For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VLIARPDILCSRGPEAMRAKAADLDLAAAAKTVGVQPAADQVAAAIAAILLSHAQIYQDISTQMAAFHDQ LVENRTADSTSYASAEANAQQSLLNAMDAPSWQQRRETVGEVGLPADPAGSGTATAAVAAATTARAGSRS AAQATVAPIGGLKLRRESALSQPGDLHHHVEVGDALPRVDPFQRGNVGVVAAYTHTDVLLGDLIVIGGVV VPPSTGPGLNPGMAAPVYRLSHHGITLRV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2408 | PE24 | - | 100% (239) | POSSIBLE PE FAMILY-RELATED PROTEIN |
| M. tuberculosis H37Rv | Rv1172c | PE12 | 2e-17 | 37.74% (159) | PE family protein |
| M. tuberculosis H37Rv | Rv0297 | PE_PGRS5 | 4e-16 | 37.16% (148) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2431 | PE24 | 1e-132 | 100.00% (239) | PE family-like protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4280 | - | 1e-17 | 36.67% (150) | PE family protein |
| M. avium 104 | MAV_1346 | - | 8e-09 | 27.60% (221) | PE family protein |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1019 | - | 1e-17 | 36.67% (150) | PE family protein |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4280|M.marinum_M MSYVAAVPEALTAAASDVAGIGTTISSANAAASAPTTGVLAAAGDQVSAQ
MUL_1019|M.ulcerans_Agy99 MSYVATVPEALTAAASDAAGIGTTISSANAAASAPTTGVLAAAGDQVSAQ
Rv2408|M.tuberculosis_H37Rv --MLIARPDILCSRG--PEAMRAKAADLDLAAAAKTVGVQPAA-DQVAAA
Mb2431|M.bovis_AF2122/97 --MLIARPDILCSRG--PEAMRAKAADLDLAAAAKTVGVQPAA-DQVAAA
MAV_1346|M.avium_104 MSFVTTRPEALLAVASMLEGLGSSMDAQNAAAAAPTTSIAPAAADEVSAL
: : *: * : . .: :. : **:* *..: .** *:*:*
MMAR_4280|M.marinum_M VAALFSSHGEIYQRLSSQLSTFHDQFAAALNTSANSYASAEAN-------
MUL_1019|M.ulcerans_Agy99 VAALFSSHGEIYQRLSSQLSTFHDQFAAALNTSANSYASAEAN-------
Rv2408|M.tuberculosis_H37Rv IAAILLSHAQIYQDISTQMAAFHDQLVENRTADSTSYASAEAN-------
Mb2431|M.bovis_AF2122/97 IAAILLSHAQIYQDISTQMAAFHDQLVENRTADSTSYASAEAN-------
MAV_1346|M.avium_104 QAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDTNADSYGATEAANRVNTSA
** : ::. ** :*:* ::*: :. :.: **.::**
MMAR_4280|M.marinum_M ------AAKTLLSAVNSPAEKLLGQPLMGQGGIVANAVSQVQSVFAGAGS
MUL_1019|M.ulcerans_Agy99 ------AAKTLLSAVNSPAEKLLGQPLMGQGGIVANAVSQVQSVFAGAGS
Rv2408|M.tuberculosis_H37Rv ------AQQSLLNAMDAPSWQQR-RETVGEVGLPADPAG------SGTAT
Mb2431|M.bovis_AF2122/97 ------AQQSLLNAMDAPSWQQR-RETVGEVGLPADPAG------SGTAT
MAV_1346|M.avium_104 AALQGLAPNVIPNAAPAADPPPAGTTSLGTSIGWAQNVGAAASDFITLGE
* : : .* :. :* *: .. .
MMAR_4280|M.marinum_M NALGANASMLALAPTGGAATAAASGSLLGPIASAAAAPAAILP-VSVATA
MUL_1019|M.ulcerans_Agy99 NALGANASMLALAPTGGAATAAASGSLLGPIASAAAAPAAILP-VSVATA
Rv2408|M.tuberculosis_H37Rv AAVAAATTARAGSRSAAQATVAPIGGLKLRRESALSQPGDLHHHVEVGDA
Mb2431|M.bovis_AF2122/97 AAVAAATTARAGSRSAAQATVAPIGGLKLRRESALSQPGDLHHHVEVGDA
MAV_1346|M.avium_104 GQFAPVPGAAGIPNFNPGLTAATTAGPPAPAAPAAAAGAPVLASMGRGPS
... . . . *.*. .. .* : . : : . :
MMAR_4280|M.marinum_M IQNFYLAVEPWVQYGFNLASWAVGWVPWIGILAPQINFFYYLFEPIVQSG
MUL_1019|M.ulcerans_Agy99 IQNFCLAVEPWVQYGFNLASWAVGWVPWIGILAPQINFFYYLFEPIVQSG
Rv2408|M.tuberculosis_H37Rv LP----RVDPFQRG-------------NVGVVAAYTHTDVLLGDLIVIGG
Mb2431|M.bovis_AF2122/97 LP----RVDPFQRG-------------NVGVVAAYTHTDVLLGDLIVIGG
MAV_1346|M.avium_104 IGG--LSVPPSWAPG--------GVAPAANATPAQLVGAGFTSAAPDTAP
: * * . .. .
MMAR_4280|M.marinum_M LFNTLDWLDGTITFSQGLS-------NFWSATTASVNQFIQTEINWIRHF
MUL_1019|M.ulcerans_Agy99 LFNTLDWLDGTVTFSQGLSNFSQGLSNFWSATTASVNQFIQTEINWIRNF
Rv2408|M.tuberculosis_H37Rv VVVPP-------STGPGLN----------PGMAAPVYRLSHHGITLRV--
Mb2431|M.bovis_AF2122/97 VVVPP-------STGPGLN----------PGMAAPVYRLSHHGITLRV--
MAV_1346|M.avium_104 VTAVPGGVPSMATAGRGGY-----------GLGAPRYGVKPTVMPKPAI-
: : . * . *. . :
MMAR_4280|M.marinum_M FPPFPPLPF
MUL_1019|M.ulcerans_Agy99 FPPFPPLPF
Rv2408|M.tuberculosis_H37Rv ---------
Mb2431|M.bovis_AF2122/97 ---------
MAV_1346|M.avium_104 ---------