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VPVDLRRDWPTPLRQAGFDPNQPSAWLAEGLLAFLPPDAQDRLLDNITALSAPGSR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1888A | - | - | 100% (57) | hypothetical protein Rv1888A |
| M. tuberculosis H37Rv | Rv0726c | - | 1e-20 | 73.68% (57) | hypothetical protein Rv0726c |
| M. tuberculosis H37Rv | Rv3787c | - | 9e-20 | 66.67% (57) | hypothetical protein Rv3787c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1921c | - | 1e-29 | 100.00% (57) | hypothetical protein Mb1921c |
| M. gilvum PYR-GCK | Mflv_5024 | - | 9e-23 | 78.57% (56) | putative methyltransferase |
| M. leprae Br4923 | MLBr_02640 | - | 2e-16 | 64.29% (56) | hypothetical protein MLBr_02640 |
| M. abscessus ATCC 19977 | MAB_3787 | - | 9e-19 | 67.86% (56) | hypothetical protein MAB_3787 |
| M. marinum M | MMAR_1059 | - | 4e-22 | 77.19% (57) | O-methyltransferase |
| M. avium 104 | MAV_4441 | - | 6e-21 | 75.44% (57) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_1480 | - | 5e-21 | 76.79% (56) | methyltransferase |
| M. thermoresistible (build 8) | TH_4502 | - | 6e-20 | 75.00% (56) | PUTATIVE methyltransferase |
| M. ulcerans Agy99 | MUL_0818 | - | 3e-22 | 77.19% (57) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1345 | - | 9e-22 | 76.79% (56) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1888A|M.tuberculosis_H37Rv --------------------------------------------------
Mb1921c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_5024|M.gilvum_PYR-GCK --MART-----DGDTWDLASSVGATATSVAASRAFASR----GPDALIDD
Mvan_1345|M.vanbaalenii_PYR-1 --MART-----EGDTWDLGSSVGATATSVAANRAFASRSTAGGPEPLLND
MSMEG_1480|M.smegmatis_MC2_155 --MTRT-----DGDTWDLATSVGSTATGVAAMRALATR----QPDPLIDD
MMAR_1059|M.marinum_M --MTSTGSTRYDGDSWDLASSVGVTATMVAAARAMATR----AENPLIND
MUL_0818|M.ulcerans_Agy99 --MTSTGSTRYDGDSWDLASSVGVTATMVAAARAMATR----AENPLIND
MAV_4441|M.avium_104 --MTST---RYEGDTWDLASSVGVTATMVAAARAMATR----ADNPLIND
MAB_3787|M.abscessus_ATCC_1997 --MART-----DDDSWDLASSVGATATMVAAQRALASH----VPNPLIND
MLBr_02640|M.leprae_Br4923 ---MRT-----HDDTWDIKTSVGTTAVMVAAARAAETD----RPDALIRD
TH_4502|M.thermoresistible__bu MSSLRT-----DDDTWDIATSVGSTAVMVAASRAAETE----REDALIRD
Rv1888A|M.tuberculosis_H37Rv --------------------------------------------------
Mb1921c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_5024|M.gilvum_PYR-GCK PYARLLVEAVGLPHFVKVARGEIDFDGDP----------LFGAQQAINQI
Mvan_1345|M.vanbaalenii_PYR-1 PYADLLVEAVGLPHFIRVARGEIDFDDDP----------LFGARQMLEQI
MSMEG_1480|M.smegmatis_MC2_155 PYADALVKAVGLEHCIALADGETCVEGDP----------MLDLNRMCEQI
MMAR_1059|M.marinum_M PYAEPLVRAVGVDLLTRLATGEFNVADLD---DDPQRPLGPLGD-VADNM
MUL_0818|M.ulcerans_Agy99 PYAEPLVRAVGVDLLTRLATGEFNVADLD---DDPQRPLGPIGD-VADNM
MAV_4441|M.avium_104 PFAEPLVKAVGVDLLSRLAGGELDPAELNDVHDGAAGSAGAMSR-MADNM
MAB_3787|M.abscessus_ATCC_1997 PYAEPLVRAVGIEYFTKLASGAFDPEQMAG-----LVQLGITADGMANGM
MLBr_02640|M.leprae_Br4923 PYAKLLVTNTGAGALWEAMLDPSMVAKVEA----IDAEAAAMVEHMRSYQ
TH_4502|M.thermoresistible__bu PYAKVLVAGAGTG-VWELILDDDFTAKIEA----ADPETAAIFDHMGNYQ
Rv1888A|M.tuberculosis_H37Rv --------------------------------------------------
Mb1921c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_5024|M.gilvum_PYR-GCK VVRTRIFDDFLTDAGQR-EPQIRQAVILASGLDTRAYRLDWPAGTVVYEI
Mvan_1345|M.vanbaalenii_PYR-1 TVRTRHFDDFFAGAMAAGPPKIRQAVILASGLDTRAYRLPWPAGTVVYEI
MSMEG_1480|M.smegmatis_MC2_155 AVRTRYFDELFIAAGAD---GVRQAVILASGLDTRAYRLDWPAGTVVFEV
MMAR_1059|M.marinum_M AVRTRFFDDFFLDATRA---GLEQVVILASGLDARAYRLPWPPQTVVYEI
MUL_0818|M.ulcerans_Agy99 AVRTRFFDDFFLAATRA---GLEQVVILASGRDARAYRLPWPPQTVVYEI
MAV_4441|M.avium_104 AVRTKFFDEFFLNATKA---GIAQVVILASGLDARAYRLAWPAGTVVYEV
MAB_3787|M.abscessus_ATCC_1997 ASRTWYYDTAFESSTAA---GVRQAVILASGLDTRAYRLTWPAGTTVYEL
MLBr_02640|M.leprae_Br4923 AVRTNFFDTYFNNAVID---GIRQFVILASGLDSRAYRLDWPTGTTVYEI
TH_4502|M.thermoresistible__bu AVRTHFFDTYFARAAEA---GIRQVVILASGLDSRAYRLPWPDGTVVYEI
Rv1888A|M.tuberculosis_H37Rv -------------------------MVPVDLRRDWPTPLRQAGFDPNQPS
Mb1921c|M.bovis_AF2122/97 -------------------------MVPVDLRRDWPTPLRQAGFDPNQPS
Mflv_5024|M.gilvum_PYR-GCK DQPEVIDFKTAVLTDAGVAPAADRRTVGIDLREDWPTALRDAGFDPDRPT
Mvan_1345|M.vanbaalenii_PYR-1 DQPTVIEFKTAVLADAGVAPTAERRTVGIDLREDWPAALRGAGFDPTRPT
MSMEG_1480|M.smegmatis_MC2_155 DQPQVIEFKTRTLADLGAQPTAERRTVAVDLRDDWPAALRDAGFDPAEPT
MMAR_1059|M.marinum_M DLPQVIEFKSRTLADLGAAPTADRRVVAVDLREDWPAALRAAGFDPNQPT
MUL_0818|M.ulcerans_Agy99 DLPQVIDFKSRTLADLGAAPTADRRVVAVDLREDWPAALRAAGFDPNQPT
MAV_4441|M.avium_104 DQPQVIDFKTTALAQLGAAPTAERRVVAVDLRDDWPAALRAAGFDPTRPT
MAB_3787|M.abscessus_ATCC_1997 DQPEVITFKTDTLAELGASPSAERRTVAIDLREDWPAALQAAGFDPEQPT
MLBr_02640|M.leprae_Br4923 DQPKVLAYKSTTLAEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSART
TH_4502|M.thermoresistible__bu DQPKVLEYKSATLAAHGVQPAADRREVAVDLRHDWPKALRAKGFDPQQRT
* :*** *** .*: **** :
Rv1888A|M.tuberculosis_H37Rv AWLAEGLLAFLPPDAQDRLLDNITALSAPGSR------------------
Mb1921c|M.bovis_AF2122/97 AWLAEGLLAFLPPDAQDRLLDNITALSAPGSR------------------
Mflv_5024|M.gilvum_PYR-GCK AWIAEGLLPYLPPDAQDRLLDSITALSAPGSRLATEHMDAKALTGDW---
Mvan_1345|M.vanbaalenii_PYR-1 AWIAEGLLIYLPPDAQDRLLDHITALSAPGSRLATEHMDAKALTGEW---
MSMEG_1480|M.smegmatis_MC2_155 AWIAEGLLIYLPAEAQDRLLDNITALSAPGSRLATEHMDHRILAEGA---
MMAR_1059|M.marinum_M AWSAEGLLGYLPPEAQDRLLDTVTELSAPGSRLAAECLSSVDPGEEEQIK
MUL_0818|M.ulcerans_Agy99 AWSAEGLLGYLPPEAQDRLLDTVTELSAPGSRLAAECLSGVDPAEEEQIK
MAV_4441|M.avium_104 AWSAEGLLGYLPPEAQDRLLDTITELSAPGSRLATESAPNPAPGEEEKLK
MAB_3787|M.abscessus_ATCC_1997 VWSAEGLLIYLPPEAQDRLFASITELSAPGSRLVCEQVPGLETADFS---
MLBr_02640|M.leprae_Br4923 AWLAEGLLMYLPATAQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQ
TH_4502|M.thermoresistible__bu AWLAEGLLMYLPADAQDRLFENITALSAPGSRLAVETAAEEPVDRREQMR
.* ***** :**. *** *: : *** ***
Rv1888A|M.tuberculosis_H37Rv --------------------------------------------------
Mb1921c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_5024|M.gilvum_PYR-GCK --AKAMTERARRHGSDIDLTKLFYNGE-RRSATEHLGAVGWQTSVQTSND
Mvan_1345|M.vanbaalenii_PYR-1 --ARAMTERARRHGSDVNLSELFYSGP-RTSATEHLRAQGWQTEVLSSND
MSMEG_1480|M.smegmatis_MC2_155 --GKRIGEWSRRVGSSLDIADLFYTGE-RNTAGDYLRGLGWQVTVRPSKE
MMAR_1059|M.marinum_M ERMQEVSARWRAHGFDVDMVGLVYFGD-RNEAVPYLSDRGWLLTSTPLPE
MUL_0818|M.ulcerans_Agy99 ERMQEVSARWRAHGFDVDMVGLVYFGD-RNEAVPYLSDRGWLLTSTPLPE
MAV_4441|M.avium_104 ERMQAISQRWRAHGFDLDMAGLVYFGE-RNEAAPYLAGHGWRLNSVTIRD
MAB_3787|M.abscessus_ATCC_1997 -KARELTRQFAGETLDLDLESLVYTQE-RQMAADWLAEHGWTVITEENDE
MLBr_02640|M.leprae_Br4923 LRFRRVSDALG-FEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPD
TH_4502|M.thermoresistible__bu ARMERIASQFG-LEKALDVAQLMYDDPDRADVPEWLTGHGWRTEWVSAPD
Rv1888A|M.tuberculosis_H37Rv -----------------------------------------------
Mb1921c|M.bovis_AF2122/97 -----------------------------------------------
Mflv_5024|M.gilvum_PYR-GCK AYIANGFGP---------IRDDLLAMIGDSGYLTAWRP---------
Mvan_1345|M.vanbaalenii_PYR-1 AYQAQGFAP---------VADHLVAMIGDSGYLTARLD---------
MSMEG_1480|M.smegmatis_MC2_155 AYADHGFE----------LPEEMAELSGDSGYLSAHLK---------
MMAR_1059|M.marinum_M LRAANGLAP---------AAVDDDGPSVDMLYVSGTLYTTPRPDPAP
MUL_0818|M.ulcerans_Agy99 LRAANGLAP---------AAVDDDGPSVDMLYVSGTLYTTPRPDPAP
MAV_4441|M.avium_104 LFAANGLDP---------LD-DDDTRMGEMLYTWG-IYE--------
MAB_3787|M.abscessus_ATCC_1997 LYARLNLDP---------PNPLLRSIFPNIVYVDATLG---------
MLBr_02640|M.leprae_Br4923 EMRRVGRW-------GDGVPMAD-DKDAFAEFVTAHRL---------
TH_4502|M.thermoresistible__bu EMRRLDRFVAAAMPPGDDADAADLDDTAFSKFVTAERPS--------