For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AFVLGGGGVLGAAEAGMALALLESGVRPDLVCGTSVGAINGAALAADPTPEGARALVKFWDALGGDGVFG GSLIRRAAEVLRRPTSLHDNSELRRLLRERLPVHTFEELAVPFECVAASIERAREHWFDSGDLVEPVLAS CALPGVLPPVRIGDEHFFDGGLVNSIPLDRAVSRGADTIWVLHVGRLEEELRVPRFLWEVGFAAFEIARR HRFHGDLERVRSDVAVHVLPSGQPQRAAATWSNLRYRDSRRIGRRAEVAYDATREYLKALP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5743 | - | - | 100% (272) | patatin |
| M. smegmatis MC2 155 | MSMEG_5285 | - | 4e-13 | 32.67% (202) | phospholipase, patatin family protein |
| M. smegmatis MC2 155 | MSMEG_5284 | - | 1e-09 | 27.81% (187) | patatin |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1092c | - | 3e-12 | 26.74% (187) | hypothetical protein Mb1092c |
| M. gilvum PYR-GCK | Mflv_2030 | - | 1e-12 | 29.38% (211) | patatin |
| M. tuberculosis H37Rv | Rv1063c | - | 3e-12 | 26.74% (187) | hypothetical protein Rv1063c |
| M. leprae Br4923 | MLBr_01423 | - | 5e-07 | 26.79% (224) | hypothetical protein MLBr_01423 |
| M. abscessus ATCC 19977 | MAB_4758 | - | 3e-39 | 36.33% (267) | patatin-like protein |
| M. marinum M | MMAR_2150 | - | 1e-37 | 35.42% (271) | alpha-beta hydrolase superfamily esterase |
| M. avium 104 | MAV_1190 | - | 9e-13 | 29.28% (181) | patatin |
| M. thermoresistible (build 8) | TH_1491 | - | 1e-11 | 29.05% (210) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1736 | - | 4e-36 | 35.06% (271) | alpha-beta hydrolase superfamily esterase |
| M. vanbaalenii PYR-1 | Mvan_4687 | - | 9e-12 | 28.96% (183) | patatin |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2150|M.marinum_M -------------------MTTAFVLSGGASLG-AIQVGMLQALADEG--
MUL_1736|M.ulcerans_Agy99 MAAVRNSSDMAGNRPYDASVTTAFVLSGGASLG-AIQVGMLQALADEG--
MAB_4758|M.abscessus_ATCC_1997 -------------------MTTAFVLSGGASLG-SIQVGMLLALAEAG--
MSMEG_5743|M.smegmatis_MC2_155 ---------------------MAFVLGGGGVLG-AAEAGMALALLESG--
Mb1092c|M.bovis_AF2122/97 -----MPAPAALRVRGSSSPRVALALGSGGARG-YAHIGVIQALRERG--
Rv1063c|M.tuberculosis_H37Rv -----MPAPAALRVRGSSSPRVALALGSGGARG-YAHIGVIQALRERG--
MAV_1190|M.avium_104 ---------------------MALALGSGGARG-YAHIGVIEALQARG--
Mflv_2030|M.gilvum_PYR-GCK -------------------MRVALALGSGGARG-YAHIGVLNELRERG--
Mvan_4687|M.vanbaalenii_PYR-1 -------------------MRVALALGSGGARG-YAHIGVLNELTERG--
MLBr_01423|M.leprae_Br4923 ----------MLYLVIVSVVHADLVCQGGGIRG-IGLVGAVDALATAG--
TH_1491|M.thermoresistible__bu -----------------VANRRALVLAGGGLAGIAWETGVLLGIADESPH
:. .*. * * : .
MMAR_2150|M.marinum_M -----ITPDLIIGTSVGALNGGWIASRPDA-AGIRALAGLWRSLTRKEVF
MUL_1736|M.ulcerans_Agy99 -----ITPDLIIGTSVGALNGGWIASRPDA-AGIRALAGLWRSLTRKEVF
MAB_4758|M.abscessus_ATCC_1997 -----IAPDLIVGTSVGALNGGWISSRPDI-DGINGLADLWRSLSRKDVF
MSMEG_5743|M.smegmatis_MC2_155 -----VRPDLVCGTSVGAINGAALAADPTP-EGARALVKFWDALGGDGVF
Mb1092c|M.bovis_AF2122/97 -----YDIVGIAGSSMGAVVGGVHAAG-----RLDEFAHWAKSLTQRTIL
Rv1063c|M.tuberculosis_H37Rv -----YDIVGIAGSSMGAVVGGVHAAG-----RLDEFAHWAKSLTQRTIL
MAV_1190|M.avium_104 -----YDIVGVAGSSMGALVGGLQAAG-----RLDEFAEWAKSLTQRTIL
Mflv_2030|M.gilvum_PYR-GCK -----HEVVGIAGSSMGALVGGLEAAG-----KTDEFTLWATSLTQRAVL
Mvan_4687|M.vanbaalenii_PYR-1 -----HEVVGIAGSSMGALVGGLQAAG-----KLDEYTAWASSLTQRAVL
MLBr_01423|M.leprae_Br4923 -----YRFPRVAGTSAGALVASLIAALQTAGEPLTRLAEVMRTIDYRKFF
TH_1491|M.thermoresistible__bu TADLLLTSDVLVGTSAGSAVAAQLGSGAPLTRLFERQLDPNTAEIKPRVA
: *:* *: .. .: : .
MMAR_2150|M.marinum_M PTQPVTGLMGFLGRRQHLVPN--------TGLRRILSRELEFTNLEDAPI
MUL_1736|M.ulcerans_Agy99 PTQPVTGVMGFLGRRQHLVPN--------TGLRRILSRELEFTNLEDAPI
MAB_4758|M.abscessus_ATCC_1997 PTNLSVGFLGFIGQRQSLVSD--------SGLRRLLKEHLLFRRLEDAPI
MSMEG_5743|M.smegmatis_MC2_155 GGSLIRRAAEVLRRPTSLHDN--------SELRRLLRERLPVHTFEELAV
Mb1092c|M.bovis_AF2122/97 R------LLDPSISAAGILRA--------EKILDAVRDIVGPVAIEQLPI
Rv1063c|M.tuberculosis_H37Rv R------LLDPSISAAGILRA--------EKILDAVRDIVGPVAIEQLPI
MAV_1190|M.avium_104 R------LLDPSISAAGVMRA--------GKILDAVRDILGPVAIEDLRI
Mflv_2030|M.gilvum_PYR-GCK R------LLDPSISSPGVLRA--------EKILESVRDILGEVTIEDLPI
Mvan_4687|M.vanbaalenii_PYR-1 R------LLDPSITSAGVLRA--------EKILDAVRAIVGDVTIEELPI
MLBr_01423|M.leprae_Br4923 DRSLIGRVPLIGGGLSLLVSDGVYQGAYLEEWLTSLLGDLGVYTFGDLRT
TH_1491|M.thermoresistible__bu IDDLTAEFLEAVRRPGSTVEKLRRIG--AVALSTGTVGEAERRAVIAARL
.
MMAR_2150|M.marinum_M P---------LHVVATDVISGTDVLLSSG-----------NAVDAIAASA
MUL_1736|M.ulcerans_Agy99 P---------LHVVATDVISGTDVLLSSG-----------NAVDAIAASA
MAB_4758|M.abscessus_ATCC_1997 P---------LHVVATDVLTGKDVLLSGG-----------DPIDAIAASA
MSMEG_5743|M.smegmatis_MC2_155 P---------FECVAASIERAREHWFDSG-----------DLVEPVLASC
Mb1092c|M.bovis_AF2122/97 P---------YTAVATDLLAGKSVWFQRG-----------PLDAAIRASI
Rv1063c|M.tuberculosis_H37Rv P---------YTAVATDLLAGKSVWFQRG-----------PLDAAIRASI
MAV_1190|M.avium_104 P---------YTAVATDLLAGKSVWFQRG-----------PLDEAIRASI
Mflv_2030|M.gilvum_PYR-GCK P---------YTSVATDLITGKSVWMQRG-----------RVDDAIRASI
Mvan_4687|M.vanbaalenii_PYR-1 P---------YTAVATDLITGKSVWMQRG-----------PLDDAIRASI
MLBr_01423|M.leprae_Br4923 GEEPEQFAWSLVVTASDLSRRRLVRIPWDLDAYGINPDDFSVARAVHASS
TH_1491|M.thermoresistible__bu PAHDWP-DRDLRLSAVDVGTGELVCFDRD--------SGVPLVDAVAASC
* .: : . .: **
MMAR_2150|M.marinum_M AIPGIFPPVSINGRELIDGGVVNNTPVSHAVALGADKIWVLPTGYSC---
MUL_1736|M.ulcerans_Agy99 AIPGIFPPVSINGRELIDGGVVNNTPVSHAVALGADKISVLPTGYSC---
MAB_4758|M.abscessus_ATCC_1997 AVPAVLPPVRIDGRDLMDGGVVNNTPLSHAVALGATEIWVLPTGYAC---
MSMEG_5743|M.smegmatis_MC2_155 ALPGVLPPVRIGDEHFFDGGLVNSIPLDRAVSRGADTIWVLHVGRLE---
Mb1092c|M.bovis_AF2122/97 AIPGVIAPHEVDGRLLADGGILDPLPMAPIAGVNADLTIAVSLNGSE-AG
Rv1063c|M.tuberculosis_H37Rv AIPGVIAPHEVDGRLLADGGILDPLPMAPIAGVNADLTIAVSLNGSE-AG
MAV_1190|M.avium_104 AIPGVIAPHTLDGRLLADGGILDPLPMAPLSAVNADLTIAVNLSGSE-AI
Mflv_2030|M.gilvum_PYR-GCK AIPGLITPHVLGGRLLADGGILDPLPMAPIAAAPADITIAVSLSGEDPAV
Mvan_4687|M.vanbaalenii_PYR-1 AIPGVITPYVLDGRLLADGGILDPLPMAPIAAVAADMTIAVSISGDDPEA
MLBr_01423|M.leprae_Br4923 AIPYVFEPVQVAGATWVDGGLLSTFPVELFDRSDGDARWPTFGIRLS---
TH_1491|M.thermoresistible__bu AVPGVWPPVTIGERRYMDGGVASTVNMALAADCDTVVALVPSRRDTP---
*:* : * : ***: . :
MMAR_2150|M.marinum_M ---------------DLQTLPASAVTMVLHAMTLAVNHRLAVDIERFEQT
MUL_1736|M.ulcerans_Agy99 ---------------DLQTLPASAVTLVLHAMTLAVNHRLAVDIERFEQT
MAB_4758|M.abscessus_ATCC_1997 ---------------ALTETPRGAVPMALHAMTLAINQRLVADVNRFEGS
MSMEG_5743|M.smegmatis_MC2_155 ---------------EELRVPRFLWEVGFAAFEIARRHRFHGDLERVRSD
Mb1092c|M.bovis_AF2122/97 PARDAEP-NVTAEWLNRMVRSTSALFDVSAARSLLDRPTARAVLSRFGAA
Rv1063c|M.tuberculosis_H37Rv PARDAEP-NVTAEWLNRMVRSTSALFDVSAARSLLDRPTARAVLSRFGAA
MAV_1190|M.avium_104 TRREAEP-AATAEWLTRMMRSTSALFDTAAARSLLDRPTARAVLSRLGGP
Mflv_2030|M.gilvum_PYR-GCK DRRMQDLRQPTTDWLSRMWRSSSSLLDTKAARSLLETPTGRAVLGRFVAA
Mvan_4687|M.vanbaalenii_PYR-1 SGRGRESRAPSTDWLNRMWRSSSSLLDTKAARSLLDTPTGRAVLGRFAAG
MLBr_01423|M.leprae_Br4923 ---------------ARPGIPPTHPVRGPVSLGIAAIETLVSNQDNAYID
TH_1491|M.thermoresistible__bu ----------------SPFGPGPAREIDEFGGAAVGVFADDASVAAFGXX
. .
MMAR_2150|M.marinum_M ----------------------------------------VDLRVIRPLC
MUL_1736|M.ulcerans_Agy99 ----------------------------------------VDLRVIRPLC
MAB_4758|M.abscessus_ATCC_1997 ----------------------------------------VDLRVVPGLC
MSMEG_5743|M.smegmatis_MC2_155 ----------------------------------------VAVHVLP---
Mb1092c|M.bovis_AF2122/97 AAESDSWSQAPEIEQRPAGPPADREEAADTPG----LPKMGSFEVMNRTI
Rv1063c|M.tuberculosis_H37Rv AAESDSWSQAPEIEQRPAGPPADREEAADTPG----LPKMGSFEVMNRTI
MAV_1190|M.avium_104 SGDADAWPDNPEEPDQPVLADDD-DEAVELPGAATDVPKLGSFEVMNRTI
Mflv_2030|M.gilvum_PYR-GCK DDEP--------IDAPPEVVKHDSADATGVPE----LPRLGSFEVMNRVI
Mvan_4687|M.vanbaalenii_PYR-1 DDEP--------LPEPDDKVTEEPGNAG--------IPKLGAFEVMNRVI
MLBr_01423|M.leprae_Br4923 DS--------------------------------------CTMLRTIFVP
TH_1491|M.thermoresistible__bu ----------------------------------------XGGHAVRGPV
MMAR_2150|M.marinum_M PVSISGADFSQSATLIPRSHQATREWLATNPARIGQAALLKPHLH-----
MUL_1736|M.ulcerans_Agy99 PVSISGADFSQSATLIPRPHQATREWLATNPARIGQAALLKPHLH-----
MAB_4758|M.abscessus_ATCC_1997 PVRTSPADFSHADELIGRAHEQTRRWLLMPRFKINQADLLEHHHG-----
MSMEG_5743|M.smegmatis_MC2_155 ----SGQPQRAAATWSNLRYRDSRRIGRRAEVAYDATREYLKALP-----
Mb1092c|M.bovis_AF2122/97 DIAQSALARHTLAGYPADLLIEVPRSTCRSLEFHRAVEVIAVGRALATQA
Rv1063c|M.tuberculosis_H37Rv DIAQSALARHTLAGYPADLLIEVPRSTCRSLEFHRAVEVIAVGRALATQA
MAV_1190|M.avium_104 DIAQAALARHTLAVYPPDLLIEVPRSICRGLEFHRAVEVIDAGRALADQA
Mflv_2030|M.gilvum_PYR-GCK DIAQSALARHTLAAYPPDLLIEVPRTVCRSLDFHRAHEVIEIGQELASAA
Mvan_4687|M.vanbaalenii_PYR-1 DIAQAALARHTLAAYPPDLLIEVPRTVCRSLDFHRATEVIEIGQELASAA
MLBr_01423|M.leprae_Br4923 ADEVSPIDFNITVEQRQALYQSGLQAGQQFLKTWNYTEYLTACGRPVTRS
TH_1491|M.thermoresistible__bu VEALVGLGFSAKQAEEATDKVLADDPDASTSTALRSALSMLGRK------
MMAR_2150|M.marinum_M ------------------
MUL_1736|M.ulcerans_Agy99 ------------------
MAB_4758|M.abscessus_ATCC_1997 ------------------
MSMEG_5743|M.smegmatis_MC2_155 ------------------
Mb1092c|M.bovis_AF2122/97 LEAFEIDDDESAAATIEG
Rv1063c|M.tuberculosis_H37Rv LEAFEIDDDESAAATIEG
MAV_1190|M.avium_104 LDALEDGDDDRPAVER--
Mflv_2030|M.gilvum_PYR-GCK LEALDPEPSEA-------
Mvan_4687|M.vanbaalenii_PYR-1 LDTLEQKVPETASDT---
MLBr_01423|M.leprae_Br4923 AGL---------------
TH_1491|M.thermoresistible__bu ------------------