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MTAAKALVSEWNRMGSQMRFFVGTLAGIPDALMHYRGELLRVIAQMGLGTGVLAVIGGTVAIVGFLAMTT GAIVAVQGYNQFASVGVEALTGFASAFFNTREIQPGTVMVALAATVGAGTTAALGAMRINEEIDALEVIG IRSISYLASTRVLAGVVVAVPLFCVGLMTAYLAARVGTTAIYGQGSGVYDHYFNTFLRPTDVLWSSVEVV VVALMIMLVCTYYGYAAHGGPAGVGEAVGRAVRASMVVASIAILVMTLAIYGQSPNFHLAT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1965 | yrbE3B | - | 100% (271) | CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE3B |
| M. tuberculosis H37Rv | Rv0168 | yrbE1B | 5e-78 | 54.33% (254) | integral membrane protein YRBE1B |
| M. tuberculosis H37Rv | Rv0588 | yrbE2B | 2e-77 | 54.09% (257) | integral membrane protein YrbE2b |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0174 | yrbE1B | 5e-78 | 54.33% (254) | integral membrane protein YRBE1B |
| M. gilvum PYR-GCK | Mflv_2100 | - | 2e-99 | 64.66% (266) | hypothetical protein Mflv_2100 |
| M. leprae Br4923 | MLBr_02588 | yrbE1B | 4e-78 | 53.12% (256) | hypothetical protein MLBr_02588 |
| M. abscessus ATCC 19977 | MAB_4154c | - | 3e-77 | 50.00% (266) | hypothetical protein MAB_4154c |
| M. marinum M | MMAR_2881 | yrbE3B | 1e-137 | 91.42% (268) | integral membrane protein, YrbE3B |
| M. avium 104 | MAV_2060 | - | 9e-90 | 58.71% (264) | TrnB2 protein |
| M. smegmatis MC2 155 | MSMEG_0345 | - | 1e-104 | 69.62% (260) | hypothetical protein MSMEG_0345 |
| M. thermoresistible (build 8) | TH_4199 | - | 1e-108 | 71.21% (264) | PUTATIVE protein of unknown function DUF140 |
| M. ulcerans Agy99 | MUL_2871 | yrb3B | 1e-117 | 92.17% (230) | integral membrane protein, Yrb3B |
| M. vanbaalenii PYR-1 | Mvan_0362 | - | 1e-112 | 72.76% (268) | hypothetical protein Mvan_0362 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2881|M.marinum_M -----MTVSASRSSRHRLRRTAKSLVREWNRLGSQMRFYVTTLTGIPDAV
MUL_2871|M.ulcerans_Agy99 --------------------------------------------------
Rv1965|M.tuberculosis_H37Rv ------------------MTAAKALVSEWNRMGSQMRFFVGTLAGIPDAL
MSMEG_0345|M.smegmatis_MC2_155 ----------MSNRLDRVR-------AAWDGIGVQTQFYARAIGSIGDAA
TH_4199|M.thermoresistible__bu -MAGVVTVGGPSRPLPRLRNVWGGLVRAWNRIGRQTEFYWRTVVAVPDAL
Mvan_0362|M.vanbaalenii_PYR-1 -----MTQSAPSRPHPRWYRAAHEVAAGWNELGDQARFYAGTLRAVPDAV
Mflv_2100|M.gilvum_PYR-GCK -----MTVSRPHSQFPWLKARFRSIADPWNQVGVQTKFYGRTLRSIVIAV
MAV_2060|M.avium_104 -------MTEIAREPSRFAALGPRLVESTRKLGEQTVFYGQSLTAIADAI
MAB_4154c|M.abscessus_ATCC_199 ---MSGPYLSTHTVTSYTVRYMRGLGRSFDKFGEQALFYAQSLSYIPAAL
Mb0174|M.bovis_AF2122/97 MSTAAVLRARFPRAVANLRQYGGAAARGLDEAGQLTWFALTSIGQIAHAL
MLBr_02588|M.leprae_Br4923 MSTAAVLRARFPRAAANLNRYGGAAARGIDDIGQMSWFGLIALGNIPNAL
MMAR_2881|M.marinum_M MHYRSELLRVIAQMGFGAGTLAVIGGTVVIVGFLAMTTGAIVAVQGYNQF
MUL_2871|M.ulcerans_Agy99 ---------MIAQMGFGAGTLAVIGGTVVIVGFLGMTTGAIVAVQGYNQF
Rv1965|M.tuberculosis_H37Rv MHYRGELLRVIAQMGLGTGVLAVIGGTVAIVGFLAMTTGAIVAVQGYNQF
MSMEG_0345|M.smegmatis_MC2_155 MNYRTELIRLIATMGLGAGALAVVGGTVAIVGFLTMTTGALVAVQGYNQF
TH_4199|M.thermoresistible__bu MHYRAELIRLIAGMGLGTGALAIVGGTVAIVGFLTITTGGLVAVQGYNQL
Mvan_0362|M.vanbaalenii_PYR-1 RRYPGELLRLIAQMGLGTGALAVVGGTVAIVGFLTITTGALVAVQGYNQF
Mflv_2100|M.gilvum_PYR-GCK TRYRIELVRQIAQMGLGAGALIVIGGTVAIVGFLTVTTGALVAVQGYTDF
MAV_2060|M.avium_104 RRYPGELLRLIAEMGMGTGALAVIGGTVGIIGFLTLTTGALVAVQGYDTL
MAB_4154c|M.abscessus_ATCC_199 TKYRKETIRVLAEITMGTGALVMIGGTVGVAVFLTLASGGVIAVQGYSSL
Mb0174|M.bovis_AF2122/97 RYYRKETLRLIAQIGMGTGAMAVVGGTVAIVGFVTLSGSSLVAIQGFASL
MLBr_02588|M.leprae_Br4923 SRYRKETLRLIAQIGMGTGAMAVVGGTAAIVGFVTLSGSSLVAIQGFASL
:* : :*:*.: ::***. : *: :: ..::*:**: :
MMAR_2881|M.marinum_M ASVGVEALTGFASAFFNTREIQPGTVMVALAATVGAGATAQLGAMRINEE
MUL_2871|M.ulcerans_Agy99 ASVGVEALTGFASAFFNAREIQPGTVMVALAATVGAGATAQLGAMRINEE
Rv1965|M.tuberculosis_H37Rv ASVGVEALTGFASAFFNTREIQPGTVMVALAATVGAGTTAALGAMRINEE
MSMEG_0345|M.smegmatis_MC2_155 ASVGVEALTGFASAFFNVRLIAPGTTAVALSATIGAGATAQLGAMRINEE
TH_4199|M.thermoresistible__bu ASVGFEALTGFASAFFNVRLIVPGTTAVALSATIGAGATAQIGAMRINEE
Mvan_0362|M.vanbaalenii_PYR-1 ASVGVEALTGFASAFFNVRLIVPGTTAVALSATIGAGATAQLGAMRINEE
Mflv_2100|M.gilvum_PYR-GCK SEIGVEALTGFASAFFNVRLIAPATTAVALAATIGAGATAQLGAMRINEE
MAV_2060|M.avium_104 SNIGVEALTGFLSAFLNVRMIAPCTAGLALAATIGAGATAQLGAMRINEE
MAB_4154c|M.abscessus_ATCC_199 GNIGIEALTGFLSAFLNVRIVAPVVAGIAMAATIGAGTTAQLGAMRVAEE
Mb0174|M.bovis_AF2122/97 GNIGVEAFTGFFAALINVRIAGPVVTGVALAATVGAGATAELGAMRISEE
MLBr_02588|M.leprae_Br4923 GAIGVEAFTGFFAALINVRIAAPVITGIVMAATVGAGATAELGAMRISEE
. :*.**:*** :*::*.* * . :.::**:***:** :****: **
MMAR_2881|M.marinum_M IDALEVIGIRSVSYLASTRVLAGVVVAIPLFCVGLITAYLAARAGTTAIY
MUL_2871|M.ulcerans_Agy99 IDALEVIGIRSVSYLASTRVLAGVVVAIPLFCVGLITAYLAARAGTTAIY
Rv1965|M.tuberculosis_H37Rv IDALEVIGIRSISYLASTRVLAGVVVAVPLFCVGLMTAYLAARVGTTAIY
MSMEG_0345|M.smegmatis_MC2_155 IDALEVIGIRSVSYLASTRVAAGVIVVIPLYCVAVIMSFISSRLGTTVIY
TH_4199|M.thermoresistible__bu IDALEVIGIRSVTYLASTRVLAGVIVVVPLYCVAMIMAFLSARTGTTVIY
Mvan_0362|M.vanbaalenii_PYR-1 IDALEVIGIRSVTYLAATRVLAGVVVVIPLYCIAVMMAFLAARTGTTVIY
Mflv_2100|M.gilvum_PYR-GCK IDALEVMGIRSVAYLASTRVLAGLLVVIPLYCVGVLASFWAARFGTTVIY
MAV_2060|M.avium_104 IDALEVMGIRAVTYLASTRIIAGILVVIPLYAVAVLMSFIAAKLLTIYVY
MAB_4154c|M.abscessus_ATCC_199 IDALETMAVHAISYLVSTRLVAGLIAIIPLYSLSVLAAFFASRATTVMIN
Mb0174|M.bovis_AF2122/97 IDALEVMGIKSISFLASTRIMAGLVVIIPLYALAMIMSFLSPQITTTVLY
MLBr_02588|M.leprae_Br4923 IDALEVMSIKSISFLVTTRILAGLVVIVPLYAVAMIMAFLSPHIITTVLY
*****.:.::::::*.:**: **::. :**:.:.:: :: :.: * :
MMAR_2881|M.marinum_M GQGSGVYDHYFNTFLRPTDVLWSSFEVVVVALMIMLVCTYYGYNAHGGPA
MUL_2871|M.ulcerans_Agy99 GQGSGVYDHYFNTFLRPTDVLWSSFEVVVLALMIMLVCTYYGYNAHGGPA
Rv1965|M.tuberculosis_H37Rv GQGSGVYDHYFNTFLRPTDVLWSSVEVVVVALMIMLVCTYYGYAAHGGPA
MSMEG_0345|M.smegmatis_MC2_155 GQGSGVYDHYFNTFLNTNDLLWSFGQSVAITVVIMLVHTYYGYTASGGPA
TH_4199|M.thermoresistible__bu GQGSGVYDHYFNTFLNPTDLIWSFFQVVALAVVIMLVHTFYGYTASGGPA
Mvan_0362|M.vanbaalenii_PYR-1 GQGSGVYDHYFNTFLNPTDLVWSFLQSVAITVVVMLVHTYYGYTARGGPA
Mflv_2100|M.gilvum_PYR-GCK GQSTGVYDHYFRTFLNPTDLVWSFAQCIVLAIVIMLVHTYYGFSARGGPA
MAV_2060|M.avium_104 GQSKGVYEHYFSTFLRPNDLLWSFFSALAMATGVMVVHTYYGFTATGGPA
MAB_4154c|M.abscessus_ATCC_199 GQSPGVYDHYFNTFLVPTDLLWSFLQAIVMSVVVMLVHTSYGFNASGGPV
Mb0174|M.bovis_AF2122/97 GQSNGTYEHYFQTFLRPDDVFWSFLEALIITAIVMVSHCYYGYAAGGGPV
MLBr_02588|M.leprae_Br4923 GQSNGTYEHYFRTFLRPDDVFWSFLEAVIITAVVMITHCYYGYTANGGPV
**. *.*:*** *** . *:.** . : :: :*: **: * ***.
MMAR_2881|M.marinum_M GVGEAVGRAVRASMVVASIAIVIMTLAIYGQSPNFHLAS
MUL_2871|M.ulcerans_Agy99 GVGEAVGRAVRASMVVASIAIVIMTLAIYGQSPNFHLAS
Rv1965|M.tuberculosis_H37Rv GVGEAVGRAVRASMVVASIAILVMTLAIYGQSPNFHLAT
MSMEG_0345|M.smegmatis_MC2_155 GVGEAVGRAVRTSLIVAAIVVVMISLALYGQSGNFHLAG
TH_4199|M.thermoresistible__bu GVGEAVGRAVRTSMIVAAVVIIFISLAAYGQTGNFVLAG
Mvan_0362|M.vanbaalenii_PYR-1 GVGEAVGRAVRTSMVVAAVEIVMISLAIYGQSGNFNLAG
Mflv_2100|M.gilvum_PYR-GCK GVGEAVGRAVRTSLILSAFVLVMISLAVYGQSGNFNLAG
MAV_2060|M.avium_104 GVGEAVGRSVRSSMIVTAFVCLMISLSVYGQSGNFNLSG
MAB_4154c|M.abscessus_ATCC_199 GVGVAVGQAVRTSLIVVVLVTLFISLAVYGGSGNFNLSG
Mb0174|M.bovis_AF2122/97 GVGEAVGRSMRFSLVSVQVVVLFAALALYGVDPNFNLTV
MLBr_02588|M.leprae_Br4923 GVGEAVGRSMRFSLVSVQVVVLSATLALYGVDPNFALTV
*** ***:::* *:: . : :*: ** ** *: