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M. smegmatis MC2 155 MSMEG_3860 (-)

annotation: polyprenol-monophosphomannose synthase Ppm1
coordinates: 3930485 - 3932332
length: 615

ADDRARRFDRFRVRPEEITEVIPAVTDDDPLEDPLDDDVAPGLDDAEPEPEPRDEHDEPSRPATGSRIGG
WVARRGSRFGKGVLDRCAPLSAAIGGGLALWLSFPPIGWWFTAFPGLALLGWVLTRTATTKAGGFGYGVL
FGLAFYVPLLPWISGLVGAVPWLALAFAESLFCGLFGLGAVVVVRLPGWPLWFATLWVAAEWAKSTFPFG
GFPWGASSYGQTNGPLLALARIGGAPLVSFAVALIGFSLTLLTAQIVWWWRHGHKPGVPAPAVMLPGVAI
AASLLVTALVWPQVRQSGTGAGDDTAVTVAAVQGNVPRLGLEFNAQRRAVLDNHVKETLRLADDVKAGRA
AQPMFVIWPENSSDIDPLLNADASAQITTAAEAIDAPILVGGVVRADGYTPDNPVANNTVIVWEPTDGPG
ERHDKQIVQPFGEYLPWRGFFKHLSSYADRAGYFVPGTGTGVVHAAGVPIGITTCWEVIFDRAARESVLN
GAQVLAVPSNNATFDEAMSAQQLAFGKLRAVEHDRYVVVAGTTGISAVIAPDGHEISRTEWFQPAYLDNQ
IRLKTDLTPATKWGPIVQAVLVIAGVAVLLIAILHNGRFAPRMLRRRSATTVKR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3860--100% (615)polyprenol-monophosphomannose synthase Ppm1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2077cppm10.062.52% (539) polyprenol-monophosphomannose synthase Ppm1
M. gilvum PYR-GCKMflv_3117-0.069.04% (562) apolipoprotein N-acyltransferase
M. tuberculosis H37RvRv2051cppm10.062.52% (539) polyprenol-monophosphomannose synthase Ppm1
M. leprae Br4923MLBr_01441-0.060.84% (526) putative apolipoprotein N-acyltransferase
M. abscessus ATCC 19977MAB_2206-0.058.69% (581) polyprenol-phosphate-mannose synthase 2
M. marinum MMMAR_3029ppm1A0.056.80% (618) polyprenol-monophosphomannose synthase, Ppm1A
M. avium 104-----
M. thermoresistible (build 8)TH_0732-0.066.95% (590) Polyprenol-monophosphomannose synthase Ppm1
M. ulcerans Agy99MUL_5127ppm1A0.061.22% (539) N-term polyprenol-monophosphomannose synthase Ppm1A
M. vanbaalenii PYR-1Mvan_3419-0.071.00% (538) apolipoprotein N-acyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3117|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3419|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0732|M.thermoresistible__bu      ---------------------MADRGRRDRRAPGRRSGPTSGPTSGPTSG
MSMEG_3860|M.smegmatis_MC2_155      ---------------------MADDRARRFDRFRVRPEEITEVIPAVTD-
MAB_2206|M.abscessus_ATCC_1997      ---------------------MADETVEES-VAETRGDEVADLG------
Mb2077c|M.bovis_AF2122/97           --------------------------------------------------
Rv2051c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3029|M.marinum_M               MARDWLGRERLPVDAQEDNPEVVQPEPGVDQTGPLGDEREPDADTADPGD
MUL_5127|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01441|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_3117|M.gilvum_PYR-GCK          -----------------------------------------MGETAADAD
Mvan_3419|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0732|M.thermoresistible__bu      PASGPTRSEPPTDPIGFDPITDDPAEDPAEDPAEDPAGDDPVEDPATDEP
MSMEG_3860|M.smegmatis_MC2_155      ---------------------DDPLEDPLDDDVAP--GLDDAEPEPEPRD
MAB_2206|M.abscessus_ATCC_1997      ---------------------GERTEDSIAD---------EPEAPAETGP
Mb2077c|M.bovis_AF2122/97           -------------------------------------------------M
Rv2051c|M.tuberculosis_H37Rv        -------------------------------------------------M
MMAR_3029|M.marinum_M               DAAIADDLAEEQDEAQDEAQDSETEAETTQVSAGPSAAVRLGTAARQGLV
MUL_5127|M.ulcerans_Agy99           -------------------------------------------------M
MLBr_01441|M.leprae_Br4923          ---------MVDEIIEIDPVDDDPVNGAFATLAVPSRVVKLRATVCHALA
                                                                                      

Mflv_3117|M.gilvum_PYR-GCK          APERPTRAR-----------------RFGQAVVDRLPRLTAAIVAGLALC
Mvan_3419|M.vanbaalenii_PYR-1       MADTPGRVT-----------------RLVRAVADRWHVLSLTIAAGLLLC
TH_0732|M.thermoresistible__bu      ATDEPSRADTAEPGDRPADRLIRFAHRAGRAVLDRLPQLGLTVLAGLLLC
MSMEG_3860|M.smegmatis_MC2_155      EHDEPSRPATG---SRIGGWVARRGSRFGKGVLDRCAPLSAAIGGGLALW
MAB_2206|M.abscessus_ATCC_1997      SRGKLFAAAVG-----------ARIVAFGRAWMRTATRQGAALIAGLALC
Mb2077c|M.bovis_AF2122/97           KLGAWVAAQLP---------------TTRTAVRTRLTRLVVSIVAGLLLY
Rv2051c|M.tuberculosis_H37Rv        KLGAWVAAQLP---------------TTRTAVRTRLTRLVVSIVAGLLLY
MMAR_3029|M.marinum_M               AFGAGAAARLP---------------GLWAATRPRLVRLVVSLVAGFLMY
MUL_5127|M.ulcerans_Agy99           AFGAGAAARLP---------------GLWAATRPRLVRLVVSLVAGFLMY
MLBr_01441|M.leprae_Br4923          QMGVATVARVP---------------ATWAMLVPRLPRLVVAVVAGLLFC
                                                                             :: .*: : 

Mflv_3117|M.gilvum_PYR-GCK          VSFPPFGWWYIAILAFAVLGWVLTRERTTVAGGAGYGLLFGLAFYVPLLP
Mvan_3419|M.vanbaalenii_PYR-1       ASFPPIGWWFTAILAFAVFGWVLTRNSTTVAGGAGYGLLFGVAFYVPLLP
TH_0732|M.thermoresistible__bu      VSFPPMGWWYLAPVALALLGGVLVHRATTLAGGFGYGVLFGLAFHIPLLP
MSMEG_3860|M.smegmatis_MC2_155      LSFPPIGWWFTAFPGLALLGWVLTRTATTKAGGFGYGVLFGLAFYVPLLP
MAB_2206|M.abscessus_ATCC_1997      ASFPPWGFWWAAFPALSVLGLVLWSPRTTLRGGLGYGLLFGLAFFIPLLP
Mb2077c|M.bovis_AF2122/97           ASFPPRNCWWAAVVALALLAWVLTHRATTPVGGLGYGLLFGLVFYVSLLP
Rv2051c|M.tuberculosis_H37Rv        ASFPPRNCWWAAVVALALLAWVLTHRATTPVGGLGYGLLFGLVFYVSLLP
MMAR_3029|M.marinum_M               ASFPPTNWWWAAIVSVALLTWVLMHPTTTPVGGLGYGFVFGLACFVPLLP
MUL_5127|M.ulcerans_Agy99           ASFPPTNWWWAAIVSVALLTWVLMHPASTPVGGLGYGFVFGLACFVPLLP
MLBr_01441|M.leprae_Br4923          ASFPSLNWWWAAVVAFALLAWVLTHPTTTPVGGLGYGFLFGLAFYLPLLS
                                     ***. . *: *  ..:::  **    :*  ** ***.:**:. .:.**.

Mflv_3117|M.gilvum_PYR-GCK          WISGLVGAVPWLALSVVEALFCALFGMLAVVVRRLPGWPLWFAGLWSAQE
Mvan_3419|M.vanbaalenii_PYR-1       WISGLVGAVPWLALSFAEALFPALFGMAAVAIRRLPGWPLWFAGLWSAQE
TH_0732|M.thermoresistible__bu      WISGLVGAVPWLALSVVQAVFPGLFGLAAVAVRRLPGRPVWFALLWVAYE
MSMEG_3860|M.smegmatis_MC2_155      WISGLVGAVPWLALAFAESLFCGLFGLGAVVVVRLPGWPLWFATLWVAAE
MAB_2206|M.abscessus_ATCC_1997      WTGQLVGAVPWLALSLLCALWVALFGLLAVAVRNLPGWPLWFAAAWSATE
Mb2077c|M.bovis_AF2122/97           WIGELVGPGPWLALATTCALFPGIFGLFAVVVRLLPGWPIWFAVGWAAQE
Rv2051c|M.tuberculosis_H37Rv        WIGELVGPGPWLALATTCALFPGIFGLFAVVVRLLPGWPIWFAVGWAAQE
MMAR_3029|M.marinum_M               WIGTLVGPVPWLVLATTSALFPGLFGLSAVVVRRLPGWPIWFAVLWGAQE
MUL_5127|M.ulcerans_Agy99           WIGTLVGPVPWLVLATTSALFPGLFGLSAVVVRRLPGWPIWFAVLWGAQE
MLBr_01441|M.leprae_Br4923          WISSLVGATPWWALATAAAFLPGFFGLLAVVVGPLPGWPIWFAVVWAAQE
                                    * . ***. ** .*:   :.  .:**: **.:  *** *:***  * * *

Mflv_3117|M.gilvum_PYR-GCK          WLKSTVPFGGFPWGVVGFSQSESPLLPLAYVGGAPLVSFALVLLAFSLGA
Mvan_3419|M.vanbaalenii_PYR-1       WLKSAVPFGGFPWGTVAFSQTESPLLPLAYVGGAPLVSFAVVLLAFSLAA
TH_0732|M.thermoresistible__bu      WIKSSVPFGGFPWGVVAYSQTNGPLLALAQIGGAPLVSFAVALTGFSLAA
MSMEG_3860|M.smegmatis_MC2_155      WAKSTFPFGGFPWGASSYGQTNGPLLALARIGGAPLVSFAVALIGFSLTL
MAB_2206|M.abscessus_ATCC_1997      WGKASIPFGGFPWGRVAFGQGDSPMLGLARYGGAPLVSFAVALGAFAVTA
Mb2077c|M.bovis_AF2122/97           WLKSILPFGGFPWGSVAFGQAEGPLLPLVQLGGVALLSTGVALVGCGLTA
Rv2051c|M.tuberculosis_H37Rv        WLKSILPFGGFPWGSVAFGQAEGPLLPLVQLGGVALLSTGVALVGCGLTA
MMAR_3029|M.marinum_M               WLKSIVPFGGFPWGSVAFGQVDGPLLPLAQLGGVPLLSTGVVLVGSSFAA
MUL_5127|M.ulcerans_Agy99           WLKSIVPFGGFPWGSVAFGQVDGPLLPLAQLGGVPLLSTGVALVGSSFAA
MLBr_01441|M.leprae_Br4923          WLKSVVPFGGFPWGSVAFGQADGPLLPLAQLGGAPLLSMAIVLVGCSTTA
                                    * *: .********  .:.* :.*:* *.  **..*:* .:.* . .   

Mflv_3117|M.gilvum_PYR-GCK          LVLGVADWWRRDAATR------------AATPPAVVLPGLCIAVVVLAST
Mvan_3419|M.vanbaalenii_PYR-1       LVFAVADWWRRDATAR------------AAAPPAVVLPGLCITLVLLAAT
TH_0732|M.thermoresistible__bu      LTAAIVRWWRSDSHR--------------AAPPAVVLPGLCIAAVLLATA
MSMEG_3860|M.smegmatis_MC2_155      LTAQIVWWWR-HGHKP------------GVPAPAVMLPGVAIAASLLVTA
MAB_2206|M.abscessus_ATCC_1997      LGIEMYRWWRSPSVGP----------DGARPMPSVLLPGVCVCLVLFAMA
Mb2077c|M.bovis_AF2122/97           IALEIEKWWRTGG----QGD----------APPAVVLPAACICLVLFAAI
Rv2051c|M.tuberculosis_H37Rv        IALEIEKWWRTGG----QGD----------APPAVVLPAACICLVLFAAI
MMAR_3029|M.marinum_M               IALEIEKWWRTGSPAAPQADPEAAQPVEPAKPPAVLLPGITVCLVLFAAV
MUL_5127|M.ulcerans_Agy99           IALEIEKWWRTGSPAAPQADPEAAQPVEPAKPPAVLLPGITVCLVLFAAV
MLBr_01441|M.leprae_Br4923          IALEVVKWWRSSG----QSN-------RSDPPPAVVLPGVCVCLVLLAVV
                                    :   :  ***  .                   *:*:**.  :   ::.  

Mflv_3117|M.gilvum_PYR-GCK          LAWPHVRKAGLGAGD-EPPVTVAAVQGNVPRLGLEFNAQRRAVLDNHVRE
Mvan_3419|M.vanbaalenii_PYR-1       LAWPNVRKSGLGAGD-EPPVTVAAVQGNVPRLGLDFNAQRRAVLDNHVRE
TH_0732|M.thermoresistible__bu      VVWPQVRYSGAGADAADQPIRVAAVQGNVPRLGLDFNAQRRAVLDNHVRE
MSMEG_3860|M.smegmatis_MC2_155      LVWPQVRQSGTGAGD-DTAVTVAAVQGNVPRLGLEFNAQRRAVLDNHVKE
MAB_2206|M.abscessus_ATCC_1997      ISWQQVRHASHGATD-GRTVTVAAVQGNVPRLGLDFNAQRRAVLDYHVKE
Mb2077c|M.bovis_AF2122/97           VVWPQVRHAGSGSGG-EPTVTVAVVQGNVPRLGLDFNAQRRAVLDNHVEE
Rv2051c|M.tuberculosis_H37Rv        VVWPQVRHAGSGSGG-EPTVTVAVVQGNVPRLGLDFNAQRRAVLDNHVEE
MMAR_3029|M.marinum_M               IVWPQVRHAGAGSGG-EPTITVAVVQGNVPRLGLDFNAQRRAVLDNHVRE
MUL_5127|M.ulcerans_Agy99           IVWPQVRHAGAGSGG-EPTITVAVVQGNVPRLGLDFNAQRRAVLDNHVRE
MLBr_01441|M.leprae_Br4923          VVWPQVRHAGAGSGG-EPVITVAAVQGNVPRLGLDFNAQRRAVLDNHVHE
                                    : * :** :. *:      : **.**********:********** **.*

Mflv_3117|M.gilvum_PYR-GCK          TLRLADDVRAGRVPQPMLVVWPENSSDIDPIANPDAAQEISRAAAAIDAP
Mvan_3419|M.vanbaalenii_PYR-1       TLRLAEDVRAGRAPQPMLVVWPENSSDIDPLANADASREISTAADAINAP
TH_0732|M.thermoresistible__bu      TMRLAEDVRAGRAEQPLFVVWPENSSDIDPLANPDAHQQISAAAAAIRAP
MSMEG_3860|M.smegmatis_MC2_155      TLRLADDVKAGRAAQPMFVIWPENSSDIDPLLNADASAQITTAAEAIDAP
MAB_2206|M.abscessus_ATCC_1997      TVLLAQDVKAGKAPAPQFVVWPENSSDIDPIRNADAAEAINEAAQAIGVP
Mb2077c|M.bovis_AF2122/97           TLRLAADVHAGLAQQPQFVIWPENSSDIDPFVNPDAGQRISAAAEAIGAP
Rv2051c|M.tuberculosis_H37Rv        TLRLAADVHAGLAQQPQFVIWPENSSDIDPFVNPDAGQRISAAAEAIGAP
MMAR_3029|M.marinum_M               TLELAEDVRAGLAPQPQFVIWPEDSSDIDPLINPDAAQQISKAAVAIGAP
MUL_5127|M.ulcerans_Agy99           TLELAEDVRADLAPQPQFVIWPEDSSDIDPLINPDAAQQISKAAVAIGAP
MLBr_01441|M.leprae_Br4923          TLRLAEDVRAGIVPQPQFVIWPENASDIDPLVNGDAGQEITVAAATIDAP
                                    *: ** **:*. .  * :*:***::*****: * **   *. ** :* .*

Mflv_3117|M.gilvum_PYR-GCK          VLVGGVVAAPGYSR---DNPVSNNTVIVWNPETGPSDRHDKRIVQPFGEY
Mvan_3419|M.vanbaalenii_PYR-1       ILVGGVVAAPGYSR---TNPVSNNTVIVWNPETGPGDRHDKRIVQPFGEY
TH_0732|M.thermoresistible__bu      ILVGGVVRAPGYRP---DNPVATNSVLVWDPETGPTDRHDKQIVQPFGEY
MSMEG_3860|M.smegmatis_MC2_155      ILVGGVVRADGYTP---DNPVANNTVIVWEPTDGPGERHDKQIVQPFGEY
MAB_2206|M.abscessus_ATCC_1997      ILVGGVLRHPDSTP---EQPKSINSIIVWDPNTGPGERHDKQIVQPFGEY
Mb2077c|M.bovis_AF2122/97           ILIGTLMDVPGRPR---ENPEWTNTAIVWNPGTGPADRHDKAIVQPFGEY
Rv2051c|M.tuberculosis_H37Rv        ILIGTLMDVPGRPR---ENPEWTNTAIVWNPGTGPADRHDKAIVQPFGEY
MMAR_3029|M.marinum_M               ILVGTVLDAPGSSQKNLENAEYTNTVLVWNPTTGPGDRHDKEIVQPFGEY
MUL_5127|M.ulcerans_Agy99           ILVGTVLDAPGSSQKNLENAEYTNTVLVWNPTTGPGDRHDKEIVQPFGEY
MLBr_01441|M.leprae_Br4923          ILVGTVLDVQGPVP---QAPEYTNTVIVWNPGTGPADRHDKEIVQPFGEY
                                    :*:* ::   .        .   *: :**:*  ** :**** ********

Mflv_3117|M.gilvum_PYR-GCK          LPWRSFFSKLSSYADRAGYFVPGDG--DGVVEAAGIPVGITTCWEVIFDR
Mvan_3419|M.vanbaalenii_PYR-1       LPWRDFFSKLSPYADRAGYFVPGDG--DGVVQAAGVPVGITTCWEVIFDR
TH_0732|M.thermoresistible__bu      LPWRDFFRRLSPYADRAGYFIPVDG--DGVVTAAGVPVGVTTCWEVIFDR
MSMEG_3860|M.smegmatis_MC2_155      LPWRGFFKHLSSYADRAGYFVPGTG--TGVVHAAGVPIGITTCWEVIFDR
MAB_2206|M.abscessus_ATCC_1997      LPWRSFFAHFSEYADRAGYFVPGDG--NGVVTAGGVNIGVATCWEVLFDR
Mb2077c|M.bovis_AF2122/97           LPMPWLFRHLSGYADRAGHFVPGNG--TGVVRIAGVPVGVATCWEVIFDR
Rv2051c|M.tuberculosis_H37Rv        LPMPWLFRHLSGYADRAGHFVPGNG--TGVVRIAGVPVGVATCWEVIFDR
MMAR_3029|M.marinum_M               LPMPWLFRHLSGYADRAGHFVPRPG--SDVVNIAGVPVGVSTCWEVIFDR
MUL_5127|M.ulcerans_Agy99           LPMPWLFRHLSGYADRAGHFVPRPG--SDVVNIAGVPVGVSTCWEVIFDR
MLBr_01441|M.leprae_Br4923          LPMPWLFKRLSKYADRVSHIVPRQSQSSGVVRIAGVPIGVTTCWEVIFDR
                                    **   :* ::* ****..:::*  .   .**  .*: :*::*****:***

Mflv_3117|M.gilvum_PYR-GCK          AARESVRNGAQLLAVPSNNATFDQAMSEQQLAFGRLRAVEHDRYVVVAGT
Mvan_3419|M.vanbaalenii_PYR-1       AARQSVLSGAQFLAVPSNNATFDQAMSEQQLAFGRLRAVEHDRFVVVSGT
TH_0732|M.thermoresistible__bu      AARESVRNGAEVLAVPTNNATFDEAMSEQHLAFARLRAVEHNRYAVVAGT
MSMEG_3860|M.smegmatis_MC2_155      AARESVLNGAQVLAVPSNNATFDEAMSAQQLAFGKLRAVEHDRYVVVAGT
MAB_2206|M.abscessus_ATCC_1997      ALRQSTLNGAEILAVPSNNALFGSAMSEQQLAISKVRAVEHDREVVVVGT
Mb2077c|M.bovis_AF2122/97           APRKSILGGAQLLTVPSNNATFNKTMSEQQLAFAKVRAVEHDRYVVVAGT
Rv2051c|M.tuberculosis_H37Rv        APRKSILGGAQLLTVPSNNATFNKTMSEQQLAFAKVRAVEHDRYVVVAGT
MMAR_3029|M.marinum_M               APRKAVRNGAQLLAVPSNNATFNKTMSEQQLAFAKVRAVEHDRYVVVAGT
MUL_5127|M.ulcerans_Agy99           APRRAVRNGAQLLAVPSNNATFNKTMSEQQLAFAKVRAVEHDRYVVVAGT
MLBr_01441|M.leprae_Br4923          AARKAVLNGAQLLAAPTNNATFNKTMSEQQLAFAKVRAVEHDRYVVVTGT
                                    * *.:  .**:.*:.*:*** *..:** *:**:.::*****:* .** **

Mflv_3117|M.gilvum_PYR-GCK          TGISAVIAPDGHEIVRTGWFEPAYLDQQVRLKTSLTPATRFGPYVEGVLI
Mvan_3419|M.vanbaalenii_PYR-1       TGISAVIAPDGREIARTGWFEPAYLDQQIRLKTRLTPATRFGPYIEAVLV
TH_0732|M.thermoresistible__bu      TGISAVITPDGREVARTRFFEPAYLDVQVRLKTQLSPATRYGPVIHGALI
MSMEG_3860|M.smegmatis_MC2_155      TGISAVIAPDGHEISRTEWFQPAYLDNQIRLKTDLTPATKWGPIVQAVLV
MAB_2206|M.abscessus_ATCC_1997      TGISAFVSPDGVDAGRTTFFEPAYIDMQVRLHNDLTPATQWGPWVEWALA
Mb2077c|M.bovis_AF2122/97           TGISAVIAPDGGELIRTDFFQPAYLDSQVRLKTRLTPATRWGPILQWILV
Rv2051c|M.tuberculosis_H37Rv        TGISAVIAPDGGELIRTDFFQPAYLDSQVRLKTRLTPATRWGPILQWILV
MMAR_3029|M.marinum_M               TGISAVIAPDGRELVRTDFFEPAYLDIQVRLKTRLTPATRWAPILQWLMV
MUL_5127|M.ulcerans_Agy99           TGISAVIAPDGRELVRTDFFEPAYLDIQVRLKTRLTPATRWAPILQWLMV
MLBr_01441|M.leprae_Br4923          TGISSVIAPDGSELVRTDFFVPAYLDMQVRLKAKLTPATCWGLTLQWILV
                                    ****:.::*** :  ** :* ***:* *:**:  *:*** :.  :.  : 

Mflv_3117|M.gilvum_PYR-GCK          ALGVSG----VVGAILHNGSFLPGRLRRRR--------------------
Mvan_3419|M.vanbaalenii_PYR-1       AIGVSG----VLGAMLHNGSFVPARFRGRR--------------------
TH_0732|M.thermoresistible__bu      AAALAGLGAALAGTVLQNGRLVPHALRGRRRAKESHDDGPATRPRHHGQS
MSMEG_3860|M.smegmatis_MC2_155      IAGVAV----LLIAILHNGRFAPRMLRRRS--------------------
MAB_2206|M.abscessus_ATCC_1997      LIAGLAVLASAGLAILHNGGLKRPEPEVEP--------------------
Mb2077c|M.bovis_AF2122/97           GAAAAV----VLVAMRQNGWFPRP--RRSEPKGENDD-------------
Rv2051c|M.tuberculosis_H37Rv        GAAAAV----VLVAMRQNGWFPRP--RRSEPKGENDD-------------
MMAR_3029|M.marinum_M               GAAGVL----ILVAMRHNGWFPRPTRRRSGPAGEADQ-------------
MUL_5127|M.ulcerans_Agy99           GAAGVL----ILVAMRHNGWFPRPTRRRSGPAGEADQ-------------
MLBr_01441|M.leprae_Br4923          GTAGAI----VLAAMRHN---NGSRSRIVLGLGSSAS-------------
                                      .          :: :*        .                       

Mflv_3117|M.gilvum_PYR-GCK          ------------------PTSDDGEGAT----------------------
Mvan_3419|M.vanbaalenii_PYR-1       ------------------PTTDDDEGAT----------------------
TH_0732|M.thermoresistible__bu      TSESAHSGDHPDLQRTGQSAADRGSGASGLPRGARADRRRRQPRRHR---
MSMEG_3860|M.smegmatis_MC2_155      ------------------ATTVKR--------------------------
MAB_2206|M.abscessus_ATCC_1997      ------------------ASPTKET-------------------------
Mb2077c|M.bovis_AF2122/97           -----------------SDAPPGRSEASGPPALSESDDELIQPEQGGRHS
Rv2051c|M.tuberculosis_H37Rv        -----------------SDAPPGRSEASGPPALSESDDELIQPEQGGRHS
MMAR_3029|M.marinum_M               -----------------SDAPQDEADDSGAASRNESEDDLQ---------
MUL_5127|M.ulcerans_Agy99           -----------------SDAPQDEADDSGATSRNESEDDLQ---------
MLBr_01441|M.leprae_Br4923          -----------------LKTRVRQANVREALTLRLGDRPLIHLSR-----
                                                       :                              

Mflv_3117|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3419|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0732|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3860|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2206|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2077c|M.bovis_AF2122/97           SGFGRHRATSRSYMTTGQPAPPAPGNRPSQRVLVIIPTFNERENLPVIHR
Rv2051c|M.tuberculosis_H37Rv        SGFGRHRATSRSYMTTGQPAPPAPGNRPSQRVLVIIPTFNERENLPVIHR
MMAR_3029|M.marinum_M               ---------------TATGTPPEAGGHHST--------------------
MUL_5127|M.ulcerans_Agy99           ---------------TATGTPPEAGGHHST--------------------
MLBr_01441|M.leprae_Br4923          ------LVTTLRSIYKGGQKPRYFGRHKGAK-------------------
                                                                                      

Mflv_3117|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3419|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0732|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3860|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2206|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2077c|M.bovis_AF2122/97           RLTQACPAVHVLVVDDSSPDGTGQLADELAQADPGRTHVMHRTAKNGLGA
Rv2051c|M.tuberculosis_H37Rv        RLTQACPAVHVLVVDDSSPDGTGQLADELAQADPGRTHVMHRTAKNGLGA
MMAR_3029|M.marinum_M               --------------------------------------------------
MUL_5127|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01441|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_3117|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3419|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0732|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3860|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2206|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2077c|M.bovis_AF2122/97           AYLAGFAWGLSREYSVLVEMDADGSHAPEQLQRLLDAVDAGADLAIGSRY
Rv2051c|M.tuberculosis_H37Rv        AYLAGFAWGLSREYSVLVEMDADGSHAPEQLQRLLDAVDAGADLAIGSRY
MMAR_3029|M.marinum_M               --------------------------------------------------
MUL_5127|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01441|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_3117|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3419|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0732|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3860|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2206|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2077c|M.bovis_AF2122/97           VAGGTVRNWPWRRLVLSKTANTYSRLALGIGIHDITAGYRAYRREALEAI
Rv2051c|M.tuberculosis_H37Rv        VAGGTVRNWPWRRLVLSKTANTYSRLALGIGIHDITAGYRAYRREALEAI
MMAR_3029|M.marinum_M               --------------------------------------------------
MUL_5127|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01441|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_3117|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3419|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0732|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3860|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2206|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2077c|M.bovis_AF2122/97           DLDGVDSKGYCFQIDLTWRTVSNGFVVTEVPITFTERELGVSKMSGSNIR
Rv2051c|M.tuberculosis_H37Rv        DLDGVDSKGYCFQIDLTWRTVSNGFVVTEVPITFTERELGVSKMSGSNIR
MMAR_3029|M.marinum_M               --------------------------------------------------
MUL_5127|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01441|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_3117|M.gilvum_PYR-GCK          --------------------------------------------
Mvan_3419|M.vanbaalenii_PYR-1       --------------------------------------------
TH_0732|M.thermoresistible__bu      --------------------------------------------
MSMEG_3860|M.smegmatis_MC2_155      --------------------------------------------
MAB_2206|M.abscessus_ATCC_1997      --------------------------------------------
Mb2077c|M.bovis_AF2122/97           EALVKVARWGIEGRLSRSDHARARPDIARPGAGGSRVSRADVTE
Rv2051c|M.tuberculosis_H37Rv        EALVKVARWGIEGRLSRSDHARARPDIARPGAGGSRVSRADVTE
MMAR_3029|M.marinum_M               --------------------------------------------
MUL_5127|M.ulcerans_Agy99           --------------------------------------------
MLBr_01441|M.leprae_Br4923          --------------------------------------------