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M. tuberculosis H37Rv Rv0168 (yrbE1B)

annotation: CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE1B
coordinates: 197660 - 198529
length: 289

MSTAAVLRARFPRAVANLRQYGGAAARGLDEAGQLTWFALTSIGQIAHALRYYRKETLRLIAQIGMGTGA
MAVVGGTVAIVGFVTLSGSSLVAIQGFASLGNIGVEAFTGFFAALINVRIAGPVVTGVALAATVGAGATA
ELGAMRISEEIDALEVMGIKSISFLASTRIMAGLVVIIPLYALAMIMSFLSPQITTTVLYGQSNGTYEHY
FQTFLRPDDVFWSFLEALIITAIVMVSHCYYGYAAGGGPVGVGEAVGRSMRFSLVSVQVVVLFAALALYG
VDPNFNLTV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0168yrbE1B-100% (289)CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE1B
M. tuberculosis H37RvRv0588yrbE2Be-12376.39% (288) integral membrane protein YrbE2b
M. tuberculosis H37RvRv3500cyrbE4B9e-8150.37% (270) integral membrane protein YrbE4b

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0174yrbE1B1e-159100.00% (289) integral membrane protein YRBE1B
M. gilvum PYR-GCKMflv_0712-1e-13080.84% (287) hypothetical protein Mflv_0712
M. leprae Br4923MLBr_02588yrbE1B1e-13985.12% (289) hypothetical protein MLBr_02588
M. abscessus ATCC 19977MAB_4154c-1e-8252.42% (269) hypothetical protein MAB_4154c
M. marinum MMMAR_0411yrbE1B1e-14288.24% (289) integral membrane protein YrbE1B
M. avium 104MAV_5016-1e-14187.54% (289) hypothetical protein MAV_5016
M. smegmatis MC2 155MSMEG_0133-1e-11770.59% (289) ABC-transporter integral membrane protein
M. thermoresistible (build 8)TH_4238-1e-12374.74% (289) PUTATIVE protein of unknown function DUF140
M. ulcerans Agy99MUL_1061yrbE1B1e-14187.54% (289) integral membrane protein YrbE1B
M. vanbaalenii PYR-1Mvan_0133-1e-12980.28% (289) hypothetical protein Mvan_0133

CLUSTAL 2.0.9 multiple sequence alignment


Rv0168|M.tuberculosis_H37Rv         ----------MS-TAAVLRARFPRAVANLRQYGGAAARGLDEAGQLTWFA
Mb0174|M.bovis_AF2122/97            ----------MS-TAAVLRARFPRAVANLRQYGGAAARGLDEAGQLTWFA
MMAR_0411|M.marinum_M               ----------MS-TAAVLRARFPRAIANFNRYAGSVTRGLDESGRLAWFI
MUL_1061|M.ulcerans_Agy99           ----------MS-TAAVLRARFPRAIANFNRYAGSVTRGLDESGRLAWFI
MLBr_02588|M.leprae_Br4923          ----------MS-TAAVLRARFPRAAANLNRYGGAAARGIDDIGQMSWFG
MAV_5016|M.avium_104                ----------MS-TAAVFRSRFPRAAENLNRYGLAAARGLDDVGQMAWFG
Mflv_0712|M.gilvum_PYR-GCK          ----------MSDTAAVLRSRFPRGVARAEKIVGAPGRGLDSIGHVAWFV
Mvan_0133|M.vanbaalenii_PYR-1       ----------MS-TSAVLRSRFPRGVATAEKWAGAPARGLEAMGHVAVFV
TH_4238|M.thermoresistible__bu      VFGSERGADMTVETGTVLRQRFPRAYSTGQRWVGAPARGLNSVGHVAWFV
MSMEG_0133|M.smegmatis_MC2_155      ----------MS-TVQVLRSRFPRAFSRSSEIAATPARFLDSMGHVAWFV
MAB_4154c|M.abscessus_ATCC_199      ----------MS--GPYLSTHTVTSYT--VRYMRGLGRSFDKFGEQALFY
                                                     :  :   .     .      * ::  *. : * 

Rv0168|M.tuberculosis_H37Rv         LTSIGQIAHALRYYRKETLRLIAQIGMGTGAMAVVGGTVAIVGFVTLSGS
Mb0174|M.bovis_AF2122/97            LTSIGQIAHALRYYRKETLRLIAQIGMGTGAMAVVGGTVAIVGFVTLSGS
MMAR_0411|M.marinum_M               LTSLGQSGHALRYYRKEILRLIAQIGMGTGAMAVVGGTAAIVGFVTLSGS
MUL_1061|M.ulcerans_Agy99           LTSLGQSGHALRYYRKEILRLIAQIGMGTGAMAVVGGTAAIVGFVTLSGS
MLBr_02588|M.leprae_Br4923          LIALGNIPNALSRYRKETLRLIAQIGMGTGAMAVVGGTAAIVGFVTLSGS
MAV_5016|M.avium_104                GVALAHIPHALSHYRKETLRLIAQIGMGTGAMAVIGGTVAIVGFVTLSGS
Mflv_0712|M.gilvum_PYR-GCK          VTAVGSIGHAVRYYRKEMLRLIAEIGMGTGAMAVVGGTVAIVGFVTLSGS
Mvan_0133|M.vanbaalenii_PYR-1       VTAVGSIGHALRFYRREMLRLIAEIGMGTGAMAVVGGTVAIVGFVTLSGS
TH_4238|M.thermoresistible__bu      VQAVGMIGHALRHYRRELLRLVAEIGMGTGAMAVVGGTVAIVGFVTLSGG
MSMEG_0133|M.smegmatis_MC2_155      VQAIVHVPHAFRHYRRESLRLVAEIGMGTGAMAVIGGTVAIIGFVTLSAG
MAB_4154c|M.abscessus_ATCC_199      AQSLSYIPAALTKYRKETIRVLAEITMGTGALVMIGGTVGVAVFLTLASG
                                      ::     *.  **:* :*::*:* *****:.::***..:  *:**:..

Rv0168|M.tuberculosis_H37Rv         SLVAIQGFASLGNIGVEAFTGFFAALINVRIAGPVVTGVALAATVGAGAT
Mb0174|M.bovis_AF2122/97            SLVAIQGFASLGNIGVEAFTGFFAALINVRIAGPVVTGVALAATVGAGAT
MMAR_0411|M.marinum_M               SLIAIQGFASLGNIGVEAFTGFFSALVNVRIAGPVVTGVALAATVGAGAT
MUL_1061|M.ulcerans_Agy99           SLIAIQGFASLGNIGVEAFTGFFSALVNVRIAGPVVTGVALAATVGAGAT
MLBr_02588|M.leprae_Br4923          SLVAIQGFASLGAIGVEAFTGFFAALINVRIAAPVITGIVMAATVGAGAT
MAV_5016|M.avium_104                SLVAIQGFASLGNIGVEAFTGFFAALINVRIAAPVVTGIAMAATVGAGAT
Mflv_0712|M.gilvum_PYR-GCK          SLVAIQGFASLGNIGVEAFTGFFAALINVRIAAPVVAGQALAATVGAGAT
Mvan_0133|M.vanbaalenii_PYR-1       SLVAIQGFASLGNIGVEAFTGFFAALINVRIAAPVVAGQALAATVGAGAT
TH_4238|M.thermoresistible__bu      SLIAIQGFASLGNIGVEAFTGFFAALVNVRIAAPVVAGQALAATVGAGAT
MSMEG_0133|M.smegmatis_MC2_155      SLIAIQGFASLGNIGVEAFTGFFAALANIRVVAPVVTGQALAATVGAGAT
MAB_4154c|M.abscessus_ATCC_199      GVIAVQGYSSLGNIGIEALTGFLSAFLNVRIVAPVVAGIAMAATIGAGTT
                                    .::*:**::*** **:**:***::*: *:*:..**::* .:***:***:*

Rv0168|M.tuberculosis_H37Rv         AELGAMRISEEIDALEVMGIKSISFLASTRIMAGLVVIIPLYALAMIMSF
Mb0174|M.bovis_AF2122/97            AELGAMRISEEIDALEVMGIKSISFLASTRIMAGLVVIIPLYALAMIMSF
MMAR_0411|M.marinum_M               AELGAMRISEEIDALEVMGIKSISYLASTRIMAGLVVIIPLYALAMIMSF
MUL_1061|M.ulcerans_Agy99           AELGAMRISEEIDALEVMGIQSISYLASTRIMAGLVVIIPLYALAMIMSF
MLBr_02588|M.leprae_Br4923          AELGAMRISEEIDALEVMSIKSISFLVTTRILAGLVVIVPLYAVAMIMAF
MAV_5016|M.avium_104                AELGAMRISEEIDALEVMGIKSISFLATTRIMAGLVVIIPLYALAMIMSF
Mflv_0712|M.gilvum_PYR-GCK          AELGAMRISEEIDALEVMGIKSISYLVSTRIVAGFVVIIPLYAMAIIMSF
Mvan_0133|M.vanbaalenii_PYR-1       AELGAMRISEEIDALEVMGIKSISYLVSTRIMAGFVVIIPLYAMAIIMSF
TH_4238|M.thermoresistible__bu      AELGAMRISEEVDALEVMAIRSISYLVSTRIIAGFIVIIPLYAMAIIMSF
MSMEG_0133|M.smegmatis_MC2_155      AELGAMRISEEVDALEVMGIKSISYLVSTRIMAGAIVIIPLYAMAILLSF
MAB_4154c|M.abscessus_ATCC_199      AQLGAMRVAEEIDALETMAVHAISYLVSTRLVAGLIAIIPLYSLSVLAAF
                                    *:*****::**:****.*.:::**:*.:**::** :.*:***::::: :*

Rv0168|M.tuberculosis_H37Rv         LSPQITTTVLYGQSNGTYEHYFQTFLRPDDVFWSFLEALIITAIVMVSHC
Mb0174|M.bovis_AF2122/97            LSPQITTTVLYGQSNGTYEHYFQTFLRPDDVFWSFLEALIITAIVMVSHC
MMAR_0411|M.marinum_M               FSPQMVTTVLYGQSSGTYEHYFRTFLRPDDVFWSFLEAIIIAAIVMVTHC
MUL_1061|M.ulcerans_Agy99           FSPQMVTTVLYGQSSGTYEHYFRTFLRPDDVFWSFLEAIIIAAIVMVTHC
MLBr_02588|M.leprae_Br4923          LSPHIITTVLYGQSNGTYEHYFRTFLRPDDVFWSFLEAVIITAVVMITHC
MAV_5016|M.avium_104                LSPQITTTVLYGQSNGTYEHYFRTFLRPDDVFWSFLEAIIITAVVMITHC
Mflv_0712|M.gilvum_PYR-GCK          LSAQATTTIFYGQSTGTYEHYFRTFLRPDDVFWSFVQAVIISVIVMLNHC
Mvan_0133|M.vanbaalenii_PYR-1       LSAQVTTTVFYGQSVGTYEHYFRTFLRPDDVFWSFIQAVIISVIVMLNHC
TH_4238|M.thermoresistible__bu      LSAQVTTTFFYGQSVGTYDHYFRTFLRPDDVMWSFVQAIIISVIVMLNHC
MSMEG_0133|M.smegmatis_MC2_155      MSAQLVTTIFYSQSVGTYEHYFHTFLRVDDVMWSFLEVIIMSVIVMLNHC
MAB_4154c|M.abscessus_ATCC_199      FASRATTVMINGQSPGVYDHYFNTFLVPTDLLWSFLQAIVMSVVVMLVHT
                                    ::.:  *..: .** *.*:***.***   *::***::.::::.:**: * 

Rv0168|M.tuberculosis_H37Rv         YYGYAAGGGPVGVGEAVGRSMRFSLVSVQVVVLFAALALYGVDPNFNLTV
Mb0174|M.bovis_AF2122/97            YYGYAAGGGPVGVGEAVGRSMRFSLVSVQVVVLFAALALYGVDPNFNLTV
MMAR_0411|M.marinum_M               YYGYNAGGGPVGVGEAVGRSMRFSLVSVNVVVLCAALALYGVNPNFALTV
MUL_1061|M.ulcerans_Agy99           YYGYNAGGGPVGEGEAVGRSMRFSLVSVNVVVLCAALALYGVNPNFALTV
MLBr_02588|M.leprae_Br4923          YYGYTANGGPVGVGEAVGRSMRFSLVSVQVVVLSATLALYGVDPNFALTV
MAV_5016|M.avium_104                FYGYNAGGGPVGVGEAVGRSMRFSLVSVQVVVLAAALALYGVNPNFALTV
Mflv_0712|M.gilvum_PYR-GCK          YYGFYASGGPVGVGEAVGRSMRASLVAIVCVVLFASLALYGVDPNFNLTV
Mvan_0133|M.vanbaalenii_PYR-1       YYGFYASGGPVGVGEAVGRSMRASLVAIVVVVLLASLALYGVDPNFNLTV
TH_4238|M.thermoresistible__bu      YYGYYASGGPVGVGEAVGRSMRASLVAIVLVVLLASLALYGTDPNFNLTV
MSMEG_0133|M.smegmatis_MC2_155      YFGYFASGGAVGVGEAVGRSMRTSLIAIVLVVLLASLALYGTDPNFNLTV
MAB_4154c|M.abscessus_ATCC_199      SYGFNASGGPVGVGVAVGQAVRTSLIVVVLVTLFISLAVYGGSGNFNLSG
                                     :*: *.**.** * ***:::* **: :  *.*  :**:** . ** *: