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VAMILLVPVLVITLMYFMFENAPHRPGGPTPFNNACLVLLGLFPLFVMFIITAITMQRERASGTLERILT TPLRRLDLLIAYGTAFSLAAAAQAILACIVSFWLLGFDTAGSPVWVFVIAIVNAVLGVGLGLLCSAFART EFQAVQFIPLVMVPQLLLAGIIVPRALMPHWLQWISNVLPASYALEALQQVGTHPELTFIAVRDIVVVLG FALAALCLAAATLRRRTP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3086 | - | - | 100% (228) | ABC transporter efflux protein, DrrB family protein |
| M. avium 104 | MAV_5182 | - | 2e-06 | 23.26% (172) | ABC-type drug export system, membrane protein |
| M. avium 104 | MAV_3251 | - | 3e-06 | 26.26% (179) | ABC transporter efflux protein, DrrB family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1712c | - | 1e-112 | 88.89% (225) | integral membrane protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_3681 | - | 3e-06 | 25.46% (216) | multidrug ABC transporter inner membrane protein |
| M. tuberculosis H37Rv | Rv1686c | - | 1e-112 | 88.89% (225) | integral membrane protein ABC transporter |
| M. leprae Br4923 | MLBr_02350 | - | 2e-06 | 25.90% (139) | putative antibiotic resistance membrane protein |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2485 | - | 1e-113 | 88.50% (226) | antibiotic resistance ABC transporter, efflux protein |
| M. smegmatis MC2 155 | MSMEG_3763 | - | 1e-101 | 79.39% (228) | ABC transporter efflux protein, DrrB family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1665 | - | 1e-111 | 86.73% (226) | antibiotic resistance ABC transporter, efflux protein |
| M. vanbaalenii PYR-1 | Mvan_3297 | - | 1e-104 | 80.70% (228) | multidrug ABC transporter inner membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1712c|M.bovis_AF2122/97 -------------------------------------------------M
Rv1686c|M.tuberculosis_H37Rv -------------------------------------------------M
MMAR_2485|M.marinum_M -------------------------------------------------M
MUL_1665|M.ulcerans_Agy99 -------------------------------------------------M
MAV_3086|M.avium_104 -----------------------------------------------MAM
MSMEG_3763|M.smegmatis_MC2_155 -------------------MSVRRPGSRAYLATTTRILRQLAGDHRSVAM
Mvan_3297|M.vanbaalenii_PYR-1 -------------------MTPR-----AYIATTARILRQLAGDHRSVAM
MLBr_02350|M.leprae_Br4923 MITMISQTVGLVPASLQYPNNSVRALVSQTLLQTKRLLTRWARDYVTIIG
Mflv_3681|M.gilvum_PYR-GCK ------MSVENRFAPGTFTPDPRPAKVPKMLAAQFALELRLLLRN---GE
Mb1712c|M.bovis_AF2122/97 ILLVPILIITLMYFMFENFPHRPGTPSGFNTACLVLLGLFPLFVMFVITA
Rv1686c|M.tuberculosis_H37Rv ILLVPILIITLMYFMFENVPHRPGTPSGFNTACLVLLGLFPLFVMFVITA
MMAR_2485|M.marinum_M ILLVPVLVITLMYFMFENAPHRPGTQTPFNNACLILLGLFPLFVMFIITS
MUL_1665|M.ulcerans_Agy99 ILLVPVLVITLMYFMFENAPHRPGTQTPFNNACLILLGLFPLVVIFIITS
MAV_3086|M.avium_104 ILLVPVLVITLMYFMFENAPHRPGGPTPFNNACLVLLGLFPLFVMFIITA
MSMEG_3763|M.smegmatis_MC2_155 ILLVPSLIITLIYFMFDDVPQRPGAPSPFNTACLIMLGVFPLIVMFLITS
Mvan_3297|M.vanbaalenii_PYR-1 ILVVPTLVITLMYFMFAEVPQRPGAPSPFNNACLIMLGVFPLIVMFLITS
MLBr_02350|M.leprae_Br4923 ALVLPILFLVVLNIVLGNLAYVVTYDSGLY-SFVPLITLGAAITGSTFVA
Mflv_3681|M.gilvum_PYR-GCK QLLLTMFIPITLLIGLILLPLGSFGPNRAATFVPAIMALAVISTAFTGQA
*::. :. : : : . . :: : . :
Mb1712c|M.bovis_AF2122/97 ITMQRERASGTLERILTTPLRRLDLLAGYGTAFSIAAAAQATLACIVAFW
Rv1686c|M.tuberculosis_H37Rv ITMQRERASGTLERILTTPLRRLDLLAGYGTAFSIAAAAQATLACIVAFW
MMAR_2485|M.marinum_M ITMQRERASGTLERVLTTPLRRLDMLAGYGTAFSLAAAAQATVACIVSFW
MUL_1665|M.ulcerans_Agy99 FTMQRERASGTSERVLTTPLRRLDMLAGYGTAFSLAAAAQATVACIVSFW
MAV_3086|M.avium_104 ITMQRERASGTLERILTTPLRRLDLLIAYGTAFSLAAAAQAILACIVSFW
MSMEG_3763|M.smegmatis_MC2_155 ITMQRERVSGTLERILTTPLRRFDLLAAYGTAFSLAAAAQATLACTVAFW
Mvan_3297|M.vanbaalenii_PYR-1 ITMQRERVSGTLERILTTPLRRLDLLAAYGTAFALAAAAQAVFACAVSFW
MLBr_02350|M.leprae_Br4923 IDLVRERSIGLLSRLWVLPIHRASGLLAR-ILANTIRTFVTTLVMLVTGV
Mflv_3681|M.gilvum_PYR-GCK IAVAFDRRYGALKRLGATALPVWGVIAGKSLAVVTVVSLQSVLFGAIGFA
: : :* * .*: . .: . : . : : . :
Mb1712c|M.bovis_AF2122/97 FLGFDTAGSPVWVFAIAIVNAVLGVGLGLLCS--AFARTEFQAVQFIPLV
Rv1686c|M.tuberculosis_H37Rv FLGFDTAGSPVWVFAIAIVNAVLGVGLGLLCS--AFARTEFQAVQFIPLV
MMAR_2485|M.marinum_M LLGFDTAGSPVWVFVIAVVNAILGVGLGLLFS--AFARTEFQAVQFIPLV
MUL_1665|M.ulcerans_Agy99 LLGFDTAGSPVWVFVIAVVNAILGVGLGLLFS--AFARTEFQAVQFIPLV
MAV_3086|M.avium_104 LLGFDTAGSPVWVFVIAIVNAVLGVGLGLLCS--AFARTEFQAVQFIPLV
MSMEG_3763|M.smegmatis_MC2_155 LLGFHTEGSPLLVVGIAIVNAVLGVGLGLLCS--AFARTEFQAVQFMPLV
Mvan_3297|M.vanbaalenii_PYR-1 LLGLDTAGSALWVFAIAIVNAVLGVGLGLLCS--AFARTEFQAVQFMPLV
MLBr_02350|M.leprae_Br4923 ILGFRFRQGVIASLMWVSVPVIFGIAIAVMVTTVALYTEQTFVVEAVELV
Mflv_3681|M.gilvum_PYR-GCK LGWRPPLAGLALGALIIALGTAVFAALGLLLG---GTLRAEIVLALANLL
: . : . . .:.:: .: *:
Mb1712c|M.bovis_AF2122/97 MVPQLLLAGIIVPRALMPTWLEWISNVMPASYALEALQQVGAHPELTGIA
Rv1686c|M.tuberculosis_H37Rv MVPQLLLAGIIVPRALMPTWLEWISNVMPASYALEALQQVGAHPELTGIA
MMAR_2485|M.marinum_M MVPQLLLAGIIVPRAVMPTWLEWVSNAMPASYALEALQQVGAHPELTYIA
MUL_1665|M.ulcerans_Agy99 MVPQLLLAGIIVPRAVMPTWLEWVSNAMPASYALEALQQVGAHPELTYIA
MAV_3086|M.avium_104 MVPQLLLAGIIVPRALMPHWLQWISNVLPASYALEALQQVGTHPELTFIA
MSMEG_3763|M.smegmatis_MC2_155 IAPQLLLCGIIVPRAALPEWLQWVSNALPASYALEALQEVGAYPDLTATA
Mvan_3297|M.vanbaalenii_PYR-1 IAPQLLLCGIVVPRAQLPDWLQWISNALPASYALEALQEVNAHPELTSVA
MLBr_02350|M.leprae_Br4923 QAIAVFLSTGLVPLNQYPGWIQPLVAHQPVSYAIAAMRGLSMGGPVLASM
Mflv_3681|M.gilvum_PYR-GCK WFVFAGLGALVLERGMVPAAVQWVARLTPSG----ALTEALVQAMTLSVD
* :: * :: : * . *:
Mb1712c|M.bovis_AF2122/97 VRDVVVVLSFAVASLCLAAVTLRRRTS-
Rv1686c|M.tuberculosis_H37Rv VRDVVVVLSFAVASLCLAAVTLRRRTS-
MMAR_2485|M.marinum_M LRDIVVVVVFAVASLCLAAATLRRRTP-
MUL_1665|M.ulcerans_Agy99 LRDIVVVVVFAVASLCLAAATLRRRTP-
MAV_3086|M.avium_104 VRDIVVVLGFALAALCLAAATLRRRTP-
MSMEG_3763|M.smegmatis_MC2_155 VRDISVVVGFAVLALCLAAATLRRRTP-
Mvan_3297|M.vanbaalenii_PYR-1 VRDIAVVLGFTVISLTLAAATLRRRTP-
MLBr_02350|M.leprae_Br4923 VAMLVWTAGICASCAVPLGVGYRRACTH
Mflv_3681|M.gilvum_PYR-GCK WFGLLVLAAWGAVAALCALRWFRFV---
: . *