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SFVVANTEFVSGAAGNLARLGSMISAANSAAAAQTTAVAAAGADEVSAAVAALFGAHGQTYQVLSAQAAA FHSQFVQALSGGAQAYAAAEATNFGPLQPLFDVINAPTLALLNRPLIGNGADGTAANPNGQAGGLLIGNG GNGFSPAAGPGGNGGAAGLLGHGGNGGVGALGANGGAGGTGGWLFGNGGAGGNSGGGGGAGGIGGSAVLF GAGGAGGISPNGMGAGGSGGNGGLFFGNGGAGASSFLGGGGAGGRAFLFGDGGAGGAALSAGSAGRGGDA GFFYGNGGAGGSGAGGASSAHGGAGGQAGLFGNGGEGGDGGALGGNGGNGGNAQLIGNGGDGGDGGGAGA PGLGGRGGLLLGLPGANGT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1468c | PE_PGRS29 | - | 100% (370) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv1396c | PE_PGRS25 | e-107 | 55.89% (399) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv1067c | PE_PGRS19 | e-106 | 51.38% (436) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1503c | PE_PGRS29 | 0.0 | 100.00% (370) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 3e-54 | 48.26% (259) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01183 | - | 3e-12 | 36.46% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-26 | 35.69% (283) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_2274 | - | 1e-139 | 68.46% (371) | PE-PGRS family protein |
| M. avium 104 | MAV_1346 | - | 1e-19 | 32.95% (264) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-54 | 43.14% (299) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 7e-34 | 38.98% (254) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1145 | - | 1e-113 | 59.14% (394) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_0928 | - | 1e-53 | 46.59% (279) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKF
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 MSGTQSAESDDDADDSEGDASADDAEDAEEFVGDSGNGGSDDDAADDSEK
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------MSIIDFILNLFRDPVEAASYVADPEA
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PAALAPESPLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATS
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 DVDSSTDDGVGDFEGVVLDDAESEADSQLSVPQPASTESTEQSADVANDA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNL
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------------------------------------------------MV
MSMEG_0868|M.smegmatis_MC2_155 TNTTDQPTSDSLGAQPTAQVARQVQAPAT--DPAPAAPSLRPISGLLSVV
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 DGNADPIADAGPEAVTAPVALSGASAPAIPDGPAPVEPMGPLINSLWWAV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 QNYYAAQPDG--PSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMS
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK TFGGGATPTP----------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 TLGTTLIPNAPTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPV
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 PKSGGRSTNDAS--------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 PSGNVDSFNR----------------------------------------
Rv1468c|M.tuberculosis_H37Rv ----------------------------------------------MSFV
Mb1503c|M.bovis_AF2122/97 ----------------------------------------------MSFV
MMAR_2274|M.marinum_M ----------------------------------------------MSFV
MUL_1145|M.ulcerans_Agy99 ----------------------------------------------MSYV
Mflv_5091|M.gilvum_PYR-GCK TSLGAAAVDLS------------------------GTSCG----------
MSMEG_0868|M.smegmatis_MC2_155 PTVASAVLDPTQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQY
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 LTLAGTGIYPSVTS-----------------LFAFGGRCG----------
MLBr_01183|M.leprae_Br4923 ---------------------------------------------MPLFL
MAV_1346|M.avium_104 ---------------------------------------------MS-FV
MAB_4284c|M.abscessus_ATCC_199 -------------------------------GPLLDLSFGDLQFGNRDTT
Rv1468c|M.tuberculosis_H37Rv VANTEFVSGAAGNLARLGSMISAANSAAAAQTTAVAAAGADEVSAAVAAL
Mb1503c|M.bovis_AF2122/97 VANTEFVSGAAGNLARLGSMISAANSAAAAQTTAVAAAGADEVSAAVAAL
MMAR_2274|M.marinum_M IADTQWVSEAAGNLARIGSLIETANSAAATQTTAVTAAAADEVSAAVASL
MUL_1145|M.ulcerans_Agy99 VASPEYVAAAASDLAGIGSALSTANAAAAAPTIEVLAAGADEVSAAIAAF
Mflv_5091|M.gilvum_PYR-GCK LICNGQDGTGQN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGN
MSMEG_0868|M.smegmatis_MC2_155 LIGNGINGTADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-N
TH_3810|M.thermoresistible__bu ---------------------------------VDGDGGSGGRTGLFS--
Mvan_0928|M.vanbaalenii_PYR-1 LICDGADGTEQNPNGVGGGWLFGDGGDGWSSTLAGIAGGKGGAAGLLWGS
MLBr_01183|M.leprae_Br4923 NAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHF
MAV_1346|M.avium_104 TTRPEALLAVASMLEGLGSSMDAQNAAAAAPTTSIAPAAADEVSALQAAQ
MAB_4284c|M.abscessus_ATCC_199 AIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQ
.
Rv1468c|M.tuberculosis_H37Rv FGAHGQTYQVLSAQAAAFHSQFVQALSGGAQAYAAAEATNFGPLQPLFDV
Mb1503c|M.bovis_AF2122/97 FGAHGQTYQVLSAQAAAFHSQFVQALSGGAQAYAAAEATNFGPLQPLFDV
MMAR_2274|M.marinum_M FGSHGQSFQAVSLQAAAFHERFVQTLFGGAAAYTAAEAASVNPLQPLLDV
MUL_1145|M.ulcerans_Agy99 FGAHAQAYQALSEQASAFHLQFVQAMTAGAGAYAGAEAVNASPLQAALDV
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--AP
MSMEG_0868|M.smegmatis_MC2_155 GGNGGVGWAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTG
TH_3810|M.thermoresistible__bu -----------------------KLSRGGDGGDGGLG-------------
Mvan_0928|M.vanbaalenii_PYR-1 GGDGGAGGAGAAGGTGGNAG--LLWGNGGHGGAGGAGVNG--------AV
MLBr_01183|M.leprae_Br4923 FSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETAN----------
MAV_1346|M.avium_104 FSAYGTWYQQVSAQAKAIHQTLVQNLDTNADSYGATEAANRVNTSAAALQ
MAB_4284c|M.abscessus_ATCC_199 TRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGS
.
Rv1468c|M.tuberculosis_H37Rv INAPTLALLNRPLIGNG--------------ADGTAANPNGQAGG-----
Mb1503c|M.bovis_AF2122/97 INAPTLALLNRPLIGNG--------------ADGTAANPNGQAGG-----
MMAR_2274|M.marinum_M INAPTQLLLNRPLIGNG--------------TDGTAANPNGGAGG-----
MUL_1145|M.ulcerans_Agy99 LNAPAQALFGRPLIGDG--------------AGG-APGQSGGDGG-----
Mflv_5091|M.gilvum_PYR-GCK GVAGATGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-----
MSMEG_0868|M.smegmatis_MC2_155 GTGGTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFG
TH_3810|M.thermoresistible__bu GNGGHGGGTGIIS--------------------LLSLAGNGGNGG-----
Mvan_0928|M.vanbaalenii_PYR-1 GTSGVNNGRGGDG----------------------TAGGSGGAGG-----
MLBr_01183|M.leprae_Br4923 ------------------------------------HDSL----------
MAV_1346|M.avium_104 GLAPNVIPNAAPAADPP----------------PAGTTSLGTSIG-----
MAB_4284c|M.abscessus_ATCC_199 GNTTNTEIGSHNQANIG---------------TSTSAGGSAAVGG-----
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------AVG--SAGAAGEAGETGTWGNAGLPGKAGDAGGAG----AV
MSMEG_0868|M.smegmatis_MC2_155 YVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILI
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv1468c|M.tuberculosis_H37Rv -------LLIGNGGNGFSPAAG-------PGGNGGAAG------------
Mb1503c|M.bovis_AF2122/97 -------LLIGNGGNGFSPAAG-------PGGNGGAAG------------
MMAR_2274|M.marinum_M -------LLIGDGGKGFSSATAG-----VAGGSGGSAG------------
MUL_1145|M.ulcerans_Agy99 -------LLYGNGGNGGNGGVG------QAGGAGGAAG------------
Mflv_5091|M.gilvum_PYR-GCK GAAG---AAGTVGTAGATGGTG----TGANGGAGGVG-----GVGGTGAA
MSMEG_0868|M.smegmatis_MC2_155 GANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEG
TH_3810|M.thermoresistible__bu --NG----YRTTDNNALDGGHG------GNGGN-----------------
Mvan_0928|M.vanbaalenii_PYR-1 -------NAGLLSGRGGDGGVG------GAGGKGGAG-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----WAQNVGAAASDFITLGEGQFAPVPGAAGIPN---------------
MAB_4284c|M.abscessus_ATCC_199 -------NAGLAGNAGLAGNAG------LAGNAGLAG-------------
Rv1468c|M.tuberculosis_H37Rv -------------------------------------LLGHGGNGGVGA-
Mb1503c|M.bovis_AF2122/97 -------------------------------------LLGHGGNGGVGA-
MMAR_2274|M.marinum_M -------------------------------------LFGSGGAGGTGG-
MUL_1145|M.ulcerans_Agy99 -------------------------------------LIGNGGSGGIGGP
Mflv_5091|M.gilvum_PYR-GCK GAAGGAG------GLGETGTTG--------------GAGGVGGQGTAGGT
MSMEG_0868|M.smegmatis_MC2_155 TATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGT
TH_3810|M.thermoresistible__bu ------------VGFFSLFNLG--------------GAGGWGGSGVDG--
Mvan_0928|M.vanbaalenii_PYR-1 -------------AHGSDAVAAE-------------EDGGPGGSGGAGGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------------------------------------FNPGLTAATTAGP-
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------NAGLAGNAGLAG-
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GTTGLAGGAGGSGGWLFGNGGTGGRGGIGTTGIGGIGGTGGDAVGLFGHG
Mflv_5091|M.gilvum_PYR-GCK GGVGGIG------------------------GAGSTGAVGG---------
MSMEG_0868|M.smegmatis_MC2_155 GGAGGMGEIYSGADGEATGISAGGDGG-SATGADSLGGRGGTSWVQAGYG
TH_3810|M.thermoresistible__bu -----------------------------------VDVVGG---------
Mvan_0928|M.vanbaalenii_PYR-1 AG---------------------------------AGGVGG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv1468c|M.tuberculosis_H37Rv --------------LGANGGAGGTGG------------------------
Mb1503c|M.bovis_AF2122/97 --------------LGANGGAGGTGG------------------------
MMAR_2274|M.marinum_M --------------GGALGGNGGTGG------------------------
MUL_1145|M.ulcerans_Agy99 GTGGTGGNGPDIFIAGGAGGSGGTGG------------------------
Mflv_5091|M.gilvum_PYR-GCK --VGGKGIQGGQGLQGGKGGDGGAGGKGGDADSMGS--------------
MSMEG_0868|M.smegmatis_MC2_155 PTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGG
TH_3810|M.thermoresistible__bu ------------------NPDGGTPG------------------------
Mvan_0928|M.vanbaalenii_PYR-1 ----------RGALLFGRGGDGGDGG------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ---------------PAPAAPAAAAG------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------NAGLAGNAGLAG------------------------
Rv1468c|M.tuberculosis_H37Rv ------WLFGNGGAGGNSGGGG----------------------------
Mb1503c|M.bovis_AF2122/97 ------WLFGNGGAGGNSGGGG----------------------------
MMAR_2274|M.marinum_M ------LLLGNGGAGG-MGGTG----------------------------
MUL_1145|M.ulcerans_Agy99 ------LLFGNGGAGGGAPWGG----------------------------
Mflv_5091|M.gilvum_PYR-GCK ----AGATGGKGGNGGNGGRGGLFG---------------KGGNAGNG--
MSMEG_0868|M.smegmatis_MC2_155 NGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGN
TH_3810|M.thermoresistible__bu ------AHGESHTPGVYTDRQ-----------------------------
Mvan_0928|M.vanbaalenii_PYR-1 -------SAGTGGAGGFGGTG-----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----APVLASMGRGPSIGGLSVP---------------------------
MAB_4284c|M.abscessus_ATCC_199 -------NAGLAGNAGLAGNAG----------------------------
Rv1468c|M.tuberculosis_H37Rv --------------------------GAGGIGGSAVLFGAGGAG------
Mb1503c|M.bovis_AF2122/97 --------------------------GAGGIGGSAVLFGAGGAG------
MMAR_2274|M.marinum_M --------------------------STAGAGGSALLIGMGGAG------
MUL_1145|M.ulcerans_Agy99 --------------------------ADGGAGGDARLIGNGGGGGYEGSL
Mflv_5091|M.gilvum_PYR-GCK --------------------ADGGTGGAGGAGGTGG-TGGAGGTGG----
MSMEG_0868|M.smegmatis_MC2_155 GWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASV
TH_3810|M.thermoresistible__bu --------------------------GEDGEDGTGTGIGGRGGNGG----
Mvan_0928|M.vanbaalenii_PYR-1 -----------------------GAIVVTLPGGKLSDSDGAGGAGG----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------PSWAPGGVAPAANATPAQLVG---
MAB_4284c|M.abscessus_ATCC_199 ------------------------LAGNAGLAGNAGLAGNAGLAGN----
Rv1468c|M.tuberculosis_H37Rv --------------------------------GISPNGMGAGGSGGNGGL
Mb1503c|M.bovis_AF2122/97 --------------------------------GISPNGMGAGGSGGNGGL
MMAR_2274|M.marinum_M --------------------------------GTS-GLAGIGGLGGNGGL
MUL_1145|M.ulcerans_Agy99 GVLSGGTAGPGGDGGNAVGLIGNGGAGGAGAAGLSGVTGGIGGNGGNGAQ
Mflv_5091|M.gilvum_PYR-GCK -------------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 WKANGQHST------GQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGV
TH_3810|M.thermoresistible__bu ------------------SSSGTHPMAEDG--------EHVKALDGRPGL
Mvan_0928|M.vanbaalenii_PYR-1 -------------------VGGAAGLGGDGGGGGLGGLLGQAGVNGDSGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----------------------------AGFTSAAPDTAPVTAVPGGVP
MAB_4284c|M.abscessus_ATCC_199 -----------------------AGLAGNAGLAGNAGLAGNAGLAGNAGL
Rv1468c|M.tuberculosis_H37Rv FFGNGGAGASS------FLGGGGAGGRAFLFGDGGAGGAA----------
Mb1503c|M.bovis_AF2122/97 FFGNGGAGASS------FLGGGGAGGRAFLFGDGGAGGAA----------
MMAR_2274|M.marinum_M LFGNAGDGGSG------VFGGG-NGGRAWLLGNGGAGGDS----------
MUL_1145|M.ulcerans_Agy99 LFGNGGAGGAGGQSQLASGGTGGSGGMAALFGNGGAGGAAGVSLSGAPGT
Mflv_5091|M.gilvum_PYR-GCK G-GTGGTGGTG--------GTGGKGGTGGTGGAGGTG----GDGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 SEGEGGTGGHG--------GDGGRGGDGALGGNGGTGGVGLGNGGKGGNG
TH_3810|M.thermoresistible__bu D---GGNGSHG--------GNGGHGGRGGFLGIGGSG-------GWGGHG
Mvan_0928|M.vanbaalenii_PYR-1 TAAAGNAGGVG--------GAGGLGGRLPIVDLNNASPAQATLAALIKKL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 SMATAGRGGYG-------LGAPRYGVKPTVMPKPAI--------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGGVLNTGVSGAIGG
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GGNGGSAQFMGDGDSGGLGDSGGSAGAAGAGGLIGNPLDVVNAPTEALLG
Mflv_5091|M.gilvum_PYR-GCK GTGGTG--------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGTYV----------------------------------------
TH_3810|M.thermoresistible__bu GNGGD---------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 GLPIQAATG-----------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SSHVGG--------------------------------------------
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 RPLIGDGADGAPGESGQDGGLLYGNGGNGGNGLSGQAGGAGGAAGLIGNG
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GNGGIGGPGTTGMSGGAGGAGGWLIGNGGHGGIGGLGIGIGDSGGAGGAG
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GAAIGLFGNGGTGGTGGYNQAFGAVSGVGGAGGAGGQWYGNGGDGGTSWG
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GAAAGAGGDAGLIDNGGDGDSAGVLRQNGIGGHGGAGGSLFGDGGDGGSA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GFQSTAGDGGNAGLVGNGGNGGWAIYNSFAGDDGSGGTAIGNGGDGGANI
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv1468c|M.tuberculosis_H37Rv ------LSAGSAGRGGDAG-----------FFYGNGGAGG----------
Mb1503c|M.bovis_AF2122/97 ------LSAGSAGRGGDAG-----------FFYGNGGAGG----------
MMAR_2274|M.marinum_M ------SSMGNSGNGGNAG-----------FFVGNGGIGG----------
MUL_1145|M.ulcerans_Agy99 VSSGFILGAGGGGNGGNAV-----------GLIGNGGAGG----------
Mflv_5091|M.gilvum_PYR-GCK ------GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQGG
MSMEG_0868|M.smegmatis_MC2_155 -DPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGG
TH_3810|M.thermoresistible__bu -------TDADGGNGGDG---------------GNGGSAG----------
Mvan_0928|M.vanbaalenii_PYR-1 ----IQLEDVDGRLVGPLNAYLYN-----TIIGKAIFDVGNTFSSASLSA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----AINESLGGSGSVGG----------STAVGGGAHTG----------
Rv1468c|M.tuberculosis_H37Rv ------------------------SGAGGASSAHGGAGGQAG--------
Mb1503c|M.bovis_AF2122/97 ------------------------SGAGGASSAHGGAGGQAG--------
MMAR_2274|M.marinum_M ------------------------TGG---SNANGGVGGQAG--------
MUL_1145|M.ulcerans_Agy99 ------------------------TGADGFSTALGSDGGNGGTGA-----
Mflv_5091|M.gilvum_PYR-GCK QGGQGG-----------------TGGTGGQGG-LGGGGGTG---------
MSMEG_0868|M.smegmatis_MC2_155 KGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYN
TH_3810|M.thermoresistible__bu -----------------------RGGTGGLRGVFGINGGNG---------
Mvan_0928|M.vanbaalenii_PYR-1 RVKEIVILS--------------VGGQWGSEYELYAHKLAAQLFG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------VGGGVSTGVGVGSHVGGGISES-----
Rv1468c|M.tuberculosis_H37Rv ---------------LFGNGGEGGDGGALG--------------------
Mb1503c|M.bovis_AF2122/97 ---------------LFGNGGEGGDGGALG--------------------
MMAR_2274|M.marinum_M ---------------LIGNGGAGGDGGGVS--------------------
MUL_1145|M.ulcerans_Agy99 --------------WLLGNGGAGGSGGSTAGVHPAGDGGNSGMSALIGNG
Mflv_5091|M.gilvum_PYR-GCK --------------GQGGTGGTGGQGGTGGTGGTGGTG------------
MSMEG_0868|M.smegmatis_MC2_155 VVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGI----
TH_3810|M.thermoresistible__bu ---------------RAGLGGRGXXXXGGGVG------------------
Mvan_0928|M.vanbaalenii_PYR-1 ----------IPADAIAALANGQAPVGLSGNELLAAQFVQELVSTR----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------LGGSGSVGGSTAVGGG-------------------
Rv1468c|M.tuberculosis_H37Rv ---------------GNGGNGGNAQLIGNGGDGGDGGGAGAPGLGGRGGL
Mb1503c|M.bovis_AF2122/97 ---------------GNGGNGGNAQLIGNGGDGGDGGGAGAPGLGGRGGL
MMAR_2274|M.marinum_M ---------------GNGGNGGNALLIGNGGDGGTGGGTGTDGLGGTRGL
MUL_1145|M.ulcerans_Agy99 GAGGSAGVSPTGVFPSNGGSGGNAQLIGDGGDGGRGDSGGTGGAGGTGGS
Mflv_5091|M.gilvum_PYR-GCK ---------------GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGS
MSMEG_0868|M.smegmatis_MC2_155 ---------------GAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSA
TH_3810|M.thermoresistible__bu ----------------AAVRSGNGVFSGGGGTPSAGFGVPTTIQFPAGSC
Mvan_0928|M.vanbaalenii_PYR-1 ---------------RVSDALFEAAEAAFGQTGVVDMVNLAGTYLGVSAT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------AHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGS
Rv1468c|M.tuberculosis_H37Rv LLGLPGANGT----------------------------------------
Mb1503c|M.bovis_AF2122/97 LLGLPGANGT----------------------------------------
MMAR_2274|M.marinum_M LFGQDGTNG-----------------------------------------
MUL_1145|M.ulcerans_Agy99 LAGHDGSDGD----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK TGGAGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQ
MSMEG_0868|M.smegmatis_MC2_155 TGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGE
TH_3810|M.thermoresistible__bu TSRAVSREG------------------------IMPSSRAASARAG----
Mvan_0928|M.vanbaalenii_PYR-1 LNAFKVRGP---------------ESFSAPVLPAAPSPVPASDEYGLGGR
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TAVGGGAHTG--------------------VGGGVNTGVGVGSHVGGGIS
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGAQGATG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG---
MSMEG_0868|M.smegmatis_MC2_155 ASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFS
TH_3810|M.thermoresistible__bu -----------------------AACASSTSRSRRSFCCSRA--------
Mvan_0928|M.vanbaalenii_PYR-1 LPLIDLDTATPAQLDLAAKIKALAVPTQQATGIELVSPDGRLIGPLNG--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ESLGGSGSVGGSTAVGGGAHTSAINDALGGSGSVGGSTAVGGG-------
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG-----
MSMEG_0868|M.smegmatis_MC2_155 NIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIAN
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 ---YLYNPVIGQALFEVGNAFASSSLSSRIKEIVILSVGGQWGSGYEVYA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------AHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAGTGFEA
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---AAGEDGDAGSGGSG-INGGAGGAGG-----------------AGGEG
MSMEG_0868|M.smegmatis_MC2_155 SSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 HEKVARLVGIPEEAIVSLASGHAPVGLS-------------GSELVAARF
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 QGHAQGHASETAHTTLPGAEHH----------------------------
Rv1468c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1503c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2274|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GEGGDGGKGGAG--AEGGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGS
MSMEG_0868|M.smegmatis_MC2_155 GNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 VQELVSTYEVSSELYHSAEAAFGQAGLVDLVNLASTYLGASALLNVFEVP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv1468c|M.tuberculosis_H37Rv ------------
Mb1503c|M.bovis_AF2122/97 ------------
MMAR_2274|M.marinum_M ------------
MUL_1145|M.ulcerans_Agy99 ------------
Mflv_5091|M.gilvum_PYR-GCK GGSGGAAGDSDD
MSMEG_0868|M.smegmatis_MC2_155 PGTAGTTGANNP
TH_3810|M.thermoresistible__bu ------------
Mvan_0928|M.vanbaalenii_PYR-1 VPTAALITTS--
MLBr_01183|M.leprae_Br4923 ------------
MAV_1346|M.avium_104 ------------
MAB_4284c|M.abscessus_ATCC_199 ------------