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M. tuberculosis H37Rv Rv1457c (-)

annotation: PROBABLE UNIDENTIFIED ANTIBIOTIC-TRANSPORT INTEGRAL MEMBRANE ABC TRANSPORTER
coordinates: 1642537 - 1643322
length: 261

TQTNRPAFPAGTFSPDPRPNAVPLMLAAQFSLELKLLLRNGEQLLLTMFIPITLLVGLTLLPMGSFGHNR
AATFVPVIMALAVISTAFTGQAIAVAFDRRYGALKRLGATPLPVWGIIAGKSLAVVAVVFLQAIILGAIG
FALGWRPALTALTLGAGIIALGTAGFAALGLLLGGTLRAEIVLAVANLMWFVFAGFGALTLESNVIPTAF
KWVARVTPSGALTEALSQAMTVSVDWFGIVVLAVWGALAALAALRWFRFT*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1457c--100% (261)PROBABLE UNIDENTIFIED ANTIBIOTIC-TRANSPORT INTEGRAL MEMBRANE ABC TRANSPORTER
M. tuberculosis H37RvRv1686c-4e-0526.11% (157) integral membrane protein ABC transporter
M. tuberculosis H37RvRv0226c-4e-0526.88% (186) transmembrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1492c-1e-144100.00% (261) unidentified antibiotic-transport integral membrane ABC
M. gilvum PYR-GCKMflv_3681-1e-11481.75% (252) multidrug ABC transporter inner membrane protein
M. leprae Br4923MLBr_00589-1e-12283.08% (260) hypothetical protein MLBr_00589
M. abscessus ATCC 19977MAB_2753-1e-10472.83% (265) ABC transporter permease
M. marinum MMMAR_2262-1e-12888.17% (262) antibiotic ABC transporter transmembrane protein
M. avium 104MAV_3322-1e-12184.11% (258) ABC transporter efflux protein, DrrB family protein
M. smegmatis MC2 155MSMEG_3118-1e-11580.08% (261) ABC transporter efflux protein, DrrB family protein
M. thermoresistible (build 8)TH_0342-1e-11078.85% (260) PROBABLE UNIDENTIFIED ANTIBIOTIC-TRANSPORT INTEGRAL MEMBRANE
M. ulcerans Agy99MUL_1858-1e-12887.79% (262) antibiotic ABC transporter transmembrane protein
M. vanbaalenii PYR-1Mvan_2729-1e-11682.17% (258) multidrug ABC transporter inner membrane protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3681|M.gilvum_PYR-GCK          MS------VENRFAPGTFTPDPRPAKVPKMLAAQFALELRLLLRNGEQLL
Mvan_2729|M.vanbaalenii_PYR-1       MT------TENRFTPGTFTPDPRPAPVPRMLAAQFRLELRLLLRNGEQLL
MSMEG_3118|M.smegmatis_MC2_155      MTSP----AANRFAPGTFTPDPRPATVQKMLAAQFGLELRLLLRNGEQLL
TH_0342|M.thermoresistible__bu      --------VTNRFPAGTFTPDPRPAPVPRMLAAQYGLELKLLLRNGEQLL
Rv1457c|M.tuberculosis_H37Rv        MTQTN----RPAFPAGTFSPDPRPNAVPLMLAAQFSLELKLLLRNGEQLL
Mb1492c|M.bovis_AF2122/97           MTQTN----RPAFPAGTFSPDPRPNAVPLMLAAQFSLELKLLLRNGEQLL
MLBr_00589|M.leprae_Br4923          MTQNNTLRNSPLFPAGTFTPNPRPNAVTRMVAAQFMLELKLLLRNGEQLL
MMAR_2262|M.marinum_M               MTQTN---GEGTFPVGTFTPDPRPSAVPRMLAAQFGLELKLLLRNGEQLL
MUL_1858|M.ulcerans_Agy99           MTQTN---GEGTFPVGTFTPDPRPSAVPRMLAAQFGLELKLLLRNGEQLL
MAV_3322|M.avium_104                MTDS------GVFPVGTFTPNPRPSAVPKMLAAQYGLELKLLLRNGEQLL
MAB_2753|M.abscessus_ATCC_1997      MTDTT----TPRFDPGTFTPDPRPSAVHTMLFAQFWLELKLLLRNGEQLL
                                                *  ***:*:***  *  *: **: ***:**********

Mflv_3681|M.gilvum_PYR-GCK          LTMFIPITLLIGLILLPLGSFGPNRAATFVPAIMALAVISTAFTGQAIAV
Mvan_2729|M.vanbaalenii_PYR-1       LTMFIPITLLVGLTLLPLGSFGDNRAATFVPAIMALAVISTAFTGQAIAV
MSMEG_3118|M.smegmatis_MC2_155      LTMFIPITLLIGLTLLPLGSFGDDRAGAFTPAIMALAVISTAFTGQAIAV
TH_0342|M.thermoresistible__bu      LTLFIPITLLVGLILLPLGDFGDDRASRFVPAIMALAVISTAFTGQAIAV
Rv1457c|M.tuberculosis_H37Rv        LTMFIPITLLVGLTLLPMGSFGHNRAATFVPVIMALAVISTAFTGQAIAV
Mb1492c|M.bovis_AF2122/97           LTMFIPITLLVGLTLLPMGSFGHNRAATFVPVIMALAVISTAFTGQAIAV
MLBr_00589|M.leprae_Br4923          LTMFIPITLLIGLTLLPLGSFGHHRATTFVPVIMALAVVSSAFTGQAIAV
MMAR_2262|M.marinum_M               LTMFIPITLLIGLTLLPLGSFGQHRAATFVPVIMALAVISTAFTGQAIAV
MUL_1858|M.ulcerans_Agy99           LTMFIPITLLIGLTLLPLGSFGQHRAATFVPVIMALAVISTAFTGQAIAV
MAV_3322|M.avium_104                LTMFIPITLLVGLTLLPLGSFGQHRAATFTPVIMALAVISTAFTGQAIAV
MAB_2753|M.abscessus_ATCC_1997      LTMFIPITLLIGLTLLPLGQFPGSRTDIFVPAIMALAVISTAFTGQAIAV
                                    **:*******:** ***:*.*   *:  *.*.******:*:*********

Mflv_3681|M.gilvum_PYR-GCK          AFDRRYGALKRLGATALPVWGVIAGKSLAVVTVVSLQSVLFGAIGFALGW
Mvan_2729|M.vanbaalenii_PYR-1       AFDRRYGALKRLGATALPVWGIIAGKSLAVGAVVILQSILFGAIGFALGW
MSMEG_3118|M.smegmatis_MC2_155      AFDRRYGALKRLGATALPVWGIIAGKSLAVVAVVFLQAVLLGAIGVALGW
TH_0342|M.thermoresistible__bu      AFDRRYGALKRLGATALPVWGIIVGKSLAVVTVVFVQSVVLGAIGAALGW
Rv1457c|M.tuberculosis_H37Rv        AFDRRYGALKRLGATPLPVWGIIAGKSLAVVAVVFLQAIILGAIGFALGW
Mb1492c|M.bovis_AF2122/97           AFDRRYGALKRLGATPLPVWGIIAGKSLAVVAVVFLQAIILGAIGFALGW
MLBr_00589|M.leprae_Br4923          AFDRRYGALKRFGATPLPVWGIIAGKSLAVVTVVFLQAIILGAIGVMLGW
MMAR_2262|M.marinum_M               AFDRRYGALKRLGATPLPVWGIIAGKSLAVVAVVFLQAIVLGAIGFALGW
MUL_1858|M.ulcerans_Agy99           AFDRRYGALKRLGATPLPVWGIIAGKSLAVVAVVFLQAIVLGAIGFALGW
MAV_3322|M.avium_104                AFDRRYGALKRLGATPLPVWGIIAGKSLAVVTVVFLQAILLGAIGFALGW
MAB_2753|M.abscessus_ATCC_1997      GFDRRYGALKRLGATALPVWGIIAGKALAVVTVVVLQAAVIGAIGGALGW
                                    .**********:***.*****:*.**:*** :** :*: ::****  ***

Mflv_3681|M.gilvum_PYR-GCK          RPPLAGLALGALIIALGTAVFAALGLLLGGTLRAEIVLALANLLWFVFAG
Mvan_2729|M.vanbaalenii_PYR-1       RPPLAGLALGAVIIALGTAVFAALGLLLGGTLRAEIVLALANLLWFVFAG
MSMEG_3118|M.smegmatis_MC2_155      RPPLAGLALGAVIIALGTAGFAAMGLLLGGTLRSEIVLALANLLWFVFAG
TH_0342|M.thermoresistible__bu      RPQPAGLLLGAVIIALGTAVFAALGLLLGGTLRAEIVLAVANLLWFVFAA
Rv1457c|M.tuberculosis_H37Rv        RPALTALTLGAGIIALGTAGFAALGLLLGGTLRAEIVLAVANLMWFVFAG
Mb1492c|M.bovis_AF2122/97           RPALTALTLGAGIIALGTAGFAALGLLLGGTLRAEIVLAVANLMWFVFAG
MLBr_00589|M.leprae_Br4923          RPALICLALGAAIIALGTAGLAALGLLLGGTLRAEIVLAVANLMWFVFAG
MMAR_2262|M.marinum_M               RPALAALALGGAVIALGTAGFAALGLLLGGTLRAEIVLAVANLMWFVFAG
MUL_1858|M.ulcerans_Agy99           RPALAALALGGAVIALGTAGFAALGLLLGGTLRAEIVLAIANLMWFVFAG
MAV_3322|M.avium_104                RPALAALALGAAVIALGTAVFAALGLLLGGTLRAEIVLALANLMWFVFAG
MAB_2753|M.abscessus_ATCC_1997      RPHPVGLLVGAVVIAIGTAAFVAMGLLLGGTLRAEIVLALANLLWFIFAG
                                    **    * :*. :**:*** :.*:*********:*****:***:**:**.

Mflv_3681|M.gilvum_PYR-GCK          LGALVLERG----MVPAAVQWVARLTPSGALTEALVQAMTLSVDWFGLLV
Mvan_2729|M.vanbaalenii_PYR-1       LGALTLEAG----VVPSTVQWVARLTPSGALTEALTQAMTSSMDWFGLAV
MSMEG_3118|M.smegmatis_MC2_155      FGALTLETE----AVPSALAWVARLTPSGALTEALSQAMTLSVDWFGIAV
TH_0342|M.thermoresistible__bu      FGALTVEPEG--DVVPAAAALVARLTPSGALTDALSQAMTLSVNWFAVAV
Rv1457c|M.tuberculosis_H37Rv        FGALTLESN----VIPTAFKWVARVTPSGALTEALSQAMTVSVDWFGIVV
Mb1492c|M.bovis_AF2122/97           FGALTLESN----VIPTAFKWVARVTPSGALTEALSQAMTVSVDWFGIVV
MLBr_00589|M.leprae_Br4923          LGALTVKMN----MISAVVKWAARLTPSGALTEALSQAMTLSVDWFGVII
MMAR_2262|M.marinum_M               FGALTVETD----VIPTAVKWAARLTPSGALTEALSRAMVLSVDWFGVVV
MUL_1858|M.ulcerans_Agy99           FGALTVETD----VIPTAVKWAARLTPSGALTEALSRAMVLSVDWFGVVV
MAV_3322|M.avium_104                LGALTVDSG----VIPAGVKWAARLTPSGALTEALSRAMTLSADWFGMAV
MAB_2753|M.abscessus_ATCC_1997      LGALTLEDGRTTDAIPRAVVLLARLSPSGALSEALAAAMTLSVDWFAIAV
                                    :***.:.       :.      **::*****::**  **. * :**.: :

Mflv_3681|M.gilvum_PYR-GCK          LAAWGAVAALCALRWFRFV
Mvan_2729|M.vanbaalenii_PYR-1       LAVWGAVAGLCALRWFRFT
MSMEG_3118|M.smegmatis_MC2_155      LAVWGGVSAVCALRLFRFT
TH_0342|M.thermoresistible__bu      LAVWGVLGAVCALRWFRFT
Rv1457c|M.tuberculosis_H37Rv        LAVWGALAALAALRWFRFT
Mb1492c|M.bovis_AF2122/97           LAVWGALAALAALRWFRFT
MLBr_00589|M.leprae_Br4923          LTAWGTLAALAALHWFRFT
MMAR_2262|M.marinum_M               LAVWGTLAALAARRWFRFT
MUL_1858|M.ulcerans_Agy99           LAVWGTLAALAARRWFRFT
MAV_3322|M.avium_104                LVAWGALGALGALRWFRFT
MAB_2753|M.abscessus_ATCC_1997      LAVWGALAGYGALRWFKFT
                                    *..** :..  * : *:*.