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ILLVPILIITLMYFMFENVPHRPGTPSGFNTACLVLLGLFPLFVMFVITAITMQRERASGTLERILTTPL RRLDLLAGYGTAFSIAAAAQATLACIVAFWFLGFDTAGSPVWVFAIAIVNAVLGVGLGLLCSAFARTEFQ AVQFIPLVMVPQLLLAGIIVPRALMPTWLEWISNVMPASYALEALQQVGAHPELTGIAVRDVVVVLSFAV ASLCLAAVTLRRRTS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1686c | - | - | 100% (226) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER |
| M. tuberculosis H37Rv | Rv2938 | drrC | 7e-06 | 24.47% (188) | daunorubicin-DIM-transport integral membrane protein ABC |
| M. tuberculosis H37Rv | Rv1457c | - | 3e-05 | 26.11% (157) | unidentified antibiotic-transport integral membrane ABC |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1712c | - | 1e-124 | 99.56% (226) | integral membrane protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_3681 | - | 7e-06 | 25.40% (189) | multidrug ABC transporter inner membrane protein |
| M. leprae Br4923 | MLBr_02350 | - | 3e-08 | 24.32% (222) | putative antibiotic resistance membrane protein |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2485 | - | 1e-112 | 87.11% (225) | antibiotic resistance ABC transporter, efflux protein |
| M. avium 104 | MAV_3086 | - | 1e-112 | 88.89% (225) | ABC transporter efflux protein, DrrB family protein |
| M. smegmatis MC2 155 | MSMEG_3763 | - | 1e-100 | 78.67% (225) | ABC transporter efflux protein, DrrB family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1665 | - | 1e-110 | 85.33% (225) | antibiotic resistance ABC transporter, efflux protein |
| M. vanbaalenii PYR-1 | Mvan_3297 | - | 1e-100 | 78.22% (225) | multidrug ABC transporter inner membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1686c|M.tuberculosis_H37Rv -------------------------------------------------M
Mb1712c|M.bovis_AF2122/97 -------------------------------------------------M
MMAR_2485|M.marinum_M -------------------------------------------------M
MUL_1665|M.ulcerans_Agy99 -------------------------------------------------M
MAV_3086|M.avium_104 -----------------------------------------------MAM
MSMEG_3763|M.smegmatis_MC2_155 -------------------MSVRRPGSRAYLATTTRILRQLAGDHRSVAM
Mvan_3297|M.vanbaalenii_PYR-1 -------------------MTPR-----AYIATTARILRQLAGDHRSVAM
MLBr_02350|M.leprae_Br4923 MITMISQTVGLVPASLQYPNNSVRALVSQTLLQTKRLLTRWARDYVTIIG
Mflv_3681|M.gilvum_PYR-GCK ------MSVENRFAPGTFTPDPRPAKVPKMLAAQFALELRLLLRN---GE
Rv1686c|M.tuberculosis_H37Rv ILLVPILIITLMYFMFENVPHRPGTPSGFNTACLVLLGLFPLFVMFVITA
Mb1712c|M.bovis_AF2122/97 ILLVPILIITLMYFMFENFPHRPGTPSGFNTACLVLLGLFPLFVMFVITA
MMAR_2485|M.marinum_M ILLVPVLVITLMYFMFENAPHRPGTQTPFNNACLILLGLFPLFVMFIITS
MUL_1665|M.ulcerans_Agy99 ILLVPVLVITLMYFMFENAPHRPGTQTPFNNACLILLGLFPLVVIFIITS
MAV_3086|M.avium_104 ILLVPVLVITLMYFMFENAPHRPGGPTPFNNACLVLLGLFPLFVMFIITA
MSMEG_3763|M.smegmatis_MC2_155 ILLVPSLIITLIYFMFDDVPQRPGAPSPFNTACLIMLGVFPLIVMFLITS
Mvan_3297|M.vanbaalenii_PYR-1 ILVVPTLVITLMYFMFAEVPQRPGAPSPFNNACLIMLGVFPLIVMFLITS
MLBr_02350|M.leprae_Br4923 ALVLPILFLVVLNIVLGNLAYVVTYDSGLY-SFVPLITLGAAITGSTFVA
Mflv_3681|M.gilvum_PYR-GCK QLLLTMFIPITLLIGLILLPLGSFGPNRAATFVPAIMALAVISTAFTGQA
*::. :. : : : . . :: : . :
Rv1686c|M.tuberculosis_H37Rv ITMQRERASGTLERILTTPLRRLDLLAGYGTAFSIAAAAQATLACIVAFW
Mb1712c|M.bovis_AF2122/97 ITMQRERASGTLERILTTPLRRLDLLAGYGTAFSIAAAAQATLACIVAFW
MMAR_2485|M.marinum_M ITMQRERASGTLERVLTTPLRRLDMLAGYGTAFSLAAAAQATVACIVSFW
MUL_1665|M.ulcerans_Agy99 FTMQRERASGTSERVLTTPLRRLDMLAGYGTAFSLAAAAQATVACIVSFW
MAV_3086|M.avium_104 ITMQRERASGTLERILTTPLRRLDLLIAYGTAFSLAAAAQAILACIVSFW
MSMEG_3763|M.smegmatis_MC2_155 ITMQRERVSGTLERILTTPLRRFDLLAAYGTAFSLAAAAQATLACTVAFW
Mvan_3297|M.vanbaalenii_PYR-1 ITMQRERVSGTLERILTTPLRRLDLLAAYGTAFALAAAAQAVFACAVSFW
MLBr_02350|M.leprae_Br4923 IDLVRERSIGLLSRLWVLPIHRASGLLAR-ILANTIRTFVTTLVMLVTGV
Mflv_3681|M.gilvum_PYR-GCK IAVAFDRRYGALKRLGATALPVWGVIAGKSLAVVTVVSLQSVLFGAIGFA
: : :* * .*: . .: . : . : : . :
Rv1686c|M.tuberculosis_H37Rv FLGFDTAGSPVWVFAIAIVNAVLGVGLGLLCS--AFARTEFQAVQFIPLV
Mb1712c|M.bovis_AF2122/97 FLGFDTAGSPVWVFAIAIVNAVLGVGLGLLCS--AFARTEFQAVQFIPLV
MMAR_2485|M.marinum_M LLGFDTAGSPVWVFVIAVVNAILGVGLGLLFS--AFARTEFQAVQFIPLV
MUL_1665|M.ulcerans_Agy99 LLGFDTAGSPVWVFVIAVVNAILGVGLGLLFS--AFARTEFQAVQFIPLV
MAV_3086|M.avium_104 LLGFDTAGSPVWVFVIAIVNAVLGVGLGLLCS--AFARTEFQAVQFIPLV
MSMEG_3763|M.smegmatis_MC2_155 LLGFHTEGSPLLVVGIAIVNAVLGVGLGLLCS--AFARTEFQAVQFMPLV
Mvan_3297|M.vanbaalenii_PYR-1 LLGLDTAGSALWVFAIAIVNAVLGVGLGLLCS--AFARTEFQAVQFMPLV
MLBr_02350|M.leprae_Br4923 ILGFRFRQGVIASLMWVSVPVIFGIAIAVMVTTVALYTEQTFVVEAVELV
Mflv_3681|M.gilvum_PYR-GCK LGWRPPLAGLALGALIIALGTAVFAALGLLLG---GTLRAEIVLALANLL
: . : . . .:.:: .: *:
Rv1686c|M.tuberculosis_H37Rv MVPQLLLAGIIVPRALMPTWLEWISNVMPASYALEALQQVGAHPELTGIA
Mb1712c|M.bovis_AF2122/97 MVPQLLLAGIIVPRALMPTWLEWISNVMPASYALEALQQVGAHPELTGIA
MMAR_2485|M.marinum_M MVPQLLLAGIIVPRAVMPTWLEWVSNAMPASYALEALQQVGAHPELTYIA
MUL_1665|M.ulcerans_Agy99 MVPQLLLAGIIVPRAVMPTWLEWVSNAMPASYALEALQQVGAHPELTYIA
MAV_3086|M.avium_104 MVPQLLLAGIIVPRALMPHWLQWISNVLPASYALEALQQVGTHPELTFIA
MSMEG_3763|M.smegmatis_MC2_155 IAPQLLLCGIIVPRAALPEWLQWVSNALPASYALEALQEVGAYPDLTATA
Mvan_3297|M.vanbaalenii_PYR-1 IAPQLLLCGIVVPRAQLPDWLQWISNALPASYALEALQEVNAHPELTSVA
MLBr_02350|M.leprae_Br4923 QAIAVFLSTGLVPLNQYPGWIQPLVAHQPVSYAIAAMRGLSMGGPVLASM
Mflv_3681|M.gilvum_PYR-GCK WFVFAGLGALVLERGMVPAAVQWVARLTPSG----ALTEALVQAMTLSVD
* :: * :: : * . *:
Rv1686c|M.tuberculosis_H37Rv VRDVVVVLSFAVASLCLAAVTLRRRTS-
Mb1712c|M.bovis_AF2122/97 VRDVVVVLSFAVASLCLAAVTLRRRTS-
MMAR_2485|M.marinum_M LRDIVVVVVFAVASLCLAAATLRRRTP-
MUL_1665|M.ulcerans_Agy99 LRDIVVVVVFAVASLCLAAATLRRRTP-
MAV_3086|M.avium_104 VRDIVVVLGFALAALCLAAATLRRRTP-
MSMEG_3763|M.smegmatis_MC2_155 VRDISVVVGFAVLALCLAAATLRRRTP-
Mvan_3297|M.vanbaalenii_PYR-1 VRDIAVVLGFTVISLTLAAATLRRRTP-
MLBr_02350|M.leprae_Br4923 VAMLVWTAGICASCAVPLGVGYRRACTH
Mflv_3681|M.gilvum_PYR-GCK WFGLLVLAAWGAVAALCALRWFRFV---
: . *