For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTTARRRPKRRGTDARTALRNVPILADIDDEQLERLATTVERRHVPANQWLFHAGEPADSIYIVDSGRFV AVAPEGHVFAEMASGDSIGDLGVIAGAARSAGVRALRDGVVWRIAAETFTDMLEATPLLQSAMLRAMARM LRQSRPAKTARRPRVIGVVSNGDTAAAPMVDAIATSLDSHGRTAVIAPPVETTSAVQEYDELVEAFSETL DRAERSNDWVLVVADRGAGDLWRHYVSAQSDRLVVLVDQRYPPDAVDSLATQRPVHLITCLAEPDPSWWD RLAPVSHHPANSDGFGALARRIAGRSLGLVMAGGGARGLAHFGVYQELTEAGVVIDRFGGTSSGAIASAA FALGMDAGDAIAAAREFIAGSDPLGDYTIPISALTRGGRVDRLVQGFFGNTLIEHLPRGFFSVSADMITG DQIIHRRGSVSGAVRASISIPGLIPPVHNGEQLLVDGGLLNNLPANVMCADTDGEVICVDLRRTFVPSKG FGLLPPIVTPPGLLRRLLTGTDNALPPLQETLLRAFDLAASTANLRELPRVAAIIEPDVSKIGVLNFKQI DAALEAGRMAARAALQAQPDLVR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv2565 | - | - | 100% (583) | hypothetical protein Rv2565 |
M. tuberculosis H37Rv | Rv3239c | - | 3e-76 | 36.06% (574) | transmembrane transport protein |
M. tuberculosis H37Rv | Rv3728 | - | 3e-68 | 33.22% (569) | hypothetical protein Rv3728 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2594 | - | 0.0 | 100.00% (583) | hypothetical protein Mb2594 |
M. gilvum PYR-GCK | Mflv_2030 | - | 6e-21 | 36.57% (175) | patatin |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_4751 | - | 2e-20 | 31.05% (306) | hypothetical protein MAB_4751 |
M. marinum M | MMAR_1306 | - | 1e-79 | 36.35% (575) | transmembrane transport protein |
M. avium 104 | MAV_1190 | - | 1e-16 | 32.96% (179) | patatin |
M. smegmatis MC2 155 | MSMEG_5284 | - | 1e-18 | 37.11% (159) | patatin |
M. thermoresistible (build 8) | TH_0679 | - | 1e-19 | 35.80% (176) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_3590 | - | 2e-73 | 34.91% (593) | transmembrane transport protein |
M. vanbaalenii PYR-1 | Mvan_4687 | - | 3e-20 | 35.20% (179) | patatin |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv -------------------------------------------------- Mb2594|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1306|M.marinum_M MSGVSISSFEKVTSRHSKRPGATPARTHLAGHARKGFANLTHRRQPSSAA MUL_3590|M.ulcerans_Agy99 --------------------------MHLSAPAER--SALTSRRQPSATA MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv -------------------------------------------------- Mb2594|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1306|M.marinum_M VLLVAAFGAFLAFLDSTIVNIAFPDIQKSFPSYDLGSLSWILNAYNIVFA MUL_3590|M.ulcerans_Agy99 VLLVASFGAFLAFLDSTIVNIAFPHIQRSFPSYDISSLSWILNGYNIVFA MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv -------------------------------------------------- Mb2594|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1306|M.marinum_M AFLVAAGRMADLLGRRRTFTFGVVIFTIASGLCAVAGSVEWLVAFRVLQG MUL_3590|M.ulcerans_Agy99 AFLVASGRLADVLGRKRMFVFGVVLFTIASGLCAVAGDVEQLVGFRVLQG MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv -------------------------------------------------- Mb2594|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1306|M.marinum_M IGAAVLVPASLALVVEGFEPARRAHAVGLWGAAAAIASGLGPPIGGMLVD MUL_3590|M.ulcerans_Agy99 IGAAVLVPASLALVVEGFDASHRAHAVGLWGAAAAVASGLGPPVGGMLVE MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv -------------------------------------------------- Mb2594|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1306|M.marinum_M WASWRWVFLVNIPLGVVAVLATSRALVESRAAGRRRKPDLRGATLLAGAL MUL_3590|M.ulcerans_Agy99 ASSWRLVFLVNIPLGIVAVLVAGRVLTESRASGRRRVPDLRGAMLLGVAL MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv -------------------------------------------------- Mb2594|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1306|M.marinum_M GLLTLALVKGPDWGWVSVPTLAVFAASAITLVGFVLSSMAAPVPLVEPAY MUL_3590|M.ulcerans_Agy99 GLMTLGLVKGPEWGWISTATIGSFVASSVALVAFVASSRSHPTPLIDPAF MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv -------------------------------------------------- Mb2594|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1306|M.marinum_M LRSRPFVVGNVLTLVAAAGFYCYVLTHVLYLNYVWGYSLLKAGFAIAPAA MUL_3590|M.ulcerans_Agy99 LRVRSFVAGNLLTLVAAAGFYCYVLTHVLYLNYVWHYSLLKAGFAIAPAA MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv -------------------------------------------------- Mb2594|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1306|M.marinum_M LVAAVVAALLGRVADRHGHRLIVTLGALVWAGSLFWYLQRVGTEPDFLRR MUL_3590|M.ulcerans_Agy99 LIAAVVAAVLGRIADQRGHRLVVMAGAIIWAGSLVWYLQRVGTEPNFLRE MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv -------------------------------------------------- Mb2594|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1306|M.marinum_M WLPGQLLQGIGVGATLPVLSSAALTGVAKGGSYATTSAVVSTTRQLGAVI MUL_3590|M.ulcerans_Agy99 WLPGQLLQGIGVGATLPVLGSAALAGLTKGGSYATASAVVSTTRQLGAVI MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv -------------------------------------------------- Mb2594|M.bovis_AF2122/97 -------------------------------------------------- MMAR_1306|M.marinum_M GVAALVILIGKPEHGAAADALRRGWAMAAICFVVVAIAAVLLGRTNSKPG MUL_3590|M.ulcerans_Agy99 GVALLVILIGKPAPGTGVEALRHGWVLAAVCFAAVAVLAGFLGRTQQGAD MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv ----------MTTARRRPKR-----------RGTDARTALRNVPILADID Mb2594|M.bovis_AF2122/97 ----------MTTARRRPKR-----------RGTDARTALRNVPILADID MMAR_1306|M.marinum_M QELEPEP---AAAARAAPTTTEPAAALIAN-RATDEADLLGNLPLFAGLD MUL_3590|M.ulcerans_Agy99 VAGAPESGVARAPARPQPVTPRPAAAPARPPQTTADGDLLRQLPLFAGLP MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv DEQLERLATTVERRHVPANQWLFHAGEPADSIYIVDSGRFVAVAPEGHVF Mb2594|M.bovis_AF2122/97 DEQLERLATTVERRHVPANQWLFHAGEPADSIYIVDSGRFVAVAPEGHVF MMAR_1306|M.marinum_M AAALAELADRVEEVELQAGSYLFLAGDASDSLYVIRRGRVQVLHGD-IVI MUL_3590|M.ulcerans_Agy99 AATMAELRHHTDEIELQAGSYLFHEVDPSDALYVVRSGRLRVVQRD-LVL MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv AEMASGDSIGDLGVIAGAARSAGVRALRDGVVWRIAAETFTDMLEATPLL Mb2594|M.bovis_AF2122/97 AEMASGDSIGDLGVIAGAARSAGVRALRDGVVWRIAAETFTDMLEATPLL MMAR_1306|M.marinum_M KELGRGEVLGELGLLIDAPRSASVRALRDSRLVRLTKAQFDQIANRG--V MUL_3590|M.ulcerans_Agy99 RELGRGEVVGELGLLIDAPRSASVQAMRDFVLIRLSKAQFNRIADRG--V MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv QSAMLRAMARMLRQSRPAKTARRPRVIGVVSNGDTAAAPMVDAIATSLDS Mb2594|M.bovis_AF2122/97 QSAMLRAMARMLRQSRPAKTARRPRVIGVVSNGDTAAAPMVDAIATSLDS MMAR_1306|M.marinum_M LAALVRVLATRLREAPPPAVHT-TSPGVVVSVVGVGADAPVQSVAAGLLT MUL_3590|M.ulcerans_Agy99 LAALVGTLATRLHTAPPPTVDRPASPEAVIAVIGLGAAVPVRPVALALLN MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv HGRTAVIAPPVETTSAVQEYDELVEAFSETLDRAERSNDWVLVVADRGAG Mb2594|M.bovis_AF2122/97 HGRTAVIAPPVETTSAVQEYDELVEAFSETLDRAERSNDWVLVVADRGAG MMAR_1306|M.marinum_M ALSKQLRVVDPG------------RVDIDGLDRAERGADKVLLHAG-AQD MUL_3590|M.ulcerans_Agy99 ALSARVTAVDPG------------RVDRAGLERAEASADKVVLDAS-AND MSMEG_5284|M.smegmatis_MC2_155 -------------------------------------------------- TH_0679|M.thermoresistible__bu -------------------------------------------------- MAV_1190|M.avium_104 -------------------------------------------------- Mflv_2030|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4687|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4751|M.abscessus_ATCC_1997 -------------------------------------------------- Rv2565|M.tuberculosis_H37Rv DLWRHYVSAQSDRLVVLVDQRYPPDAVDSLATQRPVHLIT---CLAEPDP Mb2594|M.bovis_AF2122/97 DLWRHYVSAQSDRLVVLVDQRYPPDAVDSLATQRPVHLIT---CLAEPDP MMAR_1306|M.marinum_M ADWRDFCLRVADRIVLVTGDPDPGAAALPARAQGADLVLAGPTASREQRR MUL_3590|M.ulcerans_Agy99 TGWRDFCLRAADRIVLVSEGPAPRDTQLPARAVGADLVLIGAPASQEDRS MSMEG_5284|M.smegmatis_MC2_155 --------------------------MTHNESMRVALALGSGSARGYAHI TH_0679|M.thermoresistible__bu ----------------------------------VALALGSGGARGYAHI MAV_1190|M.avium_104 ----------------------------------MALALGSGGARGYAHI Mflv_2030|M.gilvum_PYR-GCK --------------------------------MRVALALGSGGARGYAHI Mvan_4687|M.vanbaalenii_PYR-1 --------------------------------MRVALALGSGGARGYAHI MAB_4751|M.abscessus_ATCC_1997 ---------------------MTGEASTGVPGTKIALALGAGGARGYAHI Rv2565|M.tuberculosis_H37Rv SWWDRLAPVSHHPANS----DGFGALARRIAGRSLGLVMAGGGARGLAHF Mb2594|M.bovis_AF2122/97 SWWDRLAPVSHHPANS----DGFGALARRIAGRSLGLVMAGGGARGLAHF MMAR_1306|M.marinum_M SWEELITPRSVHAVHYRRVVQDLRPLAARLAGRSIGLVLGGGGARGFAHL MUL_3590|M.ulcerans_Agy99 RWEELIPPRSVHSVSYRSLKDDVRPLAARITGGSIGLVLGGGGARAFAHL :.*.:..*.**. **: MSMEG_5284|M.smegmatis_MC2_155 GVINELRARGYEIVGISGSSMGALVGGLYAAGKLDEFAEWACTLTQRAVL TH_0679|M.thermoresistible__bu GVIEELRARGHEVVGVSGSSMGALVGGVMAAGKLDDYAAWARTLTQRSVL MAV_1190|M.avium_104 GVIEALQARGYDIVGVAGSSMGALVGGLQAAGRLDEFAEWAKSLTQRTIL Mflv_2030|M.gilvum_PYR-GCK GVLNELRERGHEVVGIAGSSMGALVGGLEAAGKTDEFTLWATSLTQRAVL Mvan_4687|M.vanbaalenii_PYR-1 GVLNELTERGHEVVGIAGSSMGALVGGLQAAGKLDEYTAWASSLTQRAVL MAB_4751|M.abscessus_ATCC_1997 GVIQELHERGFEISGISGSSMGALVGGLEAAGALDEFALWATSLTQRAVL Rv2565|M.tuberculosis_H37Rv GVYQELTEAGVVIDRFGGTSSGAIASAAFALGMDAGDAIAAAREFIAGSD Mb2594|M.bovis_AF2122/97 GVYQELTEAGVVIDRFGGTSSGAIASAAFALGMDAGDAIAAAREFIAGSD MMAR_1306|M.marinum_M GILEELEQAGVAIDRFAGTSMGAVIASLGASGLDAATADAYAYEYFIRNN MUL_3590|M.ulcerans_Agy99 GVLDELEAAGIVVDRFAGTSMGAVIAALAASGLDAAGVDAHVFEYLVRHN *: : * * : ..*:* **: .. * * . MSMEG_5284|M.smegmatis_MC2_155 RLLDPSLSAAGILRAEKILDAVRDILGDVTIEELPIPYTAVATDLITGKA TH_0679|M.thermoresistible__bu RLLDPSLTAPGVLRAEKILDAVREILGEATIETLPIPFTAVATDLIAGKS MAV_1190|M.avium_104 RLLDPSISAAGVMRAGKILDAVRDILGPVAIEDLRIPYTAVATDLLAGKS Mflv_2030|M.gilvum_PYR-GCK RLLDPSISSPGVLRAEKILESVRDILGEVTIEDLPIPYTSVATDLITGKS Mvan_4687|M.vanbaalenii_PYR-1 RLLDPSITSAGVLRAEKILDAVRAIVGDVTIEELPIPYTAVATDLITGKS MAB_4751|M.abscessus_ATCC_1997 RLLDPTWTSPGFFRAEKILDVVRELLGDVAIEDLPIPFTAVATDLIAGKS Rv2565|M.tuberculosis_H37Rv PLGDYTIPISALTRGGRVDRLVQGFFGNTLIEHLPRGFFSVSADMITGDQ Mb2594|M.bovis_AF2122/97 PLGDYTIPISALTRGGRVDRLVQGFFGNTLIEHLPRGFFSVSADMITGDQ MMAR_1306|M.marinum_M PLRDYAVPIKGLVRGRRTLTLLEAAFGDRLVEELPKEFRCVSVDLIARQP MUL_3590|M.ulcerans_Agy99 PLGDYTLPSKGLVRGRRTMGLLREAYSGRMVEELPKEFRCVSVDLLARQA * * : . .. *. : :. . :* * : .*:.*::: . MSMEG_5284|M.smegmatis_MC2_155 VWLQRGRVDTAIRASIAIPGVIAPHVHDGRLLGDGGILDPLPMAPIASVN TH_0679|M.thermoresistible__bu VWLQRGPVDGAIRASIAIPGVIAPHVLDGRLLADGGILDPVPMAPIAAVN MAV_1190|M.avium_104 VWFQRGPLDEAIRASIAIPGVIAPHTLDGRLLADGGILDPLPMAPLSAVN Mflv_2030|M.gilvum_PYR-GCK VWMQRGRVDDAIRASIAIPGLITPHVLGGRLLADGGILDPLPMAPIAAAP Mvan_4687|M.vanbaalenii_PYR-1 VWMQRGPLDDAIRASIAIPGVITPYVLDGRLLADGGILDPLPMAPIAAVA MAB_4751|M.abscessus_ATCC_1997 VWLQNGSLASAIRASIAIPGMISPHVLNGRVLADGGVLDLPAVAPLAGVH Rv2565|M.tuberculosis_H37Rv IIHRRGSVSGAVRASISIPGLIPPVHNGEQLLVDGGLLNNLPANVMCADT Mb2594|M.bovis_AF2122/97 IIHRRGSVSGAVRASISIPGLIPPVHNGEQLLVDGGLLNNLPANVMCADT MMAR_1306|M.marinum_M VVHRRGRLVDVVGCSLRLPGIYPPQVYQGRLHVDGGVLDNLPVSTLATS- MUL_3590|M.ulcerans_Agy99 VVHRRGPVAEVVGCSLRVPGLYPPQIYNGQLHVDGGVLNNLPVTALTRA- : :.* : .: .*: :**: .* :: ***:*: . : MSMEG_5284|M.smegmatis_MC2_155 ADLTIAVSVSGSETPPETASEAHSEPAE-GGGTKPTTEWLNRMMRSTSAV TH_0679|M.thermoresistible__bu ADVTIAVSLAGSEAG-------GAEPADRGAGARPTAEWVN---RLTAAL MAV_1190|M.avium_104 ADLTIAVNLSGSEAITRR----EAEPAA-------TAEWLTRMMRSTSAL Mflv_2030|M.gilvum_PYR-GCK ADITIAVSLSGEDPAVDR----RMQDLR-----QPTTDWLSRMWRSSSSL Mvan_4687|M.vanbaalenii_PYR-1 ADMTIAVSISGDDPEASG----RGRESR-----APSTDWLNRMWRSSSSL MAB_4751|M.abscessus_ATCC_1997 AELRVAVTLSGGDERRAP---APPEPEPEPREPRVTTEWLNRLLRSTSAL Rv2565|M.tuberculosis_H37Rv DGEVICVDLRRTFVPSKG---FGLLPPI---------------------- Mb2594|M.bovis_AF2122/97 DGEVICVDLRRTFVPSKG---FGLLPPI---------------------- MMAR_1306|M.marinum_M DGPLIAVSLASGEVP-------GAPLQP---------------------- MUL_3590|M.ulcerans_Agy99 EGPMIAVSVGFGGNPS------GGQPRR---------------------- :.* : MSMEG_5284|M.smegmatis_MC2_155 LDTAAVRSVLDRPTSRAVLSRFGVSVTESD----------DGTDASEDAT TH_0679|M.thermoresistible__bu LDSAAARTVRDR---------FGSGAAPADP---------DPVDQDRELE MAV_1190|M.avium_104 FDTAAARSLLDRPTARAVLSRLGGPSGDADAWPDNPEEPDQPVLADDDDE Mflv_2030|M.gilvum_PYR-GCK LDTKAARSLLETPTGRAVLGRFVAA---DD----------EPIDAPPEVV Mvan_4687|M.vanbaalenii_PYR-1 LDTKAARSLLDTPTGRAVLGRFAAG---DD----------EPLPEPDDKV MAB_4751|M.abscessus_ATCC_1997 FST-------------------------------------------DDPE Rv2565|M.tuberculosis_H37Rv ---------------------------------------------VTPPG Mb2594|M.bovis_AF2122/97 ---------------------------------------------VTPPG MMAR_1306|M.marinum_M ---------------------------------------------DGPP- MUL_3590|M.ulcerans_Agy99 ---------------------------------------------SGPI- MSMEG_5284|M.smegmatis_MC2_155 VPESSAEP--AGVPRLGSFEVMYRTIDIAQAALARHTLAAYPPDLLIEVP TH_0679|M.thermoresistible__bu EAAENSRS--ITVPRLGSFEVMNRTIDIAQAALARHTLAAYPPDVVIEIP MAV_1190|M.avium_104 AVELPGAA--TDVPKLGSFEVMNRTIDIAQAALARHTLAVYPPDLLIEVP Mflv_2030|M.gilvum_PYR-GCK KHDSADATGVPELPRLGSFEVMNRVIDIAQSALARHTLAAYPPDLLIEVP Mvan_4687|M.vanbaalenii_PYR-1 TEEPGNAG----IPKLGAFEVMNRVIDIAQAALARHTLAAYPPDLLIEVP MAB_4751|M.abscessus_ATCC_1997 VAGQPDPA-----AKLTSFEVMNRTIEVMQSQLARMQLAAHPPDVLIEVP Rv2565|M.tuberculosis_H37Rv LLRRLLTGTDNALPPLQ--ETLLRAFDLAASTANLRELPRVA--AIIEPD Mb2594|M.bovis_AF2122/97 LLRRLLTGTDNALPPLQ--ETLLRAFDLAASTANLRELPRVA--AIIEPD MMAR_1306|M.marinum_M -----------RVPGIG--DTLIRTMTIGSQRGADVALGLAQ--VVIRPD MUL_3590|M.ulcerans_Agy99 -----------QVPGIG--DTLMRTMMMGSRTVADAAQAEAL--VVIRPD . : :.: *.: : :*. MSMEG_5284|M.smegmatis_MC2_155 RTVCRSLEFNRAAEVIETGRRLAAEALDS--------------------- TH_0679|M.thermoresistible__bu RSVCRSLDFHRAAEVIDAGRELAAAALDDAGLT----------------- MAV_1190|M.avium_104 RSICRGLEFHRAVEVIDAGRALADQALDALEDGDDDRPAVER-------- Mflv_2030|M.gilvum_PYR-GCK RTVCRSLDFHRAHEVIEIGQELASAALEALDPEPSEA------------- Mvan_4687|M.vanbaalenii_PYR-1 RTVCRSLDFHRATEVIEIGQELASAALDTLEQKVPETASDT--------- MAB_4751|M.abscessus_ATCC_1997 RSVSRSLDFHRATEVIEVGRRCAAEALDAYAHTN---------------- Rv2565|M.tuberculosis_H37Rv VSKIGVLNFKQIDAALEAGRMAARAALQAQPDLVR--------------- Mb2594|M.bovis_AF2122/97 VSKIGVLNFKQIDAALEAGRMAARAALQAQPDLVR--------------- MMAR_1306|M.marinum_M TSAVGLLEFHQIDAAREAGRAAARESMPQIMALLNQ-------------- MUL_3590|M.ulcerans_Agy99 TRAVGLLEFHQIDAAREAGRAAARAALPQIIPLLRSGPAGQTTGRAIDRS *:*:: . : *: * :: MSMEG_5284|M.smegmatis_MC2_155 ------------ TH_0679|M.thermoresistible__bu ------------ MAV_1190|M.avium_104 ------------ Mflv_2030|M.gilvum_PYR-GCK ------------ Mvan_4687|M.vanbaalenii_PYR-1 ------------ MAB_4751|M.abscessus_ATCC_1997 ------------ Rv2565|M.tuberculosis_H37Rv ------------ Mb2594|M.bovis_AF2122/97 ------------ MMAR_1306|M.marinum_M --------RR-- MUL_3590|M.ulcerans_Agy99 ARALRTDARRPA