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M. smegmatis MC2 155 MSMEG_4230 (mraY)

annotation: phospho-N-acetylmuramoyl-pentapeptide-transferase
coordinates: 4311875 - 4312954
length: 359

MLILIAVGIALAVSILLTPALIRLFTKQGLGHEIREDGPPSHAKKRGTPSMGGVAILAGIWAGYLGSHLV
GMAMGGDGPSASGLLVLGLATVLGGVGFIDDMIKLKRARNLGLNKTAKTVGQLFAAVLFGVLALQFRNGD
GLTPGSAELSYVREIATVTLAPALFVLFCVVVVSAWSNAVNFTDGLDGLAAGAMAMVTAAYVLITFWQYR
NACATAPGLGCYNVRDPLDLALVAAATAGACVGFLWWNAAPAKIFMGDTGSLALGGIIAGISVTSRTEIL
AVVLGALFVAEVTSVVVQILAFRTTGRRVFRMAPFHHHFELVGWAETQVIIRFWLLTAIACGLGVALFYG
EWLTAVGA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4230mraY-100% (359)phospho-N-acetylmuramoyl-pentapeptide-transferase
M. smegmatis MC2 155MSMEG_4947-3e-1726.36% (330) glycosyl trasferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2180cmraY0.087.19% (359) phospho-N-acetylmuramoyl-pentapeptide-transferase
M. gilvum PYR-GCKMflv_2985mraY0.089.69% (359) phospho-N-acetylmuramoyl-pentapeptide-transferase
M. tuberculosis H37RvRv2156cmraY0.087.19% (359) phospho-N-acetylmuramoyl-pentapeptide-transferase
M. leprae Br4923MLBr_00911mraY0.085.24% (359) phospho-N-acetylmuramoyl-pentapeptide-transferase
M. abscessus ATCC 19977MAB_2003mraY1e-17379.61% (358) phospho-N-acetylmuramoyl-pentapeptide-transferase
M. marinum MMMAR_3196mraY1e-18086.35% (359) phospho-N-acetylmuramoyl- pentappeptidetransferase MurX
M. avium 104MAV_2333mraY0.086.91% (359) phospho-N-acetylmuramoyl-pentapeptide-transferase
M. thermoresistible (build 8)TH_1328-0.088.86% (359) Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX
M. ulcerans Agy99MUL_3504mraY1e-18086.63% (359) phospho-N-acetylmuramoyl-pentapeptide-transferase
M. vanbaalenii PYR-1Mvan_3526mraY0.089.14% (359) phospho-N-acetylmuramoyl-pentapeptide-transferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2985|M.gilvum_PYR-GCK          MRQILIAVAIALAVAILLTPVLIRLFTRQGFGHEIREDGPPSHHKKRGTP
Mvan_3526|M.vanbaalenii_PYR-1       MRQILIAVAIAVAVSILLTPVLIRLFTRQGFGHEIREDGPPSHHKKRGTP
TH_1328|M.thermoresistible__bu      MRQILIAAGIALAVSILLTPALIRLFTRQGFGHEIREDGPPSHHKKRGTP
MSMEG_4230|M.smegmatis_MC2_155      MMLILIAVGIALAVSILLTPALIRLFTKQGLGHEIREDGPPSHAKKRGTP
MLBr_00911|M.leprae_Br4923          MRQILVAVTVALVVSILLTPALIRLFTRHGFGQEIREDGPPSHHNKRGTP
MAV_2333|M.avium_104                MRQILIAVAIALTVSILLTPALIRLFTRQGFGHHTREDGPPTHHAKRGTP
Mb2180c|M.bovis_AF2122/97           MRQILIAVAVAVTVSILLTPVLIRLFTKQGFGHQIREDGPPSHHTKRGTP
Rv2156c|M.tuberculosis_H37Rv        MRQILIAVAVAVTVSILLTPVLIRLFTKQGFGHQIREDGPPSHHTKRGTP
MMAR_3196|M.marinum_M               MRQIMIAVAIAVAVSILLTPALIRLFTKQGFGHQIREDGPPSHHSKRGTP
MUL_3504|M.ulcerans_Agy99           MRQIMIAVAIAVAVSILLTPALIRLFTKQGFGHQIREDGPPSHHSKRGTP
MAB_2003|M.abscessus_ATCC_1997      MRQIIIAAGIAILVSIMLTPVLIRVFSRQGFGQEIRDDGPQHHQKKRGTP
                                    *  *::*. :*: *:*:***.***:*:::*:*:. *:***  *  *****

Mflv_2985|M.gilvum_PYR-GCK          SMGGVAIIAGIWVSYFGTHLVGVLMDGKGPSASGLLVLGLATSLGVVGFL
Mvan_3526|M.vanbaalenii_PYR-1       SMGGVAIVAGIWASYFGTHLVGVVIDGKGPSASGLLVLGLATALGAVGFL
TH_1328|M.thermoresistible__bu      SMGGVAILAGMWASYLGTHLVGIALDGRGPSASGLLVLGLATALGLVGFI
MSMEG_4230|M.smegmatis_MC2_155      SMGGVAILAGIWAGYLGSHLVGMAMGGDGPSASGLLVLGLATVLGGVGFI
MLBr_00911|M.leprae_Br4923          SMGGVAIVAGIWAGYLGTHLAGLAFDGEGVSASGVLVLGLATALGGVGFL
MAV_2333|M.avium_104                SMGGVAIIAGIWAGYLGTHLAGLAFDGEGISASGLLVLSLATVLGIVGFL
Mb2180c|M.bovis_AF2122/97           SMGGVAILAGIWAGYLGAHLAGLAFDGEGIGASGLLVLGLATALGGVGFI
Rv2156c|M.tuberculosis_H37Rv        SMGGVAILAGIWAGYLGAHLAGLAFDGEGIGASGLLVLGLATALGGVGFI
MMAR_3196|M.marinum_M               SMGGVAILAGIWAGYFGTHLAGLAFDGEGITASGLLVLGLATSLGGVGFL
MUL_3504|M.ulcerans_Agy99           SMGGVAILAGIWAGYFGTHLAGLAFDGEGITASGLLVLGLATSLGGVGFL
MAB_2003|M.abscessus_ATCC_1997      SMGGVAILAGMWAGYFGSHLVGIAFGSDGPSASGLLVLALATMLGGVGFI
                                    *******:**:*..*:*:**.*: :.. *  ***:***.*** ** ***:

Mflv_2985|M.gilvum_PYR-GCK          DDLIKLRRARNLGLNKTAKTVGILVAAVLFGVLALQFRNADGLTPGSAEL
Mvan_3526|M.vanbaalenii_PYR-1       DDLIKIRRARNLGLNKTAKTVGILVAAVLFGVLALQFRNVDGLTPGSAEL
TH_1328|M.thermoresistible__bu      DDLIKIRRARNLGLNKTAKTVGILLAAVAFGVLALQFRNADGLTPGAAEL
MSMEG_4230|M.smegmatis_MC2_155      DDMIKLKRARNLGLNKTAKTVGQLFAAVLFGVLALQFRNGDGLTPGSAEL
MLBr_00911|M.leprae_Br4923          DDLIKIRRSRNLGLNKTAKTVGQITAAVLFGVLVLQFRNGAGLTPASADL
MAV_2333|M.avium_104                DDLIKIRRSRNLGLNKTAKTIGQVAAAVLFGVLALGFRNANGLTPASADL
Mb2180c|M.bovis_AF2122/97           DDLIKIRRSRNLGLNKTAKTVGQITSAVLFGVLVLQFRNAAGLTPGSADL
Rv2156c|M.tuberculosis_H37Rv        DDLIKIRRSRNLGLNKTAKTVGQITSAVLFGVLVLQFRNAAGLTPGSADL
MMAR_3196|M.marinum_M               DDLIKLRRSRNLGLNKTAKTVGQITSAVLFAVLVLQFRNPAGLAPASAEL
MUL_3504|M.ulcerans_Agy99           DDMIKLRRSRNLGLNKTAKTVGQITSAVLFAVLVLQFRNPAGLAPASAEL
MAB_2003|M.abscessus_ATCC_1997      DDFIKIRKARNLGLNKTSKTVGQILSALVFGVLVLQFRNTDGLTPGSPQL
                                    **:**::::********:**:* : :*: *.**.* ***  **:*.:.:*

Mflv_2985|M.gilvum_PYR-GCK          SYVREIATVTLAPAVFVLFCVVVVSAWSNAVNFTDGLDGLAAGAMAMVCA
Mvan_3526|M.vanbaalenii_PYR-1       SYVREIATVTLAPAVFVLFCVVVVSAWSNAVNFTDGLDGLAAGAMAMVCA
TH_1328|M.thermoresistible__bu      SYVREIATVTMPYLVFVLFCVLVISAWSNAVNFTDGLDGLAAGAMAMVCA
MSMEG_4230|M.smegmatis_MC2_155      SYVREIATVTLAPALFVLFCVVVVSAWSNAVNFTDGLDGLAAGAMAMVTA
MLBr_00911|M.leprae_Br4923          SYVREIATVTLAPALFVLFCMVIVSAWSNAVNFTDGLDGLAAGSMAMVTA
MAV_2333|M.avium_104                SYVREIATVTLAPGLFVLFCVVVVSAWSNAVNFTDGLDGLAAGSMAMVTA
Mb2180c|M.bovis_AF2122/97           SYVREIATVTLAPVLFVLFCVVIVSAWSNAVNFTDGLDGLAAGTMAMVTA
Rv2156c|M.tuberculosis_H37Rv        SYVREIATVTLAPVLFVLFCVVIVSAWSNAVNFTDGLDGLAAGTMAMVTA
MMAR_3196|M.marinum_M               SYVREIATVTLTPALFVLFCVLVVSAWSNAVNFTDGLDGLAAGCMAMVTG
MUL_3504|M.ulcerans_Agy99           SYVREIATVTLTPALFVLFCVLVVSAWSNAVNFTDGLDGLAAGCMAMVTG
MAB_2003|M.abscessus_ATCC_1997      SYVREIATVAMPAAIFVLFCVILVMSWSNAVNFTDGLDGLAGGCMAMVTG
                                    *********::.  :*****:::: :***************.* **** .

Mflv_2985|M.gilvum_PYR-GCK          AYVLITFWQFRNACATAPGVGCYNVRDPLDLAIIAAATAGACIGFLWWNA
Mvan_3526|M.vanbaalenii_PYR-1       AYVLITFWQFRNACATSPGVGCYNVRDPLDLAIIAAATAGACIGFLWWNA
TH_1328|M.thermoresistible__bu      AYVLITFWQYRNACATSPDLGCYNVRDPLDLAIVAAATAGACIGFLWWNA
MSMEG_4230|M.smegmatis_MC2_155      AYVLITFWQYRNACATAPGLGCYNVRDPLDLALVAAATAGACVGFLWWNA
MLBr_00911|M.leprae_Br4923          AYVLITFWQYRNACVTAPGLGCYNVRDPLDLTLIAAATVGACIGFLWWNA
MAV_2333|M.avium_104                AYVLITFWQYRNACVTAPGLGCYNVRDPLDLAIVAAATAGACIGFLWWNA
Mb2180c|M.bovis_AF2122/97           AYVLITFWQYRNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
Rv2156c|M.tuberculosis_H37Rv        AYVLITFWQYRNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
MMAR_3196|M.marinum_M               AYVLITFWQDHNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
MUL_3504|M.ulcerans_Agy99           AYVLITFWQDHNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
MAB_2003|M.abscessus_ATCC_1997      AYVIVTFWQYRNACSTHPGIACYNVRDPLDLAVIAAATAGACIGFLWWNA
                                    ***::**** :*** * *.:.**********:::****.***:*******

Mflv_2985|M.gilvum_PYR-GCK          APAKIFMGDTGSLALGGIIAGLSVTSRTEMLAVVLGALFVAEVTSVVVQI
Mvan_3526|M.vanbaalenii_PYR-1       APAKIFMGDTGSLALGGIIAGLSVTSRTEMLAVVLGALFVAEVTSVVVQI
TH_1328|M.thermoresistible__bu      APAKIFMGDTGSLALGGIIAGLSVTSRTEILAIVLGALFVAEVTSVVVQI
MSMEG_4230|M.smegmatis_MC2_155      APAKIFMGDTGSLALGGIIAGISVTSRTEILAVVLGALFVAEVTSVVVQI
MLBr_00911|M.leprae_Br4923          APAKVFMGDTGSLALGGVIAGLSVTSRTEILAVVLGSLFVAEITSVVLQI
MAV_2333|M.avium_104                APAKIFMGDTGSLALGGIIAGISVTSRTEILAVVLGSLFVAEVSSVVLQI
Mb2180c|M.bovis_AF2122/97           APAKIFMGDTGSLALGGVIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
Rv2156c|M.tuberculosis_H37Rv        APAKIFMGDTGSLALGGVIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
MMAR_3196|M.marinum_M               APAKIFMGDTGSLALGGIIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
MUL_3504|M.ulcerans_Agy99           APAKIFMGDTGSLALGGIIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
MAB_2003|M.abscessus_ATCC_1997      APAKIFMGDTGSLALGGVIAGLSVTTRTELLAVVLGALFVAEIVSVVLQI
                                    ****:************:***:***:***:**:***:*****: ***:**

Mflv_2985|M.gilvum_PYR-GCK          LAFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFY
Mvan_3526|M.vanbaalenii_PYR-1       LAFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFY
TH_1328|M.thermoresistible__bu      LVFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFY
MSMEG_4230|M.smegmatis_MC2_155      LAFRTTGRRVFRMAPFHHHFELVGWAETQVIIRFWLLTAIACGLGVALFY
MLBr_00911|M.leprae_Br4923          LAFRTTGRRVFRMAPFHHHFELAGWAETTVIIRFWLLTAIACGLGVVLFY
MAV_2333|M.avium_104                LTFRTTGRRVFRMAPFHHHFELAGWAETTVIIRFWLLTAIACGLGVALFY
Mb2180c|M.bovis_AF2122/97           LTFRTTGRRMFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
Rv2156c|M.tuberculosis_H37Rv        LTFRTTGRRMFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
MMAR_3196|M.marinum_M               LTFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
MUL_3504|M.ulcerans_Agy99           LTFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
MAB_2003|M.abscessus_ATCC_1997      AAFRTTGRRVFRMAPFHHHFELLGWAETTVIIRFWLLTAIACGLGLALFY
                                     .*******:************ ***** ***********:****:.***

Mflv_2985|M.gilvum_PYR-GCK          SEWLTTVGA
Mvan_3526|M.vanbaalenii_PYR-1       SEWLTTVGA
TH_1328|M.thermoresistible__bu      GEWLTTVGA
MSMEG_4230|M.smegmatis_MC2_155      GEWLTAVGA
MLBr_00911|M.leprae_Br4923          GEWLATIGA
MAV_2333|M.avium_104                GEWLAAIGA
Mb2180c|M.bovis_AF2122/97           GEWLAAVGA
Rv2156c|M.tuberculosis_H37Rv        GEWLAAVGA
MMAR_3196|M.marinum_M               GEWLAAIGA
MUL_3504|M.ulcerans_Agy99           GEWLAAIGA
MAB_2003|M.abscessus_ATCC_1997      GEWLATIGD
                                    .***:::*