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RQILIAVAVAVTVSILLTPVLIRLFTKQGFGHQIREDGPPSHHTKRGTPSMGGVAILAGIWAGYLGAHLA GLAFDGEGIGASGLLVLGLATALGGVGFIDDLIKIRRSRNLGLNKTAKTVGQITSAVLFGVLVLQFRNAA GLTPGSADLSYVREIATVTLAPVLFVLFCVVIVSAWSNAVNFTDGLDGLAAGTMAMVTAAYVLITFWQYR NACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNAAPAKIFMGDTGSLALGGVIAGLSVTSRTEIL AVVLGALFVAEITSVVLQILTFRTTGRRMFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFYG EWLAAVGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2156c | mraY | - | 100% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. tuberculosis H37Rv | Rv1302 | rfe | 2e-20 | 29.36% (327) | undecapaprenyl-phosphate |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2180c | mraY | 0.0 | 100.00% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. gilvum PYR-GCK | Mflv_2985 | mraY | 0.0 | 86.07% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. leprae Br4923 | MLBr_00911 | mraY | 0.0 | 90.81% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. abscessus ATCC 19977 | MAB_2003 | mraY | 1e-171 | 80.17% (358) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. marinum M | MMAR_3196 | mraY | 0.0 | 92.48% (359) | phospho-N-acetylmuramoyl- pentappeptidetransferase MurX |
| M. avium 104 | MAV_2333 | mraY | 0.0 | 89.69% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. smegmatis MC2 155 | MSMEG_4230 | mraY | 0.0 | 87.19% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. thermoresistible (build 8) | TH_1328 | - | 1e-180 | 85.24% (359) | Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX |
| M. ulcerans Agy99 | MUL_3504 | mraY | 0.0 | 92.20% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. vanbaalenii PYR-1 | Mvan_3526 | mraY | 0.0 | 86.91% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2985|M.gilvum_PYR-GCK MRQILIAVAIALAVAILLTPVLIRLFTRQGFGHEIREDGPPSHHKKRGTP
Mvan_3526|M.vanbaalenii_PYR-1 MRQILIAVAIAVAVSILLTPVLIRLFTRQGFGHEIREDGPPSHHKKRGTP
TH_1328|M.thermoresistible__bu MRQILIAAGIALAVSILLTPALIRLFTRQGFGHEIREDGPPSHHKKRGTP
MSMEG_4230|M.smegmatis_MC2_155 MMLILIAVGIALAVSILLTPALIRLFTKQGLGHEIREDGPPSHAKKRGTP
Rv2156c|M.tuberculosis_H37Rv MRQILIAVAVAVTVSILLTPVLIRLFTKQGFGHQIREDGPPSHHTKRGTP
Mb2180c|M.bovis_AF2122/97 MRQILIAVAVAVTVSILLTPVLIRLFTKQGFGHQIREDGPPSHHTKRGTP
MMAR_3196|M.marinum_M MRQIMIAVAIAVAVSILLTPALIRLFTKQGFGHQIREDGPPSHHSKRGTP
MUL_3504|M.ulcerans_Agy99 MRQIMIAVAIAVAVSILLTPALIRLFTKQGFGHQIREDGPPSHHSKRGTP
MLBr_00911|M.leprae_Br4923 MRQILVAVTVALVVSILLTPALIRLFTRHGFGQEIREDGPPSHHNKRGTP
MAV_2333|M.avium_104 MRQILIAVAIALTVSILLTPALIRLFTRQGFGHHTREDGPPTHHAKRGTP
MAB_2003|M.abscessus_ATCC_1997 MRQIIIAAGIAILVSIMLTPVLIRVFSRQGFGQEIRDDGPQHHQKKRGTP
* *::*. :*: *:*:***.***:*:::*:*:. *:*** * *****
Mflv_2985|M.gilvum_PYR-GCK SMGGVAIIAGIWVSYFGTHLVGVLMDGKGPSASGLLVLGLATSLGVVGFL
Mvan_3526|M.vanbaalenii_PYR-1 SMGGVAIVAGIWASYFGTHLVGVVIDGKGPSASGLLVLGLATALGAVGFL
TH_1328|M.thermoresistible__bu SMGGVAILAGMWASYLGTHLVGIALDGRGPSASGLLVLGLATALGLVGFI
MSMEG_4230|M.smegmatis_MC2_155 SMGGVAILAGIWAGYLGSHLVGMAMGGDGPSASGLLVLGLATVLGGVGFI
Rv2156c|M.tuberculosis_H37Rv SMGGVAILAGIWAGYLGAHLAGLAFDGEGIGASGLLVLGLATALGGVGFI
Mb2180c|M.bovis_AF2122/97 SMGGVAILAGIWAGYLGAHLAGLAFDGEGIGASGLLVLGLATALGGVGFI
MMAR_3196|M.marinum_M SMGGVAILAGIWAGYFGTHLAGLAFDGEGITASGLLVLGLATSLGGVGFL
MUL_3504|M.ulcerans_Agy99 SMGGVAILAGIWAGYFGTHLAGLAFDGEGITASGLLVLGLATSLGGVGFL
MLBr_00911|M.leprae_Br4923 SMGGVAIVAGIWAGYLGTHLAGLAFDGEGVSASGVLVLGLATALGGVGFL
MAV_2333|M.avium_104 SMGGVAIIAGIWAGYLGTHLAGLAFDGEGISASGLLVLSLATVLGIVGFL
MAB_2003|M.abscessus_ATCC_1997 SMGGVAILAGMWAGYFGSHLVGIAFGSDGPSASGLLVLALATMLGGVGFI
*******:**:*..*:*:**.*: :.. * ***:***.*** ** ***:
Mflv_2985|M.gilvum_PYR-GCK DDLIKLRRARNLGLNKTAKTVGILVAAVLFGVLALQFRNADGLTPGSAEL
Mvan_3526|M.vanbaalenii_PYR-1 DDLIKIRRARNLGLNKTAKTVGILVAAVLFGVLALQFRNVDGLTPGSAEL
TH_1328|M.thermoresistible__bu DDLIKIRRARNLGLNKTAKTVGILLAAVAFGVLALQFRNADGLTPGAAEL
MSMEG_4230|M.smegmatis_MC2_155 DDMIKLKRARNLGLNKTAKTVGQLFAAVLFGVLALQFRNGDGLTPGSAEL
Rv2156c|M.tuberculosis_H37Rv DDLIKIRRSRNLGLNKTAKTVGQITSAVLFGVLVLQFRNAAGLTPGSADL
Mb2180c|M.bovis_AF2122/97 DDLIKIRRSRNLGLNKTAKTVGQITSAVLFGVLVLQFRNAAGLTPGSADL
MMAR_3196|M.marinum_M DDLIKLRRSRNLGLNKTAKTVGQITSAVLFAVLVLQFRNPAGLAPASAEL
MUL_3504|M.ulcerans_Agy99 DDMIKLRRSRNLGLNKTAKTVGQITSAVLFAVLVLQFRNPAGLAPASAEL
MLBr_00911|M.leprae_Br4923 DDLIKIRRSRNLGLNKTAKTVGQITAAVLFGVLVLQFRNGAGLTPASADL
MAV_2333|M.avium_104 DDLIKIRRSRNLGLNKTAKTIGQVAAAVLFGVLALGFRNANGLTPASADL
MAB_2003|M.abscessus_ATCC_1997 DDFIKIRKARNLGLNKTSKTVGQILSALVFGVLVLQFRNTDGLTPGSPQL
**:**::::********:**:* : :*: *.**.* *** **:*.:.:*
Mflv_2985|M.gilvum_PYR-GCK SYVREIATVTLAPAVFVLFCVVVVSAWSNAVNFTDGLDGLAAGAMAMVCA
Mvan_3526|M.vanbaalenii_PYR-1 SYVREIATVTLAPAVFVLFCVVVVSAWSNAVNFTDGLDGLAAGAMAMVCA
TH_1328|M.thermoresistible__bu SYVREIATVTMPYLVFVLFCVLVISAWSNAVNFTDGLDGLAAGAMAMVCA
MSMEG_4230|M.smegmatis_MC2_155 SYVREIATVTLAPALFVLFCVVVVSAWSNAVNFTDGLDGLAAGAMAMVTA
Rv2156c|M.tuberculosis_H37Rv SYVREIATVTLAPVLFVLFCVVIVSAWSNAVNFTDGLDGLAAGTMAMVTA
Mb2180c|M.bovis_AF2122/97 SYVREIATVTLAPVLFVLFCVVIVSAWSNAVNFTDGLDGLAAGTMAMVTA
MMAR_3196|M.marinum_M SYVREIATVTLTPALFVLFCVLVVSAWSNAVNFTDGLDGLAAGCMAMVTG
MUL_3504|M.ulcerans_Agy99 SYVREIATVTLTPALFVLFCVLVVSAWSNAVNFTDGLDGLAAGCMAMVTG
MLBr_00911|M.leprae_Br4923 SYVREIATVTLAPALFVLFCMVIVSAWSNAVNFTDGLDGLAAGSMAMVTA
MAV_2333|M.avium_104 SYVREIATVTLAPGLFVLFCVVVVSAWSNAVNFTDGLDGLAAGSMAMVTA
MAB_2003|M.abscessus_ATCC_1997 SYVREIATVAMPAAIFVLFCVILVMSWSNAVNFTDGLDGLAGGCMAMVTG
*********::. :*****:::: :***************.* **** .
Mflv_2985|M.gilvum_PYR-GCK AYVLITFWQFRNACATAPGVGCYNVRDPLDLAIIAAATAGACIGFLWWNA
Mvan_3526|M.vanbaalenii_PYR-1 AYVLITFWQFRNACATSPGVGCYNVRDPLDLAIIAAATAGACIGFLWWNA
TH_1328|M.thermoresistible__bu AYVLITFWQYRNACATSPDLGCYNVRDPLDLAIVAAATAGACIGFLWWNA
MSMEG_4230|M.smegmatis_MC2_155 AYVLITFWQYRNACATAPGLGCYNVRDPLDLALVAAATAGACVGFLWWNA
Rv2156c|M.tuberculosis_H37Rv AYVLITFWQYRNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
Mb2180c|M.bovis_AF2122/97 AYVLITFWQYRNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
MMAR_3196|M.marinum_M AYVLITFWQDHNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
MUL_3504|M.ulcerans_Agy99 AYVLITFWQDHNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
MLBr_00911|M.leprae_Br4923 AYVLITFWQYRNACVTAPGLGCYNVRDPLDLTLIAAATVGACIGFLWWNA
MAV_2333|M.avium_104 AYVLITFWQYRNACVTAPGLGCYNVRDPLDLAIVAAATAGACIGFLWWNA
MAB_2003|M.abscessus_ATCC_1997 AYVIVTFWQYRNACSTHPGIACYNVRDPLDLAVIAAATAGACIGFLWWNA
***::**** :*** * *.:.**********:::****.***:*******
Mflv_2985|M.gilvum_PYR-GCK APAKIFMGDTGSLALGGIIAGLSVTSRTEMLAVVLGALFVAEVTSVVVQI
Mvan_3526|M.vanbaalenii_PYR-1 APAKIFMGDTGSLALGGIIAGLSVTSRTEMLAVVLGALFVAEVTSVVVQI
TH_1328|M.thermoresistible__bu APAKIFMGDTGSLALGGIIAGLSVTSRTEILAIVLGALFVAEVTSVVVQI
MSMEG_4230|M.smegmatis_MC2_155 APAKIFMGDTGSLALGGIIAGISVTSRTEILAVVLGALFVAEVTSVVVQI
Rv2156c|M.tuberculosis_H37Rv APAKIFMGDTGSLALGGVIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
Mb2180c|M.bovis_AF2122/97 APAKIFMGDTGSLALGGVIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
MMAR_3196|M.marinum_M APAKIFMGDTGSLALGGIIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
MUL_3504|M.ulcerans_Agy99 APAKIFMGDTGSLALGGIIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
MLBr_00911|M.leprae_Br4923 APAKVFMGDTGSLALGGVIAGLSVTSRTEILAVVLGSLFVAEITSVVLQI
MAV_2333|M.avium_104 APAKIFMGDTGSLALGGIIAGISVTSRTEILAVVLGSLFVAEVSSVVLQI
MAB_2003|M.abscessus_ATCC_1997 APAKIFMGDTGSLALGGVIAGLSVTTRTELLAVVLGALFVAEIVSVVLQI
****:************:***:***:***:**:***:*****: ***:**
Mflv_2985|M.gilvum_PYR-GCK LAFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFY
Mvan_3526|M.vanbaalenii_PYR-1 LAFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFY
TH_1328|M.thermoresistible__bu LVFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFY
MSMEG_4230|M.smegmatis_MC2_155 LAFRTTGRRVFRMAPFHHHFELVGWAETQVIIRFWLLTAIACGLGVALFY
Rv2156c|M.tuberculosis_H37Rv LTFRTTGRRMFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
Mb2180c|M.bovis_AF2122/97 LTFRTTGRRMFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
MMAR_3196|M.marinum_M LTFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
MUL_3504|M.ulcerans_Agy99 LTFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
MLBr_00911|M.leprae_Br4923 LAFRTTGRRVFRMAPFHHHFELAGWAETTVIIRFWLLTAIACGLGVVLFY
MAV_2333|M.avium_104 LTFRTTGRRVFRMAPFHHHFELAGWAETTVIIRFWLLTAIACGLGVALFY
MAB_2003|M.abscessus_ATCC_1997 AAFRTTGRRVFRMAPFHHHFELLGWAETTVIIRFWLLTAIACGLGLALFY
.*******:************ ***** ***********:****:.***
Mflv_2985|M.gilvum_PYR-GCK SEWLTTVGA
Mvan_3526|M.vanbaalenii_PYR-1 SEWLTTVGA
TH_1328|M.thermoresistible__bu GEWLTTVGA
MSMEG_4230|M.smegmatis_MC2_155 GEWLTAVGA
Rv2156c|M.tuberculosis_H37Rv GEWLAAVGA
Mb2180c|M.bovis_AF2122/97 GEWLAAVGA
MMAR_3196|M.marinum_M GEWLAAIGA
MUL_3504|M.ulcerans_Agy99 GEWLAAIGA
MLBr_00911|M.leprae_Br4923 GEWLATIGA
MAV_2333|M.avium_104 GEWLAAIGA
MAB_2003|M.abscessus_ATCC_1997 GEWLATIGD
.***:::*