For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv1302 (rfe)

annotation: PROBABLE UNDECAPAPRENYL-PHOSPHATE ALPHA-N-ACETYLGLUCOSAMINYLTRANSFERASE RFE (UDP-GlcNAc TRANSFERASE)
coordinates: 1458295 - 1459509
length: 404

VQYGLEVSSDVAGVAGGLLALSYRGAGVPLRELALVGLTAAIITYFATGPVRMLASRLGAVAYPRERDVH
VTPTPRMGGLAMFLGIVGAVFLASQLPALTRGFVYSTGMPAVLVAGAVIMGIGLIDDRWGLDALTKFAGQ
ITAASVLVTMGVAWSVLYIPVGGVGTIVLDQASSILLTLALTVSIVNAMNFVDGLDGLAAGLGLITALAI
CMFSVGLLRDHGGDVLYYPPAVISVVLAGACLGFLPHNFHRAKIFMGDSGSMLIGLMLAAASTTAAGPIS
QNAYGARDVFALLSPFLLVVAVMFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRVVLII
YLWVGIVAFGAASSIFFNPRDTAAVMLGAIVVAGVATLIPLLRRGDDYYDPDLD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1302rfe-100% (404)PROBABLE UNDECAPAPRENYL-PHOSPHATE ALPHA-N-ACETYLGLUCOSAMINYLTRANSFERASE RFE (UDP-GlcNAc TRANSFERASE)
M. tuberculosis H37RvRv2156cmraY3e-2029.36% (327) phospho-N-acetylmuramoyl-pentapeptide-transferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1334rfe0.099.75% (404) putative undecapaprenyl-phosphate
M. gilvum PYR-GCKMflv_2310-0.083.20% (387) glycosyl transferase family protein
M. leprae Br4923MLBr_01137-0.089.45% (398) putative glycosyltransferase
M. abscessus ATCC 19977MAB_1445-0.082.64% (386) putative undecaprenyl-phosphate
M. marinum MMMAR_4095rfe0.094.13% (392) undecapaprenyl-phosphate alpha-N-
M. avium 104MAV_1519-0.093.97% (398) glycosyl transferase, group 4 family protein
M. smegmatis MC2 155MSMEG_4947-0.088.95% (380) glycosyl trasferase
M. thermoresistible (build 8)TH_1564rfe0.084.65% (404) PROBABLE UNDECAPAPRENYL-PHOSPHATE
M. ulcerans Agy99MUL_3962rfe0.094.13% (392) undecapaprenyl-phosphate alpha-N-
M. vanbaalenii PYR-1Mvan_4336-0.086.01% (386) glycosyl transferase family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2310|M.gilvum_PYR-GCK          -MDLASATITATRAG----ESLLALDERGAGVPLRELALVGLTAAIITYL
Mvan_4336|M.vanbaalenii_PYR-1       -MHLASATMTIAQAG----ESVMALSDRGAGVPLRELALVGLTAAIITYL
MSMEG_4947|M.smegmatis_MC2_155      MLQYGAPVITATRETGMDSQVVLALSDTGAGVPLRELALVGLTAAIITYF
TH_1564|M.thermoresistible__bu      -VQYGSAVVTAT-------DSILALSERGAGVPLRELALVGLTATIITYF
Rv1302|M.tuberculosis_H37Rv         -MQYGL-EVSSDVAG--VAGGLLALSYRGAGVPLRELALVGLTAAIITYF
Mb1334|M.bovis_AF2122/97            -MQYGL-EVSSDVAG--VAGGLLALSYRGAGVPLRELALVGLTAAIITYF
MAV_1519|M.avium_104                -MSSTVSLVSSDVTD--LAGGLLALSDRGAGVPLRELALVGLTAAIITYF
MMAR_4095|M.marinum_M               ------------MSS--VADGLLALSVRSAGVPLRELALVGLTAAIITYF
MUL_3962|M.ulcerans_Agy99           -----------MVSS--VADGLLALSVRSAGVPLRELALVGLTAAIITYF
MLBr_01137|M.leprae_Br4923          -MVQYVREMSSDLAT--FASGLLALFERSAGVPLRELALVGLTAAIITYF
MAB_1445|M.abscessus_ATCC_1997      ------------------MSELLALADRGAGVPLRELALVGLTAAITTFF
                                                         ::**   .***************:* *::

Mflv_2310|M.gilvum_PYR-GCK          ATGWVRVLATRWGAVAYPRERDVHLQPIARMGGLAMYIGVVAAVLLASQL
Mvan_4336|M.vanbaalenii_PYR-1       ATGWVRVLATRWGAVAYPRERDVHVAPTPRMGGLAMYLGVVAAVLLASQL
MSMEG_4947|M.smegmatis_MC2_155      ATGWVRVLAIRFGAVAYPRERDVHVQPTPRMGGLAMYIGVASAVLLASQL
TH_1564|M.thermoresistible__bu      ATGWVRVLAIRLGAVAYPRERDVHVRPTPRMGGLAMYIGVAAAVLLASQL
Rv1302|M.tuberculosis_H37Rv         ATGPVRMLASRLGAVAYPRERDVHVTPTPRMGGLAMFLGIVGAVFLASQL
Mb1334|M.bovis_AF2122/97            ATGPVRMLASRLGAVAYPRERDVHVTPTPRMGGLAMFLGIVGAVFLASQL
MAV_1519|M.avium_104                ATGPVRVLATRLGAVAYPRERDVHVTPTPRMGGLAMFLGVVCAVFLASQL
MMAR_4095|M.marinum_M               ATGPVRVLATRLGAVAYPRERDVHVTPTPRMGGLAMFLGVLAAVFLASQL
MUL_3962|M.ulcerans_Agy99           ATGPVRVLATRLGAVAYPRERDVHVTPTPRMGGLAMFLGVLAAVFLASQL
MLBr_01137|M.leprae_Br4923          ATGLVGVLANRLEAVAYPRERDVHVTPTPRMGGLAMYLGVLAAVFLASQL
MAB_1445|M.abscessus_ATCC_1997      CTGGVRMFATRVGAVAYPRERDVHLQPTPRMGGLGMYFGVCAAIFLASQL
                                    .** * ::* *  ***********: * .*****.*::*:  *::*****

Mflv_2310|M.gilvum_PYR-GCK          PALTRGFVYSSGLPAVVVAGGLIMVVGLIDDRWGLDALTKFAGQITAASV
Mvan_4336|M.vanbaalenii_PYR-1       PALTRGFVYSSGMPAVVVAGGLIMVVGLIDDRWGLDALTKFAGQITAASV
MSMEG_4947|M.smegmatis_MC2_155      PALTRGFVYSTGMPAVVVAGGLIMAIGLIDDRWGLDALTKFAGQITAASV
TH_1564|M.thermoresistible__bu      PALTRGFVYSSGMPAVVVAGGLIMAIGLIDDRWGLDALTKFAGQITAASV
Rv1302|M.tuberculosis_H37Rv         PALTRGFVYSTGMPAVLVAGAVIMGIGLIDDRWGLDALTKFAGQITAASV
Mb1334|M.bovis_AF2122/97            PALTRGFVYSTGMPAVLVAGAVIMGIGLIDDRWGLDALTKFAGQITAASV
MAV_1519|M.avium_104                PALTRGFVYSSGMPAVLVAGAVIMGIGLIDDRWGLDALTKFAGQITAASV
MMAR_4095|M.marinum_M               PALTRGFVYSTGMPAVLVAGAVIMGIGLIDDRWGLDALTKFAGQITAASV
MUL_3962|M.ulcerans_Agy99           PALTRGFVYSTGMPAVLVAGAVIMGIGLIDDRWGLDALTKFAGQITAASV
MLBr_01137|M.leprae_Br4923          PALTRGFVYSSGMPAVLVAGAVITGIGLIDDRWGLDALTKFAGQITAASV
MAB_1445|M.abscessus_ATCC_1997      PALTRGFVYSSGMPAVVVAGGIIMIVGLIDDKWGLDALTKFAGQVTAASV
                                    **********:*:***:***.:*  :*****:************:*****

Mflv_2310|M.gilvum_PYR-GCK          LVTMGVAWSVLYIPIGGVGTIVLDQVASILLTLAFTVALVNSMNFVDGLD
Mvan_4336|M.vanbaalenii_PYR-1       LVTMGVAWSVLYIPIGGVGTIVLDQVASILLTLALTVAIVNAMNFVDGLD
MSMEG_4947|M.smegmatis_MC2_155      LVTMGVAWSVLYIPIGGVGTIVLDQVSSILLTLALTVSIINAMNFVDGLD
TH_1564|M.thermoresistible__bu      LVTMGVAWSVLYIPIGGVGTIVLDQVSSILLTLALTVAVVNAMNFVDGLD
Rv1302|M.tuberculosis_H37Rv         LVTMGVAWSVLYIPVGGVGTIVLDQASSILLTLALTVSIVNAMNFVDGLD
Mb1334|M.bovis_AF2122/97            LVTMGVAWSVLYIPVGGVGTIVLDQASSILLTLALTVSIVNAMNFVDGLD
MAV_1519|M.avium_104                LVTMGVAWSVLYIPIGGVGTIVLDQASSILLTLALTVSVVNAMNFVDGLD
MMAR_4095|M.marinum_M               LVTMGVAWSVLYIPLGGVGTIVLDQASSILLTLALTVSIVNAMNFVDGLD
MUL_3962|M.ulcerans_Agy99           LVTMGVAWSVLYIPLGGVGTIVLDQASSILLTLALTVSIVNAMNFVDGLD
MLBr_01137|M.leprae_Br4923          LVTMGVAWSVLYIPLGGVGTIVLDQTSSILLTLALTVSIVNAINFVDGLD
MAB_1445|M.abscessus_ATCC_1997      LVTMGVAWSMIYIPFGGVGTIVLDQMSSILVTLALTVSIVNAMNFVDGLD
                                    *********::***.********** :***:***:**:::*::*******

Mflv_2310|M.gilvum_PYR-GCK          GLAAGLGLITASAICLFSVGLLHDHGGDVLFYPPAVISVVLAGACLGFLP
Mvan_4336|M.vanbaalenii_PYR-1       GLAAGLGLITASAICIFSVGLLRDHGGDVLFYPPAVISVVLAGVCLGFLP
MSMEG_4947|M.smegmatis_MC2_155      GLAAGLGLITALAICVFSVGLLRDHGGDVLFYPPAVISVVLAGACLGFLP
TH_1564|M.thermoresistible__bu      GLAAGLGLITASAICIFSIGLLRDHGGDVLFYPPAVISVVLAGACLGFLP
Rv1302|M.tuberculosis_H37Rv         GLAAGLGLITALAICMFSVGLLRDHGGDVLYYPPAVISVVLAGACLGFLP
Mb1334|M.bovis_AF2122/97            GLAAGLGLITALAICMFSVGLLRDHGGDVLYYPPAVISVVLAGACLGFLP
MAV_1519|M.avium_104                GLAAGLGLITALAICMFSVGLLRDHGGDVLFYPPAVISVVLAGACLGFLP
MMAR_4095|M.marinum_M               GLAAGLGLITALAICTFSVGLLRDHGGDVLFYPPAVISVVLAGACLGFLP
MUL_3962|M.ulcerans_Agy99           GLAAGLGLITALAICTFSVGLLRDHGGDVLFYPPAVISVVLAGACLGFLP
MLBr_01137|M.leprae_Br4923          GLAAGLGLITAMAICIFSVGLLRDHDGDVLFYPPAVISVVLAGSCLGFLP
MAB_1445|M.abscessus_ATCC_1997      GLAAGLGLITAAAICIFSIGLLRSHGGDVLYYPPAVISVVLAGACLGFLP
                                    *********** *** **:***:.*.****:************ ******

Mflv_2310|M.gilvum_PYR-GCK          HNFHKARIFMGDSGSMLIGLMLAAAATTAAGPISQTAYGARDVFALLSPF
Mvan_4336|M.vanbaalenii_PYR-1       HNFHKARIFMGDSGSMLIGLMLAAASTTAAGPISQTAYGARDVFALLSPF
MSMEG_4947|M.smegmatis_MC2_155      HNFHRAKIFMGDSGSMLIGLMLGAASTTAAGPISQNAYGARDVFALLSPF
TH_1564|M.thermoresistible__bu      HNFHRAKIFMGDSGSMLIGLMLAAASTTAAGPISQSAYGARDVFALLSPF
Rv1302|M.tuberculosis_H37Rv         HNFHRAKIFMGDSGSMLIGLMLAAASTTAAGPISQNAYGARDVFALLSPF
Mb1334|M.bovis_AF2122/97            HNFHRAKIFMGDSGSMLIGLMLAAASTTAAGPISQNAYGARDVFALLSPF
MAV_1519|M.avium_104                HNFHRAKIFMGDSGSMLIGLMLAAASTTAAGPVSQNAYGARDVFALLSPF
MMAR_4095|M.marinum_M               HNFHRAKIFMGDSGSMLVGLMLAAASTTAAGPISQNAYGARDVFALLSPF
MUL_3962|M.ulcerans_Agy99           HNFHRAKIFMGDSGSMLVGLMLAAASTTAAGPISQNAYGARDVFALLSPF
MLBr_01137|M.leprae_Br4923          HNFHRAKIFMGDSGSMLVGLMLAAASTTAAGPISQNAYGTRDVFALLSPF
MAB_1445|M.abscessus_ATCC_1997      HNFHRARIFMGDSGSMLIGLMLAAASTTAAGPISQSSYGAKDMFVLLSPF
                                    ****:*:**********:****.**:******:**.:**::*:*.*****

Mflv_2310|M.gilvum_PYR-GCK          LLVVAVVFVPALDMLLAIIRRTRKGLSPFSPDKMHLHHRLLEIGHSHRRV
Mvan_4336|M.vanbaalenii_PYR-1       LLVVAVMFVPALDMLLAIIRRTRKGLSPFSPDKMHLHHRLLEIGHSHRRV
MSMEG_4947|M.smegmatis_MC2_155      LLVVAVMLVPALDTLLAIVRRTRAGRSPLSPDKMHLHHRLLQIGHSHRRA
TH_1564|M.thermoresistible__bu      LLVIAVVLVPALDMLLAIVRRTRAGRSPFSPDKMHIHHRLLQIGHSHRRV
Rv1302|M.tuberculosis_H37Rv         LLVVAVMFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRV
Mb1334|M.bovis_AF2122/97            LLVVAVMFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRV
MAV_1519|M.avium_104                LLVAAVIFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRV
MMAR_4095|M.marinum_M               LLVVAVMFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRV
MUL_3962|M.ulcerans_Agy99           LLVVAVMFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRV
MLBr_01137|M.leprae_Br4923          LLVVAVMFVPMLDLLLAIVRRIRAGRSAFSPDKMHLHHRLLQIGHSHRRV
MAB_1445|M.abscessus_ATCC_1997      LLVIAVMLVPALDALLAIIRRTRAGRSPFSPDKMHLHHRLLQIGHSHRKA
                                    *** **::** ** ****:** * * *.:******:*****:******:.

Mflv_2310|M.gilvum_PYR-GCK          VLLIYLWVGIVAIGAASTIFVDPKHTAIVMAVAIVVAIVVTLIPLLKRGN
Mvan_4336|M.vanbaalenii_PYR-1       VLLIYLWVGIAALGAASSIFFDPRRTAAVMGGAILIAIVVTLIPLLRRGN
MSMEG_4947|M.smegmatis_MC2_155      VLLIYLWVGIIAFGAASTIFFDPGQTAMVMGVAIVVAIVVTLIPLLRRGP
TH_1564|M.thermoresistible__bu      VLLIYLWVGIVALGAASTIFFDPKHTGAVMLAAIVVALVVTLIPLLRRGS
Rv1302|M.tuberculosis_H37Rv         VLIIYLWVGIVAFGAASSIFFNPRDTAAVMLGAIVVAGVATLIPLLRRGD
Mb1334|M.bovis_AF2122/97            VLIIYLWVGIGAFGAASSIFFNPRDTAAVMLGAIVVAGVATLIPLLRRGD
MAV_1519|M.avium_104                VLLIYLWVGIVAFGAASTIFFRPRDTAAVMLGAIVVAGIATAIPLLRRGD
MMAR_4095|M.marinum_M               VLLIYLWVGIVAFGAASTIFVDPRHTAAVMLGALVVAGVVTAIPLLRRRD
MUL_3962|M.ulcerans_Agy99           VLLIYLWVGIVAFGAASTIFVDPRHTAAVMLGALVVAGVVTAIPLLRRRD
MLBr_01137|M.leprae_Br4923          VLLIYLWVGIVAFGAASTIFFNPRNTGAVMLGAIVITGMATVIPLLRRRD
MAB_1445|M.abscessus_ATCC_1997      VLIIYLWVAIIAFGAASTIFFEPRYAGAVVVGAIGIAIVATVIPLLRRED
                                    **:*****.* *:****:**. *  :. *:  *: :: :.* ****:*  

Mflv_2310|M.gilvum_PYR-GCK          DE-------------ADSVYDEK
Mvan_4336|M.vanbaalenii_PYR-1       SA-------------AAEVYDEK
MSMEG_4947|M.smegmatis_MC2_155      DG-------------AQEP----
TH_1564|M.thermoresistible__bu      ND-------------YEQMYDSK
Rv1302|M.tuberculosis_H37Rv         DY-------------YDPDLD--
Mb1334|M.bovis_AF2122/97            DY-------------YDPDLD--
MAV_1519|M.avium_104                DY-------------EDEEYDRQ
MMAR_4095|M.marinum_M               DY-------------YDPD----
MUL_3962|M.ulcerans_Agy99           DY-------------YDPD----
MLBr_01137|M.leprae_Br4923          NY---------------------
MAB_1445|M.abscessus_ATCC_1997      TDPALATAPDSSPGTEPVVYDEK