPADPQLVADMDLVREVASAGSSLRKAKKLRVRLPLLK
MSMEG_3169|M.smegmatis_MC2_155 SVHLTDWPEADVLPKDPDLVAAMDQVREVCSVGSSLRKAKKLRVRLPLPK
TH_3715|M.thermoresistible__bu SVHLTDWPESGLLPSDPDLVEAMDQVRDVCSAASSLRKAKKLRVRLPLPK
Rv1536|M.tuberculosis_H37Rv SVHLTDWPAPDLLPSDADLVAAMDQVRDVCSAASSLRKAKKLRVRLPLPK
Mb1563|M.bovis_AF2122/97 SVHLTDWPAPDLLPSDADLVAAMDQVRDVCSAASSLRKAKKLRVRLPLPK
MLBr_01195|M.leprae_Br4923 SVHLTDWPQANQLPADPDLVAVMDQVRQVCSAASSLRKAKKLRVRLPLPK
MMAR_2356|M.marinum_M SVHLTDWPQAGEVPADAELVAAMDQVREVCSAASSLRKAKKLRVRLPLPK
MUL_1532|M.ulcerans_Agy99 SVHLTDWPQAGEVPADAELVAAMDQVREVCSAASSLRKAKKLRVRLPLPK
MAV_3235|M.avium_104 SVHLTDWPRSGELPADPGLVAAMDQVREVCSAASSLRKAKKLRVRLPLPK
MAB_2705c|M.abscessus_ATCC_199 SVHLTDWVSESVLPADAALVAAMDEVRKVASTGSSLRKAKKLRVRLPLLK
******* . :* *. ** ** **.*.*..******:******** *
Mflv_3644|M.gilvum_PYR-GCK LTVAVQDPGRLEPYRDLIADELNVKAVELTDDIAAHGRFELAVNARVAGP
Mvan_2769|M.vanbaalenii_PYR-1 LTVAVEDPTRLEPYRELIADELNVKSVELTDDIAAHGRFELTVNARVAGP
MSMEG_3169|M.smegmatis_MC2_155 LTVAVQDPDSLRPFADLIADELNVKAVELSDDVPAYGRFELAVNARVAGP
TH_3715|M.thermoresistible__bu LTVGVDNPQRLEPFVDLIADELNVKSVELTDDIARYGRFELTVNARVAGP
Rv1536|M.tuberculosis_H37Rv LIVAVENPQLLRPFVDLIGDELNVKQVELTDAIDTYGRFELTVNARVAGP
Mb1563|M.bovis_AF2122/97 LIVAVENPQLLRPFVDLIGDELNVKQVELTDAIDTYGRFELTVNARVAGP
MLBr_01195|M.leprae_Br4923 LVVAVYNSQRLKPYIDLIGDELNVKQIELTDAIDTYGRFEFTVNARVAGP
MMAR_2356|M.marinum_M LTVAVENPQALKPFTDLIADELNVKQVELTDAIGTYGRFELTVNARVAGP
MUL_1532|M.ulcerans_Agy99 LTVAVENPQALKPFTDLIADELNVKQIELADAIGTYGRFELTVNARVAGP
MAV_3235|M.avium_104 LTVAVENPQHLAPFVDLIADELNVKSVELTDAIDTYGTFELTVNARVAGP
MAB_2705c|M.abscessus_ATCC_199 LTVAVPDPKRLEPYTALIADELNVKSVELTDDIAAYGKFELTVNARVAGP
* *.* :. * *: **.****** :**:* : :* **::********
Mflv_3644|M.gilvum_PYR-GCK RIGRDVQAAIKAVKAGEAVVNDDGTLTAGPAVLLPEEFSSKLVAAEE---
Mvan_2769|M.vanbaalenii_PYR-1 RIGKDVQAAIKAVKAGEAVVNADGTLTAGPAVLQPEEYSSRLVAADP---
MSMEG_3169|M.smegmatis_MC2_155 RIGKDVQAAIKAVKAGEGVVNPDGTLTAGPVVLQPEEYTSKLVAADP---
TH_3715|M.thermoresistible__bu RLGKDVQAAIKAVKAGEGVVNPDGTLTAGSVVLQPGEFSSRLVAADAPAD
Rv1536|M.tuberculosis_H37Rv RLGKDVQAAIKAVKAGDGVINPDGTLLAGPAVLTPDEYNSRLVAADP---
Mb1563|M.bovis_AF2122/97 RLGKDVQAAIKAVKAGDGVINPDGTLLAGPAVLTADEYNSRLVAADP---
MLBr_01195|M.leprae_Br4923 RLGRDVQAAIKVVKAGEGVANPDGTLTAGPVVLQPDEYSSRLVAANP---
MMAR_2356|M.marinum_M RLGKDVQAAIKAVKAGEGVVNSDGTLTAGPAVLQPEEYSSRLVAADP---
MUL_1532|M.ulcerans_Agy99 RLGKDVQAAIKAVKAGEGVVNSDGILTAGPAVLQPEEYSSRLVAADP---
MAV_3235|M.avium_104 RLGKDVQAAIKAVKAGEGVVNADGTLTAGPAVLRPEEYSSRLVAADP---
MAB_2705c|M.abscessus_ATCC_199 RLGKDVQTVIRAVKSGDWAQQADGTVVAAGITLREGEFDSKLVAAEP---
*:*:***:.*:.**:*: . : ** : *. .* *: *:****:
Mflv_3644|M.gilvum_PYR-GCK --AFTAALPGGAGLVVLDGTVTPELEAEGWAKDRIRELQELRKSTGLDVS
Mvan_2769|M.vanbaalenii_PYR-1 --EWTAALPDGAGLVVLDGTVTPELEAEGWARDMIREIQEFRRQCELDIS
MSMEG_3169|M.smegmatis_MC2_155 --EWTAALPDGAGLVVLDGTVTEELEAEGWAKDRIRELQELRKSTGLEVS
TH_3715|M.thermoresistible__bu EDRATAALPEGAGLVVLDCTVTPELEAEGWAKDRIRELQELRKSTGLDIS
Rv1536|M.tuberculosis_H37Rv --ESTAALPDGAGLVVLDGTVTAELEAEGWAKDRIRELQELRKSTGLDVS
Mb1563|M.bovis_AF2122/97 --ESTAALPDGAGLVVLDGTVTAELEAEGWAKDRIRELQELRKSTGLDVS
MLBr_01195|M.leprae_Br4923 --EFTAELPDGSGLVVLDDTVTPELEAEGWAKDRIRELQELRKLIGLDVS
MMAR_2356|M.marinum_M --EFTAALPGGAGLVVLDGTVTPELEAEGWAKDRIRELQELRKSTGLDVS
MUL_1532|M.ulcerans_Agy99 --EFTAALPSGAGLVVLDGTVTPELEAEGWAKDRIRELQELRKSTGLDVS
MAV_3235|M.avium_104 --EFTAALPNGAGLVVLDGTVTPELEAEGWAKDRIRELQELRKSTGLDVS
MAB_2705c|M.abscessus_ATCC_199 --DSTAALPEGGGLVILDDTVTEELEAEGWARDLIRELQDLRKSTGLEVS
** ** *.***:** *** ********:* ***:*::*: *::*
Mflv_3644|M.gilvum_PYR-GCK DRISVVMSVPSTHQQWAQTHRDLIAGEILATSFEFG---------EPDGA
Mvan_2769|M.vanbaalenii_PYR-1 DRILLELGVSELPEGWQEGLKDLIANEVLALELTINPELNLKLKVEPDDG
MSMEG_3169|M.smegmatis_MC2_155 DRISVRISVPAEHEQWARTHRDLIAGEILATSFEFA---------EVTDG
TH_3715|M.thermoresistible__bu DRISVVMSVPPQRQDWAERHRELIAGEILATSFEFGD--------PGESA
Rv1536|M.tuberculosis_H37Rv DRIRVVMSVPAEREDWARTHRDLIAGEILATDFEFA---------DLADG
Mb1563|M.bovis_AF2122/97 DRIRVVMSVPAEREDWARTHRDLIAGEILATDFEFA---------DLADG
MLBr_01195|M.leprae_Br4923 DRIRVLMSVPAERADWARVHRDFIAREILATSFEFG---------EPADS
MMAR_2356|M.marinum_M DRIQVLISVPGERAEWARTHRDLIAGEILATTFEFG---------EPDDG
MUL_1532|M.ulcerans_Agy99 DRIQVLISVPGERAEWARTHRDLIAGEILATTFEFG---------EPDDG
MAV_3235|M.avium_104 DRISVVMSVPAGRAEWAHTHRDLIAGEILATRFEFG---------EPADP
MAB_2705c|M.abscessus_ATCC_199 DRIEVVLEVPAVHRAWAERHRELISGEILATTLDIAEAG----ADTRTPA
*** : : *. * . :::*: *:** : :
Mflv_3644|M.gilvum_PYR-GCK TEIGDGVRVAIAKA------------------------
Mvan_2769|M.vanbaalenii_PYR-1 LDAQSGVVQATDDPNVFVGRVGRGYPVRLERVVAPSVH
MSMEG_3169|M.smegmatis_MC2_155 AEIGDGVRVEIAKV------------------------
TH_3715|M.thermoresistible__bu AEIGDGVRVAIAKAV-----------------------
Rv1536|M.tuberculosis_H37Rv VAIGDGVRVSIEKT------------------------
Mb1563|M.bovis_AF2122/97 VAIGDGVRVSIEKT------------------------
MLBr_01195|M.leprae_Br4923 VAIGDGVRVSLLKV------------------------
MMAR_2356|M.marinum_M VEIGDGVRVAIAKSGGAGVSGREQA-------------
MUL_1532|M.ulcerans_Agy99 VEIGDGVRVAIAKSGGAGVSGREQA-------------
MAV_3235|M.avium_104 VAIGDGVRVSISKV------------------------
MAB_2705c|M.abscessus_ATCC_199 TALSDGVRVSLKKAAG----------------------
.** .