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RQILIAVAIAVAVSILLTPVLIRLFTRQGFGHEIREDGPPSHHKKRGTPSMGGVAIVAGIWASYFGTHLV GVVIDGKGPSASGLLVLGLATALGAVGFLDDLIKIRRARNLGLNKTAKTVGILVAAVLFGVLALQFRNVD GLTPGSAELSYVREIATVTLAPAVFVLFCVVVVSAWSNAVNFTDGLDGLAAGAMAMVCAAYVLITFWQFR NACATSPGVGCYNVRDPLDLAIIAAATAGACIGFLWWNAAPAKIFMGDTGSLALGGIIAGLSVTSRTEML AVVLGALFVAEVTSVVVQILAFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFYS EWLTTVGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3526 | mraY | - | 100% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. vanbaalenii PYR-1 | Mvan_4336 | - | 2e-17 | 25.78% (322) | glycosyl transferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2180c | mraY | 0.0 | 86.91% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. gilvum PYR-GCK | Mflv_2985 | mraY | 0.0 | 96.94% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. tuberculosis H37Rv | Rv2156c | mraY | 0.0 | 86.91% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. leprae Br4923 | MLBr_00911 | mraY | 0.0 | 85.79% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. abscessus ATCC 19977 | MAB_2003 | mraY | 1e-172 | 79.61% (358) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. marinum M | MMAR_3196 | mraY | 0.0 | 86.35% (359) | phospho-N-acetylmuramoyl- pentappeptidetransferase MurX |
| M. avium 104 | MAV_2333 | mraY | 0.0 | 86.35% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. smegmatis MC2 155 | MSMEG_4230 | mraY | 0.0 | 89.14% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
| M. thermoresistible (build 8) | TH_1328 | - | 0.0 | 91.36% (359) | Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX |
| M. ulcerans Agy99 | MUL_3504 | mraY | 0.0 | 86.07% (359) | phospho-N-acetylmuramoyl-pentapeptide-transferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3526|M.vanbaalenii_PYR-1 MRQILIAVAIAVAVSILLTPVLIRLFTRQGFGHEIREDGPPSHHKKRGTP
Mflv_2985|M.gilvum_PYR-GCK MRQILIAVAIALAVAILLTPVLIRLFTRQGFGHEIREDGPPSHHKKRGTP
TH_1328|M.thermoresistible__bu MRQILIAAGIALAVSILLTPALIRLFTRQGFGHEIREDGPPSHHKKRGTP
MSMEG_4230|M.smegmatis_MC2_155 MMLILIAVGIALAVSILLTPALIRLFTKQGLGHEIREDGPPSHAKKRGTP
MLBr_00911|M.leprae_Br4923 MRQILVAVTVALVVSILLTPALIRLFTRHGFGQEIREDGPPSHHNKRGTP
MAV_2333|M.avium_104 MRQILIAVAIALTVSILLTPALIRLFTRQGFGHHTREDGPPTHHAKRGTP
Mb2180c|M.bovis_AF2122/97 MRQILIAVAVAVTVSILLTPVLIRLFTKQGFGHQIREDGPPSHHTKRGTP
Rv2156c|M.tuberculosis_H37Rv MRQILIAVAVAVTVSILLTPVLIRLFTKQGFGHQIREDGPPSHHTKRGTP
MMAR_3196|M.marinum_M MRQIMIAVAIAVAVSILLTPALIRLFTKQGFGHQIREDGPPSHHSKRGTP
MUL_3504|M.ulcerans_Agy99 MRQIMIAVAIAVAVSILLTPALIRLFTKQGFGHQIREDGPPSHHSKRGTP
MAB_2003|M.abscessus_ATCC_1997 MRQIIIAAGIAILVSIMLTPVLIRVFSRQGFGQEIRDDGPQHHQKKRGTP
* *::*. :*: *:*:***.***:*:::*:*:. *:*** * *****
Mvan_3526|M.vanbaalenii_PYR-1 SMGGVAIVAGIWASYFGTHLVGVVIDGKGPSASGLLVLGLATALGAVGFL
Mflv_2985|M.gilvum_PYR-GCK SMGGVAIIAGIWVSYFGTHLVGVLMDGKGPSASGLLVLGLATSLGVVGFL
TH_1328|M.thermoresistible__bu SMGGVAILAGMWASYLGTHLVGIALDGRGPSASGLLVLGLATALGLVGFI
MSMEG_4230|M.smegmatis_MC2_155 SMGGVAILAGIWAGYLGSHLVGMAMGGDGPSASGLLVLGLATVLGGVGFI
MLBr_00911|M.leprae_Br4923 SMGGVAIVAGIWAGYLGTHLAGLAFDGEGVSASGVLVLGLATALGGVGFL
MAV_2333|M.avium_104 SMGGVAIIAGIWAGYLGTHLAGLAFDGEGISASGLLVLSLATVLGIVGFL
Mb2180c|M.bovis_AF2122/97 SMGGVAILAGIWAGYLGAHLAGLAFDGEGIGASGLLVLGLATALGGVGFI
Rv2156c|M.tuberculosis_H37Rv SMGGVAILAGIWAGYLGAHLAGLAFDGEGIGASGLLVLGLATALGGVGFI
MMAR_3196|M.marinum_M SMGGVAILAGIWAGYFGTHLAGLAFDGEGITASGLLVLGLATSLGGVGFL
MUL_3504|M.ulcerans_Agy99 SMGGVAILAGIWAGYFGTHLAGLAFDGEGITASGLLVLGLATSLGGVGFL
MAB_2003|M.abscessus_ATCC_1997 SMGGVAILAGMWAGYFGSHLVGIAFGSDGPSASGLLVLALATMLGGVGFI
*******:**:*..*:*:**.*: :.. * ***:***.*** ** ***:
Mvan_3526|M.vanbaalenii_PYR-1 DDLIKIRRARNLGLNKTAKTVGILVAAVLFGVLALQFRNVDGLTPGSAEL
Mflv_2985|M.gilvum_PYR-GCK DDLIKLRRARNLGLNKTAKTVGILVAAVLFGVLALQFRNADGLTPGSAEL
TH_1328|M.thermoresistible__bu DDLIKIRRARNLGLNKTAKTVGILLAAVAFGVLALQFRNADGLTPGAAEL
MSMEG_4230|M.smegmatis_MC2_155 DDMIKLKRARNLGLNKTAKTVGQLFAAVLFGVLALQFRNGDGLTPGSAEL
MLBr_00911|M.leprae_Br4923 DDLIKIRRSRNLGLNKTAKTVGQITAAVLFGVLVLQFRNGAGLTPASADL
MAV_2333|M.avium_104 DDLIKIRRSRNLGLNKTAKTIGQVAAAVLFGVLALGFRNANGLTPASADL
Mb2180c|M.bovis_AF2122/97 DDLIKIRRSRNLGLNKTAKTVGQITSAVLFGVLVLQFRNAAGLTPGSADL
Rv2156c|M.tuberculosis_H37Rv DDLIKIRRSRNLGLNKTAKTVGQITSAVLFGVLVLQFRNAAGLTPGSADL
MMAR_3196|M.marinum_M DDLIKLRRSRNLGLNKTAKTVGQITSAVLFAVLVLQFRNPAGLAPASAEL
MUL_3504|M.ulcerans_Agy99 DDMIKLRRSRNLGLNKTAKTVGQITSAVLFAVLVLQFRNPAGLAPASAEL
MAB_2003|M.abscessus_ATCC_1997 DDFIKIRKARNLGLNKTSKTVGQILSALVFGVLVLQFRNTDGLTPGSPQL
**:**::::********:**:* : :*: *.**.* *** **:*.:.:*
Mvan_3526|M.vanbaalenii_PYR-1 SYVREIATVTLAPAVFVLFCVVVVSAWSNAVNFTDGLDGLAAGAMAMVCA
Mflv_2985|M.gilvum_PYR-GCK SYVREIATVTLAPAVFVLFCVVVVSAWSNAVNFTDGLDGLAAGAMAMVCA
TH_1328|M.thermoresistible__bu SYVREIATVTMPYLVFVLFCVLVISAWSNAVNFTDGLDGLAAGAMAMVCA
MSMEG_4230|M.smegmatis_MC2_155 SYVREIATVTLAPALFVLFCVVVVSAWSNAVNFTDGLDGLAAGAMAMVTA
MLBr_00911|M.leprae_Br4923 SYVREIATVTLAPALFVLFCMVIVSAWSNAVNFTDGLDGLAAGSMAMVTA
MAV_2333|M.avium_104 SYVREIATVTLAPGLFVLFCVVVVSAWSNAVNFTDGLDGLAAGSMAMVTA
Mb2180c|M.bovis_AF2122/97 SYVREIATVTLAPVLFVLFCVVIVSAWSNAVNFTDGLDGLAAGTMAMVTA
Rv2156c|M.tuberculosis_H37Rv SYVREIATVTLAPVLFVLFCVVIVSAWSNAVNFTDGLDGLAAGTMAMVTA
MMAR_3196|M.marinum_M SYVREIATVTLTPALFVLFCVLVVSAWSNAVNFTDGLDGLAAGCMAMVTG
MUL_3504|M.ulcerans_Agy99 SYVREIATVTLTPALFVLFCVLVVSAWSNAVNFTDGLDGLAAGCMAMVTG
MAB_2003|M.abscessus_ATCC_1997 SYVREIATVAMPAAIFVLFCVILVMSWSNAVNFTDGLDGLAGGCMAMVTG
*********::. :*****:::: :***************.* **** .
Mvan_3526|M.vanbaalenii_PYR-1 AYVLITFWQFRNACATSPGVGCYNVRDPLDLAIIAAATAGACIGFLWWNA
Mflv_2985|M.gilvum_PYR-GCK AYVLITFWQFRNACATAPGVGCYNVRDPLDLAIIAAATAGACIGFLWWNA
TH_1328|M.thermoresistible__bu AYVLITFWQYRNACATSPDLGCYNVRDPLDLAIVAAATAGACIGFLWWNA
MSMEG_4230|M.smegmatis_MC2_155 AYVLITFWQYRNACATAPGLGCYNVRDPLDLALVAAATAGACVGFLWWNA
MLBr_00911|M.leprae_Br4923 AYVLITFWQYRNACVTAPGLGCYNVRDPLDLTLIAAATVGACIGFLWWNA
MAV_2333|M.avium_104 AYVLITFWQYRNACVTAPGLGCYNVRDPLDLAIVAAATAGACIGFLWWNA
Mb2180c|M.bovis_AF2122/97 AYVLITFWQYRNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
Rv2156c|M.tuberculosis_H37Rv AYVLITFWQYRNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
MMAR_3196|M.marinum_M AYVLITFWQDHNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
MUL_3504|M.ulcerans_Agy99 AYVLITFWQDHNACVTAPGLGCYNVRDPLDLALIAAATAGACIGFLWWNA
MAB_2003|M.abscessus_ATCC_1997 AYVIVTFWQYRNACSTHPGIACYNVRDPLDLAVIAAATAGACIGFLWWNA
***::**** :*** * *.:.**********:::****.***:*******
Mvan_3526|M.vanbaalenii_PYR-1 APAKIFMGDTGSLALGGIIAGLSVTSRTEMLAVVLGALFVAEVTSVVVQI
Mflv_2985|M.gilvum_PYR-GCK APAKIFMGDTGSLALGGIIAGLSVTSRTEMLAVVLGALFVAEVTSVVVQI
TH_1328|M.thermoresistible__bu APAKIFMGDTGSLALGGIIAGLSVTSRTEILAIVLGALFVAEVTSVVVQI
MSMEG_4230|M.smegmatis_MC2_155 APAKIFMGDTGSLALGGIIAGISVTSRTEILAVVLGALFVAEVTSVVVQI
MLBr_00911|M.leprae_Br4923 APAKVFMGDTGSLALGGVIAGLSVTSRTEILAVVLGSLFVAEITSVVLQI
MAV_2333|M.avium_104 APAKIFMGDTGSLALGGIIAGISVTSRTEILAVVLGSLFVAEVSSVVLQI
Mb2180c|M.bovis_AF2122/97 APAKIFMGDTGSLALGGVIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
Rv2156c|M.tuberculosis_H37Rv APAKIFMGDTGSLALGGVIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
MMAR_3196|M.marinum_M APAKIFMGDTGSLALGGIIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
MUL_3504|M.ulcerans_Agy99 APAKIFMGDTGSLALGGIIAGLSVTSRTEILAVVLGALFVAEITSVVLQI
MAB_2003|M.abscessus_ATCC_1997 APAKIFMGDTGSLALGGVIAGLSVTTRTELLAVVLGALFVAEIVSVVLQI
****:************:***:***:***:**:***:*****: ***:**
Mvan_3526|M.vanbaalenii_PYR-1 LAFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFY
Mflv_2985|M.gilvum_PYR-GCK LAFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFY
TH_1328|M.thermoresistible__bu LVFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFY
MSMEG_4230|M.smegmatis_MC2_155 LAFRTTGRRVFRMAPFHHHFELVGWAETQVIIRFWLLTAIACGLGVALFY
MLBr_00911|M.leprae_Br4923 LAFRTTGRRVFRMAPFHHHFELAGWAETTVIIRFWLLTAIACGLGVVLFY
MAV_2333|M.avium_104 LTFRTTGRRVFRMAPFHHHFELAGWAETTVIIRFWLLTAIACGLGVALFY
Mb2180c|M.bovis_AF2122/97 LTFRTTGRRMFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
Rv2156c|M.tuberculosis_H37Rv LTFRTTGRRMFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
MMAR_3196|M.marinum_M LTFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
MUL_3504|M.ulcerans_Agy99 LTFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAITCGLGVALFY
MAB_2003|M.abscessus_ATCC_1997 AAFRTTGRRVFRMAPFHHHFELLGWAETTVIIRFWLLTAIACGLGLALFY
.*******:************ ***** ***********:****:.***
Mvan_3526|M.vanbaalenii_PYR-1 SEWLTTVGA
Mflv_2985|M.gilvum_PYR-GCK SEWLTTVGA
TH_1328|M.thermoresistible__bu GEWLTTVGA
MSMEG_4230|M.smegmatis_MC2_155 GEWLTAVGA
MLBr_00911|M.leprae_Br4923 GEWLATIGA
MAV_2333|M.avium_104 GEWLAAIGA
Mb2180c|M.bovis_AF2122/97 GEWLAAVGA
Rv2156c|M.tuberculosis_H37Rv GEWLAAVGA
MMAR_3196|M.marinum_M GEWLAAIGA
MUL_3504|M.ulcerans_Agy99 GEWLAAIGA
MAB_2003|M.abscessus_ATCC_1997 GEWLATIGD
.***:::*