For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VLPQRPNCTKLFRPRRGVSERYRVTTAHNGSAPRFQRTRSGYDPVAVNHYIAELVLRQQAQHCEIETLKA EIASLKDENAALKDTSPSAQAVTDRMAKMLRLAVDEVFQMQSEARAEAATLVSAARDEAEAVRTQKREML ADMNARQRALESEHADVMRRAREEAEQLVAQATAEVERMRVIDARRREKAEQELDAEIIRLRTDAQFQID DQLQATQQECEKRLGEAKIEADRRLHVADEQIEHGLSEARRTLEEISQRRVGILEQLARIHAQLENIPAL LESARHSETEPLQSINGAVAELRAI
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv1682 | - | - | 100% (305) | Probable coiled-coil structural protein |
M. tuberculosis H37Rv | Rv2927c | - | 4e-06 | 23.88% (134) | hypothetical protein Rv2927c |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1709 | - | 1e-167 | 100.00% (305) | coiled-coil structural protein |
M. gilvum PYR-GCK | Mflv_4194 | - | 2e-07 | 28.43% (197) | hypothetical protein Mflv_4194 |
M. leprae Br4923 | MLBr_01661 | - | 5e-07 | 26.92% (208) | hypothetical protein MLBr_01661 |
M. abscessus ATCC 19977 | MAB_1531c | - | 6e-82 | 58.05% (267) | hypothetical protein MAB_1531c |
M. marinum M | MMAR_1785 | smc | 3e-06 | 27.56% (254) | chromosome partition protein Smc |
M. avium 104 | MAV_3650 | - | 5e-39 | 40.08% (257) | hypothetical protein MAV_3650 |
M. smegmatis MC2 155 | MSMEG_1517 | - | 4e-09 | 27.32% (194) | SPFH domain-containing protein/band 7 family protein |
M. thermoresistible (build 8) | TH_1226 | - | 1e-08 | 27.84% (194) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_2033 | smc | 2e-06 | 27.56% (254) | chromosome partition protein Smc |
M. vanbaalenii PYR-1 | Mvan_1428 | - | 2e-09 | 26.95% (256) | band 7 protein |
CLUSTAL 2.0.9 multiple sequence alignment Rv1682|M.tuberculosis_H37Rv -------------------------------------------------- Mb1709|M.bovis_AF2122/97 -------------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4194|M.gilvum_PYR-GCK -------------------------------------------------- TH_1226|M.thermoresistible__bu -------------------------------------------------- MLBr_01661|M.leprae_Br4923 -------------------------------------------------- MMAR_1785|M.marinum_M MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE MUL_2033|M.ulcerans_Agy99 MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE Rv1682|M.tuberculosis_H37Rv -------------------------------------------------- Mb1709|M.bovis_AF2122/97 -------------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4194|M.gilvum_PYR-GCK -------------------------------------------------- TH_1226|M.thermoresistible__bu -------------------------------------------------- MLBr_01661|M.leprae_Br4923 -------------------------------------------------- MMAR_1785|M.marinum_M QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVTIDNSDNALPIEYTEVSI MUL_2033|M.ulcerans_Agy99 QGAKTLRGGKMEDVIFAGTSLRAPLGRAEVTVTIDNSDNALPIEYTEVSI Rv1682|M.tuberculosis_H37Rv -------------------------------------------------- Mb1709|M.bovis_AF2122/97 -------------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4194|M.gilvum_PYR-GCK -------------------------------------------------- TH_1226|M.thermoresistible__bu -------------------------------------------------- MLBr_01661|M.leprae_Br4923 -------------------------------------------------- MMAR_1785|M.marinum_M TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEIL MUL_2033|M.ulcerans_Agy99 TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEIL Rv1682|M.tuberculosis_H37Rv -------------------------------------------------- Mb1709|M.bovis_AF2122/97 -------------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4194|M.gilvum_PYR-GCK -------------------------------------------------- TH_1226|M.thermoresistible__bu -------------------------------------------------- MLBr_01661|M.leprae_Br4923 -------------------------------------------------- MMAR_1785|M.marinum_M QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELRR MUL_2033|M.ulcerans_Agy99 QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELRR Rv1682|M.tuberculosis_H37Rv -------------------------------------------------- Mb1709|M.bovis_AF2122/97 -------------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4194|M.gilvum_PYR-GCK -------------------------------------------------- TH_1226|M.thermoresistible__bu -------------------------------------------------- MLBr_01661|M.leprae_Br4923 -------------------------------------------------- MMAR_1785|M.marinum_M QLKPLGRQAEVARRAQTIQADLRDARLRLAADDVVSRRAEREAIFEAEAT MUL_2033|M.ulcerans_Agy99 QLKPLGRQAEVARRAQTIQADLRDARLRLAADDVVSRRAEREAIFEAEAT Rv1682|M.tuberculosis_H37Rv -------------------------------------------------- Mb1709|M.bovis_AF2122/97 -------------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4194|M.gilvum_PYR-GCK -------------------------------------------------- TH_1226|M.thermoresistible__bu -------------------------------------------------- MLBr_01661|M.leprae_Br4923 -------------------------------------------------- MMAR_1785|M.marinum_M MRREHDEAAARLTVAAEELAAHEAALAELTSRAESVQHTWFGLSALAERV MUL_2033|M.ulcerans_Agy99 MRREHDEAAARLTVAAEELAAHEATLAELTSRAESVQHTWFGLSALAERV Rv1682|M.tuberculosis_H37Rv -------------------------------------------------- Mb1709|M.bovis_AF2122/97 -------------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4194|M.gilvum_PYR-GCK -------------------------------------------------- TH_1226|M.thermoresistible__bu -------------------------------------------------- MLBr_01661|M.leprae_Br4923 -------------------------------------------------- MMAR_1785|M.marinum_M GTTVRIANERAQHLDVEPVTNSDTDPDALDAEAEQVAIAEQQLLVELAEA MUL_2033|M.ulcerans_Agy99 GTTVRIANERAQHLDVEPVTNSDTDPDALDAEAEQVAIAEQQLLVELAEA Rv1682|M.tuberculosis_H37Rv -------------------------------------------------- Mb1709|M.bovis_AF2122/97 -------------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4194|M.gilvum_PYR-GCK -------------------------------------------------- TH_1226|M.thermoresistible__bu -------------------------------------------------- MLBr_01661|M.leprae_Br4923 -------------------------------------------------- MMAR_1785|M.marinum_M RDRLDAARAELADREHRAAEADRAHLAAVRAEADRREGLARLAGQVETMR MUL_2033|M.ulcerans_Agy99 RDRLDAARAELADREHRAAEADRAHLAAVRAEADRREGLARLAGQVETMR Rv1682|M.tuberculosis_H37Rv -------------------------------------------------- Mb1709|M.bovis_AF2122/97 -------------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4194|M.gilvum_PYR-GCK -------------------------------------------------- TH_1226|M.thermoresistible__bu -------------------------------------------------- MLBr_01661|M.leprae_Br4923 -------------------------------------------------- MMAR_1785|M.marinum_M ARVESIDDSVARLSERIEHAAARAQQTRAEFETVQARVGELDQGEVGLDE MUL_2033|M.ulcerans_Agy99 ARVESIDDSVARLSERIEHAAARAQQTRAEFETVQARVGELDQGEVGLDE Rv1682|M.tuberculosis_H37Rv -------------------------------------------------- Mb1709|M.bovis_AF2122/97 -------------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4194|M.gilvum_PYR-GCK -------------------------------------------------- TH_1226|M.thermoresistible__bu -------------------------------------------------- MLBr_01661|M.leprae_Br4923 -------------------------------------------------- MMAR_1785|M.marinum_M QHERTVAALRLAEQRLAELQVAERDAERQVASLRARIEALSVGLDRKDGA MUL_2033|M.ulcerans_Agy99 QHERTVAALRLAEQRLAELQVAERDAERQVASLRARIGALSVGLDRKDGA Rv1682|M.tuberculosis_H37Rv -------------------------------------------------- Mb1709|M.bovis_AF2122/97 -------------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4194|M.gilvum_PYR-GCK -------------------------------------------------- TH_1226|M.thermoresistible__bu -------------------------------------------------- MLBr_01661|M.leprae_Br4923 -------------------------------------------------- MMAR_1785|M.marinum_M AWLARNHSDAGLFGSVAQLVKVRSGYEAAVAAVLGSAAEALAADSFGAAR MUL_2033|M.ulcerans_Agy99 AWLARNHSDAGLFGSVAQLVKVRSGYEAAVAAVLGSAAEALAADSFGAAR Rv1682|M.tuberculosis_H37Rv -------------------------------------------------- Mb1709|M.bovis_AF2122/97 -------------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4194|M.gilvum_PYR-GCK -------------------------------------------------- TH_1226|M.thermoresistible__bu -------------------------------------------------- MLBr_01661|M.leprae_Br4923 -------------------------------------------------- MMAR_1785|M.marinum_M SAVTALKQADGGRAALVLGDWPDANDHRAAGGLPSGTLWALDLIEVPSRL MUL_2033|M.ulcerans_Agy99 SAVTALKQADGGRAALVLGDWPDAHDHRAAGGLPSGTLWALDLIEVPSRL Rv1682|M.tuberculosis_H37Rv -------------------------------------------------- Mb1709|M.bovis_AF2122/97 -------------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 ------------------------------------MSTLLIVVLAAIAA Mvan_1428|M.vanbaalenii_PYR-1 ------------------------------------MSVLLITVIAGIAA Mflv_4194|M.gilvum_PYR-GCK -------------------------------------------------- TH_1226|M.thermoresistible__bu -------------------------------------------------- MLBr_01661|M.leprae_Br4923 -------------------------------------------------- MMAR_1785|M.marinum_M RPAMTAMLSGVVVVNDLSEALDLVQAQPQLRAVTLDGDLVGAGWVSGGSD MUL_2033|M.ulcerans_Agy99 RPAMTAMLSGVVVVNDLSEALDLVQAQPQLRAVTLDGDLVGAGWVSGGSD Rv1682|M.tuberculosis_H37Rv -------------------------------------------------- Mb1709|M.bovis_AF2122/97 -------------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 ILILVVVPLIYVKNYIKVPPNEVAVFTGRGAPKVVRGGARFRMPGIERVD Mvan_1428|M.vanbaalenii_PYR-1 LLLFVALPIVYVKNYIKVPPNEVAVFTGRGQPKVVRGGARFRVPGIERVD Mflv_4194|M.gilvum_PYR-GCK -------------------------------------------------- TH_1226|M.thermoresistible__bu -------------------------------------------------- MLBr_01661|M.leprae_Br4923 -------------------------------------------------- MMAR_1785|M.marinum_M RKPSTLEITSEIDKARSELAAAEVRVAELGAALSGALTDQTARQDAAEQA MUL_2033|M.ulcerans_Agy99 RKPSTLEITSEIDKARRELAAAEVRVAELGAALSGALTDQTARQDAAEQA Rv1682|M.tuberculosis_H37Rv ---------MLPQRPNCTKLFRPRRGVSERYRVTTAHNGSAPRFQRTRSG Mb1709|M.bovis_AF2122/97 ---------MLPQRPNCTKLFRPRRGVSERYRVTTAHNGSAPRFQRTRSG MAB_1531c|M.abscessus_ATCC_199 -------------------------------MTTTTLNESTRNFTRTRNG MAV_3650|M.avium_104 -----------------------------------MITEPVKTFSRKFMG MSMEG_1517|M.smegmatis_MC2_155 IMSLEPFNVSINLQNALSNNGVPVNVEAVGLVRIGSADEAVQTAVQRFLT Mvan_1428|M.vanbaalenii_PYR-1 IMSLEPFNVSINLQNALSNNGVPVNVEAVGLVRIGSADEAVQTAVQRFLT Mflv_4194|M.gilvum_PYR-GCK -------MYRVFEALDELGAIVEEAR------------GVPMTAGCVVPR TH_1226|M.thermoresistible__bu -----------------------------------------MTAGCVVPR MLBr_01661|M.leprae_Br4923 -----MAVYRVFEALDELGAIVEEAR------------GVPMTAGCVVPR MMAR_1785|M.marinum_M LAALNESDTAISAMYEQLGRIGQDARGAEEEWTRLLRQREELEVGRTQTL MUL_2033|M.ulcerans_Agy99 LAALNESDTAISAMYEQLGRIGQDARGAEEEWTRLLRQREELEVGRTQTL Rv1682|M.tuberculosis_H37Rv YDPVAVNHYIAELVLRQQAQHCEIETLKA-------EIASLKDEN----- Mb1709|M.bovis_AF2122/97 YDPVAVNHYIAELVLRQQAQHCEIETLKA-------EIASLKDEN----- MAB_1531c|M.abscessus_ATCC_199 YDPIEVNEYISRLTIMHQSGLNDVETLKSRLEDATKQISSLKDEV----- MAV_3650|M.avium_104 YDTTAVDAHIEMLTAKQQLLIDDVESLRARLQESNEQTAALRKEV----- MSMEG_1517|M.smegmatis_MC2_155 SDLNELQRQINEILAGSLRGITATMTVEDLNSNRDTLARSVVEEAGADLA Mvan_1428|M.vanbaalenii_PYR-1 SDLNELQRQINEILAGSLRGITATMTVEDLNSNRDTLARSVVDEAGGDLA Mflv_4194|M.gilvum_PYR-GCK GDVLELIDDIKDAIPGELDDAQDVLDAR---------------------- TH_1226|M.thermoresistible__bu GDVLELIDDIKDAIPGELDDAQDVLDAR---------------------- MLBr_01661|M.leprae_Br4923 GDVLELIDDIKDAIPGELDDAQDVLDAR---------------------- MMAR_1785|M.marinum_M EEVLELESRLRNAQESQHVQAAEPVDRQEIAAAAESARAIEVEAR----- MUL_2033|M.ulcerans_Agy99 EEVLELESRLRNAQESQHVQAAEPVDRQEIAAAAESARAIEVEAR----- : : : . Rv1682|M.tuberculosis_H37Rv -----------AALKDTSPSAQAVTDR-MAKMLRLAVDEVFQMQ------ Mb1709|M.bovis_AF2122/97 -----------AALKDTSPSAQAVTDR-MAKMLRLAVDEVFQMQ------ MAB_1531c|M.abscessus_ATCC_199 -----------TTLSDTSPSAHAMTDR-MAKMLRIAVDEVAEMQ------ MAV_3650|M.avium_104 -----------AALTDTSPAPHAVQQR-MAKMLARAVDEVAEMQ------ MSMEG_1517|M.smegmatis_MC2_155 RIGMEVDVLKIAGISDRNGYLESLGQRRIAEVKRDATVGTAEAERDAQIQ Mvan_1428|M.vanbaalenii_PYR-1 RIGMEVDVLKIAGISDRNGYLESLGQRRIAEVKRDAAVGTAEAERDAQIQ Mflv_4194|M.gilvum_PYR-GCK ----------DAMLREAKDHAESTVSTANAEADS---------------M TH_1226|M.thermoresistible__bu ----------DTLLREAKEHSESMVSTATAEAES---------------L MLBr_01661|M.leprae_Br4923 ----------DAMLNDAKAHADSMVSSATTESES---------------L MMAR_1785|M.marinum_M ----LTVRTAEERANALRGRADSLRRAAAAEREARVRAELARAVRLRSAA MUL_2033|M.ulcerans_Agy99 ----LTVRTAEERANALRGRADSLRRVAAAEREARVRAELARAVRLRSAA .: :: Rv1682|M.tuberculosis_H37Rv -SEARAEAATLVSAARDEAEAVRTQKREMLADMNARQRALESEHADVMRR Mb1709|M.bovis_AF2122/97 -SEARAEAATLVSAARDEAEAVRTQKREMLADMNARQRALESEHADVMRR MAB_1531c|M.abscessus_ATCC_199 -NEARTESAALIASAKADAEAMRTKHKELLADMAARQSALETEYTEVMAR MAV_3650|M.avium_104 -AEARAEADALIAAAEAEAQAAERKRDEVLADMAAQQEALEAEYRETK-- MSMEG_1517|M.smegmatis_MC2_155 SAKARQEGSIAQAEADTAIASANQKRDVELARLRAQTEAENAQADQAGPL Mvan_1428|M.vanbaalenii_PYR-1 SAKARQAGAVAQAEADTAIATANQKRDVELARLRAQTEAENAQADQAGPL Mflv_4194|M.gilvum_PYR-GCK VNHARTEADRLLA-------DAKAQADRMVAEARQHSERMVGEAREEA-- TH_1226|M.thermoresistible__bu VSHARAEADRLLA-------EAKAQADRMVAEARQHSERMVTEAREEA-- MLBr_01661|M.leprae_Br4923 LSHARAEADRILS-------DAKSQVDRMASEARQHSERMLGDAREES-- MMAR_1785|M.marinum_M VAAAVAESGRLLAWRLNRVVDAASQLRDELAAERQQRSAAMSAVREETSS MUL_2033|M.ulcerans_Agy99 VAAAVAESGRLLAWRLNRVVDAASQLRDELAAERQQRSAAMSAVREETSS * . : : : : : Rv1682|M.tuberculosis_H37Rv AREEAEQLVAQATAEVERMRVID--------------------------- Mb1709|M.bovis_AF2122/97 AREEAEQLVAQATAEVERMRVID--------------------------- MAB_1531c|M.abscessus_ATCC_199 AREEANQIVAQAVSESERLRAAE--------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 ANARAQKDVGIAIEQAEAARVQAR-------------------------- Mvan_1428|M.vanbaalenii_PYR-1 ANARAQKDVGIAIEQAEAARVQAR-------------------------- Mflv_4194|M.gilvum_PYR-GCK --ARIAATAKREYEASTG-------------------------------- TH_1226|M.thermoresistible__bu --SRIVATAKREYEATTG-------------------------------- MLBr_01661|M.leprae_Br4923 --IRIATVAKREYEASLN-------------------------------- MMAR_1785|M.marinum_M LSARVATLTDSLHRDEVANAQAALRIEQVEQMVLEQFGMAPSDLVAEYGP MUL_2033|M.ulcerans_Agy99 LSARVATLTDSLHRDEVANAQAALRIEQVEQMVLEQFGMAPSDLVAEYGP Rv1682|M.tuberculosis_H37Rv --------------ARRREKAEQELDAEIIRLRTDAQFQIDDQLQATQQE Mb1709|M.bovis_AF2122/97 --------------ARRREKAEQELDAEIIRLRTDAQFQIDDQLQATQQE MAB_1531c|M.abscessus_ATCC_199 --------------AKRREKAETELDEELTKLRTDTQSAVDEQRRSIQGE MAV_3650|M.avium_104 ----------------------EKLDAELADMRAEAQAAIDEARRAAERE MSMEG_1517|M.smegmatis_MC2_155 ----------IEVEQRRSEQAQAALQADVIAP-AEAQRQADVARAEGQRQ Mvan_1428|M.vanbaalenii_PYR-1 ----------IEVEQRRAEQSQAALQADVIAP-AEAQRAADIARAEGQRQ Mflv_4194|M.gilvum_PYR-GCK ---------------RAKSEADRLLESGNLAYEKAVQEG-IKEQQRLVSQ TH_1226|M.thermoresistible__bu ---------------RAKSEADRLIESGNLAYEKAVQEG-IKEQQRLVSQ MLBr_01661|M.leprae_Br4923 ---------------RAQSECDRLIENGNISYEKAIQEG-IKEQQRLVSQ MMAR_1785|M.marinum_M DVALPPTELEMAEFEQARERGEQVVAPAPMPFDRATQQRRAKRAERELTE MUL_2033|M.ulcerans_Agy99 DVALPPTELEMAEFEQARERGEQVVAPAPMPFDRATQQRRAKRAERELTE : * : Rv1682|M.tuberculosis_H37Rv CEKRLG---------EAKIEADRRLHVADEQIEHGLSEAR---------- Mb1709|M.bovis_AF2122/97 CEKRLG---------EAKIEADRRLHVADEQIEHGLSEAR---------- MAB_1531c|M.abscessus_ATCC_199 CEKRLA---------DAKDEADRRLRLADEQIERRLDQAR---------- MAV_3650|M.avium_104 CEQLLG---------DAKQGAD-----------HYRDTAR---------- MSMEG_1517|M.smegmatis_MC2_155 AAILAAEAAAEAKRRAGQAEADARKAAADALRVERQAEADSLQANLVAEA Mvan_1428|M.vanbaalenii_PYR-1 ATILA-----------GQAEADARKAAADALRVERQAEAD---------- Mflv_4194|M.gilvum_PYR-GCK TEVVAT----------ATAEATRMIDS----------------------- TH_1226|M.thermoresistible__bu TEIVQT----------ANAEASRLIDS----------------------- MLBr_01661|M.leprae_Br4923 NEVVQA----------ANAESTRLIDT----------------------- MMAR_1785|M.marinum_M LGRVNP----------LALEEFAALEERYNFLSTQLEDVKAARKDL---- MUL_2033|M.ulcerans_Agy99 LGRVNP----------LALEEFAALEERYNFLSTQLEDVKAARKDL---- Rv1682|M.tuberculosis_H37Rv -----------------------RTLEEISQRR--VGILEQLAR------ Mb1709|M.bovis_AF2122/97 -----------------------RTLEEISQRR--VGILEQLAR------ MAB_1531c|M.abscessus_ATCC_199 -----------------------RSVEEIGQQR--ISILEQLMG------ MAV_3650|M.avium_104 -----------------------RAVEEASAQR--IKILEQLMS------ MSMEG_1517|M.smegmatis_MC2_155 AGKKELADALRVEQQAEAAGIEARLLAEANGKKEIAAALNSYTA------ Mvan_1428|M.vanbaalenii_PYR-1 -------------------GIKARLVAEAAGKKEIAAALNTYSP------ Mflv_4194|M.gilvum_PYR-GCK ------------------------AHAEADRLRGECDIYVDSK------- TH_1226|M.thermoresistible__bu ------------------------AHAEADRLRGECDIYVDSK------- MLBr_01661|M.leprae_Br4923 ------------------------AHAEADRLRGECDIYVDNK------- MMAR_1785|M.marinum_M --------------------LDVVADVDARILQVFSDAFVDVEREFQIVF MUL_2033|M.ulcerans_Agy99 --------------------LDVVADVDARILQVFSDAFVDVEREFQIVF : : Rv1682|M.tuberculosis_H37Rv --------IHAQLENIPALLESAR---HSETEPLQSING-AVAELRAI-- Mb1709|M.bovis_AF2122/97 --------IHAQLENIPALLESAR---HSETEPLQSING-AVAELRAI-- MAB_1531c|M.abscessus_ATCC_199 --------VHGRLESIPSALESAYRD-RDNSKSIVMVPSKRVLDQKVIEG MAV_3650|M.avium_104 --------VYRELEDVPAALQAAY----DEQQGSADDGVLAAVDGKVRAG MSMEG_1517|M.smegmatis_MC2_155 --------EAARMLMLPDVLNSVVKATEAAASPLGEIERLSIIGGAGDAQ Mvan_1428|M.vanbaalenii_PYR-1 --------EAARLQTLPDVLQSVVKATEAAAMPLSEIERLSIIGGASDAQ Mflv_4194|M.gilvum_PYR-GCK ------------LAEFEDFLNG------TLRSVGRGRHQLRTSAGTHDYA TH_1226|M.thermoresistible__bu ------------LAEFEEFLNG------TLRSVNRGRHQLRTAAGTHDYV MLBr_01661|M.leprae_Br4923 ------------LAEFEEFLNG------TLRSVGRGRHQLRTAAGTHDYV MMAR_1785|M.marinum_M SSLFPGGEGRLRLTAPEDMLTTGIEV--EARPPGKKVSRLSLLSGGEKAL MUL_2033|M.ulcerans_Agy99 SSLFPGGEGRLRLTAPEDMLTTGIEV--EARPPGKKVSRLSLLSGGEKAL : * Rv1682|M.tuberculosis_H37Rv -------------------------------------------------- Mb1709|M.bovis_AF2122/97 -------------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_3650|M.avium_104 -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 DAVGGLLGISPLAVAKIIESLKSSGVDVAALLGGSGASTGPNGSNVSTPP Mvan_1428|M.vanbaalenii_PYR-1 DAVGGLLGVSPLAVAKIVETLKSSGIDVAAMLN-------PSPEPPIAPA Mflv_4194|M.gilvum_PYR-GCK AR------------------------------------------------ TH_1226|M.thermoresistible__bu TR------------------------------------------------ MLBr_01661|M.leprae_Br4923 TR------------------------------------------------ MMAR_1785|M.marinum_M TAVAMLVAIFRARPSPFYIMDEVEAALDDTNLRRLIGLFEMLRDRSQLII MUL_2033|M.ulcerans_Agy99 TAVAILVAIFRARPSPFYIMDEVEAALDDTNLRRLIGLFEMLRDRSQLII Rv1682|M.tuberculosis_H37Rv --------------------------------------------- Mb1709|M.bovis_AF2122/97 --------------------------------------------- MAB_1531c|M.abscessus_ATCC_199 --------------------------------------------- MAV_3650|M.avium_104 --------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 ATNGDIAATAPAE-------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 EANGEGAAQPL---------------------------------- Mflv_4194|M.gilvum_PYR-GCK --------------------------------------------- TH_1226|M.thermoresistible__bu --------------------------------------------- MLBr_01661|M.leprae_Br4923 --------------------------------------------- MMAR_1785|M.marinum_M ITHQKPTMEVADALYGVTMQGDGITAVISQRIRGQQVDRLVANSS MUL_2033|M.ulcerans_Agy99 ITHQKPTMEVADALYGVTMQGDGITAVISQRIRGQQVDRLVANSS