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M. leprae Br4923 MLBr_00589 (-)

annotation: hypothetical protein MLBr_00589
coordinates: 714243 - 715040
length: 265

TQNNTLRNSPLFPAGTFTPNPRPNAVTRMVAAQFMLELKLLLRNGEQLLLTMFIPITLLIGLTLLPLGSF
GHHRATTFVPVIMALAVVSSAFTGQAIAVAFDRRYGALKRFGATPLPVWGIIAGKSLAVVTVVFLQAIIL
GAIGVMLGWRPALICLALGAAIIALGTAGLAALGLLLGGTLRAEIVLAVANLMWFVFAGLGALTVKMNMI
SAVVKWAARLTPSGALTEALSQAMTLSVDWFGVIILTAWGTLAALAALHWFRFT*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00589--100% (265)hypothetical protein MLBr_00589
M. leprae Br4923MLBr_02350-4e-0526.81% (138) putative antibiotic resistance membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1492c-1e-12183.08% (260) unidentified antibiotic-transport integral membrane ABC
M. gilvum PYR-GCKMflv_3681-1e-10978.57% (252) multidrug ABC transporter inner membrane protein
M. tuberculosis H37RvRv1457c-1e-12183.08% (260) unidentified antibiotic-transport integral membrane ABC
M. abscessus ATCC 19977MAB_2753-3e-9870.00% (260) ABC transporter permease
M. marinum MMMAR_2262-1e-12183.40% (265) antibiotic ABC transporter transmembrane protein
M. avium 104MAV_3322-1e-11983.66% (257) ABC transporter efflux protein, DrrB family protein
M. smegmatis MC2 155MSMEG_3118-1e-10877.08% (253) ABC transporter efflux protein, DrrB family protein
M. thermoresistible (build 8)TH_0342-1e-10475.29% (255) PROBABLE UNIDENTIFIED ANTIBIOTIC-TRANSPORT INTEGRAL MEMBRANE
M. ulcerans Agy99MUL_1858-1e-12183.02% (265) antibiotic ABC transporter transmembrane protein
M. vanbaalenii PYR-1Mvan_2729-1e-10877.08% (253) multidrug ABC transporter inner membrane protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3681|M.gilvum_PYR-GCK          MS------VENRFAPGTFTPDPRPAKVPKMLAAQFALELRLLLRNGEQLL
Mvan_2729|M.vanbaalenii_PYR-1       MT------TENRFTPGTFTPDPRPAPVPRMLAAQFRLELRLLLRNGEQLL
MSMEG_3118|M.smegmatis_MC2_155      MTSP----AANRFAPGTFTPDPRPATVQKMLAAQFGLELRLLLRNGEQLL
TH_0342|M.thermoresistible__bu      --------VTNRFPAGTFTPDPRPAPVPRMLAAQYGLELKLLLRNGEQLL
Mb1492c|M.bovis_AF2122/97           MTQTN----RPAFPAGTFSPDPRPNAVPLMLAAQFSLELKLLLRNGEQLL
Rv1457c|M.tuberculosis_H37Rv        MTQTN----RPAFPAGTFSPDPRPNAVPLMLAAQFSLELKLLLRNGEQLL
MLBr_00589|M.leprae_Br4923          MTQNNTLRNSPLFPAGTFTPNPRPNAVTRMVAAQFMLELKLLLRNGEQLL
MMAR_2262|M.marinum_M               MTQTN---GEGTFPVGTFTPDPRPSAVPRMLAAQFGLELKLLLRNGEQLL
MUL_1858|M.ulcerans_Agy99           MTQTN---GEGTFPVGTFTPDPRPSAVPRMLAAQFGLELKLLLRNGEQLL
MAV_3322|M.avium_104                MTDS------GVFPVGTFTPNPRPSAVPKMLAAQYGLELKLLLRNGEQLL
MAB_2753|M.abscessus_ATCC_1997      MTDTT----TPRFDPGTFTPDPRPSAVHTMLFAQFWLELKLLLRNGEQLL
                                                *  ***:*:***  *  *: **: ***:**********

Mflv_3681|M.gilvum_PYR-GCK          LTMFIPITLLIGLILLPLGSFGPNRAATFVPAIMALAVISTAFTGQAIAV
Mvan_2729|M.vanbaalenii_PYR-1       LTMFIPITLLVGLTLLPLGSFGDNRAATFVPAIMALAVISTAFTGQAIAV
MSMEG_3118|M.smegmatis_MC2_155      LTMFIPITLLIGLTLLPLGSFGDDRAGAFTPAIMALAVISTAFTGQAIAV
TH_0342|M.thermoresistible__bu      LTLFIPITLLVGLILLPLGDFGDDRASRFVPAIMALAVISTAFTGQAIAV
Mb1492c|M.bovis_AF2122/97           LTMFIPITLLVGLTLLPMGSFGHNRAATFVPVIMALAVISTAFTGQAIAV
Rv1457c|M.tuberculosis_H37Rv        LTMFIPITLLVGLTLLPMGSFGHNRAATFVPVIMALAVISTAFTGQAIAV
MLBr_00589|M.leprae_Br4923          LTMFIPITLLIGLTLLPLGSFGHHRATTFVPVIMALAVVSSAFTGQAIAV
MMAR_2262|M.marinum_M               LTMFIPITLLIGLTLLPLGSFGQHRAATFVPVIMALAVISTAFTGQAIAV
MUL_1858|M.ulcerans_Agy99           LTMFIPITLLIGLTLLPLGSFGQHRAATFVPVIMALAVISTAFTGQAIAV
MAV_3322|M.avium_104                LTMFIPITLLVGLTLLPLGSFGQHRAATFTPVIMALAVISTAFTGQAIAV
MAB_2753|M.abscessus_ATCC_1997      LTMFIPITLLIGLTLLPLGQFPGSRTDIFVPAIMALAVISTAFTGQAIAV
                                    **:*******:** ***:*.*   *:  *.*.******:*:*********

Mflv_3681|M.gilvum_PYR-GCK          AFDRRYGALKRLGATALPVWGVIAGKSLAVVTVVSLQSVLFGAIGFALGW
Mvan_2729|M.vanbaalenii_PYR-1       AFDRRYGALKRLGATALPVWGIIAGKSLAVGAVVILQSILFGAIGFALGW
MSMEG_3118|M.smegmatis_MC2_155      AFDRRYGALKRLGATALPVWGIIAGKSLAVVAVVFLQAVLLGAIGVALGW
TH_0342|M.thermoresistible__bu      AFDRRYGALKRLGATALPVWGIIVGKSLAVVTVVFVQSVVLGAIGAALGW
Mb1492c|M.bovis_AF2122/97           AFDRRYGALKRLGATPLPVWGIIAGKSLAVVAVVFLQAIILGAIGFALGW
Rv1457c|M.tuberculosis_H37Rv        AFDRRYGALKRLGATPLPVWGIIAGKSLAVVAVVFLQAIILGAIGFALGW
MLBr_00589|M.leprae_Br4923          AFDRRYGALKRFGATPLPVWGIIAGKSLAVVTVVFLQAIILGAIGVMLGW
MMAR_2262|M.marinum_M               AFDRRYGALKRLGATPLPVWGIIAGKSLAVVAVVFLQAIVLGAIGFALGW
MUL_1858|M.ulcerans_Agy99           AFDRRYGALKRLGATPLPVWGIIAGKSLAVVAVVFLQAIVLGAIGFALGW
MAV_3322|M.avium_104                AFDRRYGALKRLGATPLPVWGIIAGKSLAVVTVVFLQAILLGAIGFALGW
MAB_2753|M.abscessus_ATCC_1997      GFDRRYGALKRLGATALPVWGIIAGKALAVVTVVVLQAAVIGAIGGALGW
                                    .**********:***.*****:*.**:*** :** :*: ::****  ***

Mflv_3681|M.gilvum_PYR-GCK          RPPLAGLALGALIIALGTAVFAALGLLLGGTLRAEIVLALANLLWFVFAG
Mvan_2729|M.vanbaalenii_PYR-1       RPPLAGLALGAVIIALGTAVFAALGLLLGGTLRAEIVLALANLLWFVFAG
MSMEG_3118|M.smegmatis_MC2_155      RPPLAGLALGAVIIALGTAGFAAMGLLLGGTLRSEIVLALANLLWFVFAG
TH_0342|M.thermoresistible__bu      RPQPAGLLLGAVIIALGTAVFAALGLLLGGTLRAEIVLAVANLLWFVFAA
Mb1492c|M.bovis_AF2122/97           RPALTALTLGAGIIALGTAGFAALGLLLGGTLRAEIVLAVANLMWFVFAG
Rv1457c|M.tuberculosis_H37Rv        RPALTALTLGAGIIALGTAGFAALGLLLGGTLRAEIVLAVANLMWFVFAG
MLBr_00589|M.leprae_Br4923          RPALICLALGAAIIALGTAGLAALGLLLGGTLRAEIVLAVANLMWFVFAG
MMAR_2262|M.marinum_M               RPALAALALGGAVIALGTAGFAALGLLLGGTLRAEIVLAVANLMWFVFAG
MUL_1858|M.ulcerans_Agy99           RPALAALALGGAVIALGTAGFAALGLLLGGTLRAEIVLAIANLMWFVFAG
MAV_3322|M.avium_104                RPALAALALGAAVIALGTAVFAALGLLLGGTLRAEIVLALANLMWFVFAG
MAB_2753|M.abscessus_ATCC_1997      RPHPVGLLVGAVVIAIGTAAFVAMGLLLGGTLRAEIVLALANLLWFIFAG
                                    **    * :*. :**:*** :.*:*********:*****:***:**:**.

Mflv_3681|M.gilvum_PYR-GCK          LGALVLERG----MVPAAVQWVARLTPSGALTEALVQAMTLSVDWFGLLV
Mvan_2729|M.vanbaalenii_PYR-1       LGALTLEAG----VVPSTVQWVARLTPSGALTEALTQAMTSSMDWFGLAV
MSMEG_3118|M.smegmatis_MC2_155      FGALTLETE----AVPSALAWVARLTPSGALTEALSQAMTLSVDWFGIAV
TH_0342|M.thermoresistible__bu      FGALTVEPEG--DVVPAAAALVARLTPSGALTDALSQAMTLSVNWFAVAV
Mb1492c|M.bovis_AF2122/97           FGALTLESN----VIPTAFKWVARVTPSGALTEALSQAMTVSVDWFGIVV
Rv1457c|M.tuberculosis_H37Rv        FGALTLESN----VIPTAFKWVARVTPSGALTEALSQAMTVSVDWFGIVV
MLBr_00589|M.leprae_Br4923          LGALTVKMN----MISAVVKWAARLTPSGALTEALSQAMTLSVDWFGVII
MMAR_2262|M.marinum_M               FGALTVETD----VIPTAVKWAARLTPSGALTEALSRAMVLSVDWFGVVV
MUL_1858|M.ulcerans_Agy99           FGALTVETD----VIPTAVKWAARLTPSGALTEALSRAMVLSVDWFGVVV
MAV_3322|M.avium_104                LGALTVDSG----VIPAGVKWAARLTPSGALTEALSRAMTLSADWFGMAV
MAB_2753|M.abscessus_ATCC_1997      LGALTLEDGRTTDAIPRAVVLLARLSPSGALSEALAAAMTLSVDWFAIAV
                                    :***.:.       :.      **::*****::**  **. * :**.: :

Mflv_3681|M.gilvum_PYR-GCK          LAAWGAVAALCALRWFRFV
Mvan_2729|M.vanbaalenii_PYR-1       LAVWGAVAGLCALRWFRFT
MSMEG_3118|M.smegmatis_MC2_155      LAVWGGVSAVCALRLFRFT
TH_0342|M.thermoresistible__bu      LAVWGVLGAVCALRWFRFT
Mb1492c|M.bovis_AF2122/97           LAVWGALAALAALRWFRFT
Rv1457c|M.tuberculosis_H37Rv        LAVWGALAALAALRWFRFT
MLBr_00589|M.leprae_Br4923          LTAWGTLAALAALHWFRFT
MMAR_2262|M.marinum_M               LAVWGTLAALAARRWFRFT
MUL_1858|M.ulcerans_Agy99           LAVWGTLAALAARRWFRFT
MAV_3322|M.avium_104                LVAWGALGALGALRWFRFT
MAB_2753|M.abscessus_ATCC_1997      LAVWGALAGYGALRWFKFT
                                    *..** :..  * : *:*.