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ALVSTARVDLVCEGGGVRGIGLVGAVDALADAGYRFPRVAGSSAGAIVASLVAALQTAGEPVTRLAEMMR SIDYPKFLDRNLIGHVPLIGGGLSLLLSDGVYRGAYLEQLLGGLLADLGVHTFGDLRTGEAPEQFAWSLV VTASDLSRRRLVRIPWDLDSYGIHPDDFSVARAVHASSAIPFVFEPVRVRGATWVDGGLLSNFPVALFDR TDAEPRWPTFGIRLSARPGIPPTRPVQGPVSLGIAAIETLVSNQDNAYIDDPCTVRRTIFVPAHDVSPID FDITAEQREALYQRGFQAGQKFLANWNYADCLADCGGPFTPSL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2037c | - | - | 100% (324) | POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. tuberculosis H37Rv | Rv3728 | - | 3e-10 | 29.65% (199) | hypothetical protein Rv3728 |
| M. tuberculosis H37Rv | Rv2565 | - | 8e-09 | 27.92% (197) | hypothetical protein Rv2565 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2063c | - | 0.0 | 99.69% (324) | transmembrane protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | MLBr_01423 | - | 1e-152 | 80.50% (323) | hypothetical protein MLBr_01423 |
| M. abscessus ATCC 19977 | MAB_4758 | - | 3e-08 | 28.93% (197) | patatin-like protein |
| M. marinum M | MMAR_3010 | - | 1e-166 | 88.44% (320) | hypothetical protein MMAR_3010 |
| M. avium 104 | MAV_2480 | - | 1e-159 | 87.82% (312) | phospholipase, patatin family protein |
| M. smegmatis MC2 155 | MSMEG_5743 | - | 4e-07 | 28.19% (227) | patatin |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2251 | - | 1e-165 | 87.81% (320) | hypothetical protein MUL_2251 |
| M. vanbaalenii PYR-1 | Mvan_1130 | - | 4e-65 | 44.55% (321) | patatin |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2037c|M.tuberculosis_H37Rv ---MALVSTARVDLVCEGGGVRGIGLVGAVDALADAGYRFPRVAGSSAGA
Mb2063c|M.bovis_AF2122/97 ---MALVSTARVDLVCEGGGVRGIGLVGAVDALADAGYRFPRVAGSSAGA
MMAR_3010|M.marinum_M ------MSAARVDLVCEGGGVRGIGLVGAVDALAEAGYEFPRVAGSSAGA
MUL_2251|M.ulcerans_Agy99 ------MNAARVDLVCEGGGVRGIGLVGAVDALAEAGYEFPRVAGSSVGA
MAV_2480|M.avium_104 ---------MRADLVCEGGGVRGIGLVGAVDALAAAGYRFPRVAGSSAGA
MLBr_01423|M.leprae_Br4923 MLYLVIVSVVHADLVCQGGGIRGIGLVGAVDALATAGYRFPRVAGTSAGA
Mvan_1130|M.vanbaalenii_PYR-1 --MTPKRNPRRADLVLSGGGVKGIGLVGAVGALRDAGYALERISGTSAGS
MAB_4758|M.abscessus_ATCC_1997 ---------MTTAFVLSGGASLGSIQVGMLLALAEAGIAPDLIVGTSVGA
MSMEG_5743|M.smegmatis_MC2_155 -----------MAFVLGGGGVLGAAEAGMALALLESGVRPDLVCGTSVGA
:* **. * .* ** :* : *:*.*:
Rv2037c|M.tuberculosis_H37Rv IVASLVAALQTAG-EPVTRLAEMMRSIDYPKFLDRNLIGHVPLIGGGLSL
Mb2063c|M.bovis_AF2122/97 IVASLVAALQTAG-EPVTRLAEMMRSIDYPKFLDRNLIGHVPLIGGGLSL
MMAR_3010|M.marinum_M IVAAMVAALQTAG-EPLSRLAEIMRTLDYRKFLDRNLIGHIPLIGGGLSL
MUL_2251|M.ulcerans_Agy99 IVAAMVAALQTAG-EPLSRLAEIMRTLDYRKFLDRNLIGHIPLIGGGLSL
MAV_2480|M.avium_104 VVASLVAALQTAG-EPLSRLTDIMRTIDYRKFLDRNLIGHVPVIGGGLSL
MLBr_01423|M.leprae_Br4923 LVASLIAALQTAG-EPLTRLAEVMRTIDYRKFFDRSLIGRVPLIGGGLSL
Mvan_1130|M.vanbaalenii_PYR-1 LVGAVVAAATQAGGISADQLLELAVNVPYRRFRDSGPIERIPLLGTAWGL
MAB_4758|M.abscessus_ATCC_1997 LNGGWISSRPDID--GINGLADLWRSLSRKDVFPTNLSVGFLGFIGQRQS
MSMEG_5743|M.smegmatis_MC2_155 INGAALAADPTPE--GARALVKFWDALGGDGVFGGSLIRRAAEVLRRPTS
: .. ::: * .. : . . .
Rv2037c|M.tuberculosis_H37Rv LLSDGVYRGAYLEQLLGGLLADLGVHTFGDLRTGEA---PEQFAWSLVVT
Mb2063c|M.bovis_AF2122/97 LLSDGVYRGAYLEQLLGGLLADLGVHTFGDLRTGEA---PEQFAWSLVVT
MMAR_3010|M.marinum_M LVSDGVYRGAYLEQLLAGLLADLGVHTFGDLRTGEQ---PEQFAWSLVVT
MUL_2251|M.ulcerans_Agy99 LVSDGVYRGAYLEQLLAGLLADLGVHTFGDLRTGEQ---PEQFAWSLVVT
MAV_2480|M.avium_104 LTSDGVYRGAYLEQLLAGLLGDLGVRTFGDLRTGEA---PEQFAWSLVVT
MLBr_01423|M.leprae_Br4923 LVSDGVYQGAYLEEWLTSLLGDLGVYTFGDLRTGEE---PEQFAWSLVVT
Mvan_1130|M.vanbaalenii_PYR-1 LRGTGIYRGDFAHQWIRGELKNLGVSTFGDLAVDDDNLLPER-RYRLVVT
MAB_4758|M.abscessus_ATCC_1997 LVSDSGLRRLLKEHLLFRRLEDAPIP--------------------LHVV
MSMEG_5743|M.smegmatis_MC2_155 LHDNSELRRLLRERLPVHTFEELAVP--------------------FECV
* . . : .. : : : : .
Rv2037c|M.tuberculosis_H37Rv ASDLSRRRLVRIPWDLD-SYGIHPDDFSVARAVHASSAIPFVFEPVRVRG
Mb2063c|M.bovis_AF2122/97 ASDLSRRRLVRIPWDLD-SYGIHPDDFSVARAVHASSAIPFVFEPVRVRG
MMAR_3010|M.marinum_M ASDLSRRRLVRIPWDLD-SYGLDPDEFSVARAVHASSAIPFVFEPVRVRG
MUL_2251|M.ulcerans_Agy99 ASDLSRRRLVRIPWDLD-SYGLDPDEFSVARAVHASSAIPFVFEPVRVRG
MAV_2480|M.avium_104 ASDLSRRRLVRIPWDLG-SYGIDPDDFPVARAVHASSAIPYVFEPVRVGG
MLBr_01423|M.leprae_Br4923 ASDLSRRRLVRIPWDLD-AYGINPDDFSVARAVHASSAIPYVFEPVQVAG
Mvan_1130|M.vanbaalenii_PYR-1 VADLTTGQLVRLPWDYKRLYGLDPDEQSVADAVRASMSIPFLFRPSTLKD
MAB_4758|M.abscessus_ATCC_1997 ATDVLTGKDVLLSGGDP------------IDAIAASAAVPAVLPPVRIDG
MSMEG_5743|M.smegmatis_MC2_155 AASIERAREHWFDSGDL------------VEPVLASCALPGVLPPVRIGD
.:.: : : . .: ** ::* :: * : .
Rv2037c|M.tuberculosis_H37Rv AT-----WVDGGLLSNFPVALFDRTD-AEPRWPTFGIRLSARPGIPPTR-
Mb2063c|M.bovis_AF2122/97 AT-----WVDGGLLSNFPVALFDRTD-AEPRWPTFGIRLSARPGIPPTR-
MMAR_3010|M.marinum_M AT-----WVDGGLLSNFPVALFDRAD-GEPRWPTFGIRLSARPGIPPTR-
MUL_2251|M.ulcerans_Agy99 AT-----WVDGGLLSNFPVALFDRAD-GEPRWPTFGIRLSARPGIPPTR-
MAV_2480|M.avium_104 AT-----WVDGGLLSDFPVELFDRPD-GQPQWPTFGIRLSARPGIPPTH-
MLBr_01423|M.leprae_Br4923 AT-----WVDGGLLSTFPVELFDRSD-GDARWPTFGIRLSARPGIPPTH-
Mvan_1130|M.vanbaalenii_PYR-1 AAGQRCTLVDGGVLSNFPIDSFDRLDGAEPRWPTFGVTVVPYLPAPTTDQ
MAB_4758|M.abscessus_ATCC_1997 RD-----LMDGGVVNNTPLSHAVALG-ATEIWVLPTGYACALTETPRGA-
MSMEG_5743|M.smegmatis_MC2_155 EH-----FFDGGLVNSIPLDRAVSRG-ADTIWVLHVGRLEEELRVPRFL-
.***::. *: . . * *
Rv2037c|M.tuberculosis_H37Rv -------PVQGPVSLGIAAIETLVSNQDNAYIDDPCTVRRTIFVPAHDVS
Mb2063c|M.bovis_AF2122/97 -------PVQGPVSLGIAAIETLVSNQDNAYIDDPCTVRRTIFVPAHDVS
MMAR_3010|M.marinum_M -------PVHGPVSLGIAAIETLVSNQDNAYIDDPCTVQRTIFVPADGVS
MUL_2251|M.ulcerans_Agy99 -------PVHGPVSLGIAAIETLVSNQDNAYIDDPCTVQRTIFVPADGVS
MAV_2480|M.avium_104 -------PVHGPVSLGIAAIETLVSNQDNAYIDDPCTVRRTIFVPAEDVS
MLBr_01423|M.leprae_Br4923 -------PVRGPVSLGIAAIETLVSNQDNAYIDDSCTMLRTIFVPADEVS
Mvan_1130|M.vanbaalenii_PYR-1 LIPGLRLPWDGPTFL-ESLITTMLVGHDQAHLSQPWVKVRAIQVDSTDVG
MAB_4758|M.abscessus_ATCC_1997 ------------VPMALHAMTLAINQRLVADVNR-FEGSVDLRVVPGLCP
MSMEG_5743|M.smegmatis_MC2_155 ------------WEVGFAAFEIARRHRFHGDLER-VRSDVAVHVLPSGQP
: : : . :. : * .
Rv2037c|M.tuberculosis_H37Rv PIDFDITAEQREALYQRGFQAGQKFLANWNYADCLADCGGPFTPSL--
Mb2063c|M.bovis_AF2122/97 PIDFDITAEQREALYQRGFQAGQKFLANWNYADYLADCGGPFTPSL--
MMAR_3010|M.marinum_M PIDFDITSEQRDALYRRGLQAGRKFLQSWNYADYLTECGSPAAPSP--
MUL_2251|M.ulcerans_Agy99 PIDFDITSEQRDALYRRGLQAGRKFLQSWNYADYLTECGSPAAPSP--
MAV_2480|M.avium_104 PIDFDITAQQREALYERGRQAGQQFLQTWNYADYLKACGGPVPETP--
MLBr_01423|M.leprae_Br4923 PIDFNITVEQRQALYQSGLQAGQQFLKTWNYTEYLTACGRPVTRSAGL
Mvan_1130|M.vanbaalenii_PYR-1 VLDFDITPSEADALYDKGYAAASEFLASWDWPAYLQRFRRTHYVT---
MAB_4758|M.abscessus_ATCC_1997 VRTSPADFSHADELIGRAHEQTRRWLLMPRFKINQADLLEHHHG----
MSMEG_5743|M.smegmatis_MC2_155 QR---AAATWSNLRYRDSRRIGRRAEVAYDATREYLKALP--------
: . .