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M. abscessus ATCC 19977 MAB_2003 (mraY)

annotation: phospho-N-acetylmuramoyl-pentapeptide-transferase
coordinates: 2001747 - 2002826
length: 359

MRQIIIAAGIAILVSIMLTPVLIRVFSRQGFGQEIRDDGPQHHQKKRGTPSMGGVAILAGMWAGYFGSHL
VGIAFGSDGPSASGLLVLALATMLGGVGFIDDFIKIRKARNLGLNKTSKTVGQILSALVFGVLVLQFRNT
DGLTPGSPQLSYVREIATVAMPAAIFVLFCVILVMSWSNAVNFTDGLDGLAGGCMAMVTGAYVIVTFWQY
RNACSTHPGIACYNVRDPLDLAVIAAATAGACIGFLWWNAAPAKIFMGDTGSLALGGVIAGLSVTTRTEL
LAVVLGALFVAEIVSVVLQIAAFRTTGRRVFRMAPFHHHFELLGWAETTVIIRFWLLTAIACGLGLALFY
GEWLATIGD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2003mraY-100% (359)phospho-N-acetylmuramoyl-pentapeptide-transferase
M. abscessus ATCC 19977MAB_1445-1e-1829.32% (324) putative undecaprenyl-phosphate

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2180cmraY1e-17180.17% (358) phospho-N-acetylmuramoyl-pentapeptide-transferase
M. gilvum PYR-GCKMflv_2985mraY1e-17078.77% (358) phospho-N-acetylmuramoyl-pentapeptide-transferase
M. tuberculosis H37RvRv2156cmraY1e-17180.17% (358) phospho-N-acetylmuramoyl-pentapeptide-transferase
M. leprae Br4923MLBr_00911mraY1e-17079.05% (358) phospho-N-acetylmuramoyl-pentapeptide-transferase
M. marinum MMMAR_3196mraY1e-17079.61% (358) phospho-N-acetylmuramoyl- pentappeptidetransferase MurX
M. avium 104MAV_2333mraY1e-16677.37% (358) phospho-N-acetylmuramoyl-pentapeptide-transferase
M. smegmatis MC2 155MSMEG_4230mraY1e-17379.61% (358) phospho-N-acetylmuramoyl-pentapeptide-transferase
M. thermoresistible (build 8)TH_1328-1e-17380.45% (358) Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX
M. ulcerans Agy99MUL_3504mraY1e-17079.61% (358) phospho-N-acetylmuramoyl-pentapeptide-transferase
M. vanbaalenii PYR-1Mvan_3526mraY1e-17279.61% (358) phospho-N-acetylmuramoyl-pentapeptide-transferase

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_00911|M.leprae_Br4923          MRQILVAVTVALVVSILLTPALIRLFTRHGFGQEIREDGPPSHHNKRGTP
MAV_2333|M.avium_104                MRQILIAVAIALTVSILLTPALIRLFTRQGFGHHTREDGPPTHHAKRGTP
Mb2180c|M.bovis_AF2122/97           MRQILIAVAVAVTVSILLTPVLIRLFTKQGFGHQIREDGPPSHHTKRGTP
Rv2156c|M.tuberculosis_H37Rv        MRQILIAVAVAVTVSILLTPVLIRLFTKQGFGHQIREDGPPSHHTKRGTP
MMAR_3196|M.marinum_M               MRQIMIAVAIAVAVSILLTPALIRLFTKQGFGHQIREDGPPSHHSKRGTP
MUL_3504|M.ulcerans_Agy99           MRQIMIAVAIAVAVSILLTPALIRLFTKQGFGHQIREDGPPSHHSKRGTP
Mflv_2985|M.gilvum_PYR-GCK          MRQILIAVAIALAVAILLTPVLIRLFTRQGFGHEIREDGPPSHHKKRGTP
Mvan_3526|M.vanbaalenii_PYR-1       MRQILIAVAIAVAVSILLTPVLIRLFTRQGFGHEIREDGPPSHHKKRGTP
TH_1328|M.thermoresistible__bu      MRQILIAAGIALAVSILLTPALIRLFTRQGFGHEIREDGPPSHHKKRGTP
MSMEG_4230|M.smegmatis_MC2_155      MMLILIAVGIALAVSILLTPALIRLFTKQGLGHEIREDGPPSHAKKRGTP
MAB_2003|M.abscessus_ATCC_1997      MRQIIIAAGIAILVSIMLTPVLIRVFSRQGFGQEIRDDGPQHHQKKRGTP
                                    *  *::*. :*: *:*:***.***:*:::*:*:. *:***  *  *****

MLBr_00911|M.leprae_Br4923          SMGGVAIVAGIWAGYLGTHLAGLAFDGEGVSASGVLVLGLATALGGVGFL
MAV_2333|M.avium_104                SMGGVAIIAGIWAGYLGTHLAGLAFDGEGISASGLLVLSLATVLGIVGFL
Mb2180c|M.bovis_AF2122/97           SMGGVAILAGIWAGYLGAHLAGLAFDGEGIGASGLLVLGLATALGGVGFI
Rv2156c|M.tuberculosis_H37Rv        SMGGVAILAGIWAGYLGAHLAGLAFDGEGIGASGLLVLGLATALGGVGFI
MMAR_3196|M.marinum_M               SMGGVAILAGIWAGYFGTHLAGLAFDGEGITASGLLVLGLATSLGGVGFL
MUL_3504|M.ulcerans_Agy99           SMGGVAILAGIWAGYFGTHLAGLAFDGEGITASGLLVLGLATSLGGVGFL
Mflv_2985|M.gilvum_PYR-GCK          SMGGVAIIAGIWVSYFGTHLVGVLMDGKGPSASGLLVLGLATSLGVVGFL
Mvan_3526|M.vanbaalenii_PYR-1       SMGGVAIVAGIWASYFGTHLVGVVIDGKGPSASGLLVLGLATALGAVGFL
TH_1328|M.thermoresistible__bu      SMGGVAILAGMWASYLGTHLVGIALDGRGPSASGLLVLGLATALGLVGFI
MSMEG_4230|M.smegmatis_MC2_155      SMGGVAILAGIWAGYLGSHLVGMAMGGDGPSASGLLVLGLATVLGGVGFI
MAB_2003|M.abscessus_ATCC_1997      SMGGVAILAGMWAGYFGSHLVGIAFGSDGPSASGLLVLALATMLGGVGFI
                                    *******:**:*..*:*:**.*: :.. *  ***:***.*** ** ***:

MLBr_00911|M.leprae_Br4923          DDLIKIRRSRNLGLNKTAKTVGQITAAVLFGVLVLQFRNGAGLTPASADL
MAV_2333|M.avium_104                DDLIKIRRSRNLGLNKTAKTIGQVAAAVLFGVLALGFRNANGLTPASADL
Mb2180c|M.bovis_AF2122/97           DDLIKIRRSRNLGLNKTAKTVGQITSAVLFGVLVLQFRNAAGLTPGSADL
Rv2156c|M.tuberculosis_H37Rv        DDLIKIRRSRNLGLNKTAKTVGQITSAVLFGVLVLQFRNAAGLTPGSADL
MMAR_3196|M.marinum_M               DDLIKLRRSRNLGLNKTAKTVGQITSAVLFAVLVLQFRNPAGLAPASAEL
MUL_3504|M.ulcerans_Agy99           DDMIKLRRSRNLGLNKTAKTVGQITSAVLFAVLVLQFRNPAGLAPASAEL
Mflv_2985|M.gilvum_PYR-GCK          DDLIKLRRARNLGLNKTAKTVGILVAAVLFGVLALQFRNADGLTPGSAEL
Mvan_3526|M.vanbaalenii_PYR-1       DDLIKIRRARNLGLNKTAKTVGILVAAVLFGVLALQFRNVDGLTPGSAEL
TH_1328|M.thermoresistible__bu      DDLIKIRRARNLGLNKTAKTVGILLAAVAFGVLALQFRNADGLTPGAAEL
MSMEG_4230|M.smegmatis_MC2_155      DDMIKLKRARNLGLNKTAKTVGQLFAAVLFGVLALQFRNGDGLTPGSAEL
MAB_2003|M.abscessus_ATCC_1997      DDFIKIRKARNLGLNKTSKTVGQILSALVFGVLVLQFRNTDGLTPGSPQL
                                    **:**::::********:**:* : :*: *.**.* ***  **:*.:.:*

MLBr_00911|M.leprae_Br4923          SYVREIATVTLAPALFVLFCMVIVSAWSNAVNFTDGLDGLAAGSMAMVTA
MAV_2333|M.avium_104                SYVREIATVTLAPGLFVLFCVVVVSAWSNAVNFTDGLDGLAAGSMAMVTA
Mb2180c|M.bovis_AF2122/97           SYVREIATVTLAPVLFVLFCVVIVSAWSNAVNFTDGLDGLAAGTMAMVTA
Rv2156c|M.tuberculosis_H37Rv        SYVREIATVTLAPVLFVLFCVVIVSAWSNAVNFTDGLDGLAAGTMAMVTA
MMAR_3196|M.marinum_M               SYVREIATVTLTPALFVLFCVLVVSAWSNAVNFTDGLDGLAAGCMAMVTG
MUL_3504|M.ulcerans_Agy99           SYVREIATVTLTPALFVLFCVLVVSAWSNAVNFTDGLDGLAAGCMAMVTG
Mflv_2985|M.gilvum_PYR-GCK          SYVREIATVTLAPAVFVLFCVVVVSAWSNAVNFTDGLDGLAAGAMAMVCA
Mvan_3526|M.vanbaalenii_PYR-1       SYVREIATVTLAPAVFVLFCVVVVSAWSNAVNFTDGLDGLAAGAMAMVCA
TH_1328|M.thermoresistible__bu      SYVREIATVTMPYLVFVLFCVLVISAWSNAVNFTDGLDGLAAGAMAMVCA
MSMEG_4230|M.smegmatis_MC2_155      SYVREIATVTLAPALFVLFCVVVVSAWSNAVNFTDGLDGLAAGAMAMVTA
MAB_2003|M.abscessus_ATCC_1997      SYVREIATVAMPAAIFVLFCVILVMSWSNAVNFTDGLDGLAGGCMAMVTG
                                    *********::.  :*****:::: :***************.* **** .

MLBr_00911|M.leprae_Br4923          AYVLITFWQYRNACVTAPGLGCYNVRDPLDLTLIAAATVGACIGFLWWNA
MAV_2333|M.avium_104                AYVLITFWQYRNACVTAPGLGCYNVRDPLDLAIVAAATAGACIGFLWWNA
Mb2180c|M.bovis_AF2122/97           AYVLITFWQYRNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
Rv2156c|M.tuberculosis_H37Rv        AYVLITFWQYRNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
MMAR_3196|M.marinum_M               AYVLITFWQDHNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
MUL_3504|M.ulcerans_Agy99           AYVLITFWQDHNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
Mflv_2985|M.gilvum_PYR-GCK          AYVLITFWQFRNACATAPGVGCYNVRDPLDLAIIAAATAGACIGFLWWNA
Mvan_3526|M.vanbaalenii_PYR-1       AYVLITFWQFRNACATSPGVGCYNVRDPLDLAIIAAATAGACIGFLWWNA
TH_1328|M.thermoresistible__bu      AYVLITFWQYRNACATSPDLGCYNVRDPLDLAIVAAATAGACIGFLWWNA
MSMEG_4230|M.smegmatis_MC2_155      AYVLITFWQYRNACATAPGLGCYNVRDPLDLALVAAATAGACVGFLWWNA
MAB_2003|M.abscessus_ATCC_1997      AYVIVTFWQYRNACSTHPGIACYNVRDPLDLAVIAAATAGACIGFLWWNA
                                    ***::**** :*** * *.:.**********:::****.***:*******

MLBr_00911|M.leprae_Br4923          APAKVFMGDTGSLALGGVIAGLSVTSRTEILAVVLGSLFVAEITSVVLQI
MAV_2333|M.avium_104                APAKIFMGDTGSLALGGIIAGISVTSRTEILAVVLGSLFVAEVSSVVLQI
Mb2180c|M.bovis_AF2122/97           APAKIFMGDTGSLALGGVIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
Rv2156c|M.tuberculosis_H37Rv        APAKIFMGDTGSLALGGVIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
MMAR_3196|M.marinum_M               APAKIFMGDTGSLALGGIIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
MUL_3504|M.ulcerans_Agy99           APAKIFMGDTGSLALGGIIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
Mflv_2985|M.gilvum_PYR-GCK          APAKIFMGDTGSLALGGIIAGLSVTSRTEMLAVVLGALFVAEVTSVVVQI
Mvan_3526|M.vanbaalenii_PYR-1       APAKIFMGDTGSLALGGIIAGLSVTSRTEMLAVVLGALFVAEVTSVVVQI
TH_1328|M.thermoresistible__bu      APAKIFMGDTGSLALGGIIAGLSVTSRTEILAIVLGALFVAEVTSVVVQI
MSMEG_4230|M.smegmatis_MC2_155      APAKIFMGDTGSLALGGIIAGISVTSRTEILAVVLGALFVAEVTSVVVQI
MAB_2003|M.abscessus_ATCC_1997      APAKIFMGDTGSLALGGVIAGLSVTTRTELLAVVLGALFVAEIVSVVLQI
                                    ****:************:***:***:***:**:***:*****: ***:**

MLBr_00911|M.leprae_Br4923          LAFRTTGRRVFRMAPFHHHFELAGWAETTVIIRFWLLTAIACGLGVVLFY
MAV_2333|M.avium_104                LTFRTTGRRVFRMAPFHHHFELAGWAETTVIIRFWLLTAIACGLGVALFY
Mb2180c|M.bovis_AF2122/97           LTFRTTGRRMFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
Rv2156c|M.tuberculosis_H37Rv        LTFRTTGRRMFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
MMAR_3196|M.marinum_M               LTFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
MUL_3504|M.ulcerans_Agy99           LTFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
Mflv_2985|M.gilvum_PYR-GCK          LAFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFY
Mvan_3526|M.vanbaalenii_PYR-1       LAFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFY
TH_1328|M.thermoresistible__bu      LVFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFY
MSMEG_4230|M.smegmatis_MC2_155      LAFRTTGRRVFRMAPFHHHFELVGWAETQVIIRFWLLTAIACGLGVALFY
MAB_2003|M.abscessus_ATCC_1997      AAFRTTGRRVFRMAPFHHHFELLGWAETTVIIRFWLLTAIACGLGLALFY
                                     .*******:************ ***** ***********:****:.***

MLBr_00911|M.leprae_Br4923          GEWLATIGA
MAV_2333|M.avium_104                GEWLAAIGA
Mb2180c|M.bovis_AF2122/97           GEWLAAVGA
Rv2156c|M.tuberculosis_H37Rv        GEWLAAVGA
MMAR_3196|M.marinum_M               GEWLAAIGA
MUL_3504|M.ulcerans_Agy99           GEWLAAIGA
Mflv_2985|M.gilvum_PYR-GCK          SEWLTTVGA
Mvan_3526|M.vanbaalenii_PYR-1       SEWLTTVGA
TH_1328|M.thermoresistible__bu      GEWLTTVGA
MSMEG_4230|M.smegmatis_MC2_155      GEWLTAVGA
MAB_2003|M.abscessus_ATCC_1997      GEWLATIGD
                                    .***:::*