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M. tuberculosis H37Rv Rv2331 (-)

annotation: hypothetical protein Rv2331
coordinates: 2604297 - 2604683
length: 128

VPPVFLPQIGRLTPDAVGEAIGIAADDIPMAARWIGSRPCSLIGQPNTMGDEMGYLGPGLAGQRCVDRLV
MGASRSTCSRLPVIASVDERLSVLKPVRPRLHSISFIFKGRPGEVYLTVTGYNFRGVP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2331--100% (128)hypothetical protein Rv2331

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2358-5e-72100.00% (128) hypothetical protein Mb2358
M. gilvum PYR-GCKMflv_3016-1e-0668.75% (32) molybdopterin oxidoreductase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2438-3e-0736.17% (94) oxidoreductase
M. marinum MMMAR_3639fdhF9e-1165.31% (49) formate dehydrogenase H FdhF
M. avium 104MAV_2075-1e-0857.69% (52) FdhF protein
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_1474fdhF6e-1165.31% (49) formate dehydrogenase H FdhF
M. vanbaalenii PYR-1Mvan_3491-7e-0771.88% (32) molybdopterin oxidoreductase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3016|M.gilvum_PYR-GCK          ------MTRTACSYCGVGCGISVETRTDP-ASGVPVIARVSGDKLHPTNF
Mvan_3491|M.vanbaalenii_PYR-1       ------MTRTACSYCGVGCGISVETRTDP-ATGVPVIARVTGDKLHPSNF
MAB_2438|M.abscessus_ATCC_1997      ------------------------MRTDAHAAGPVTVATVEGDVLHPSNQ
MAV_2075|M.avium_104                -------MNTMCAYCGVGCGMVLQITTDP-QTGRRHVAKSVGNKEHPANF
MMAR_3639|M.marinum_M               MAPNKDAVKTVCAYCGVGCGIVLQTTTDP-QTGKRRVAKSTGDKSHPANL
MUL_1474|M.ulcerans_Agy99           MAPNKDAVKTVCAYCGVGCGIVLQTTTDP-QTGKRRVAKSTGDKSHPANL
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          GRLCTKGATHAEMMAATDGRLTTALVRPSRDADPVALDVDDAVAEAGSRL
Mvan_3491|M.vanbaalenii_PYR-1       GRLCTKGATHAEMMAATDGRLTTALLRPSRDAEPVATDVDDALAEAGARL
MAB_2438|M.abscessus_ATCC_1997      GRLCTKGATHAQLMAA-DGRMTTAHLRSIRGQQPIPAPLAAATAEAGRRL
MAV_2075|M.avium_104                GRLCTKGATTADLLAA-PGRMDSAHARAGRGEPLEPIGTDQAITRCAKQL
MMAR_3639|M.marinum_M               GRLCTKGTTTADLLAA-PGRMESAHLRAHRAGHLESIPIDDAITQCAMRL
MUL_1474|M.ulcerans_Agy99           GRLCTKGTTTADLLAA-PGRMESAHLRAHRAGHLESIPIDDAITQCAMRL
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          RAIVDEHGPDAVALYVSGQMSIEAQYLATKLAKGFLRTVHIESNSRLCMA
Mvan_3491|M.vanbaalenii_PYR-1       RAILDEHGPDAVALYVSGQMSIEAQYLATKLAKGFLRTVHIESNSRLCMA
MAB_2438|M.abscessus_ATCC_1997      REILDNHGPDAIALYVSGQMTLEAQYLANKLAKGYIRTTHIESNSRLCMA
MAV_2075|M.avium_104                RAIIDEHGPDAFAMYVSGQMSLEAQYLANKLTKGFIGTNQIESNSRLCMA
MMAR_3639|M.marinum_M               RAIIDEHGPDAVGVYVSGQMSIEAQYLANKLTKGFIGTNQIESNSRLCMA
MUL_1474|M.ulcerans_Agy99           RAIIDEHGPDAVGVYVSGQMSIEAQYLANKLTKGFIGTKQIESNSRLCMA
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          SAGTGYKQSLGSDGPPGSYTDFDCTNLFFVIGSNMADCHPILYLRMADRL
Mvan_3491|M.vanbaalenii_PYR-1       SAGTGFKQSLGADGPPGSYTDFDCTDLFFVIGSNMADCHPILYLRMADRL
MAB_2438|M.abscessus_ATCC_1997      SAGTGYAQSLGADGPPGSYSDIEHSDLFFVIGANMADCHPILFLRMADRL
MAV_2075|M.avium_104                SAGSGYKLSLGADGPPGSYQDFEHADVFFVIGANMADCHPILFLRMMDRV
MMAR_3639|M.marinum_M               GASSGYKLSLGADGPPGSYQDFDHADVFLVIGANMADCHPILFLRMMERV
MUL_1474|M.ulcerans_Agy99           GASSGYKLSLGADGPPGSYQDFDHADVFLVIGANMADCHPILFLRMMERV
Rv2331|M.tuberculosis_H37Rv         --------------------------------------MPPVFLPQIGRL
Mb2358|M.bovis_AF2122/97            --------------------------------------MPPVFLPQIGRL
                                                                           * ::*    *:

Mflv_3016|M.gilvum_PYR-GCK          KAGARLIVVDPRRTATADKADLYLPIRPGTDLALLNGILRVLVQDGAIDE
Mvan_3491|M.vanbaalenii_PYR-1       KAGAKLIVVDPRRTATADKADLYLPIRPGTDLALLNGILHLLVENGAVDQ
MAB_2438|M.abscessus_ATCC_1997      SSGARLIVVDPRRTATADRADLFLQITPGTDLALLNGLLHLLVENGAVDA
MAV_2075|M.avium_104                KAGAKLIVVDPRRTATAEKADLFLQIAPGTDLALLNGLLHLIVENGHTDG
MMAR_3639|M.marinum_M               KSGAKLIVVDPRRTATADKADLFLQIAPGTDLALLNGLLHLIVENEQTDP
MUL_1474|M.ulcerans_Agy99           KSGAKLIVVDPRRTATADKADLFLQIAPGTDLALLNGLLHLIVENEQTDP
Rv2331|M.tuberculosis_H37Rv         T-------------------------------------------------
Mb2358|M.bovis_AF2122/97            T-------------------------------------------------
                                    .                                                 

Mflv_3016|M.gilvum_PYR-GCK          AFIAEHTEGWEAMPAFLADYPPSRVAEITGLAEADIRSAAAMIAEAGDWI
Mvan_3491|M.vanbaalenii_PYR-1       EFIAEHTQGWESMPEFLAGYPPDRVAAITGLSEADIRAAADMIAEAGDWL
MAB_2438|M.abscessus_ATCC_1997      EFIAQHTEGWDGMPEFLAGYAPAVVAAITGLAEEDIRTAARWIGEAREWM
MAV_2075|M.avium_104                EFIAEFTEGWEVMPSFLEQYTPDRVSEITGIPEQDIRAAAQLIGEADNFM
MMAR_3639|M.marinum_M               QFISEFTEGWEVMPSFLEQFTPDRVSEITGIPSEDIRTAARWIGTAANWM
MUL_1474|M.ulcerans_Agy99           QFISEFTEGWEVMPSFLEQFTPDRVSEITGIPSEDIRTAARWIGTAANWM
Rv2331|M.tuberculosis_H37Rv         ---------------------PDAVGEAIGIAADDIPMAARWI-------
Mb2358|M.bovis_AF2122/97            ---------------------PDAVGEAIGIAADDIPMAARWI-------
                                                         *  *.   *:.  **  **  *       

Mflv_3016|M.gilvum_PYR-GCK          SCWTMGLNQSTHGTWNTNAICNLHLATGAICRPGAGPMSLTGQPNAMGGR
Mvan_3491|M.vanbaalenii_PYR-1       SCWTMGLNQSTHGTWNTNAICNLHLATGAICRPGSGPMSLTGQPNAMGGR
MAB_2438|M.abscessus_ATCC_1997      TLWTMGLNQSTHGTWNTNAICNLHLATGAICRPGSGPFSLTGQPNAMGGR
MAV_2075|M.avium_104                SCWTMGLNQSTHGTWNTNAICNLHLATGAICKPGSGPFSLTGQPNAMGGR
MMAR_3639|M.marinum_M               SCWTMGLNQSTHGTWNTNALCNLHLATGAICRPGSGPFSLTGQPNAMGGR
MUL_1474|M.ulcerans_Agy99           SCWTMGLNQSTHGTWNTNALCNLHLATGAICRPGSGPFSLTGQPNAMGGR
Rv2331|M.tuberculosis_H37Rv         ---------------------------------GSRPCSLIGQPNTMG-D
Mb2358|M.bovis_AF2122/97            ---------------------------------GSRPCSLIGQPNTMG-D
                                                                     *: * ** ****:**  

Mflv_3016|M.gilvum_PYR-GCK          EMGYMGPGLPGQRAVLSAEDRSFVETQWDLEPGTVRTEVGPGTVEMFRRI
Mvan_3491|M.vanbaalenii_PYR-1       EMGYMGPGLPGQRSVASAADRAFVEEQWDLEPGTIRADIGPGTVEMFRQM
MAB_2438|M.abscessus_ATCC_1997      EMGYMGPGLPGQRSVKSPADRDFVEKRWQLPPGSIRAEFGTGTVDMFAQM
MAV_2075|M.avium_104                EMGYMGPGLPGQRSVASAADREFVEDVWGVPRGRLRTEVGTGTIDMFSRM
MMAR_3639|M.marinum_M               EMGYMGPGLPGQRSVLSAPDREFVEEQWGLPGGALRTDVSGGVIDMFSRM
MUL_1474|M.ulcerans_Agy99           EMGYMGPGLPGQRSVLSAPDREFVEEQWGLPGGALRTDVSGGVIDMFSRM
Rv2331|M.tuberculosis_H37Rv         EMGYLGPGLAGQR----CVDR--------LVMGASRSTCS--------RL
Mb2358|M.bovis_AF2122/97            EMGYLGPGLAGQR----CVDR--------LVMGASRSTCS--------RL
                                    ****:****.***      **        :  *  *:  .        ::

Mflv_3016|M.gilvum_PYR-GCK          AGGDIKAVWIICTNPVASVANRDTVITGLQSAELVITQDAYVDTATNRYA
Mvan_3491|M.vanbaalenii_PYR-1       GSGDIKAAWIICTNPVASVANRDAVVAGLSTAELVITQDVYADTATNRYA
MAB_2438|M.abscessus_ATCC_1997      AAGNIKACWIICTNPVASVANRKNVVDGLRRAELVIAQDAFLATATNEYA
MAV_2075|M.avium_104                ADGQIKACWIICTNPVASVANRKTVLAGLERAELVIAQDAYLGTETSEYA
MMAR_3639|M.marinum_M               ADGEIKACWIICSNPVATVANRKTVLAGLEKAELVISQDAFFETETNEYA
MUL_1474|M.ulcerans_Agy99           ADGEIKACWIICSNPVATVANRKTVLAGLEKAELVISQDAFFETETNEYA
Rv2331|M.tuberculosis_H37Rv         P-------------VIASVDERLSVLK-----------------------
Mb2358|M.bovis_AF2122/97            P-------------VIASVDERLSVLK-----------------------
                                                   :*:* :*  *:                        

Mflv_3016|M.gilvum_PYR-GCK          DIMLPATLWAEADAVMVNSGRTLTLLAQSVPAAGDARPDWELICGVARHL
Mvan_3491|M.vanbaalenii_PYR-1       DIVLPATLWAETDAVMVNSDRNLTLLQQSVPPVGDARPDWELICGVARHL
MAB_2438|M.abscessus_ATCC_1997      DILLPAALWAESDGVSINSERTATLTNRAVEAPGDARPDWQLICDIATAM
MAV_2075|M.avium_104                DVLLPAALWAETEGVMVNSERNITLSQPAVAAPGGAMPDWQIIARIACEM
MMAR_3639|M.marinum_M               NVLLPAALWTESDGVMVNCERNMSLFPKAVDPVGDALPDWQIIARIACEM
MUL_1474|M.ulcerans_Agy99           NVLLPAALWTESDGVMVNCERNMSLFPKAVDPVGDALPDWQIIARIACEM
Rv2331|M.tuberculosis_H37Rv         ----------------------------------PVRPRLHSIS------
Mb2358|M.bovis_AF2122/97            ----------------------------------PVRPRLHSIS------
                                                                       . *  . *.      

Mflv_3016|M.gilvum_PYR-GCK          GFGDAFDHKSSEEIFDEIRRFHNPRTGYDLRGVTYERLRATPVQWPCPSE
Mvan_3491|M.vanbaalenii_PYR-1       GFGDAFDYKSSEQIFDEIRRFHNPGTGYDLRGITYERLRDTPVQWPCASA
MAB_2438|M.abscessus_ATCC_1997      GFGDAFGYSSSEEIFEEIRAFWNPRTGYDMRGMSYARLRQGPVQWPCPPE
MAV_2075|M.avium_104                GFSEAFSYSCAEEVFEEIKRFWNPTTGYDLRGVSYERLRRQPLQWPCPPQ
MMAR_3639|M.marinum_M               GFSESFSYSSAAEVFEEIKRFSNPATGYDLRGISHDRLRETPLQWPCPPD
MUL_1474|M.ulcerans_Agy99           GFSESFSYSSAAEVFEEIKRFSNPATGYDLRGISHDRLRETPLQWPCPPD
Rv2331|M.tuberculosis_H37Rv         -----FIFKGRP------GEVYLTVTGYNFRGVP----------------
Mb2358|M.bovis_AF2122/97            -----FIFKGRP------GEVYLTVTGYNFRGVP----------------
                                         * ..           .  . ***::**:.                

Mflv_3016|M.gilvum_PYR-GCK          DAPDRNPIRYLNDGVSQDLHIDDDGHIPRLAFATPSRRAVFHPRPHLDAA
Mvan_3491|M.vanbaalenii_PYR-1       EQSDRNPIRYLNDGVSQDQYVGPDGHRPRLAFPTPSRRAVFHPRPHMDAA
MAB_2438|M.abscessus_ATCC_1997      SEVDRNPIRYLNDGISQHPHVDENGVVPRLAFPTPSRRAVFHARAHRDPA
MAV_2075|M.avium_104                STADRNPIRYLNDGVSQTQLVREDGTVPRLAFPTPSGRAVFFARPHLQPE
MMAR_3639|M.marinum_M               GASNRSPIRYLNDGVSQLQFVRADGTVPRLAFPTATGRAVFFARPHLVPD
MUL_1474|M.ulcerans_Agy99           GASNRSPIRYLNDGVSQLQFVRADGTVPRLAFPTATGRAVFFARPHLVPD
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          ELPDDDYPFILNTGRLQHQWHTMTKTGRVAKLTKLNPAPFVEIHPSDAAA
Mvan_3491|M.vanbaalenii_PYR-1       ELPDDDYPLVLNTGRLQHQWHTMTKTGKVAKLNKLNPGPFVEIHPDDAAA
MAB_2438|M.abscessus_ATCC_1997      ELPGEGYPVVLNTGRLQHHWHTLTKTGRIKTLDRLHPSPFVEIHPHDATT
MAV_2075|M.avium_104                EMPDDDYPFLLNTGRLPHQWHTMTKTGKVAKLNKLNPGPFVEIHPDDAAR
MMAR_3639|M.marinum_M               EMPDGDYPFLLNTGRLAHQWHTLTKTGKIAKLNKLNPGPFVEVHPDDAAD
MUL_1474|M.ulcerans_Agy99           EMPDGDYPFLLNTGRLAHQWHTLTKTGKIAKLNKLNPGPFVEVHPDDAAD
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          LGITDGQDLELRTRRGRAVLPAVLTERVRPGNTWAPFHWNDEHGENLTIN
Mvan_3491|M.vanbaalenii_PYR-1       LGISGGHDVELVTRRGRAVLPAVLTDRVQPGNTWVPFHWNDEHGDHLTVN
MAB_2438|M.abscessus_ATCC_1997      LGISDGDIVEIASRRGTAELPALVSDRVKRGSCFAPFHWNDAHGPGLTIN
MAV_2075|M.avium_104                LGIGEHDRVEIASRRGRAVLPAVVSDRVRPGNCFAPFHWNDAFGEYLSIN
MMAR_3639|M.marinum_M               MQICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFHWNDAFGEYLSIN
MUL_1474|M.ulcerans_Agy99           MQICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFHWNDAFGEYLSIN
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          ALTNDAVDPDSLQPEFKVCAVRLTPVPAADG-------------------
Mvan_3491|M.vanbaalenii_PYR-1       ALTNDAVDPDSLQPEFKVCAVRLAPVPAAG--------------------
MAB_2438|M.abscessus_ATCC_1997      AVTNDAVDPDSLQPEFKVSAVALRPT------------------------
MAV_2075|M.avium_104                AVTNDAVDPISNQPEFKACAVTLTKVAVSHPDSAIG-TGPSAGHDTPESA
MMAR_3639|M.marinum_M               AVTNDAVDPISRQPEYKACAVTLTKVARPQLQPEPGEPADTCADATAPKL
MUL_1474|M.ulcerans_Agy99           AVTNDAVDPISRQPEYKACAVTLTKVARPQLQPEPGEPADACADATAPKL
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          -------------------------APDLTDDEKLYIAGFLAGVDEGR--
Mvan_3491|M.vanbaalenii_PYR-1       -------------------------APEFTETEKLYLAGFFAGIEEGL--
MAB_2438|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_2075|M.avium_104                PTEVREISVSQVDALGELLGVATSFKPEFNELGRSYLAGMLTGLRSDVGR
MMAR_3639|M.marinum_M               LADTAQFSVTQVDALAELLGVANEPTPQFGPFARSYLAGLIAGLRSETGR
MUL_1474|M.ulcerans_Agy99           LADTAQFSVTQVDALAELLGVGNEPTPQFGPSARSYLAGLIAGLRSETGR
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          --PGVPVLPAGAPVGARARLWVDGLLAGRYSRLETAAPSAS---------
Mvan_3491|M.vanbaalenii_PYR-1       --PGVPVLPASAPVGPRARLWVDGLLAGRYSRSDTVAETPA---------
MAB_2438|M.abscessus_ATCC_1997      ---------------------------GRTKADSMPEKQKE---------
MAV_2075|M.avium_104                RAGGVPTLPPSAPFDSRTRLWVDGLLAGLFSRADASQQAALPEPPQPAAQ
MMAR_3639|M.marinum_M               RMAGVPTLPVSSPFDTGTRLWLDGLLAGMFARAETPPALPFPQTPG----
MUL_1474|M.ulcerans_Agy99           RMAGVSTLPISSPFDTGTRLWLDGLLAGMFARAETPPALPFPQTPG----
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          -------------PRGGPLVLWASQTGTAEEFAGSLGERLA----GARLR
Mvan_3491|M.vanbaalenii_PYR-1       -------------TEG-PLVLWASQTGNAEEFAGRLGERLN----GARLR
MAB_2438|M.abscessus_ATCC_1997      -------------ALGDVAILWTSQTGNAETAAVSVHRLLHTAGISATIT
MAV_2075|M.avium_104                QPPAAPAGATPAPERAPVVVLWASQTGNAEELAADVAAQLAAAELPVALH
MMAR_3639|M.marinum_M               AAAQSDNAAEAAVEQPPIVVLWASQTGTAEELAASVAAQLSAAELPVVLH
MUL_1474|M.ulcerans_Agy99           AAAQSDNAAEAAVEQPPIVVLWASQTGTAEELAASVAAQLSAAELPVVLH
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          AMDDTDLSELSDAGEVVIVTSTFGDGGPPDNGTAFWERLESADAPALDGV
Mvan_3491|M.vanbaalenii_PYR-1       AMDDVELDDLSEAGEVVIVTSTFGDGGPPDNGAGFWERLESPHAPSLDGV
MAB_2438|M.abscessus_ATCC_1997      AMDECDPADLVGVNTAVVIASSFGEGGPPDNGARFWAALSGDTKP-LNHM
MAV_2075|M.avium_104                SMDDFPAAELAATRELLLITSTTGDGDAPDNGSGLWRALTGDAAPRLGNT
MMAR_3639|M.marinum_M               GMDEFAVADLVSTQRLLLVTSTTGDGEPPDNGAAFWRELCAATAPSLAGT
MUL_1474|M.ulcerans_Agy99           GMDEFAVADLVSTQRLLLVTSTTGDGEPPDNGAAFWRELCAPTAPSLAGT
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          RYTVLGIGDRSYDNFCGHAKSLDTRLADLGATRMLDRADCEAYDEQPMAA
Mvan_3491|M.vanbaalenii_PYR-1       RYTVLGIGDRSYDNFCGHARSLDARLADLGATRMLDRVECEAYDAQPLAR
MAB_2438|M.abscessus_ATCC_1997      RYAVLGFGDRAYADFCGHAKALDARLHELGASPLLGRVDGEATDRTLVAS
MAV_2075|M.avium_104                RYAVLALGDSNYDDFCGHGRKLDARLAELGATRIAERVDCEPDYEQAAAK
MMAR_3639|M.marinum_M               RYSVLALGDSNYADFCGHGRALDHRLAELGASRVTDRVDCEPDYEESAAR
MUL_1474|M.ulcerans_Agy99           RYSVLALGDSNYADFCGHGRALDHRLAELGASRITDRVDCEPDYEESAAR
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          WADSVVGLMS---------TPVTPAPT-------QPAVPAAPAPFTRGNP
Mvan_3491|M.vanbaalenii_PYR-1       WADSVVELVA---------APGTPP----------AAPAQEPTLFTRAEP
MAB_2438|M.abscessus_ATCC_1997      WTADLLDAIG---------DGATAIVETVRKLRSEGLRVAAPERFTRDAP
MAV_2075|M.avium_104                WVADVIEALTRTPTAVGGDGGATVSARTSPVAAPSRPNTPAPHTYSKKHP
MMAR_3639|M.marinum_M               WLQEVLDGLR-----------RTAPPVITAAPVRAASIANRPQGYTKKRP
MUL_1474|M.ulcerans_Agy99           WLQEVLDGLR-----------RTAPPVITAEPVRAASIASRPQGYTKKRP
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          AQAPLCRNVRLTPDGAGKDVRQFGFDISGQDLAYSVGDSLGVWVVNSDAV
Mvan_3491|M.vanbaalenii_PYR-1       VAAPLCRNTRLTPQGAAKEVRQIGFDISAHDVTYSVGDSLGVCVVNSDFV
MAB_2438|M.abscessus_ATCC_1997      ILAALSHNELLSAPNSGKEVRRIEFDLTGHDVSYSAGDALGIYPTNREED
MAV_2075|M.avium_104                LITDMVRNTTLNGPKSTKDVRHLVFNLPEDAVSYEAGDALGVWPRNSDEL
MMAR_3639|M.marinum_M               LLTSVMRNTTLSRPRSAKDVRQLVFRVPEQTVSYEAGDALGVWPRNAHQL
MUL_1474|M.ulcerans_Agy99           LLTSVMRNTTLSRPRSAKDVRQLVFRVPEQTVSYEAGDALGVWPRNAHQL
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          VESWLSATGFHGAEAVIVDGR-QISLREALTRHYDVCKVTSNLVTFVAEH
Mvan_3491|M.vanbaalenii_PYR-1       VENWLAATDLRGDEAVVVDGV-QQALRDALTAHYDVCKVTSNLVKFVAEH
MAB_2438|M.abscessus_ATCC_1997      VQRWLTTTGFDAQLPVTIDGG-ELPLATALANHYDICRVTEDLLRFIAER
MAV_2075|M.avium_104                VDEWLAVTGLDGQTPVEVGEHGLMSLRSALTERIEIAHISRDLVRFVQER
MMAR_3639|M.marinum_M               VDEWLGVTQLDGHTEVEVAGHGTMSLRAALTDRFEIAHLSPDLLRFVAQR
MUL_1474|M.ulcerans_Agy99           VDEWLGVTRLDGHTEVEVAGHGTMSLRAALTDRFEIAHLSPDLLRFVAQR
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          CPDA----ATAKRLRN-DRGALDTWLVDRNGLDLVREFGIRADPALWQEV
Mvan_3491|M.vanbaalenii_PYR-1       CRDA----ATAKRLRN-DRGELDRWLVNRNGLDLVREFSVRADPQLWQEV
MAB_2438|M.abscessus_ATCC_1997      RRDK----HSAKLLQGRDTQAREVWLRGRNALDVIREFPIRAAIEEWQQV
MAV_2075|M.avium_104                TGDA----KLAELLKPENKRALADWTWGRQSIDLLAQLPVSASAHEWLRV
MMAR_3639|M.marinum_M               TLDSNTANQLAELMRPENKAALADWTWGRQSVDLLAQSPVRASVDEWMSV
MUL_1474|M.ulcerans_Agy99           TLDSNTANQLAELMRPENKAALADWTWGRQSVDLLAQSPVRASVDEWMSV
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          LVRLTPRQYSISSSPLVSPHEVQLTVSVVRYRGADGTPRGGVASTYLADL
Mvan_3491|M.vanbaalenii_PYR-1       LVRLTPRQYSISSSPLVSPNEVQLTVSVVRYRGADGGPRGGVASTYLADL
MAB_2438|M.abscessus_ATCC_1997      LIRLTPRQYSISSSPLVSPQAISLTVSIVRYQGPDGSPRGGVGSTFLADR
MAV_2075|M.avium_104                LKRLQPRLYSISSSPKACPGEVHLTVSPVRYN-FQGVPRRGVCSTYLAAR
MMAR_3639|M.marinum_M               LKPIQPRLYSISSSPKEHPGEVHLTVSPVRYN-FQGVPRRGVCSTYLADR
MUL_1474|M.ulcerans_Agy99           LKPIQPRLYSISSSPKEHPGEVHLTVSPVRYN-FQGVPRRGVCSTYLADR
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          PDCTPVPVFLQRSPHFRPPEDPHTPMIMVGPGTGIAPFRGFLQERRALGH
Mvan_3491|M.vanbaalenii_PYR-1       PDGTAVPVFLQRSPHFRPPQDSHTPMIMVGPGTGIAPFRGFLQERRALGH
MAB_2438|M.abscessus_ATCC_1997      AQHLPVPIFLQRSPHFRPPRTSDTPMIMIGPGTGIAPFRGFLQERRALGH
MAV_2075|M.avium_104                SPGDRVAVYLQPSSNFRPPSDPDTPMIMIGPGTGIAPFRGFLQERRALGH
MMAR_3639|M.marinum_M               SPSDQIAIYVRKSSNFRPPSDPRTPMIMIGPGTGIAPFRGFLQERRALGH
MUL_1474|M.ulcerans_Agy99           SPSDQIAIYVRKSSNFRPPSDPRTPMIMIGPGTGIAPFRGFLQERRALGH
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          RGANWLFFGDQHREQNFYYRDDLLDMVDDGFLNRLDLAFSRDQRQRIYVQ
Mvan_3491|M.vanbaalenii_PYR-1       RGPNWLFFGDQHRAQNFYYRDDLQDMVDDGFLNRLDLAFSRDQARRVYVQ
MAB_2438|M.abscessus_ATCC_1997      TGANWLFFGDQHRTEHFYYRDELDGFLRDGSLRRLDLAFSRDQAKRIYVQ
MAV_2075|M.avium_104                RGPNWLFFGEQHAATDFYYRDELEQMREDGFLTELDLAFSRDQQHKVYVQ
MMAR_3639|M.marinum_M               TGPNWLFFGEQHAATDFYYRDEIQAMHRDGLLTNLDLAFSRDQRDKVYVQ
MUL_1474|M.ulcerans_Agy99           TGPNWLFFGEQHAATDFYYRDEIQAMHRDGLLTNLDLAFSRDQRDKVYVQ
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          HKMLDYGADVWRWLDDGAHFYVCGDATRMAKDVDDALTEILRTHARMSSD
Mvan_3491|M.vanbaalenii_PYR-1       HKMLDYGADVWRWLDDGAHFYVCGDATRMAGDVDDALTEIIRTHGGMSAD
MAB_2438|M.abscessus_ATCC_1997      HRMMEQGAQLWRWLNEGAHLYVCGDASRMAKDVDGALLTIAQKHGKLSGE
MAV_2075|M.avium_104                HLMRNRGKQLWSWLQDGAQLYVCGTADPMAKDVDRALCDIAAEFGNLDPD
MMAR_3639|M.marinum_M               HLMQQRGAQLWQWLQDGAQVYVCGTADPMAKDVDRMLCQIVAEHGGLDPE
MUL_1474|M.ulcerans_Agy99           HLMQQRGAQLWQWLQDGAQVYVCGTADPMAKDVDRMLCQIVAEHGGLDPE
Rv2331|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2358|M.bovis_AF2122/97            --------------------------------------------------
                                                                                      

Mflv_3016|M.gilvum_PYR-GCK          AAREYKREMVAEKRYVRDVY
Mvan_3491|M.vanbaalenii_PYR-1       AARDYKREMVAEKRYVRDVY
MAB_2438|M.abscessus_ATCC_1997      QALEFRKELVAEKRYVRDVY
MAV_2075|M.avium_104                AAKAYVQSLSADKRYHRDVY
MMAR_3639|M.marinum_M               SATAFVHALSADKRYHRDVY
MUL_1474|M.ulcerans_Agy99           SATAFVHALSADKRYHRDVY
Rv2331|M.tuberculosis_H37Rv         --------------------
Mb2358|M.bovis_AF2122/97            --------------------