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GWADRIVHRHFIRGLALYAGLIGIAWCALFPIIWALSGSLKADGEVTEPTLFPSHPQWSNYREVFALMPF WRMFFNTVLYAGCVTAGQVFFCSLAGYAFARLQFRGRDTLFVLYLSTLMVPLTVTVIPQVILMRIVGWVD TPWAMIVPGLFGSAFGTYLMRQFFRTLPTDLEEAAILDGCSPWQIYWRILLPHSRPAVLVLGVLTWVNVW NDFLWPLLMIQRNSLATLTLGLVRLRGEYVARWPVLMAASMLMLVPLVILYAVAQRSFVRGIAVTGLGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2039c | - | - | 100% (280) | Probable sugar-transport integral membrane protein ABC transporter |
| M. tuberculosis H37Rv | Rv2317 | uspB | 2e-47 | 37.69% (268) | sugar-transport integral membrane protein ABC transporter |
| M. tuberculosis H37Rv | Rv2834c | ugpE | 4e-39 | 32.10% (271) | sn-glycerol-3-phosphate transport integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2065c | - | 1e-165 | 99.64% (280) | sugar-transport integral membrane protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_3853 | - | 1e-33 | 30.83% (266) | binding-protein-dependent transport systems inner membrane |
| M. leprae Br4923 | MLBr_01425 | - | 1e-136 | 79.15% (283) | putative ABC-transport protein, inner membrane component |
| M. abscessus ATCC 19977 | MAB_1716c | - | 1e-52 | 40.82% (267) | sugar ABC transporter, permease protein |
| M. marinum M | MMAR_3012 | - | 1e-144 | 85.36% (280) | sugar ABC transporter |
| M. avium 104 | MAV_2478 | - | 1e-138 | 80.71% (280) | sugar ABC transporter, permease |
| M. smegmatis MC2 155 | MSMEG_0517 | - | 2e-56 | 40.74% (270) | sugar binding-protein dependent transporter system permease |
| M. thermoresistible (build 8) | TH_2867 | - | 3e-28 | 28.68% (258) | PUTATIVE binding-protein-dependent transport systems inner |
| M. ulcerans Agy99 | MUL_2253 | - | 1e-143 | 84.29% (280) | sugar ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_2542 | - | 3e-33 | 30.08% (266) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2039c|M.tuberculosis_H37Rv MGWADR------------------IVHRHFIRG--LALYAGLIGIAWCAL
Mb2065c|M.bovis_AF2122/97 MGWADR------------------IVHRHFIRG--LALYAGLIGIAWCAL
MMAR_3012|M.marinum_M MGSADR------------------VVQRKIVRA--VALYAALIAIAWCAL
MUL_2253|M.ulcerans_Agy99 MGSADR------------------VVQRNIVRA--VALYAALIAIAWCAM
MLBr_01425|M.leprae_Br4923 MGLAERLNH---------------IVKRSVLRA--VVVYIALTGIAWCAL
MAV_2478|M.avium_104 MGSSEA------------------VIKRTVLRA--ATVYAALLGIAWCAL
MSMEG_0517|M.smegmatis_MC2_155 MTTTPHITAPVAESTEPTVVEDFSPRRRTRLRLPFSPWHLVLIPVTFLLI
MAB_1716c|M.abscessus_ATCC_199 MTWSRN-----------------------------VLVYLLLTVGAVLTL
Mflv_3853|M.gilvum_PYR-GCK ------------------------------MTKNTKWWTIAGIVIVIYSF
Mvan_2542|M.vanbaalenii_PYR-1 ------------------------------MTKNTKWWTIAGIVIVIYSF
TH_2867|M.thermoresistible__bu -------------------------VNERVTARRATGWIVIDLLVILYAL
:
Rv2039c|M.tuberculosis_H37Rv FPIIWALSGSLKADGEVT--EPTLFPSHPQWSNYREVFALM----PFWRM
Mb2065c|M.bovis_AF2122/97 FPIIWALSGSLKADGEVT--EPTLFPSHPQWSNYREVFALM----PFWRM
MMAR_3012|M.marinum_M FPILWALSGSLKKSGEVS--EPRLLPSDPQWSNYAEVFTLM----PFWRM
MUL_2253|M.ulcerans_Agy99 FPILWALSGSLKKGGEVS--EPRLLPSDPQWSNYAEVFTLM----PFWRM
MLBr_01425|M.leprae_Br4923 FPIVWALSGSLKKEGEIR--EPTLLPAHPQWSNYTEVFDLI----PFWRM
MAV_2478|M.avium_104 FPIAWAVSGSLKTEGEVS--EPTLVPARPRWSNYTEVFALM----PIGRM
MSMEG_0517|M.smegmatis_MC2_155 LPLLWMLVTSLQTEGEANRFPPVLLPESPRFENYTEAWATA----PFGHF
MAB_1716c|M.abscessus_ATCC_199 GPFLLAVSASLKTAKQFATGTPLAPPNPFTLANYTG-LADA----GFGRA
Mflv_3853|M.gilvum_PYR-GCK VPMLWMISLAFKPPSDIVSGEPSFLPSTVTFDNFAQIFS---NPL-FTRA
Mvan_2542|M.vanbaalenii_PYR-1 VPMLWMISLAFKPPSDIVSGKPSFLPSSITFDNFAQIFS---QPL-FTRA
TH_2867|M.thermoresistible__bu FPVLWILSLSLKSTATVKDGK--LIPDEITFDNYKAIFRGGGSGV-FTSA
*. : ::: * *: :
Rv2039c|M.tuberculosis_H37Rv FFNTVLYAGCVTAGQVFFCSLAGYAFARLQFRGRDTLFVLYLSTLMVPLT
Mb2065c|M.bovis_AF2122/97 FFNTVLYAGCVTAGQVFFCSLAGYAFARLQFRGRDTLFVLYLSTLMVPLT
MMAR_3012|M.marinum_M FFNTVLYAGCVTAGQIFFCSLAGYAFARLEFRGRDTLFVLYLGTLMVPLT
MUL_2253|M.ulcerans_Agy99 FFNTVLYAGCVTAGQIFFCSLAGYAFARLEFRGRDTLFVLYLGTLMVPLT
MLBr_01425|M.leprae_Br4923 FFNTVLYAGYVTVGQVFFCSLAGYAFARLQFRGRDALFVLYLGTLMMPLT
MAV_2478|M.avium_104 FVNTVLYAGCVTAGHVFFCSLAGYAFARLDFRGRNTLFVVYLGTLMVPLT
MSMEG_0517|M.smegmatis_MC2_155 FLNSFAVTGVVLVSNLVVCSLAGYAFARIRFLGRGALFITLMATLMVPFQ
MAB_1716c|M.abscessus_ATCC_199 ALVTVLMTAIIVIGQLTFSVLAAYAFARLRFPGRDGLFWIYLATLMIPAT
Mflv_3853|M.gilvum_PYR-GCK LINSIGIALVATVISVIIAMFAAYAIARLEFPGKKVLLSLALGIAMFPQA
Mvan_2542|M.vanbaalenii_PYR-1 LINSIGIAVIATVISVIIAMFAAYAIARLEFPGKKVLLSLALGIAMFPQA
TH_2867|M.thermoresistible__bu LINSIGIGLITTVIAVVVGGMAAYAVARLNFPGKRLLIGVALLIAMFPQI
. :. : . :*.**.**: * *: *: : *.*
Rv2039c|M.tuberculosis_H37Rv VTVIPQVILMRIVG-------WVDTPWAMIVPG-LFGSAFGTYLMRQFFR
Mb2065c|M.bovis_AF2122/97 VTVIPQFILMRIVG-------WVDTPWAMIVPG-LFGSAFGTYLMRQFFR
MMAR_3012|M.marinum_M VTVIPQFILMRTVG-------LVDTPWAMIVPG-LFGSAFGTYLMRQFFR
MUL_2253|M.ulcerans_Agy99 VTVIPHFILMRTVG-------LVDTPWAMIVPG-LFGSAFGTYLMRQFFR
MLBr_01425|M.leprae_Br4923 VTIIPQFILMRVLG-------WTDTPWAMIVPG-LFGSAFGTYLMRQFFR
MAV_2478|M.avium_104 VTVIPQFLIMRTLG-------WVDTPWAMIVPG-FFGSAFGTYLMRQFFR
MSMEG_0517|M.smegmatis_MC2_155 VTMIPVFLIVKWFGDNVWEGLGINHIGALMLP--NLATAFGIFFLRQFFL
MAB_1716c|M.abscessus_ATCC_199 VTVVPMYLMLTQVG-------LRNTFWALVIPF-MFGSPYAIFLLREHFR
Mflv_3853|M.gilvum_PYR-GCK ALVGPLFDMWRGLG-------IYDTWLGLIIPYLTFALPLSIWTMSAFFR
Mvan_2542|M.vanbaalenii_PYR-1 ALVGPLFDMWRGLG-------IYDTWLGLIIPYLTFALPLSIWTMSAFFR
TH_2867|M.thermoresistible__bu SLVTPLFNIERQLG-------LFDTWAGLIIPYITFALPLAIYTLSAFFR
: * : .* : .:::* :. . . : : .*
Rv2039c|M.tuberculosis_H37Rv TLPTDLEEAAILDGCSPWQIYWRILLPHSRPAVLVLGVLTWVNVWNDFLW
Mb2065c|M.bovis_AF2122/97 TLPTDLEEAAILDGCSPWQIYWRILLPHSRPAVLVLGVLTWVNVWNDFLW
MMAR_3012|M.marinum_M TLPSDLEEAATLDGCSPWQIYWRILLPHARPAVMVLGVLTWVNVWNDFLW
MUL_2253|M.ulcerans_Agy99 TLPSDLEKAATLDGCSPWQIYWRILLPHARPAVMVLGVLTWVNVWNDFLW
MLBr_01425|M.leprae_Br4923 TLPSDLEEAAILDGCSPWQIYWRVLLPHAKPAVGVLAVLTWVNVWNDFLW
MAV_2478|M.avium_104 TLPTDLEEAAILDGCTPWQVYWRILLPHARPAVMVLAVLTWVNVWNDFLW
MSMEG_0517|M.smegmatis_MC2_155 TVPVELEDAARVDGTSRLGVLFKIILPLSLPALSTLAALTVLTSWNDFLW
MAB_1716c|M.abscessus_ATCC_199 TIPDDLIRAARLDGANTLDILWHVVVPVSRPILITLTLITVVSQWNNFMW
Mflv_3853|M.gilvum_PYR-GCK QIPWEMEHAAQVDGATQWQAFRKVIVPLAAPGVFTTAILTFFFCWNDFLF
Mvan_2542|M.vanbaalenii_PYR-1 QIPWEMEHAAQVDGATQWQAFRKVIVPLAAPGVFTTAILTFFFCWNDFLF
TH_2867|M.thermoresistible__bu EIPWDLEKAAKMDGATPGQAFRKVIAPLAAPGIVTAAILVFIFAWNDLLL
:* :: ** :** . ::: * : * : . :. . **:::
Rv2039c|M.tuberculosis_H37Rv PLLMIQRNSLATLTLGLVRLRG--EYVARWPVLMAASMLMLVPLVILYAV
Mb2065c|M.bovis_AF2122/97 PLLMIQRNSLATLTLGLVRLRG--EYVARWPVLMAASMLMLVPLVILYAV
MMAR_3012|M.marinum_M PLLMVQRDSIATLTLGLVRMQG--EYVARWPVLMATSMLILLPLVVVYAV
MUL_2253|M.ulcerans_Agy99 PLLMVQRDSIATLTLGLVRMQG--EYVARWPVLMATSMLILLPLVAVYAV
MLBr_01425|M.leprae_Br4923 PLLMIQRNSLATLTLGLVRMRG--EYGTCWPVIMATSMLIILPLVIIYTI
MAV_2478|M.avium_104 PLLMIQRSSLATLTLGLVRMKG--EYVARWPVLMAASMLIMLPLVIIYAI
MSMEG_0517|M.smegmatis_MC2_155 PLIVITSQDQMTVPLGLSYFQG--AHRVKWPLLMAANVMSLLPMLLVFIG
MAB_1716c|M.abscessus_ATCC_199 PLVITSGGNWRVLTVATAGLQS--QFNAQWPIVMAATTVAIVPLVILFVA
Mflv_3853|M.gilvum_PYR-GCK AISLTSTDSARTVPAALAFFQGASYFESPVPYIMAASVIVTIPVVILVLV
Mvan_2542|M.vanbaalenii_PYR-1 AISLTSTDSARTVPAALAFFQGASYFESPVPYIMAASVIVTIPVVILVLI
TH_2867|M.thermoresistible__bu ALSLTATERAITAPVAIANFTGSSQFEEPTGSIAAGAMVITIPIIVFVLI
.: : . . . : . . : * : :*:: .
Rv2039c|M.tuberculosis_H37Rv AQRSFVRGIAVTGLGG
Mb2065c|M.bovis_AF2122/97 AQRSFVRGIAVTGLGG
MMAR_3012|M.marinum_M AQRAFIRGIAVTGLGG
MUL_2253|M.ulcerans_Agy99 AQRAFIRGIAVTGLGG
MLBr_01425|M.leprae_Br4923 AQRAFVRGITVTRIGG
MAV_2478|M.avium_104 AQRSFVRGIAVTGMGG
MSMEG_0517|M.smegmatis_MC2_155 AQRYFVQSVASTGLKG
MAB_1716c|M.abscessus_ATCC_199 FQKYIVRSITLSGLK-
Mflv_3853|M.gilvum_PYR-GCK FQRRIVAGLTSGAVKG
Mvan_2542|M.vanbaalenii_PYR-1 FQRRIVAGLTSGAVKG
TH_2867|M.thermoresistible__bu FQRRIVSGLTSGAVKG
*: :: .:: :