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M. ulcerans Agy99 MUL_1665 (-)

annotation: antibiotic resistance ABC transporter, efflux protein
coordinates: 1834434 - 1835114
length: 226

ILLVPVLVITLMYFMFENAPHRPGTQTPFNNACLILLGLFPLVVIFIITSFTMQRERASGTSERVLTTPL
RRLDMLAGYGTAFSLAAAAQATVACIVSFWLLGFDTAGSPVWVFVIAVVNAILGVGLGLLFSAFARTEFQ
AVQFIPLVMVPQLLLAGIIVPRAVMPTWLEWVSNAMPASYALEALQQVGAHPELTYIALRDIVVVVVFAV
ASLCLAAATLRRRTP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1665--100% (226)antibiotic resistance ABC transporter, efflux protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1712c-1e-11085.33% (225) integral membrane protein ABC transporter
M. gilvum PYR-GCKMflv_3681-0.000123.72% (215) multidrug ABC transporter inner membrane protein
M. tuberculosis H37RvRv1686c-1e-11085.33% (225) integral membrane protein ABC transporter
M. leprae Br4923MLBr_02350-6e-0521.36% (220) putative antibiotic resistance membrane protein
M. abscessus ATCC 19977-----
M. marinum MMMAR_2485-1e-12298.23% (226) antibiotic resistance ABC transporter, efflux protein
M. avium 104MAV_3086-1e-11186.73% (226) ABC transporter efflux protein, DrrB family protein
M. smegmatis MC2 155MSMEG_3763-6e-9776.11% (226) ABC transporter efflux protein, DrrB family protein
M. thermoresistible (build 8)-----
M. vanbaalenii PYR-1Mvan_3297-1e-9876.55% (226) multidrug ABC transporter inner membrane protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1712c|M.bovis_AF2122/97           -------------------------------------------------M
Rv1686c|M.tuberculosis_H37Rv        -------------------------------------------------M
MUL_1665|M.ulcerans_Agy99           -------------------------------------------------M
MMAR_2485|M.marinum_M               -------------------------------------------------M
MAV_3086|M.avium_104                -----------------------------------------------MAM
MSMEG_3763|M.smegmatis_MC2_155      -------------------MSVRRPGSRAYLATTTRILRQLAGDHRSVAM
Mvan_3297|M.vanbaalenii_PYR-1       -------------------MTPR-----AYIATTARILRQLAGDHRSVAM
MLBr_02350|M.leprae_Br4923          MITMISQTVGLVPASLQYPNNSVRALVSQTLLQTKRLLTRWARDYVTIIG
Mflv_3681|M.gilvum_PYR-GCK          ------MSVENRFAPGTFTPDPRPAKVPKMLAAQFALELRLLLRN---GE
                                                                                      

Mb1712c|M.bovis_AF2122/97           ILLVPILIITLMYFMFENFPHRPGTPSGFNTACLVLLGLFPLFVMFVITA
Rv1686c|M.tuberculosis_H37Rv        ILLVPILIITLMYFMFENVPHRPGTPSGFNTACLVLLGLFPLFVMFVITA
MUL_1665|M.ulcerans_Agy99           ILLVPVLVITLMYFMFENAPHRPGTQTPFNNACLILLGLFPLVVIFIITS
MMAR_2485|M.marinum_M               ILLVPVLVITLMYFMFENAPHRPGTQTPFNNACLILLGLFPLFVMFIITS
MAV_3086|M.avium_104                ILLVPVLVITLMYFMFENAPHRPGGPTPFNNACLVLLGLFPLFVMFIITA
MSMEG_3763|M.smegmatis_MC2_155      ILLVPSLIITLIYFMFDDVPQRPGAPSPFNTACLIMLGVFPLIVMFLITS
Mvan_3297|M.vanbaalenii_PYR-1       ILVVPTLVITLMYFMFAEVPQRPGAPSPFNNACLIMLGVFPLIVMFLITS
MLBr_02350|M.leprae_Br4923          ALVLPILFLVVLNIVLGNLAYVVTYDSGLY-SFVPLITLGAAITGSTFVA
Mflv_3681|M.gilvum_PYR-GCK          QLLLTMFIPITLLIGLILLPLGSFGPNRAATFVPAIMALAVISTAFTGQA
                                     *::. :.   : : :   .      .        :: :    .     :

Mb1712c|M.bovis_AF2122/97           ITMQRERASGTLERILTTPLRRLDLLAGYGTAFSIAAAAQATLACIVAFW
Rv1686c|M.tuberculosis_H37Rv        ITMQRERASGTLERILTTPLRRLDLLAGYGTAFSIAAAAQATLACIVAFW
MUL_1665|M.ulcerans_Agy99           FTMQRERASGTSERVLTTPLRRLDMLAGYGTAFSLAAAAQATVACIVSFW
MMAR_2485|M.marinum_M               ITMQRERASGTLERVLTTPLRRLDMLAGYGTAFSLAAAAQATVACIVSFW
MAV_3086|M.avium_104                ITMQRERASGTLERILTTPLRRLDLLIAYGTAFSLAAAAQAILACIVSFW
MSMEG_3763|M.smegmatis_MC2_155      ITMQRERVSGTLERILTTPLRRFDLLAAYGTAFSLAAAAQATLACTVAFW
Mvan_3297|M.vanbaalenii_PYR-1       ITMQRERVSGTLERILTTPLRRLDLLAAYGTAFALAAAAQAVFACAVSFW
MLBr_02350|M.leprae_Br4923          IDLVRERSIGLLSRLWVLPIHRASGLLAR-ILANTIRTFVTTLVMLVTGV
Mflv_3681|M.gilvum_PYR-GCK          IAVAFDRRYGALKRLGATALPVWGVIAGKSLAVVTVVSLQSVLFGAIGFA
                                    : :  :*  *  .*: . .:   . : .         :  : .   :   

Mb1712c|M.bovis_AF2122/97           FLGFDTAGSPVWVFAIAIVNAVLGVGLGLLCS--AFARTEFQAVQFIPLV
Rv1686c|M.tuberculosis_H37Rv        FLGFDTAGSPVWVFAIAIVNAVLGVGLGLLCS--AFARTEFQAVQFIPLV
MUL_1665|M.ulcerans_Agy99           LLGFDTAGSPVWVFVIAVVNAILGVGLGLLFS--AFARTEFQAVQFIPLV
MMAR_2485|M.marinum_M               LLGFDTAGSPVWVFVIAVVNAILGVGLGLLFS--AFARTEFQAVQFIPLV
MAV_3086|M.avium_104                LLGFDTAGSPVWVFVIAIVNAVLGVGLGLLCS--AFARTEFQAVQFIPLV
MSMEG_3763|M.smegmatis_MC2_155      LLGFHTEGSPLLVVGIAIVNAVLGVGLGLLCS--AFARTEFQAVQFMPLV
Mvan_3297|M.vanbaalenii_PYR-1       LLGLDTAGSALWVFAIAIVNAVLGVGLGLLCS--AFARTEFQAVQFMPLV
MLBr_02350|M.leprae_Br4923          ILGFRFRQGVIASLMWVSVPVIFGIAIAVMVTTVALYTEQTFVVEAVELV
Mflv_3681|M.gilvum_PYR-GCK          LGWRPPLAGLALGALIIALGTAVFAALGLLLG---GTLRAEIVLALANLL
                                    :       .         : . .  .:.::            .:    *:

Mb1712c|M.bovis_AF2122/97           MVPQLLLAGIIVPRALMPTWLEWISNVMPASYALEALQQVGAHPELTGIA
Rv1686c|M.tuberculosis_H37Rv        MVPQLLLAGIIVPRALMPTWLEWISNVMPASYALEALQQVGAHPELTGIA
MUL_1665|M.ulcerans_Agy99           MVPQLLLAGIIVPRAVMPTWLEWVSNAMPASYALEALQQVGAHPELTYIA
MMAR_2485|M.marinum_M               MVPQLLLAGIIVPRAVMPTWLEWVSNAMPASYALEALQQVGAHPELTYIA
MAV_3086|M.avium_104                MVPQLLLAGIIVPRALMPHWLQWISNVLPASYALEALQQVGTHPELTFIA
MSMEG_3763|M.smegmatis_MC2_155      IAPQLLLCGIIVPRAALPEWLQWVSNALPASYALEALQEVGAYPDLTATA
Mvan_3297|M.vanbaalenii_PYR-1       IAPQLLLCGIVVPRAQLPDWLQWISNALPASYALEALQEVNAHPELTSVA
MLBr_02350|M.leprae_Br4923          QAIAVFLSTGLVPLNQYPGWIQPLVAHQPVSYAIAAMRGLSMGGPVLASM
Mflv_3681|M.gilvum_PYR-GCK          WFVFAGLGALVLERGMVPAAVQWVARLTPSG----ALTEALVQAMTLSVD
                                          *   ::     *  :: :    * .    *:             

Mb1712c|M.bovis_AF2122/97           VRDVVVVLSFAVASLCLAAVTLRRRTS-
Rv1686c|M.tuberculosis_H37Rv        VRDVVVVLSFAVASLCLAAVTLRRRTS-
MUL_1665|M.ulcerans_Agy99           LRDIVVVVVFAVASLCLAAATLRRRTP-
MMAR_2485|M.marinum_M               LRDIVVVVVFAVASLCLAAATLRRRTP-
MAV_3086|M.avium_104                VRDIVVVLGFALAALCLAAATLRRRTP-
MSMEG_3763|M.smegmatis_MC2_155      VRDISVVVGFAVLALCLAAATLRRRTP-
Mvan_3297|M.vanbaalenii_PYR-1       VRDIAVVLGFTVISLTLAAATLRRRTP-
MLBr_02350|M.leprae_Br4923          VAMLVWTAGICASCAVPLGVGYRRACTH
Mflv_3681|M.gilvum_PYR-GCK          WFGLLVLAAWGAVAALCALRWFRFV---
                                       :         .        *