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LTPRAYIATTARILRQLAGDHRSVAMILVVPTLVITLMYFMFAEVPQRPGAPSPFNNACLIMLGVFPLIV MFLITSITMQRERVSGTLERILTTPLRRLDLLAAYGTAFALAAAAQAVFACAVSFWLLGLDTAGSALWVF AIAIVNAVLGVGLGLLCSAFARTEFQAVQFMPLVIAPQLLLCGIVVPRAQLPDWLQWISNALPASYALEA LQEVNAHPELTSVAVRDIAVVLGFTVISLTLAAATLRRRTP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3297 | - | - | 100% (251) | multidrug ABC transporter inner membrane protein |
| M. vanbaalenii PYR-1 | Mvan_3120 | - | 6e-08 | 24.30% (251) | multidrug ABC transporter inner membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1712c | - | 1e-99 | 77.78% (225) | integral membrane protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_3387 | - | 1e-07 | 22.09% (249) | multidrug ABC transporter inner membrane protein |
| M. tuberculosis H37Rv | Rv1686c | - | 1e-100 | 78.22% (225) | integral membrane protein ABC transporter |
| M. leprae Br4923 | MLBr_02350 | - | 9e-07 | 25.24% (210) | putative antibiotic resistance membrane protein |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2485 | - | 1e-100 | 77.88% (226) | antibiotic resistance ABC transporter, efflux protein |
| M. avium 104 | MAV_3086 | - | 1e-104 | 80.70% (228) | ABC transporter efflux protein, DrrB family protein |
| M. smegmatis MC2 155 | MSMEG_3763 | - | 1e-118 | 85.08% (248) | ABC transporter efflux protein, DrrB family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1665 | - | 8e-99 | 76.55% (226) | antibiotic resistance ABC transporter, efflux protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3297|M.vanbaalenii_PYR-1 ------------------------MTPR-----AYIATTARILRQLAGDH
MSMEG_3763|M.smegmatis_MC2_155 ------------------------MSVRRPGSRAYLATTTRILRQLAGDH
MMAR_2485|M.marinum_M --------------------------------------------------
MUL_1665|M.ulcerans_Agy99 --------------------------------------------------
MAV_3086|M.avium_104 --------------------------------------------------
Mb1712c|M.bovis_AF2122/97 --------------------------------------------------
Rv1686c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3387|M.gilvum_PYR-GCK -MTVESSPPASYRVSGKHRRAHVWENSPRQLVPQVAVLTGRILRRWSRDP
MLBr_02350|M.leprae_Br4923 MITMISQTVGLVPASLQYP-----NNSVRALVSQTLLQTKRLLTRWARDY
Mvan_3297|M.vanbaalenii_PYR-1 RSVAMILVVPTLVITLMYFMFAEVPQRPGAPSPFNNACLIMLGVFPLIVM
MSMEG_3763|M.smegmatis_MC2_155 RSVAMILLVPSLIITLIYFMFDDVPQRPGAPSPFNTACLIMLGVFPLIVM
MMAR_2485|M.marinum_M ----MILLVPVLVITLMYFMFENAPHRPGTQTPFNNACLILLGLFPLFVM
MUL_1665|M.ulcerans_Agy99 ----MILLVPVLVITLMYFMFENAPHRPGTQTPFNNACLILLGLFPLVVI
MAV_3086|M.avium_104 --MAMILLVPVLVITLMYFMFENAPHRPGGPTPFNNACLVLLGLFPLFVM
Mb1712c|M.bovis_AF2122/97 ----MILLVPILIITLMYFMFENFPHRPGTPSGFNTACLVLLGLFPLFVM
Rv1686c|M.tuberculosis_H37Rv ----MILLVPILIITLMYFMFENVPHRPGTPSGFNTACLVLLGLFPLFVM
Mflv_3387|M.gilvum_PYR-GCK ATLVQSMVMPAVFLIALDIVLGDVIEAVTGHSGLY-GQVPLVALVGGMTG
MLBr_02350|M.leprae_Br4923 VTIIGALVLPILFLVVLNIVLGNLAYVVTYDSGLY-SFVPLITLGAAITG
:::* :.: : ::: : : : . : :: : ..
Mvan_3297|M.vanbaalenii_PYR-1 FLITSITMQRERVSGTLERILTTPLRRLDLLAAYGTAFALAAAAQAVFAC
MSMEG_3763|M.smegmatis_MC2_155 FLITSITMQRERVSGTLERILTTPLRRFDLLAAYGTAFSLAAAAQATLAC
MMAR_2485|M.marinum_M FIITSITMQRERASGTLERVLTTPLRRLDMLAGYGTAFSLAAAAQATVAC
MUL_1665|M.ulcerans_Agy99 FIITSFTMQRERASGTSERVLTTPLRRLDMLAGYGTAFSLAAAAQATVAC
MAV_3086|M.avium_104 FIITAITMQRERASGTLERILTTPLRRLDLLIAYGTAFSLAAAAQAILAC
Mb1712c|M.bovis_AF2122/97 FVITAITMQRERASGTLERILTTPLRRLDLLAGYGTAFSIAAAAQATLAC
Rv1686c|M.tuberculosis_H37Rv FVITAITMQRERASGTLERILTTPLRRLDLLAGYGTAFSIAAAAQATLAC
Mflv_3387|M.gilvum_PYR-GCK SIIGAVGIMRERDAGLLSRLWVVPVHRAAGLLAR-LAADFIRITAITLVV
MLBr_02350|M.leprae_Br4923 STFVAIDLVRERSIGLLSRLWVLPIHRASGLLAR-ILANTIRTFVTTLVM
: :. : *** * .*: . *::* * . ..
Mvan_3297|M.vanbaalenii_PYR-1 AVSFWLLGLDTAGSALWVFAIAIVNAVLGVGLGLLCS--AFARTEFQAVQ
MSMEG_3763|M.smegmatis_MC2_155 TVAFWLLGFHTEGSPLLVVGIAIVNAVLGVGLGLLCS--AFARTEFQAVQ
MMAR_2485|M.marinum_M IVSFWLLGFDTAGSPVWVFVIAVVNAILGVGLGLLFS--AFARTEFQAVQ
MUL_1665|M.ulcerans_Agy99 IVSFWLLGFDTAGSPVWVFVIAVVNAILGVGLGLLFS--AFARTEFQAVQ
MAV_3086|M.avium_104 IVSFWLLGFDTAGSPVWVFVIAIVNAVLGVGLGLLCS--AFARTEFQAVQ
Mb1712c|M.bovis_AF2122/97 IVAFWFLGFDTAGSPVWVFAIAIVNAVLGVGLGLLCS--AFARTEFQAVQ
Rv1686c|M.tuberculosis_H37Rv IVAFWFLGFDTAGSPVWVFAIAIVNAVLGVGLGLLCS--AFARTEFQAVQ
Mflv_3387|M.gilvum_PYR-GCK MSVGLVLGFRFEQGIPAAIAWVFMPALFGVTLSAAVLTLALLSSSTIAPQ
MLBr_02350|M.leprae_Br4923 LVTGVILGFRFRQGVIASLMWVSVPVIFGIAIAVMVTTVALYTEQTFVVE
.**: . . . : .::*: :. *: . . :
Mvan_3297|M.vanbaalenii_PYR-1 FMPLVIAPQLLLCGIVVPRAQLPDWLQWISNALPASYALEALQEVNAHPE
MSMEG_3763|M.smegmatis_MC2_155 FMPLVIAPQLLLCGIIVPRAALPEWLQWVSNALPASYALEALQEVGAYPD
MMAR_2485|M.marinum_M FIPLVMVPQLLLAGIIVPRAVMPTWLEWVSNAMPASYALEALQQVGAHPE
MUL_1665|M.ulcerans_Agy99 FIPLVMVPQLLLAGIIVPRAVMPTWLEWVSNAMPASYALEALQQVGAHPE
MAV_3086|M.avium_104 FIPLVMVPQLLLAGIIVPRALMPHWLQWISNVLPASYALEALQQVGTHPE
Mb1712c|M.bovis_AF2122/97 FIPLVMVPQLLLAGIIVPRALMPTWLEWISNVMPASYALEALQQVGAHPE
Rv1686c|M.tuberculosis_H37Rv FIPLVMVPQLLLAGIIVPRALMPTWLEWISNVMPASYALEALQQVGAHPE
Mflv_3387|M.gilvum_PYR-GCK ATEILIAILMFFSIGFVPLDQYPEWLQPFVEHQPVSTTIEAMKGLSLEGP
MLBr_02350|M.leprae_Br4923 AVELVQAIAVFLSTGLVPLNQYPGWIQPLVAHQPVSYAIAAMRGLSMGGP
:: . :::. .** * *:: . *.* :: *:: :.
Mvan_3297|M.vanbaalenii_PYR-1 LTSVAVRDIAVVLGFTVISLTLAAATLRRRTP--
MSMEG_3763|M.smegmatis_MC2_155 LTATAVRDISVVVGFAVLALCLAAATLRRRTP--
MMAR_2485|M.marinum_M LTYIALRDIVVVVVFAVASLCLAAATLRRRTP--
MUL_1665|M.ulcerans_Agy99 LTYIALRDIVVVVVFAVASLCLAAATLRRRTP--
MAV_3086|M.avium_104 LTFIAVRDIVVVLGFALAALCLAAATLRRRTP--
Mb1712c|M.bovis_AF2122/97 LTGIAVRDVVVVLSFAVASLCLAAVTLRRRTS--
Rv1686c|M.tuberculosis_H37Rv LTGIAVRDVVVVLSFAVASLCLAAVTLRRRTS--
Mflv_3387|M.gilvum_PYR-GCK IAQPVLFSVLWAAGIAAVCAVPLAIGYRRASKRG
MLBr_02350|M.leprae_Br4923 VLASMVAMLVWTAGICASCAVPLGVGYRRACTH-
: : : . : . . **