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M. tuberculosis H37Rv Rv2565 (-)

annotation: hypothetical protein Rv2565
coordinates: 2884611 - 2886362
length: 583

MTTARRRPKRRGTDARTALRNVPILADIDDEQLERLATTVERRHVPANQWLFHAGEPADSIYIVDSGRFV
AVAPEGHVFAEMASGDSIGDLGVIAGAARSAGVRALRDGVVWRIAAETFTDMLEATPLLQSAMLRAMARM
LRQSRPAKTARRPRVIGVVSNGDTAAAPMVDAIATSLDSHGRTAVIAPPVETTSAVQEYDELVEAFSETL
DRAERSNDWVLVVADRGAGDLWRHYVSAQSDRLVVLVDQRYPPDAVDSLATQRPVHLITCLAEPDPSWWD
RLAPVSHHPANSDGFGALARRIAGRSLGLVMAGGGARGLAHFGVYQELTEAGVVIDRFGGTSSGAIASAA
FALGMDAGDAIAAAREFIAGSDPLGDYTIPISALTRGGRVDRLVQGFFGNTLIEHLPRGFFSVSADMITG
DQIIHRRGSVSGAVRASISIPGLIPPVHNGEQLLVDGGLLNNLPANVMCADTDGEVICVDLRRTFVPSKG
FGLLPPIVTPPGLLRRLLTGTDNALPPLQETLLRAFDLAASTANLRELPRVAAIIEPDVSKIGVLNFKQI
DAALEAGRMAARAALQAQPDLVR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2565--100% (583)hypothetical protein Rv2565
M. tuberculosis H37RvRv3239c-3e-7636.06% (574) transmembrane transport protein
M. tuberculosis H37RvRv3728-3e-6833.22% (569) hypothetical protein Rv3728

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2594-0.0100.00% (583) hypothetical protein Mb2594
M. gilvum PYR-GCKMflv_2030-6e-2136.57% (175) patatin
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4751-2e-2031.05% (306) hypothetical protein MAB_4751
M. marinum MMMAR_1306-1e-7936.35% (575) transmembrane transport protein
M. avium 104MAV_1190-1e-1632.96% (179) patatin
M. smegmatis MC2 155MSMEG_5284-1e-1837.11% (159) patatin
M. thermoresistible (build 8)TH_0679-1e-1935.80% (176) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_3590-2e-7334.91% (593) transmembrane transport protein
M. vanbaalenii PYR-1Mvan_4687-3e-2035.20% (179) patatin

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2594|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1306|M.marinum_M               MSGVSISSFEKVTSRHSKRPGATPARTHLAGHARKGFANLTHRRQPSSAA
MUL_3590|M.ulcerans_Agy99           --------------------------MHLSAPAER--SALTSRRQPSATA
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2594|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1306|M.marinum_M               VLLVAAFGAFLAFLDSTIVNIAFPDIQKSFPSYDLGSLSWILNAYNIVFA
MUL_3590|M.ulcerans_Agy99           VLLVASFGAFLAFLDSTIVNIAFPHIQRSFPSYDISSLSWILNGYNIVFA
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2594|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1306|M.marinum_M               AFLVAAGRMADLLGRRRTFTFGVVIFTIASGLCAVAGSVEWLVAFRVLQG
MUL_3590|M.ulcerans_Agy99           AFLVASGRLADVLGRKRMFVFGVVLFTIASGLCAVAGDVEQLVGFRVLQG
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2594|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1306|M.marinum_M               IGAAVLVPASLALVVEGFEPARRAHAVGLWGAAAAIASGLGPPIGGMLVD
MUL_3590|M.ulcerans_Agy99           IGAAVLVPASLALVVEGFDASHRAHAVGLWGAAAAVASGLGPPVGGMLVE
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2594|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1306|M.marinum_M               WASWRWVFLVNIPLGVVAVLATSRALVESRAAGRRRKPDLRGATLLAGAL
MUL_3590|M.ulcerans_Agy99           ASSWRLVFLVNIPLGIVAVLVAGRVLTESRASGRRRVPDLRGAMLLGVAL
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2594|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1306|M.marinum_M               GLLTLALVKGPDWGWVSVPTLAVFAASAITLVGFVLSSMAAPVPLVEPAY
MUL_3590|M.ulcerans_Agy99           GLMTLGLVKGPEWGWISTATIGSFVASSVALVAFVASSRSHPTPLIDPAF
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2594|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1306|M.marinum_M               LRSRPFVVGNVLTLVAAAGFYCYVLTHVLYLNYVWGYSLLKAGFAIAPAA
MUL_3590|M.ulcerans_Agy99           LRVRSFVAGNLLTLVAAAGFYCYVLTHVLYLNYVWHYSLLKAGFAIAPAA
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2594|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1306|M.marinum_M               LVAAVVAALLGRVADRHGHRLIVTLGALVWAGSLFWYLQRVGTEPDFLRR
MUL_3590|M.ulcerans_Agy99           LIAAVVAAVLGRIADQRGHRLVVMAGAIIWAGSLVWYLQRVGTEPNFLRE
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2594|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1306|M.marinum_M               WLPGQLLQGIGVGATLPVLSSAALTGVAKGGSYATTSAVVSTTRQLGAVI
MUL_3590|M.ulcerans_Agy99           WLPGQLLQGIGVGATLPVLGSAALAGLTKGGSYATASAVVSTTRQLGAVI
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2594|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1306|M.marinum_M               GVAALVILIGKPEHGAAADALRRGWAMAAICFVVVAIAAVLLGRTNSKPG
MUL_3590|M.ulcerans_Agy99           GVALLVILIGKPAPGTGVEALRHGWVLAAVCFAAVAVLAGFLGRTQQGAD
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         ----------MTTARRRPKR-----------RGTDARTALRNVPILADID
Mb2594|M.bovis_AF2122/97            ----------MTTARRRPKR-----------RGTDARTALRNVPILADID
MMAR_1306|M.marinum_M               QELEPEP---AAAARAAPTTTEPAAALIAN-RATDEADLLGNLPLFAGLD
MUL_3590|M.ulcerans_Agy99           VAGAPESGVARAPARPQPVTPRPAAAPARPPQTTADGDLLRQLPLFAGLP
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         DEQLERLATTVERRHVPANQWLFHAGEPADSIYIVDSGRFVAVAPEGHVF
Mb2594|M.bovis_AF2122/97            DEQLERLATTVERRHVPANQWLFHAGEPADSIYIVDSGRFVAVAPEGHVF
MMAR_1306|M.marinum_M               AAALAELADRVEEVELQAGSYLFLAGDASDSLYVIRRGRVQVLHGD-IVI
MUL_3590|M.ulcerans_Agy99           AATMAELRHHTDEIELQAGSYLFHEVDPSDALYVVRSGRLRVVQRD-LVL
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         AEMASGDSIGDLGVIAGAARSAGVRALRDGVVWRIAAETFTDMLEATPLL
Mb2594|M.bovis_AF2122/97            AEMASGDSIGDLGVIAGAARSAGVRALRDGVVWRIAAETFTDMLEATPLL
MMAR_1306|M.marinum_M               KELGRGEVLGELGLLIDAPRSASVRALRDSRLVRLTKAQFDQIANRG--V
MUL_3590|M.ulcerans_Agy99           RELGRGEVVGELGLLIDAPRSASVQAMRDFVLIRLSKAQFNRIADRG--V
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         QSAMLRAMARMLRQSRPAKTARRPRVIGVVSNGDTAAAPMVDAIATSLDS
Mb2594|M.bovis_AF2122/97            QSAMLRAMARMLRQSRPAKTARRPRVIGVVSNGDTAAAPMVDAIATSLDS
MMAR_1306|M.marinum_M               LAALVRVLATRLREAPPPAVHT-TSPGVVVSVVGVGADAPVQSVAAGLLT
MUL_3590|M.ulcerans_Agy99           LAALVGTLATRLHTAPPPTVDRPASPEAVIAVIGLGAAVPVRPVALALLN
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         HGRTAVIAPPVETTSAVQEYDELVEAFSETLDRAERSNDWVLVVADRGAG
Mb2594|M.bovis_AF2122/97            HGRTAVIAPPVETTSAVQEYDELVEAFSETLDRAERSNDWVLVVADRGAG
MMAR_1306|M.marinum_M               ALSKQLRVVDPG------------RVDIDGLDRAERGADKVLLHAG-AQD
MUL_3590|M.ulcerans_Agy99           ALSARVTAVDPG------------RVDRAGLERAEASADKVVLDAS-AND
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------------------------------
TH_0679|M.thermoresistible__bu      --------------------------------------------------
MAV_1190|M.avium_104                --------------------------------------------------
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4751|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2565|M.tuberculosis_H37Rv         DLWRHYVSAQSDRLVVLVDQRYPPDAVDSLATQRPVHLIT---CLAEPDP
Mb2594|M.bovis_AF2122/97            DLWRHYVSAQSDRLVVLVDQRYPPDAVDSLATQRPVHLIT---CLAEPDP
MMAR_1306|M.marinum_M               ADWRDFCLRVADRIVLVTGDPDPGAAALPARAQGADLVLAGPTASREQRR
MUL_3590|M.ulcerans_Agy99           TGWRDFCLRAADRIVLVSEGPAPRDTQLPARAVGADLVLIGAPASQEDRS
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      --------------------------MTHNESMRVALALGSGSARGYAHI
TH_0679|M.thermoresistible__bu      ----------------------------------VALALGSGGARGYAHI
MAV_1190|M.avium_104                ----------------------------------MALALGSGGARGYAHI
Mflv_2030|M.gilvum_PYR-GCK          --------------------------------MRVALALGSGGARGYAHI
Mvan_4687|M.vanbaalenii_PYR-1       --------------------------------MRVALALGSGGARGYAHI
MAB_4751|M.abscessus_ATCC_1997      ---------------------MTGEASTGVPGTKIALALGAGGARGYAHI
Rv2565|M.tuberculosis_H37Rv         SWWDRLAPVSHHPANS----DGFGALARRIAGRSLGLVMAGGGARGLAHF
Mb2594|M.bovis_AF2122/97            SWWDRLAPVSHHPANS----DGFGALARRIAGRSLGLVMAGGGARGLAHF
MMAR_1306|M.marinum_M               SWEELITPRSVHAVHYRRVVQDLRPLAARLAGRSIGLVLGGGGARGFAHL
MUL_3590|M.ulcerans_Agy99           RWEELIPPRSVHSVSYRSLKDDVRPLAARITGGSIGLVLGGGGARAFAHL
                                                                      :.*.:..*.**. **:

MSMEG_5284|M.smegmatis_MC2_155      GVINELRARGYEIVGISGSSMGALVGGLYAAGKLDEFAEWACTLTQRAVL
TH_0679|M.thermoresistible__bu      GVIEELRARGHEVVGVSGSSMGALVGGVMAAGKLDDYAAWARTLTQRSVL
MAV_1190|M.avium_104                GVIEALQARGYDIVGVAGSSMGALVGGLQAAGRLDEFAEWAKSLTQRTIL
Mflv_2030|M.gilvum_PYR-GCK          GVLNELRERGHEVVGIAGSSMGALVGGLEAAGKTDEFTLWATSLTQRAVL
Mvan_4687|M.vanbaalenii_PYR-1       GVLNELTERGHEVVGIAGSSMGALVGGLQAAGKLDEYTAWASSLTQRAVL
MAB_4751|M.abscessus_ATCC_1997      GVIQELHERGFEISGISGSSMGALVGGLEAAGALDEFALWATSLTQRAVL
Rv2565|M.tuberculosis_H37Rv         GVYQELTEAGVVIDRFGGTSSGAIASAAFALGMDAGDAIAAAREFIAGSD
Mb2594|M.bovis_AF2122/97            GVYQELTEAGVVIDRFGGTSSGAIASAAFALGMDAGDAIAAAREFIAGSD
MMAR_1306|M.marinum_M               GILEELEQAGVAIDRFAGTSMGAVIASLGASGLDAATADAYAYEYFIRNN
MUL_3590|M.ulcerans_Agy99           GVLDELEAAGIVVDRFAGTSMGAVIAALAASGLDAAGVDAHVFEYLVRHN
                                    *: : *   *  :  ..*:* **: ..  * *     .            

MSMEG_5284|M.smegmatis_MC2_155      RLLDPSLSAAGILRAEKILDAVRDILGDVTIEELPIPYTAVATDLITGKA
TH_0679|M.thermoresistible__bu      RLLDPSLTAPGVLRAEKILDAVREILGEATIETLPIPFTAVATDLIAGKS
MAV_1190|M.avium_104                RLLDPSISAAGVMRAGKILDAVRDILGPVAIEDLRIPYTAVATDLLAGKS
Mflv_2030|M.gilvum_PYR-GCK          RLLDPSISSPGVLRAEKILESVRDILGEVTIEDLPIPYTSVATDLITGKS
Mvan_4687|M.vanbaalenii_PYR-1       RLLDPSITSAGVLRAEKILDAVRAIVGDVTIEELPIPYTAVATDLITGKS
MAB_4751|M.abscessus_ATCC_1997      RLLDPTWTSPGFFRAEKILDVVRELLGDVAIEDLPIPFTAVATDLIAGKS
Rv2565|M.tuberculosis_H37Rv         PLGDYTIPISALTRGGRVDRLVQGFFGNTLIEHLPRGFFSVSADMITGDQ
Mb2594|M.bovis_AF2122/97            PLGDYTIPISALTRGGRVDRLVQGFFGNTLIEHLPRGFFSVSADMITGDQ
MMAR_1306|M.marinum_M               PLRDYAVPIKGLVRGRRTLTLLEAAFGDRLVEELPKEFRCVSVDLIARQP
MUL_3590|M.ulcerans_Agy99           PLGDYTLPSKGLVRGRRTMGLLREAYSGRMVEELPKEFRCVSVDLLARQA
                                     * * : .  .. *. :    :.   .   :* *   : .*:.*::: . 

MSMEG_5284|M.smegmatis_MC2_155      VWLQRGRVDTAIRASIAIPGVIAPHVHDGRLLGDGGILDPLPMAPIASVN
TH_0679|M.thermoresistible__bu      VWLQRGPVDGAIRASIAIPGVIAPHVLDGRLLADGGILDPVPMAPIAAVN
MAV_1190|M.avium_104                VWFQRGPLDEAIRASIAIPGVIAPHTLDGRLLADGGILDPLPMAPLSAVN
Mflv_2030|M.gilvum_PYR-GCK          VWMQRGRVDDAIRASIAIPGLITPHVLGGRLLADGGILDPLPMAPIAAAP
Mvan_4687|M.vanbaalenii_PYR-1       VWMQRGPLDDAIRASIAIPGVITPYVLDGRLLADGGILDPLPMAPIAAVA
MAB_4751|M.abscessus_ATCC_1997      VWLQNGSLASAIRASIAIPGMISPHVLNGRVLADGGVLDLPAVAPLAGVH
Rv2565|M.tuberculosis_H37Rv         IIHRRGSVSGAVRASISIPGLIPPVHNGEQLLVDGGLLNNLPANVMCADT
Mb2594|M.bovis_AF2122/97            IIHRRGSVSGAVRASISIPGLIPPVHNGEQLLVDGGLLNNLPANVMCADT
MMAR_1306|M.marinum_M               VVHRRGRLVDVVGCSLRLPGIYPPQVYQGRLHVDGGVLDNLPVSTLATS-
MUL_3590|M.ulcerans_Agy99           VVHRRGPVAEVVGCSLRVPGLYPPQIYNGQLHVDGGVLNNLPVTALTRA-
                                    :  :.* :  .: .*: :**: .*     ::  ***:*:  .   :    

MSMEG_5284|M.smegmatis_MC2_155      ADLTIAVSVSGSETPPETASEAHSEPAE-GGGTKPTTEWLNRMMRSTSAV
TH_0679|M.thermoresistible__bu      ADVTIAVSLAGSEAG-------GAEPADRGAGARPTAEWVN---RLTAAL
MAV_1190|M.avium_104                ADLTIAVNLSGSEAITRR----EAEPAA-------TAEWLTRMMRSTSAL
Mflv_2030|M.gilvum_PYR-GCK          ADITIAVSLSGEDPAVDR----RMQDLR-----QPTTDWLSRMWRSSSSL
Mvan_4687|M.vanbaalenii_PYR-1       ADMTIAVSISGDDPEASG----RGRESR-----APSTDWLNRMWRSSSSL
MAB_4751|M.abscessus_ATCC_1997      AELRVAVTLSGGDERRAP---APPEPEPEPREPRVTTEWLNRLLRSTSAL
Rv2565|M.tuberculosis_H37Rv         DGEVICVDLRRTFVPSKG---FGLLPPI----------------------
Mb2594|M.bovis_AF2122/97            DGEVICVDLRRTFVPSKG---FGLLPPI----------------------
MMAR_1306|M.marinum_M               DGPLIAVSLASGEVP-------GAPLQP----------------------
MUL_3590|M.ulcerans_Agy99           EGPMIAVSVGFGGNPS------GGQPRR----------------------
                                        :.* :                                         

MSMEG_5284|M.smegmatis_MC2_155      LDTAAVRSVLDRPTSRAVLSRFGVSVTESD----------DGTDASEDAT
TH_0679|M.thermoresistible__bu      LDSAAARTVRDR---------FGSGAAPADP---------DPVDQDRELE
MAV_1190|M.avium_104                FDTAAARSLLDRPTARAVLSRLGGPSGDADAWPDNPEEPDQPVLADDDDE
Mflv_2030|M.gilvum_PYR-GCK          LDTKAARSLLETPTGRAVLGRFVAA---DD----------EPIDAPPEVV
Mvan_4687|M.vanbaalenii_PYR-1       LDTKAARSLLDTPTGRAVLGRFAAG---DD----------EPLPEPDDKV
MAB_4751|M.abscessus_ATCC_1997      FST-------------------------------------------DDPE
Rv2565|M.tuberculosis_H37Rv         ---------------------------------------------VTPPG
Mb2594|M.bovis_AF2122/97            ---------------------------------------------VTPPG
MMAR_1306|M.marinum_M               ---------------------------------------------DGPP-
MUL_3590|M.ulcerans_Agy99           ---------------------------------------------SGPI-
                                                                                      

MSMEG_5284|M.smegmatis_MC2_155      VPESSAEP--AGVPRLGSFEVMYRTIDIAQAALARHTLAAYPPDLLIEVP
TH_0679|M.thermoresistible__bu      EAAENSRS--ITVPRLGSFEVMNRTIDIAQAALARHTLAAYPPDVVIEIP
MAV_1190|M.avium_104                AVELPGAA--TDVPKLGSFEVMNRTIDIAQAALARHTLAVYPPDLLIEVP
Mflv_2030|M.gilvum_PYR-GCK          KHDSADATGVPELPRLGSFEVMNRVIDIAQSALARHTLAAYPPDLLIEVP
Mvan_4687|M.vanbaalenii_PYR-1       TEEPGNAG----IPKLGAFEVMNRVIDIAQAALARHTLAAYPPDLLIEVP
MAB_4751|M.abscessus_ATCC_1997      VAGQPDPA-----AKLTSFEVMNRTIEVMQSQLARMQLAAHPPDVLIEVP
Rv2565|M.tuberculosis_H37Rv         LLRRLLTGTDNALPPLQ--ETLLRAFDLAASTANLRELPRVA--AIIEPD
Mb2594|M.bovis_AF2122/97            LLRRLLTGTDNALPPLQ--ETLLRAFDLAASTANLRELPRVA--AIIEPD
MMAR_1306|M.marinum_M               -----------RVPGIG--DTLIRTMTIGSQRGADVALGLAQ--VVIRPD
MUL_3590|M.ulcerans_Agy99           -----------QVPGIG--DTLMRTMMMGSRTVADAAQAEAL--VVIRPD
                                                 . :   :.: *.: :                 :*.  

MSMEG_5284|M.smegmatis_MC2_155      RTVCRSLEFNRAAEVIETGRRLAAEALDS---------------------
TH_0679|M.thermoresistible__bu      RSVCRSLDFHRAAEVIDAGRELAAAALDDAGLT-----------------
MAV_1190|M.avium_104                RSICRGLEFHRAVEVIDAGRALADQALDALEDGDDDRPAVER--------
Mflv_2030|M.gilvum_PYR-GCK          RTVCRSLDFHRAHEVIEIGQELASAALEALDPEPSEA-------------
Mvan_4687|M.vanbaalenii_PYR-1       RTVCRSLDFHRATEVIEIGQELASAALDTLEQKVPETASDT---------
MAB_4751|M.abscessus_ATCC_1997      RSVSRSLDFHRATEVIEVGRRCAAEALDAYAHTN----------------
Rv2565|M.tuberculosis_H37Rv         VSKIGVLNFKQIDAALEAGRMAARAALQAQPDLVR---------------
Mb2594|M.bovis_AF2122/97            VSKIGVLNFKQIDAALEAGRMAARAALQAQPDLVR---------------
MMAR_1306|M.marinum_M               TSAVGLLEFHQIDAAREAGRAAARESMPQIMALLNQ--------------
MUL_3590|M.ulcerans_Agy99           TRAVGLLEFHQIDAAREAGRAAARAALPQIIPLLRSGPAGQTTGRAIDRS
                                          *:*::   . : *:  *  ::                       

MSMEG_5284|M.smegmatis_MC2_155      ------------
TH_0679|M.thermoresistible__bu      ------------
MAV_1190|M.avium_104                ------------
Mflv_2030|M.gilvum_PYR-GCK          ------------
Mvan_4687|M.vanbaalenii_PYR-1       ------------
MAB_4751|M.abscessus_ATCC_1997      ------------
Rv2565|M.tuberculosis_H37Rv         ------------
Mb2594|M.bovis_AF2122/97            ------------
MMAR_1306|M.marinum_M               --------RR--
MUL_3590|M.ulcerans_Agy99           ARALRTDARRPA