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STLLIVVLAAIAAILILVVVPLIYVKNYIKVPPNEVAVFTGRGAPKVVRGGARFRMPGIERVDIMSLEPF NVSINLQNALSNNGVPVNVEAVGLVRIGSADEAVQTAVQRFLTSDLNELQRQINEILAGSLRGITATMTV EDLNSNRDTLARSVVEEAGADLARIGMEVDVLKIAGISDRNGYLESLGQRRIAEVKRDATVGTAEAERDA QIQSAKARQEGSIAQAEADTAIASANQKRDVELARLRAQTEAENAQADQAGPLANARAQKDVGIAIEQAE AARVQARIEVEQRRSEQAQAALQADVIAPAEAQRQADVARAEGQRQAAILAAEAAAEAKRRAGQAEADAR KAAADALRVERQAEADSLQANLVAEAAGKKELADALRVEQQAEAAGIEARLLAEANGKKEIAAALNSYTA EAARMLMLPDVLNSVVKATEAAASPLGEIERLSIIGGAGDAQDAVGGLLGISPLAVAKIIESLKSSGVDV AALLGGSGASTGPNGSNVSTPPATNGDIAATAPAE*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_1517 | - | - | 100% (526) | SPFH domain-containing protein/band 7 family protein |
M. smegmatis MC2 155 | MSMEG_3155 | - | 8e-12 | 24.62% (260) | band 7 protein |
M. smegmatis MC2 155 | MSMEG_2423 | smc | 9e-08 | 24.09% (386) | chromosome segregation protein SMC |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1524 | - | 1e-10 | 22.26% (310) | hypothetical protein Mb1524 |
M. gilvum PYR-GCK | Mflv_3597 | - | 1e-11 | 26.48% (355) | prolipoprotein diacylglyceryl transferase |
M. tuberculosis H37Rv | Rv1488 | - | 1e-10 | 22.26% (310) | hypothetical protein Rv1488 |
M. leprae Br4923 | MLBr_01802 | - | 4e-09 | 23.17% (259) | hypothetical protein MLBr_01802 |
M. abscessus ATCC 19977 | MAB_3777 | - | 0.0 | 79.96% (504) | Band 7 protein |
M. marinum M | MMAR_5349 | - | 1e-32 | 32.61% (322) | hypothetical protein MMAR_5349 |
M. avium 104 | MAV_3777 | smc | 2e-09 | 23.84% (453) | chromosome segregation protein SMC |
M. thermoresistible (build 8) | TH_1418 | - | 1e-11 | 21.48% (256) | POSSIBLE EXPORTED CONSERVED PROTEIN |
M. ulcerans Agy99 | MUL_2033 | smc | 5e-07 | 24.71% (344) | chromosome partition protein Smc |
M. vanbaalenii PYR-1 | Mvan_1428 | - | 0.0 | 79.85% (521) | band 7 protein |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_1517|M.smegmatis_MC2_155 --MSTLLIVVLAAIAAILILVVVPLIYVKNYIKVPP-----NEVAVFTGR Mvan_1428|M.vanbaalenii_PYR-1 --MSVLLITVIAGIAALLLFVALPIVYVKNYIKVPP-----NEVAVFTGR MAB_3777|M.abscessus_ATCC_1997 --MSSLVIIVIIAIAALVLFVALPLIYVRNYVKVPP-----NEVAVFTGR MAV_3777|M.avium_104 MYLKSLTLKGFKSFASPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE MUL_2033|M.ulcerans_Agy99 MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE Mb1524|M.bovis_AF2122/97 ------MQGAVAGLVFLAVLVIFAIIVVAKSVALIP----QAEAAVIERL Rv1488|M.tuberculosis_H37Rv ------MQGAVAGLVFLAVLVIFAIIVVAKSVALIP----QAEAAVIERL MLBr_01802|M.leprae_Br4923 ------MQGVVAGLVLLAVLTIFAIVVVAKSIVLIP----QAEAAVVERL TH_1418|M.thermoresistible__bu ------MDGAVAGLVILIVLVVFAAILVAKSVALIP----QAEAAVIERL MMAR_5349|M.marinum_M -------------MLGYKVPDPDEAMLISGGRVKGN-----APFRVVTGH Mflv_3597|M.gilvum_PYR-GCK -----MTTTVLAYIPSPPQGVWYLGPFPLRAYALCIIVGIVAALVIGDRR : MSMEG_1517|M.smegmatis_MC2_155 GAPKVVRGG------------------ARFRMPGIERV-DIMSLEPFNVS Mvan_1428|M.vanbaalenii_PYR-1 GQPKVVRGG------------------ARFRVPGIERV-DIMSLEPFNVS MAB_3777|M.abscessus_ATCC_1997 GQPKVVRGG------------------ARFKMPGIERV-DIMSLEPFNVN MAV_3777|M.avium_104 QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVTIDNSD-NALPIEYSEVS MUL_2033|M.ulcerans_Agy99 QGAKTLRGGKMEDVIFAGTSLRAPLGRAEVTVTIDNSD-NALPIEYTEVS Mb1524|M.bovis_AF2122/97 GRYSRTVSG-----------------QLTLLVPFIDRVRARVDLRERVVS Rv1488|M.tuberculosis_H37Rv GRYSRTVSG-----------------QLTLLVPFIDRVRARVDLRERVVS MLBr_01802|M.leprae_Br4923 GRYGRTVSG-----------------QLTLLVLFIDRVRARVDLRERVVS TH_1418|M.thermoresistible__bu GRYSRTVSG-----------------QLTLLVPFIDRIRARVDLRERVVS MMAR_5349|M.marinum_M G---------------------------SFVVPFFRKV-RFLTLAMCEAE Mflv_3597|M.gilvum_PYR-GCK WVARGGEPG------------------VIYDIALWAVPFGLIGGRLYHVI : : . MSMEG_1517|M.smegmatis_MC2_155 IN----------------------LQNALSNNGVP--------------- Mvan_1428|M.vanbaalenii_PYR-1 IN----------------------LQNALSNNGVP--------------- MAB_3777|M.abscessus_ATCC_1997 IN----------------------LQNALYNNGVP--------------- MAV_3777|M.avium_104 ITRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEI MUL_2033|M.ulcerans_Agy99 ITRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEI Mb1524|M.bovis_AF2122/97 FP----------------------PQPVITEDNLT--------------- Rv1488|M.tuberculosis_H37Rv FP----------------------PQPVITEDNLT--------------- MLBr_01802|M.leprae_Br4923 FP----------------------PQPVITEDNLT--------------- TH_1418|M.thermoresistible__bu FP----------------------PRAVITQDNLT--------------- MMAR_5349|M.marinum_M VA-----------------------EKCVTQQGIT--------------- Mflv_3597|M.gilvum_PYR-GCK TDWPTYFGDGGAG---------PAAALRIWDGGLG--------------- : : .: MSMEG_1517|M.smegmatis_MC2_155 ----------VNVEAVGLVRIGSADE------AVQTAVQRFLTSDLNELQ Mvan_1428|M.vanbaalenii_PYR-1 ----------VNVEAVGLVRIGSADE------AVQTAVQRFLTSDLNELQ MAB_3777|M.abscessus_ATCC_1997 ----------VNVEAVGLVRIGSNDE------AVQTAVQRFLTSDLSELQ MAV_3777|M.avium_104 LQSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELR MUL_2033|M.ulcerans_Agy99 LQSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELR Mb1524|M.bovis_AF2122/97 ----------LNIDTVVYFQVT-----------VPQAAVYEISNYIVGVE Rv1488|M.tuberculosis_H37Rv ----------LNIDTVVYFQVT-----------VPQAAVYEISNYIVGVE MLBr_01802|M.leprae_Br4923 ----------LNIDTVVYFQVT-----------VPQAAVYEISNYIVGVE TH_1418|M.thermoresistible__bu ----------VSIDTVVYFRVN-----------NPHDAVYQISNYIAAVE MMAR_5349|M.marinum_M ----------LNVRAVIAFKVGNDTES-------IIAAAQRFLSEQDQMS Mflv_3597|M.gilvum_PYR-GCK ------IWGAVALGAVGAWIACRRRGIPLPAFGDAIAPGIVLAQAIGRLG . :. : . : MSMEG_1517|M.smegmatis_MC2_155 RQIN-------------------EILAGSLRGITATMTVEDLNSNR---- Mvan_1428|M.vanbaalenii_PYR-1 RQIN-------------------EILAGSLRGITATMTVEDLNSNR---- MAB_3777|M.abscessus_ATCC_1997 RQIN-------------------EILAGSLRGITATMTVEDLNSNR---- MAV_3777|M.avium_104 RQLKPLGRQAEVARRA-------QTIQADLRDARLRLAADDLVNRRGERE MUL_2033|M.ulcerans_Agy99 RQLKPLGRQAEVARRA-------QTIQADLRDARLRLAADDVVSRRAERE Mb1524|M.bovis_AF2122/97 QLTT-----------------------TTLRNVVGGMTLEQTLTSRDQ-- Rv1488|M.tuberculosis_H37Rv QLTT-----------------------TTLRNVVGGMTLEQTLTSRDQ-- MLBr_01802|M.leprae_Br4923 QLTT-----------------------TTLRNVVGGMTLEQTLTSRDQ-- TH_1418|M.thermoresistible__bu ELTT-----------------------TTLRNVVGGMTLEEALTSRDR-- MMAR_5349|M.marinum_M VLTG-------------------RIFAGHLRSIIGSMTVEEIIRER---- Mflv_3597|M.gilvum_PYR-GCK NYFNQELYGRETTVPWGLEIYERRNSAGVLDSLNGISTGELIGVVHPTFL * . : : : MSMEG_1517|M.smegmatis_MC2_155 -----DTLARSVVEEAGADLARIGMEVDVLK------------------- Mvan_1428|M.vanbaalenii_PYR-1 -----DTLARSVVDEAGGDLARIGMEVDVLK------------------- MAB_3777|M.abscessus_ATCC_1997 -----DSLARSVVEEAGGDLARIGMEVDVLK------------------- MAV_3777|M.avium_104 AIFEAEAAMRREHDEASARLAVASEELAAHEKALGELSGRAESVQQTWFA MUL_2033|M.ulcerans_Agy99 AIFEAEATMRREHDEAAARLTVAAEELAAHEATLAELTSRAESVQHTWFG Mb1524|M.bovis_AF2122/97 ----INAQLRGVLDEATGRWGLRVARVELRS------------------- Rv1488|M.tuberculosis_H37Rv ----INAQLRGVLDEATGRWGLRVARVELRS------------------- MLBr_01802|M.leprae_Br4923 ----INAQLRGVLDEATGRWGLRVARVELRS------------------- TH_1418|M.thermoresistible__bu ----INEQLRAVLDGATDRWGLRVQRVELKA------------------- MMAR_5349|M.marinum_M -----QKLATEVLDGSKEEMARIGLNVDALQ------------------- Mflv_3597|M.gilvum_PYR-GCK YELLWNLLVFAVLILVDRRFKIGHGRLFALY------------------- : .: MSMEG_1517|M.smegmatis_MC2_155 IAGISDRNGYLESLGQRRIAEVKRDATVG--------------TAEAERD Mvan_1428|M.vanbaalenii_PYR-1 IAGISDRNGYLESLGQRRIAEVKRDAAVG--------------TAEAERD MAB_3777|M.abscessus_ATCC_1997 IAGISDRNGYLESLGQRRIAEVRRDATVG--------------TAEAERD MAV_3777|M.avium_104 LSALAERVAATVRIASERAQHLDLGPVTAGDTDPDALDAEAERVAAAEQQ MUL_2033|M.ulcerans_Agy99 LSALAERVGTTVRIANERAQHLDVEPVTNSDTDPDALDAEAEQVAIAEQQ Mb1524|M.bovis_AF2122/97 -------------IDPPPSIQASMEKQMK---------------ADREKR Rv1488|M.tuberculosis_H37Rv -------------IDPPPSIQASMEKQMK---------------ADREKR MLBr_01802|M.leprae_Br4923 -------------IDPPPSIQTSMEKQMK---------------ADREKR TH_1418|M.thermoresistible__bu -------------IDPPPTIQDAMEKQMR---------------ADREKR MMAR_5349|M.marinum_M ----------IQSIDDDGLGYIDAMSAPHN--------------AAIQQQ Mflv_3597|M.gilvum_PYR-GCK VAGYCAGRFWIELMRSDTATLLAGIRVNTFTATFVFVAAVVYVIVAPKGR : . : MSMEG_1517|M.smegmatis_MC2_155 AQIQSAKARQEGSIAQAEADTAIASANQKRDVELARLRAQTEAENAQADQ Mvan_1428|M.vanbaalenii_PYR-1 AQIQSAKARQAGAVAQAEADTAIATANQKRDVELARLRAQTEAENAQADQ MAB_3777|M.abscessus_ATCC_1997 AQIQSAQARQAGAIAQAEADTAIATATQKRDVELARLRAQTEAENAQADQ MAV_3777|M.avium_104 LLAELAAARSRLETARAELAEREREAAEADRAHMAAVRAEADRREGLARL MUL_2033|M.ulcerans_Agy99 LLVELAEARDRLDAARAELADREHRAAEADRAHLAAVRAEADRREGLARL Mb1524|M.bovis_AF2122/97 AMILTAEGTREAAIKQAEGQKQAQILAAEGAKQAAILAAEADRQSRMLRA Rv1488|M.tuberculosis_H37Rv AMILTAEGTREAAIKQAEGQKQAQILAAEGAKQAAILAAEADRQSRMLRA MLBr_01802|M.leprae_Br4923 AMILTAEGTREAAIKQAEGNKQAQILAAEGAKQAVILAAEADRQSRMLRA TH_1418|M.thermoresistible__bu AMILTAEGQRESAIKEAEGQKQAQILAAEGAKQAAILTAEAERQSRILRA MMAR_5349|M.marinum_M AQIAQAQANQLSAEAEQESQRKQAEFARETAIVKAQYKAEVDKAQAQAAQ Mflv_3597|M.gilvum_PYR-GCK EAPESLRGNQDAESDVEDLAKDVALASAVGVVAAATVAGEDEKRDGGGSP . : . .: : . MSMEG_1517|M.smegmatis_MC2_155 AGPLANARAQKD--------VGIAIEQAEAARVQARIEVE---------- Mvan_1428|M.vanbaalenii_PYR-1 AGPLANARAQKD--------VGIAIEQAEAARVQARIEVE---------- MAB_3777|M.abscessus_ATCC_1997 AGPLAQARAEKD--------VGIAREQAEAARVQARTEVE---------- MAV_3777|M.avium_104 AGQVETMRARVESIDDSVARLSERIEAAAARAQQAKAEFETVQGRVGELD MUL_2033|M.ulcerans_Agy99 AGQVETMRARVESIDDSVARLSERIEHAAARAQQTRAEFETVQARVGELD Mb1524|M.bovis_AF2122/97 QGERAAAYLQAQG-------QAKAIEKTFAAIKAG--------------- Rv1488|M.tuberculosis_H37Rv QGERAAAYLQAQG-------QAKAIEKTFAAIKAG--------------- MLBr_01802|M.leprae_Br4923 QGKRAAAYLQAQG-------QAKAIEKTFAAIKAG--------------- TH_1418|M.thermoresistible__bu QGERAAQYLQAQG-------QAKAIEKTFAAIKAG--------------- MMAR_5349|M.marinum_M AGPLAEAQSQRE-----------VLEMRTELAERA--------------- Mflv_3597|M.gilvum_PYR-GCK PGGLGSVEGDEALEAAG--GASAANESAVEGAADAADLVALLEAS----- * * MSMEG_1517|M.smegmatis_MC2_155 ------------------------------QRRSEQAQAALQADVIAPAE Mvan_1428|M.vanbaalenii_PYR-1 ------------------------------QRRAEQSQAALQADVIAPAE MAB_3777|M.abscessus_ATCC_1997 ------------------------------QRRTEQAQAALQADVIAPAE MAV_3777|M.avium_104 QGEVGLDEHHERTVAALRLADERVAELQAAERDAERKVASLRARIDALAV MUL_2033|M.ulcerans_Agy99 QGEVGLDEQHERTVAALRLAEQRLAELQVAERDAERQVASLRARIGALSV Mb1524|M.bovis_AF2122/97 -------------------------------RPTPEMLAYQYLQTLP--- Rv1488|M.tuberculosis_H37Rv -------------------------------RPTPEMLAYQYLQTLP--- MLBr_01802|M.leprae_Br4923 -------------------------------RPTPEMLAYQYLQILP--- TH_1418|M.thermoresistible__bu -------------------------------RPTPELLAYQYLQTLP--- MMAR_5349|M.marinum_M ---------------------------------AELRQQELVAEVVKP-- Mflv_3597|M.gilvum_PYR-GCK -------------------------------EDVEVADGAVEPQEVDAPP MSMEG_1517|M.smegmatis_MC2_155 AQRQAD-------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 AQRAAD-------------------------------------------- MAB_3777|M.abscessus_ATCC_1997 ARRQAD-------------------------------------------- MAV_3777|M.avium_104 GLERKDGTAWLTENHSGAGILGPMAKLVKVRSGYEAAVAAVLGSAADALA MUL_2033|M.ulcerans_Agy99 GLDRKDGAAWLARNHSDAGLFGSVAQLVKVRSGYEAAVAAVLGSAAEALA Mb1524|M.bovis_AF2122/97 -------------------------------------------------- Rv1488|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01802|M.leprae_Br4923 -------------------------------------------------- TH_1418|M.thermoresistible__bu -------------------------------------------------- MMAR_5349|M.marinum_M -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK VPDEAG-------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------VARAEGQRQAAILAAEA-------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------IARAEGQRQATILA----------------------- MAB_3777|M.abscessus_ATCC_1997 -------------IAIAEGARQAAILKAQS-------------------- MAV_3777|M.avium_104 ADGLGAARSALGALKQADGGRAALVLGDWP--ADPPAPQPAPAGALWALD MUL_2033|M.ulcerans_Agy99 ADSFGAARSAVTALKQADGGRAALVLGDWPDAHDHRAAGGLPSGTLWALD Mb1524|M.bovis_AF2122/97 ------------EMARGDANKVWVVPSDFN-------------------- Rv1488|M.tuberculosis_H37Rv ------------EMARGDANKVWVVPSDFN-------------------- MLBr_01802|M.leprae_Br4923 ------------QMARGDANKVWVVPSDFS-------------------- TH_1418|M.thermoresistible__bu ------------KIAEGEASKVWIVPNDFG-------------------- MMAR_5349|M.marinum_M ------------AEAEAERVRILAVADAEK-------------------- Mflv_3597|M.gilvum_PYR-GCK ------------GLGAVEGEEAAEAAAGAG-------------------- : . MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3777|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_3777|M.avium_104 LIDAPERLRGAITAMLSGVAVVDDLDRALALVAEHPRLRAVTLDGDLVGA MUL_2033|M.ulcerans_Agy99 LIEVPSRLRPAMTAMLSGVVVVNDLSEALDLVQAQPQLRAVTLDGDLVGA Mb1524|M.bovis_AF2122/97 -------------------------------------------------- Rv1488|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01802|M.leprae_Br4923 -------------------------------------------------- TH_1418|M.thermoresistible__bu -------------------------------------------------- MMAR_5349|M.marinum_M -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3777|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_3777|M.avium_104 GWVSGGSDRKLSTLEVTSEIDKASAELAAAEAQVAQLSAALSGALAEQAA MUL_2033|M.ulcerans_Agy99 GWVSGGSDRKPSTLEITSEIDKARRELAAAEVRVAELGAALSGALTDQTA Mb1524|M.bovis_AF2122/97 -------------------------------------------------- Rv1488|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01802|M.leprae_Br4923 -------------------------------------------------- TH_1418|M.thermoresistible__bu -------------------------------------------------- MMAR_5349|M.marinum_M -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3777|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_3777|M.avium_104 RQDSAEQALAALNESDSAISGMYEQLGRLGQEARTSEDEWSRLLRQREEL MUL_2033|M.ulcerans_Agy99 RQDAAEQALAALNESDTAISAMYEQLGRIGQDARGAEEEWTRLLRQREEL Mb1524|M.bovis_AF2122/97 -------------------------------------------------- Rv1488|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01802|M.leprae_Br4923 -------------------------------------------------- TH_1418|M.thermoresistible__bu -------------------------------------------------- MMAR_5349|M.marinum_M -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3777|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_3777|M.avium_104 EAGRTQTVAEVTELENRLRNAQETPQEPAAEPVNRQQIAAATDAARSAEV MUL_2033|M.ulcerans_Agy99 EVGRTQTLEEVLELESRLRNAQESQHVQAAEPVDRQEIAAAAESARAIEV Mb1524|M.bovis_AF2122/97 -------------------------------------------------- Rv1488|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01802|M.leprae_Br4923 -------------------------------------------------- TH_1418|M.thermoresistible__bu -------------------------------------------------- MMAR_5349|M.marinum_M -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK --------------------------------------AARASVSDDAEA MSMEG_1517|M.smegmatis_MC2_155 AAEAKRRAGQAEADARKAAADALRVERQAEADS------------LQANL Mvan_1428|M.vanbaalenii_PYR-1 --------GQAEADARKAAADALRVERQAEAD------------------ MAB_3777|M.abscessus_ATCC_1997 DAEAERQKGAAEADARKAAADAFRVEQQAAADG------------AKAKL MAV_3777|M.avium_104 EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQQAREARLRAAAV MUL_2033|M.ulcerans_Agy99 EARLTVRTAEERANALRGRADSLRRVAAAEREARVRAELARAVRLRSAAV Mb1524|M.bovis_AF2122/97 ----AALQGFTRLLGKPGEDGVFRFEPSPVEDQP---------------- Rv1488|M.tuberculosis_H37Rv ----AALQGFTRLLGKPGEDGVFRFEPSPVEDQP---------------- MLBr_01802|M.leprae_Br4923 ----TALQGFTKLLGAPGEDGVFRFQPSPVDSSDQV-------------- TH_1418|M.thermoresistible__bu ----AALQGFTKLLGAPGEDGVFRFEPSPVEEDLP--------------- MMAR_5349|M.marinum_M ----MKIQAEAAASHNRVALDRMLIDQLPDIVEKAALG------------ Mflv_3597|M.gilvum_PYR-GCK SNDADAETEAAGLGSVDGDEVAAAVEDAPEVHEAAVEG------------ . MSMEG_1517|M.smegmatis_MC2_155 VAEAAGKKELADALRVEQQAEAAGIEARLLAEANGK-KEIAAALNSYTAE Mvan_1428|M.vanbaalenii_PYR-1 -----------------------GIKARLVAEAAGK-KEIAAALNTYSPE MAB_3777|M.abscessus_ATCC_1997 IAEADG-------TKAKLLADAEGIKAKLLAEADGK-KEVAAALNAYTPE MAV_3777|M.avium_104 AAAVADSGRLLATRLNAVVAAASRIRDALAAERQQRATAMTAVRDEVNAL MUL_2033|M.ulcerans_Agy99 AAAVAESGRLLAWRLNRVVDAASQLRDELAAERQQRSAAMSAVREETSSL Mb1524|M.bovis_AF2122/97 ---------------------------KHAADGDDAEVAGWFSTDTDPSI Rv1488|M.tuberculosis_H37Rv ---------------------------KHAADGDDAEVAGWFSTDTDPSI MLBr_01802|M.leprae_Br4923 --------------------------VKHAADEDDAEVADWFSVETDPAI TH_1418|M.thermoresistible__bu -----------------------------RPEDDSEEVADWFTTQTDPAI MMAR_5349|M.marinum_M ----------------------------LSGANLTVLNGADGLSQVAAGL Mflv_3597|M.gilvum_PYR-GCK ---------EAEAEELAAEAEVEAVAAEVAEVDADALTGADDDVDAETEA : MSMEG_1517|M.smegmatis_MC2_155 AARMLMLPDVLNSVVKATEAAASPLGEIERLSIIGG-------------- Mvan_1428|M.vanbaalenii_PYR-1 AARLQTLPDVLQSVVKATEAAAMPLSEIERLSIIGG-------------- MAB_3777|M.abscessus_ATCC_1997 AARLLTLPDILNSVVQATEAASKPIGEIENLSIIGG-------------- MAV_3777|M.avium_104 SARVAALTDSLHRDEVANAQAALRIEQLEQMVLEQFGMAPADLIAEYGPH MUL_2033|M.ulcerans_Agy99 SARVATLTDSLHRDEVANAQAALRIEQVEQMVLEQFGMAPSDLVAEYGPD Mb1524|M.bovis_AF2122/97 ARAVATAEAIARKPVEGSLGTPPRLTQ----------------------- Rv1488|M.tuberculosis_H37Rv ARAVATAEAIARKPVEGSLGTPPRLTQ----------------------- MLBr_01802|M.leprae_Br4923 AQAVAKAEAMVYQPVDE--------------------------------- TH_1418|M.thermoresistible__bu AQAVAKAEAEARTPVDTGLTTPPLTERSRQQELP---------------- MMAR_5349|M.marinum_M VSQGVAIFDAMRGSVADDNDGENAVAPWNAGTTDNV-------------- Mflv_3597|M.gilvum_PYR-GCK AVEGEAEAEELAAEADAEAQVAAEVAEVDADALTGADDDVDAETEAEVEG MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3777|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_3777|M.avium_104 IALPPSELEMAEYEQAKERGEQVFAPAPIPFDRPTQERRAKRAERELAEL MUL_2033|M.ulcerans_Agy99 VALPPTELEMAEFEQARERGEQVVAPAPMPFDRATQQRRAKRAERELTEL Mb1524|M.bovis_AF2122/97 -------------------------------------------------- Rv1488|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01802|M.leprae_Br4923 -------------------------------------------------- TH_1418|M.thermoresistible__bu -------------------------------------------------- MMAR_5349|M.marinum_M -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK EAEAEELAAEADAEAQVAAEVAEVDAETLTGADKDVDAEALTDADAETEA MSMEG_1517|M.smegmatis_MC2_155 ------------------------AGDAQDAVGGLLGISPLAVAKIIESL Mvan_1428|M.vanbaalenii_PYR-1 ------------------------ASDAQDAVGGLLGVSPLAVAKIVETL MAB_3777|M.abscessus_ATCC_1997 ------------------------AGDAQDALGTLFGVSPQAVAKVIESL MAV_3777|M.avium_104 GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLGVVDEVDARILQVF MUL_2033|M.ulcerans_Agy99 GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVVADVDARILQVF Mb1524|M.bovis_AF2122/97 -------------------------------------------------- Rv1488|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01802|M.leprae_Br4923 -------------------------------------------------- TH_1418|M.thermoresistible__bu -------------------------------------------------- MMAR_5349|M.marinum_M -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK AGLGSVDGDEVAAAVEDAPEVHEAAVEGESEAEELAAEADAEALAEVAEI MSMEG_1517|M.smegmatis_MC2_155 KSSGVDVAALLGGSGASTGPNGSN------VSTPPATNGDIAATAPAE-- Mvan_1428|M.vanbaalenii_PYR-1 KSSGIDVAAMLN-------PSPEP------PIAPAEANGEGAAQPL---- MAB_3777|M.abscessus_ATCC_1997 RVSGIDVPDLLKR--TQQADAPAS------PAPAPAVHPEGWVQE----- MAV_3777|M.avium_104 SEAYTDVEREFSDVFGVLFPGGEGRLRLTDPSNMLTTGIEVEARPPGKKI MUL_2033|M.ulcerans_Agy99 SDAFVDVEREFQIVFSSLFPGGEGRLRLTAPEDMLTTGIEVEARPPGKKV Mb1524|M.bovis_AF2122/97 -------------------------------------------------- Rv1488|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01802|M.leprae_Br4923 -------------------------------------------------- TH_1418|M.thermoresistible__bu -------------------------------------------------- MMAR_5349|M.marinum_M -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK DAEAVNDADEDVDAEAEAEAAGLGSVDGDEVAAAVEDAPEVREAVEGVAE MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3777|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_3777|M.avium_104 TRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDTNLRRLIS MUL_2033|M.ulcerans_Agy99 SRLSLLSGGEKALTAVAILVAIFRARPSPFYIMDEVEAALDDTNLRRLIG Mb1524|M.bovis_AF2122/97 -------------------------------------------------- Rv1488|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01802|M.leprae_Br4923 -------------------------------------------------- TH_1418|M.thermoresistible__bu -------------------------------------------------- MMAR_5349|M.marinum_M -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK VDAEALTDAEPEESDAEGEPEGPALPTSEHSPYTVVTESSSEPAQSGPAG MSMEG_1517|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1428|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3777|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_3777|M.avium_104 LFELLRARSQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRMRGQQV MUL_2033|M.ulcerans_Agy99 LFEMLRDRSQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRIRGQQV Mb1524|M.bovis_AF2122/97 -------------------------------------------------- Rv1488|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01802|M.leprae_Br4923 -------------------------------------------------- TH_1418|M.thermoresistible__bu -------------------------------------------------- MMAR_5349|M.marinum_M -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK LVRQWIRRRRNR-------------------------------------- MSMEG_1517|M.smegmatis_MC2_155 -------- Mvan_1428|M.vanbaalenii_PYR-1 -------- MAB_3777|M.abscessus_ATCC_1997 -------- MAV_3777|M.avium_104 DQLVTT-- MUL_2033|M.ulcerans_Agy99 DRLVANSS Mb1524|M.bovis_AF2122/97 -------- Rv1488|M.tuberculosis_H37Rv -------- MLBr_01802|M.leprae_Br4923 -------- TH_1418|M.thermoresistible__bu -------- MMAR_5349|M.marinum_M -------- Mflv_3597|M.gilvum_PYR-GCK --------