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GRLEGKVAFITGVARGQGRSHAVRLADGQARALGKVDVEACGALVGEVEVWGRDVRDDRRVFVESPADEF GACRRVARQGIRVVGLPVSQRELVEPEAGCAARRSAAGSQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1990A | - | - | 100% (111) | POSSIBLE DEHYDROGENASE (FRAGMENT) |
| M. tuberculosis H37Rv | Rv2750 | - | 2e-07 | 44.87% (78) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv0687 | fabG | 2e-07 | 41.49% (94) | 3-ketoacyl-(acyl-carrier-protein) reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2013c | - | 2e-59 | 100.00% (111) | dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1589 | - | 2e-09 | 54.00% (50) | short-chain dehydrogenase/reductase SDR |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3081 | - | 2e-07 | 58.97% (39) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4754 | - | 2e-08 | 36.08% (97) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_3550 | - | 8e-09 | 74.29% (35) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4801 | - | 3e-09 | 36.61% (112) | carveol dehydrogenase |
| M. thermoresistible (build 8) | TH_4131 | - | 6e-10 | 43.14% (102) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3392 | fabG | 1e-06 | 34.48% (116) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_5168 | - | 2e-09 | 54.00% (50) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4801|M.smegmatis_MC2_155 -MGSAEGRVAGKVAFITGAARGQGRSHAVRLAEEGADIIAVDLCQDIDS-
TH_4131|M.thermoresistible__bu -----VGRVEGKVAFITGAARGQGRSHAVRLAEEGADIIAVDICADIET-
Mflv_1589|M.gilvum_PYR-GCK ----MGGRVEGKVAFITGAARGQGRSHAVRLAEEGADIIAIDVCGPISTH
Mvan_5168|M.vanbaalenii_PYR-1 ----MGGRVEGKVAFITGAARGQGRSHAVRLAEEGADIIAIDVCGPISTH
MMAR_4754|M.marinum_M MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPIVEN
MAB_3081|M.abscessus_ATCC_1997 -----MGKLDGKVAFITGAARGQGRAHAIKLASEGASIIAVDICAQIPS-
MUL_3392|M.ulcerans_Agy99 MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQIAS-
MAV_3550|M.avium_104 -----MGSLDGKVAFITGAARGQGRSHAVRLAREGANIIGIDICADIAA-
Rv1990A|M.tuberculosis_H37Rv -----MGRLEGKVAFITGVARGQGRSHAVRLADGQARALG----------
Mb2013c|M.bovis_AF2122/97 -----MGRLEGKVAFITGVARGQGRSHAVRLADGQARALG----------
* : *:******.******:**::** * :.
MSMEG_4801|M.smegmatis_MC2_155 IGYSLATPEDLEETARYVEKAGRRIVTAQADVRDAAQLKEALERGVSELG
TH_4131|M.thermoresistible__bu IGYSMAKPEDLEETAKLVEKTGRGVYTAQADVRNADQLRTALEGGLKEFG
Mflv_1589|M.gilvum_PYR-GCK TDIPPATPDDLAQTVDLVKGTGRRIVSEQVDVRDFAAVKAAVDSGVEQLG
Mvan_5168|M.vanbaalenii_PYR-1 TDIPAATPDDLAQTVDLVKGIGRRVVAAEVDVRDYAAVKAAVDSGVEQLG
MMAR_4754|M.marinum_M TTIPASTPEDLAETADLVKGHNRRIFTAEADVRDYDALKAAVDAGVDELG
MAB_3081|M.abscessus_ATCC_1997 VEYPMATTEDLDLTVKEVDALGRAISAHETDVRDREALQAAFDAGVHDLG
MUL_3392|M.ulcerans_Agy99 VPYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAALQAGIDELG
MAV_3550|M.avium_104 NGYPMASRAELDQTVALVEEAGGKMLGTVADVRDFGQVKAALDAGVEQFG
Rv1990A|M.tuberculosis_H37Rv ----KVDVEACGALVGEVEVWGR-------DVRD--DRRVFVESPADEFG
Mb2013c|M.bovis_AF2122/97 ----KVDVEACGALVGEVEVWGR-------DVRD--DRRVFVESPADEFG
. *. . ***: .: ::*
MSMEG_4801|M.smegmatis_MC2_155 KLDIVVAQAGIAAMKG-----NPPLQAWTDGINTNLVGTINAIQVALPHL
TH_4131|M.thermoresistible__bu KVDIVVAQAGVAGMKG-----QPPLQAWTDVMNTNLVGTMNAIQVALPHL
Mflv_1589|M.gilvum_PYR-GCK RLDIVVANAGIGNGGQ--TLDHTSEEDWNDMIDVNLSGVWKSVKAAVPHL
Mvan_5168|M.vanbaalenii_PYR-1 RLDIVVANAGIGNGGQ--TLDHTSEEDWNDMIDVNLSGVWKSVKAAVPHL
MMAR_4754|M.marinum_M RLDIIVANAGIGNGGA--TLDKTSEHDWQEMIDVNLSGVWKSVKAAVPHL
MAB_3081|M.abscessus_ATCC_1997 PVDIVVANAGIATLTP-----ECGDDGWRDVLDVNLTGVYHTIEVARPSM
MUL_3392|M.ulcerans_Agy99 QVDIVVANAGIAPMQ-------SGDDGWRDVIDVNLSGAYYTVEVAIPTM
MAV_3550|M.avium_104 RLDIVLANAGIAPLAFRQLSIEEELAQWRAVTGVNLDGAYHTAWAAIPHL
Rv1990A|M.tuberculosis_H37Rv ACRRVARQG------------------------------IRVVGLPVSQR
Mb2013c|M.bovis_AF2122/97 ACRRVARQG------------------------------IRVVGLPVSQR
: :. . .
MSMEG_4801|M.smegmatis_MC2_155 SEG---ASIVATASAAALMDAHNKPNPGADPGGMGYMVSKRMISEYVHYL
TH_4131|M.thermoresistible__bu KEG---ASIIATASAAALMDAHQKPNPGADPGGMAYMSSKRLLAQYVHDL
Mflv_1589|M.gilvum_PYR-GCK LAGGNGGSIILTSSVGGLKPYP-----HTG----HYIAAKHGVIGLMRTF
Mvan_5168|M.vanbaalenii_PYR-1 LSGGRGGSIILTSSVGGLKPYA-----HTG----HYIAAKHGVIGLMRTF
MMAR_4754|M.marinum_M IAGGNGGSIVLTSSVGGMKAYP-----HCG----NYVAAKHGVVGLMRSF
MAB_3081|M.abscessus_ATCC_1997 VQRGAGGSIVLTSSVAGLTGMV-----MDNPGGLAYTAAKHGLVGLMRSY
MUL_3392|M.ulcerans_Agy99 IEQGRGGSIVLISSAAGLVGIS-----SADAGAIGYVASKHALVGLMRVY
MAV_3550|M.avium_104 LAGNRGGVIIFTSSTAGIKGFG-----GLQGGGLGYAASKHGIVGLMRTL
Rv1990A|M.tuberculosis_H37Rv ELVEPEAGCAARRSAAGSQ-------------------------------
Mb2013c|M.bovis_AF2122/97 ELVEPEAGCAARRSAAGSQ-------------------------------
. *...
MSMEG_4801|M.smegmatis_MC2_155 ATELTPLGIRANVIHPTNCNTDMLQSEPMYRSFRPDLEHPTRADAEPVFY
TH_4131|M.thermoresistible__bu ATELAVRGIRANVIHPTNCNTDMLQSEPMYRSFRPDLENPTRADAEPVFG
Mflv_1589|M.gilvum_PYR-GCK AVELGQHSIRVNAVCPTNVNTPLFMNEGTMKLFRPDLENPGPDDLAVAAQ
Mvan_5168|M.vanbaalenii_PYR-1 AVELGQHSIRVNAVCPTNVNTPLFMNEGTMKLFRPDLENPGPDDLAVAAQ
MMAR_4754|M.marinum_M AVELGQHMIRVNSVHPTHVRTPMLHNEGTFKMFRPDLENPGPDDMAPICQ
MAB_3081|M.abscessus_ATCC_1997 ANMLAPHNIRVNTIHPSGVATPMLINPVTEKLFADGSPEGMS-------D
MUL_3392|M.ulcerans_Agy99 ANLLAPHSIRVNSLHPSGVDPPMINNEFIRHWLADLVAETGSG-----PG
MAV_3550|M.avium_104 ANALAPLNIRVNTVHPTAVNTMMATNDDMTEFLQK---NPGAG-----PH
Rv1990A|M.tuberculosis_H37Rv --------------------------------------------------
Mb2013c|M.bovis_AF2122/97 --------------------------------------------------
MSMEG_4801|M.smegmatis_MC2_155 VQQAMKVPWVEPSDISNAVLWLASDESRFVTGMQLRVDAGGYLKWYDYHV
TH_4131|M.thermoresistible__bu VQQAMRVPYVEPEDISNAVLWLASEEARYVTGMQLRVDAGGYLKWYDYHV
Mflv_1589|M.gilvum_PYR-GCK FMHVLPVGWVEPRDISNAVLFLASDEARYVTGLPVTVDAGSMLK------
Mvan_5168|M.vanbaalenii_PYR-1 FMHVLPVGWVEPVDISNAVLFLASDEARYITGLPVTVDAGSMLK------
MMAR_4754|M.marinum_M LFHTLPIPWVEAEDISNAVLFLASDESRYITGVTLPVDAGGCLK------
MAB_3081|M.abscessus_ATCC_1997 TGNALPVVLMEPEDMANTVAWLVSEDARYITGVALPVDAGFTNRR-----
MUL_3392|M.ulcerans_Agy99 AGNALPVQILQADDIAGALAWLVSDEARYITGVALPVDAGCVNKR-----
MAV_3550|M.avium_104 LQNPMPVGMLEPEDVSAAIAYLVSDEARYVTGVTFPVDAGFCNKV-----
Rv1990A|M.tuberculosis_H37Rv --------------------------------------------------
Mb2013c|M.bovis_AF2122/97 --------------------------------------------------