For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. bovis AF2122 / 97 Mb2065c (-)

annotation: sugar-transport integral membrane protein ABC transporter
coordinates: 2268712 - 2269554
length: 280

VGWADRIVHRHFIRGLALYAGLIGIAWCALFPIIWALSGSLKADGEVTEPTLFPSHPQWSNYREVFALMP
FWRMFFNTVLYAGCVTAGQVFFCSLAGYAFARLQFRGRDTLFVLYLSTLMVPLTVTVIPQFILMRIVGWV
DTPWAMIVPGLFGSAFGTYLMRQFFRTLPTDLEEAAILDGCSPWQIYWRILLPHSRPAVLVLGVLTWVNV
WNDFLWPLLMIQRNSLATLTLGLVRLRGEYVARWPVLMAASMLMLVPLVILYAVAQRSFVRGIAVTGLGG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2065c--100% (280)sugar-transport integral membrane protein ABC transporter
M. bovis AF2122 / 97Mb2344uspB6e-4837.69% (268) sugar-transport integral membrane protein ABC transporter
M. bovis AF2122 / 97Mb2858cugpE1e-3932.10% (271) sn-glycerol-3-phosphate transport integral membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3853-2e-3431.20% (266) binding-protein-dependent transport systems inner membrane
M. tuberculosis H37RvRv2039c-1e-16599.64% (280) sugar-transport integral membrane protein ABC transporter
M. leprae Br4923MLBr_01425-1e-13779.51% (283) putative ABC-transport protein, inner membrane component
M. abscessus ATCC 19977MAB_1716c-5e-5340.82% (267) sugar ABC transporter, permease protein
M. marinum MMMAR_3012-1e-14585.71% (280) sugar ABC transporter
M. avium 104MAV_2478-1e-13981.07% (280) sugar ABC transporter, permease
M. smegmatis MC2 155MSMEG_0517-3e-5741.11% (270) sugar binding-protein dependent transporter system permease
M. thermoresistible (build 8)TH_2867-4e-2929.07% (258) PUTATIVE binding-protein-dependent transport systems inner
M. ulcerans Agy99MUL_2253-1e-14384.64% (280) sugar ABC transporter
M. vanbaalenii PYR-1Mvan_2542-5e-3430.45% (266) binding-protein-dependent transport systems inner membrane

CLUSTAL 2.0.9 multiple sequence alignment


Mb2065c|M.bovis_AF2122/97           MGWADR------------------IVHRHFIRG--LALYAGLIGIAWCAL
Rv2039c|M.tuberculosis_H37Rv        MGWADR------------------IVHRHFIRG--LALYAGLIGIAWCAL
MMAR_3012|M.marinum_M               MGSADR------------------VVQRKIVRA--VALYAALIAIAWCAL
MUL_2253|M.ulcerans_Agy99           MGSADR------------------VVQRNIVRA--VALYAALIAIAWCAM
MLBr_01425|M.leprae_Br4923          MGLAERLNH---------------IVKRSVLRA--VVVYIALTGIAWCAL
MAV_2478|M.avium_104                MGSSEA------------------VIKRTVLRA--ATVYAALLGIAWCAL
MSMEG_0517|M.smegmatis_MC2_155      MTTTPHITAPVAESTEPTVVEDFSPRRRTRLRLPFSPWHLVLIPVTFLLI
MAB_1716c|M.abscessus_ATCC_199      MTWSRN-----------------------------VLVYLLLTVGAVLTL
Mflv_3853|M.gilvum_PYR-GCK          ------------------------------MTKNTKWWTIAGIVIVIYSF
Mvan_2542|M.vanbaalenii_PYR-1       ------------------------------MTKNTKWWTIAGIVIVIYSF
TH_2867|M.thermoresistible__bu      -------------------------VNERVTARRATGWIVIDLLVILYAL
                                                                                     :

Mb2065c|M.bovis_AF2122/97           FPIIWALSGSLKADGEVT--EPTLFPSHPQWSNYREVFALM----PFWRM
Rv2039c|M.tuberculosis_H37Rv        FPIIWALSGSLKADGEVT--EPTLFPSHPQWSNYREVFALM----PFWRM
MMAR_3012|M.marinum_M               FPILWALSGSLKKSGEVS--EPRLLPSDPQWSNYAEVFTLM----PFWRM
MUL_2253|M.ulcerans_Agy99           FPILWALSGSLKKGGEVS--EPRLLPSDPQWSNYAEVFTLM----PFWRM
MLBr_01425|M.leprae_Br4923          FPIVWALSGSLKKEGEIR--EPTLLPAHPQWSNYTEVFDLI----PFWRM
MAV_2478|M.avium_104                FPIAWAVSGSLKTEGEVS--EPTLVPARPRWSNYTEVFALM----PIGRM
MSMEG_0517|M.smegmatis_MC2_155      LPLLWMLVTSLQTEGEANRFPPVLLPESPRFENYTEAWATA----PFGHF
MAB_1716c|M.abscessus_ATCC_199      GPFLLAVSASLKTAKQFATGTPLAPPNPFTLANYTG-LADA----GFGRA
Mflv_3853|M.gilvum_PYR-GCK          VPMLWMISLAFKPPSDIVSGEPSFLPSTVTFDNFAQIFS---NPL-FTRA
Mvan_2542|M.vanbaalenii_PYR-1       VPMLWMISLAFKPPSDIVSGKPSFLPSSITFDNFAQIFS---QPL-FTRA
TH_2867|M.thermoresistible__bu      FPVLWILSLSLKSTATVKDGK--LIPDEITFDNYKAIFRGGGSGV-FTSA
                                     *.   :  :::             *      *:            :   

Mb2065c|M.bovis_AF2122/97           FFNTVLYAGCVTAGQVFFCSLAGYAFARLQFRGRDTLFVLYLSTLMVPLT
Rv2039c|M.tuberculosis_H37Rv        FFNTVLYAGCVTAGQVFFCSLAGYAFARLQFRGRDTLFVLYLSTLMVPLT
MMAR_3012|M.marinum_M               FFNTVLYAGCVTAGQIFFCSLAGYAFARLEFRGRDTLFVLYLGTLMVPLT
MUL_2253|M.ulcerans_Agy99           FFNTVLYAGCVTAGQIFFCSLAGYAFARLEFRGRDTLFVLYLGTLMVPLT
MLBr_01425|M.leprae_Br4923          FFNTVLYAGYVTVGQVFFCSLAGYAFARLQFRGRDALFVLYLGTLMMPLT
MAV_2478|M.avium_104                FVNTVLYAGCVTAGHVFFCSLAGYAFARLDFRGRNTLFVVYLGTLMVPLT
MSMEG_0517|M.smegmatis_MC2_155      FLNSFAVTGVVLVSNLVVCSLAGYAFARIRFLGRGALFITLMATLMVPFQ
MAB_1716c|M.abscessus_ATCC_199      ALVTVLMTAIIVIGQLTFSVLAAYAFARLRFPGRDGLFWIYLATLMIPAT
Mflv_3853|M.gilvum_PYR-GCK          LINSIGIALVATVISVIIAMFAAYAIARLEFPGKKVLLSLALGIAMFPQA
Mvan_2542|M.vanbaalenii_PYR-1       LINSIGIAVIATVISVIIAMFAAYAIARLEFPGKKVLLSLALGIAMFPQA
TH_2867|M.thermoresistible__bu      LINSIGIGLITTVIAVVVGGMAAYAVARLNFPGKRLLIGVALLIAMFPQI
                                     . :.          : .  :*.**.**: * *:  *:   :   *.*  

Mb2065c|M.bovis_AF2122/97           VTVIPQFILMRIVG-------WVDTPWAMIVPG-LFGSAFGTYLMRQFFR
Rv2039c|M.tuberculosis_H37Rv        VTVIPQVILMRIVG-------WVDTPWAMIVPG-LFGSAFGTYLMRQFFR
MMAR_3012|M.marinum_M               VTVIPQFILMRTVG-------LVDTPWAMIVPG-LFGSAFGTYLMRQFFR
MUL_2253|M.ulcerans_Agy99           VTVIPHFILMRTVG-------LVDTPWAMIVPG-LFGSAFGTYLMRQFFR
MLBr_01425|M.leprae_Br4923          VTIIPQFILMRVLG-------WTDTPWAMIVPG-LFGSAFGTYLMRQFFR
MAV_2478|M.avium_104                VTVIPQFLIMRTLG-------WVDTPWAMIVPG-FFGSAFGTYLMRQFFR
MSMEG_0517|M.smegmatis_MC2_155      VTMIPVFLIVKWFGDNVWEGLGINHIGALMLP--NLATAFGIFFLRQFFL
MAB_1716c|M.abscessus_ATCC_199      VTVVPMYLMLTQVG-------LRNTFWALVIPF-MFGSPYAIFLLREHFR
Mflv_3853|M.gilvum_PYR-GCK          ALVGPLFDMWRGLG-------IYDTWLGLIIPYLTFALPLSIWTMSAFFR
Mvan_2542|M.vanbaalenii_PYR-1       ALVGPLFDMWRGLG-------IYDTWLGLIIPYLTFALPLSIWTMSAFFR
TH_2867|M.thermoresistible__bu      SLVTPLFNIERQLG-------LFDTWAGLIIPYITFALPLAIYTLSAFFR
                                      : *   :   .*         :   .:::*   :. . . : :  .* 

Mb2065c|M.bovis_AF2122/97           TLPTDLEEAAILDGCSPWQIYWRILLPHSRPAVLVLGVLTWVNVWNDFLW
Rv2039c|M.tuberculosis_H37Rv        TLPTDLEEAAILDGCSPWQIYWRILLPHSRPAVLVLGVLTWVNVWNDFLW
MMAR_3012|M.marinum_M               TLPSDLEEAATLDGCSPWQIYWRILLPHARPAVMVLGVLTWVNVWNDFLW
MUL_2253|M.ulcerans_Agy99           TLPSDLEKAATLDGCSPWQIYWRILLPHARPAVMVLGVLTWVNVWNDFLW
MLBr_01425|M.leprae_Br4923          TLPSDLEEAAILDGCSPWQIYWRVLLPHAKPAVGVLAVLTWVNVWNDFLW
MAV_2478|M.avium_104                TLPTDLEEAAILDGCTPWQVYWRILLPHARPAVMVLAVLTWVNVWNDFLW
MSMEG_0517|M.smegmatis_MC2_155      TVPVELEDAARVDGTSRLGVLFKIILPLSLPALSTLAALTVLTSWNDFLW
MAB_1716c|M.abscessus_ATCC_199      TIPDDLIRAARLDGANTLDILWHVVVPVSRPILITLTLITVVSQWNNFMW
Mflv_3853|M.gilvum_PYR-GCK          QIPWEMEHAAQVDGATQWQAFRKVIVPLAAPGVFTTAILTFFFCWNDFLF
Mvan_2542|M.vanbaalenii_PYR-1       QIPWEMEHAAQVDGATQWQAFRKVIVPLAAPGVFTTAILTFFFCWNDFLF
TH_2867|M.thermoresistible__bu      EIPWDLEKAAKMDGATPGQAFRKVIAPLAAPGIVTAAILVFIFAWNDLLL
                                     :* ::  ** :** .      ::: * : * : .   :. .  **::: 

Mb2065c|M.bovis_AF2122/97           PLLMIQRNSLATLTLGLVRLRG--EYVARWPVLMAASMLMLVPLVILYAV
Rv2039c|M.tuberculosis_H37Rv        PLLMIQRNSLATLTLGLVRLRG--EYVARWPVLMAASMLMLVPLVILYAV
MMAR_3012|M.marinum_M               PLLMVQRDSIATLTLGLVRMQG--EYVARWPVLMATSMLILLPLVVVYAV
MUL_2253|M.ulcerans_Agy99           PLLMVQRDSIATLTLGLVRMQG--EYVARWPVLMATSMLILLPLVAVYAV
MLBr_01425|M.leprae_Br4923          PLLMIQRNSLATLTLGLVRMRG--EYGTCWPVIMATSMLIILPLVIIYTI
MAV_2478|M.avium_104                PLLMIQRSSLATLTLGLVRMKG--EYVARWPVLMAASMLIMLPLVIIYAI
MSMEG_0517|M.smegmatis_MC2_155      PLIVITSQDQMTVPLGLSYFQG--AHRVKWPLLMAANVMSLLPMLLVFIG
MAB_1716c|M.abscessus_ATCC_199      PLVITSGGNWRVLTVATAGLQS--QFNAQWPIVMAATTVAIVPLVILFVA
Mflv_3853|M.gilvum_PYR-GCK          AISLTSTDSARTVPAALAFFQGASYFESPVPYIMAASVIVTIPVVILVLV
Mvan_2542|M.vanbaalenii_PYR-1       AISLTSTDSARTVPAALAFFQGASYFESPVPYIMAASVIVTIPVVILVLI
TH_2867|M.thermoresistible__bu      ALSLTATERAITAPVAIANFTGSSQFEEPTGSIAAGAMVITIPIIVFVLI
                                    .: :       . . .   : .   .      : *   :  :*:: .   

Mb2065c|M.bovis_AF2122/97           AQRSFVRGIAVTGLGG
Rv2039c|M.tuberculosis_H37Rv        AQRSFVRGIAVTGLGG
MMAR_3012|M.marinum_M               AQRAFIRGIAVTGLGG
MUL_2253|M.ulcerans_Agy99           AQRAFIRGIAVTGLGG
MLBr_01425|M.leprae_Br4923          AQRAFVRGITVTRIGG
MAV_2478|M.avium_104                AQRSFVRGIAVTGMGG
MSMEG_0517|M.smegmatis_MC2_155      AQRYFVQSVASTGLKG
MAB_1716c|M.abscessus_ATCC_199      FQKYIVRSITLSGLK-
Mflv_3853|M.gilvum_PYR-GCK          FQRRIVAGLTSGAVKG
Mvan_2542|M.vanbaalenii_PYR-1       FQRRIVAGLTSGAVKG
TH_2867|M.thermoresistible__bu      FQRRIVSGLTSGAVKG
                                     *: :: .::   :