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MSAQQTNLGIVVGVDGSPCSHTAVEWAARDAQMRNVALRVVQVVPPVITAPEGWAFEYSRFQEAQKREIV EHSYLVAQAHQIVEQAHKVALEASSSGRAAQITGEVLHGQIVPTLANISRQVAMVVLGYRGQGAVAGALL GSVSSSLVRHAHGPVAVIPEEPRPARPPHAPVVVGIDGSPTSGLAAEIAFDEASRRGVDLVALHAWSDMG PLDFPRLNWAPIEWRNLEDEQEKMLARRLSGWQDRYPDVVVHKVVVCDRPAPRLLELAQTAQLVVVGSHG RGGFPGMHLGSVSRAVVNSGQAPVIVARIPQDPAVPA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv1996 | - | - | 100% (317) | hypothetical protein Rv1996 |
M. tuberculosis H37Rv | Rv2005c | - | 9e-72 | 50.16% (315) | hypothetical protein Rv2005c |
M. tuberculosis H37Rv | Rv2026c | - | 1e-70 | 47.42% (310) | hypothetical protein Rv2026c |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2019 | - | 0.0 | 100.00% (317) | hypothetical protein Mb2019 |
M. gilvum PYR-GCK | Mflv_4382 | - | 8e-73 | 51.13% (311) | UspA domain-containing protein |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2489 | - | 1e-46 | 38.06% (310) | hypothetical protein MAB_2489 |
M. marinum M | MMAR_5410 | - | 1e-110 | 63.61% (316) | hypothetical protein MMAR_5410 |
M. avium 104 | MAV_2507 | - | 6e-75 | 50.65% (310) | universal stress protein family protein |
M. smegmatis MC2 155 | MSMEG_3940 | - | 1e-63 | 46.23% (305) | universal stress protein family protein |
M. thermoresistible (build 8) | TH_2494 | - | 3e-63 | 47.59% (311) | PUTATIVE putative conserved hypothetical membrane protein |
M. ulcerans Agy99 | MUL_5033 | - | 1e-109 | 63.29% (316) | hypothetical protein MUL_5033 |
M. vanbaalenii PYR-1 | Mvan_1963 | - | 1e-69 | 49.51% (309) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4382|M.gilvum_PYR-GCK --MSTQPAPLGIVVGVDGSAASRVAVDWAARDAALRQVPLTLAYVLPGAA Mvan_1963|M.vanbaalenii_PYR-1 --MSTQPAPVGIVVAVDGSDASRVAVDWAARDAAMRRIPLTLAHVLPSAA Rv1996|M.tuberculosis_H37Rv --MSAQQTNLGIVVGVDGSPCSHTAVEWAARDAQMRNVALRVVQVVPPVI Mb2019|M.bovis_AF2122/97 --MSAQQTNLGIVVGVDGSPCSHTAVEWAARDAQMRNVALRVVQVVPPVI MMAR_5410|M.marinum_M --MSTESTSPAIVVGVDGSPASTLAVEWAARDAEMRNVPLKVVHVFAPMV MUL_5033|M.ulcerans_Agy99 --MSTESTSPAIVVGVDGSPASTLAVDWAARDAEMRNVPLKVVHVFAPMV MSMEG_3940|M.smegmatis_MC2_155 MSHNGNGAGYGMVVAVDGSAESDAAVRWAAREATLRKIPVTVMHVVEPMI TH_2494|M.thermoresistible__bu --VSSTAAYEGIVVGVDGSAASADAVRWAARSAALRNLQLTLVHVMTATS MAV_2507|M.avium_104 --MAASSKRCGVLVGVDGSPASNFAVCWAARDAAMRNVPLTLVHMVNAAT MAB_2489|M.abscessus_ATCC_1997 --MTTSTPNSHILVGVDGSTSALHALTWAGAEAQRRNLPLTLVHVIDHSS ::*.**** : *: **. .* *.: : : :. Mflv_4382|M.gilvum_PYR-GCK VQS---WIQVPLPASFYEDEK--------AEATRVLADARAVVDAATQAH Mvan_1963|M.vanbaalenii_PYR-1 TQS---WIQVPLPAAFFEDEK--------LEAERILADARALVTAATEGG Rv1996|M.tuberculosis_H37Rv TAPEG-WAFEYSRFQEAQKREIVEHSYLVAQAHQIVEQAHKVALEASSSG Mb2019|M.bovis_AF2122/97 TAPEG-WAFEYSRFQEAQKREIVEHSYLVAQAHQIVEQAHKVALEASSSG MMAR_5410|M.marinum_M TPANG-WADVAMPADYARWRE--------DQAHQIVQQAHAVAVDAAAPG MUL_5033|M.ulcerans_Agy99 APANG-WADVAMPADYARWRE--------DQAHQIVQQAHAVAVDAAAPG MSMEG_3940|M.smegmatis_MC2_155 VN----WPVPPVQGSVTEWQE--------ANARNVIKH----AHDTFVAV TH_2494|M.thermoresistible__bu IGAPLVWPAGPIPDSLIQWQE--------DEARQILADSAEIAENAFQEA MAV_2507|M.avium_104 V-----WPQVPMAAEAVAWQE--------DDGRRVLQEAVKIAEDATRNG MAB_2489|M.abscessus_ATCC_1997 LGQG---YNLGASASFFQHLE--------TDGAEFLSQAKDHVYALHPNV : :. ..: . . Mflv_4382|M.gilvum_PYR-GCK PLPAVT----------EKVLSGQPVPTLADLSRDADMIVVGSRGMGKWER Mvan_1963|M.vanbaalenii_PYR-1 EALTVD----------EVVLSGQPVAALVDLAKDAEMLVMGSRGLGKWER Rv1996|M.tuberculosis_H37Rv RAAQIT----------GEVLHGQIVPTLANISRQVAMVVLGYRGQGAVAG Mb2019|M.bovis_AF2122/97 RAAQIT----------GEVLHGQIVPTLANISRQVAMVVLGYRGQGAVAG MMAR_5410|M.marinum_M RAAHVT----------SEVRYAAIVPAMVELSQQAEMVVVGCRGQGGVAS MUL_5033|M.ulcerans_Agy99 RAAHVT----------SEVRYAAIVPAMVELSLQAEMVVVGCRGQGGVAS MSMEG_3940|M.smegmatis_MC2_155 EESAP-----DGIR--HEIRYAGIVAELVDVSKNATMMVVGSRGLGAFGG TH_2494|M.thermoresistible__bu RAAGPGPAGDDAVRVVTGVVRAAPVPTLVDASKQAKLVAVGSRGQGPLRR MAV_2507|M.avium_104 RNLAIT----------TELWHAPPAPTLAQLSEEAELVVVGSTGRGAIGR MAB_2489|M.abscessus_ATCC_1997 EVSTVK-------------ATGRPVPVLVELSRNALMTVLGSSGLGGFTG . .. :.: : :. : .:* * * Mflv_4382|M.gilvum_PYR-GCK RVLGSVSSGLVHHARCPVAVIYDEDPLIPHPAQAPVVVGIDGSPASERAT Mvan_1963|M.vanbaalenii_PYR-1 RLLGSVSSGVVHHAHCPVAVIHDVDPLIPHPAQAPVVVGVDGSPASEHAT Rv1996|M.tuberculosis_H37Rv ALLGSVSSSLVRHAHGPVAVIPE-EPRPARPPHAPVVVGIDGSPTSGLAA Mb2019|M.bovis_AF2122/97 ALLGSVSSSLVRHAHGPVAVIPE-EPRPARPPHAPVVVGIDGSPTSGLAA MMAR_5410|M.marinum_M ALLGSVSSGLAHHAHCPVAIIHDDEALPPRSAQAPVLVGVDGSPTSELAT MUL_5033|M.ulcerans_Agy99 ALLGSVSSGLAHHAHCPVAIIHDDEPLPPRSAQAPVLVGVDGSPTSELAT MSMEG_3940|M.smegmatis_MC2_155 ALLGSVSSGVIHHAHCPVAVIHGDQIRRPD-PRSPVLVGIDGSPASEDAT TH_2494|M.thermoresistible__bu VLLGSVSSGLVHHAHCPVAVIREGTPHTPDFAKRPVLVGIDGSESAQRAT MAV_2507|M.avium_104 LLLGSVSSGLVRRARCPVAVIHDEDPMMPYPQRAPVLVGIDGSPASELAT MAB_2489|M.abscessus_ATCC_1997 MMAGSVSVSLTAKGHSPVVVVRE----SPVPGGGPVVVGIDDSESSDGAA : **** .: :.: **.:: . **:**:*.* :: *: Mflv_4382|M.gilvum_PYR-GCK AIAFDEACRRGVDLVAVHTWSDAG--YELP-----GVEWTEVQPEEEMLL Mvan_1963|M.vanbaalenii_PYR-1 AIAFDEASFRGVDLVAVHTWSDAG--YELP-----GTGWAEIQPEEDMLL Rv1996|M.tuberculosis_H37Rv EIAFDEASRRGVDLVALHAWSDMGP-LDFPRLNWAPIEWRNLEDEQEKML Mb2019|M.bovis_AF2122/97 EIAFDEASRRGVDLVALHAWSDMGP-LDFPRLNWAPIEWRNLEDEQEKML MMAR_5410|M.marinum_M EIAFDEASRRGAELVALHAWTDMGP-LDFPSINWAPIEWSNIKDQEEEVL MUL_5033|M.ulcerans_Agy99 EIGFDEASRRGAELVALHAWTDMGP-LDFPSINWAPIEWSNIKDQEEEVL MSMEG_3940|M.smegmatis_MC2_155 AFAFDEASRRRVDLIALHAWSDVGV-FSAL-----GMDWHEYEDQGRELL TH_2494|M.thermoresistible__bu AVAFEEASFRGVDLIALHAWSDADI-ADIP-----TLELSAVQQSAERVL MAV_2507|M.avium_104 AIAFDEALRRGVDLNAVHAWSDTQV-FGLP-----GMDWPAVRSQAERSL MAB_2489|M.abscessus_ATCC_1997 AWAFEEAAMRETELVAVHVWNNIPPGYVYAYTAWSAMDSAGEQQRQEQLL .*:** * .:* *:*.*.: . * Mflv_4382|M.gilvum_PYR-GCK SERLAGWHERYPDVTVHRVVRRDQPARRLLEEAEKAQLLVVGSHGRGGFT Mvan_1963|M.vanbaalenii_PYR-1 AERLAGWQERYPDVTVHRVVCRDQPARRLLEEAAKGQLLVVGSHGRGGFG Rv1996|M.tuberculosis_H37Rv ARRLSGWQDRYPDVVVHKVVVCDRPAPRLLELAQTAQLVVVGSHGRGGFP Mb2019|M.bovis_AF2122/97 ARRLSGWQDRYPDVVVHKVVVCDRPAPRLLELAQTAQLVVVGSHGRGGFP MMAR_5410|M.marinum_M AERLCGWQERYPDVVTHKVVVSDRPAPRLLEHAHDAQLVVVGSHGRGGFP MUL_5033|M.ulcerans_Agy99 AERLCGWQERYPDVVTHKVVVSDRPAPRLLEHAHDAQLVVVGSHGRGGFP MSMEG_3940|M.smegmatis_MC2_155 GERLAGWRERYPDVRVTRQIVCDQPARWLIDGSRHAQLVVVGSHGRAGFA TH_2494|M.thermoresistible__bu SERLAGFRERYPDVSVHRRIVGSEPARHLVEASEDAQLVVVGSRGRGGFT MAV_2507|M.avium_104 AERLAGWQERYPDVTVHRMVVCDRPARQLIEQSESAQLTVVGSHGRGGLA MAB_2489|M.abscessus_ATCC_1997 AERLAGWQEKYPDVPVRRVVAVGHPADVLLSQAAGAQLIVTGSRGRGDIA ..**.*::::**** . : : ..** *:. : .** *.**:**..: Mflv_4382|M.gilvum_PYR-GCK GMLLGSVGSQIVQSSRTPVIVARTA------- Mvan_1963|M.vanbaalenii_PYR-1 GMLLGSVGSQVVQSARGPVIVARR-------- Rv1996|M.tuberculosis_H37Rv GMHLGSVSRAVVNSGQAPVIVARIPQDPAVPA Mb2019|M.bovis_AF2122/97 GMHLGSVSRAVVNSGQAPVIVARIPQDPAVPA MMAR_5410|M.marinum_M GMLLGSVSRAVINSARIPVIIARTPPNS---- MUL_5033|M.ulcerans_Agy99 GMLLGSVSRAVVNSARIPVIIARTPANS---- MSMEG_3940|M.smegmatis_MC2_155 GMLLGSVGSKVARAAYSPVIVVR--------- TH_2494|M.thermoresistible__bu GMLLGSVSRAVVNAVTTPVIVAR--------- MAV_2507|M.avium_104 GTLLGSVSNAVVHSVRMPVIVARPS------- MAB_2489|M.abscessus_ATCC_1997 GFFLGSTSHALIHKASCPVLVAPRT------- * ***.. : . **::.