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VAGHRMAAVDAQFYWMSAKVPNDQFLLYAFDGEPTDLERAVAQVYRRARGCPGLGMRVQDRGALAYPQWV PTPVQRDQLVCHDLADRSWQGCLAAVVGLASKQLDMRRMPWRLHVFTPVHDVPGVSGLGTVAVMQFAHAL GDGARASAMAAWLFGRPAAVPEIARSRAGFLPWRAAHAARAHLRLVRDTNAGLVAPGVGSRPPLSTNARP EGVRAVRTLLRRRSQLAGPTVTVTVLAAVSTGLLGLLGGDVDTLGAEVPMAKPGVPRSYNHFGNVVVGLY PRLEPDERVRRIATDLANARRRFEHPAMLSADRAFAAVPAALLRWGVSQFDAEVRPVRVAGNTVVSSVYR GAADLSFGDAPVVLTAGYPALSPAMGLTHGVHGIGDTVAISVHAAESAVSDIDAYMRLLDAALQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1125 | - | - | 100% (414) | hypothetical protein Rv1125 |
| M. tuberculosis H37Rv | Rv0221 | - | 6e-05 | 27.67% (347) | hypothetical protein Rv0221 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1156 | - | 0.0 | 99.76% (414) | hypothetical protein Mb1156 |
| M. gilvum PYR-GCK | Mflv_2109 | - | 1e-117 | 54.35% (414) | hypothetical protein Mflv_2109 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1278 | - | 2e-84 | 44.80% (433) | hypothetical protein MAB_1278 |
| M. marinum M | MMAR_4333 | - | 1e-162 | 69.49% (413) | hypothetical protein MMAR_4333 |
| M. avium 104 | MAV_1257 | - | 1e-162 | 70.34% (408) | hypothetical protein MAV_1257 |
| M. smegmatis MC2 155 | MSMEG_5205 | - | 1e-122 | 57.31% (417) | hypothetical protein MSMEG_5205 |
| M. thermoresistible (build 8) | TH_0495 | - | 4e-40 | 74.31% (109) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4596 | - | 1e-126 | 58.31% (415) | hypothetical protein Mvan_4596 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1125|M.tuberculosis_H37Rv MAGHRMAAVDAQFYWMSAKVPNDQFLLYAFDGEPTDLERAVAQVYRRARG
Mb1156|M.bovis_AF2122/97 MAGHRMAAVDAQFYWMSAKVPNDQFLLYAFDGEPTDLERAVAQVYRRARG
MMAR_4333|M.marinum_M MAAHPMAAVDAQFYWMSAKMPNDQFLLYAFDGRPAEPECAIDQLVRRARA
MAV_1257|M.avium_104 -----MAAVDAQFYWMSAKIPNDEFLLYAFDGEPADYPAAADQLRRRADA
Mflv_2109|M.gilvum_PYR-GCK MTVRRLAAVDARTYWLSRSIPDDQFLLYAFDGTADDLDEALATVADRART
Mvan_4596|M.vanbaalenii_PYR-1 MTVRRLSAVDAQTYWMSASVPSDQFLLYAFDGPVADLDRALRVVRDRAQQ
MSMEG_5205|M.smegmatis_MC2_155 --MARLAAVDAQTWWMSAKLPNDQFLLYGFDGDTGDLGAALDAVRARARR
MAB_1278|M.abscessus_ATCC_1997 MTIEQMAPRDAQMYWMSTKIPNDQFLLFCFDSPTADLDTVRSVIAARAAR
TH_0495|M.thermoresistible__bu -----MAHIRR---WGAVYI-----LILLFAG---------SWLGQFFTQ
:: * : : *: * . :
Rv1125|M.tuberculosis_H37Rv CPGLGMRVQDRG-ALAYPQWVPTPVQRDQLVCHDLADRSWQGCLAAVVGL
Mb1156|M.bovis_AF2122/97 CPGLGMRVQDRG-ALAYPQWVPTPVQRDQLVCHDLADRSWQGCLAAVVGL
MMAR_4333|M.marinum_M CPELRMRVHDGA-VLTYPRWLATDVGSEQVVRHNLDDDSWHGCLAAVVGL
MAV_1257|M.avium_104 EPALSIRVRDRG-RLRYPHWVPAAVAPEQVVRHELAEHSWDGCLAAVAGL
Mflv_2109|M.gilvum_PYR-GCK CGEFGLRIADAG-FWTYPEWAPRRVGADQFVVHAAGETAWDDCLAAVAAW
Mvan_4596|M.vanbaalenii_PYR-1 CADLGVCIEDTE-FWRYPVWAPREAGADQIVVHQLADATWQGCLSAVAGL
MSMEG_5205|M.smegmatis_MC2_155 CPDLALRISDGV-KLAYPAWVPRPVTDDQFVVHDLGAPTWNECLDAISAL
MAB_1278|M.abscessus_ATCC_1997 IADLRVRAVDVAGHLDYPYWVPRDESQLPLTVHTLADASWPQCRSAVAAL
TH_0495|M.thermoresistible__bu LAEFHSTQQQHG-----------------------QAFEWG---EYLVQF
: : * :
Rv1125|M.tuberculosis_H37Rv ASKQLDMRRMPWRLHVFTPVHDVPGVSGLGTVAVMQFAHALGDGARASAM
Mb1156|M.bovis_AF2122/97 AGKQLDMRRMPWRLHVFTPVHDVPGVSGLGTVAVMQFAHALGDGARASAM
MMAR_4333|M.marinum_M AREQLDIRLMSWRAHVFAPVSGIPGVQAPGTVVVVQVAHALGDGVRASAL
MAV_1257|M.avium_104 ADDQLDLRRMAWRLHVFGPVDGIPGVRGPGTVAVLQVAHALADGARAAAL
Mflv_2109|M.gilvum_PYR-GCK GQRQLDARAMTWRLHVFPAVVDVPGATGAAAVVVLQICHALADGVRASAL
Mvan_4596|M.vanbaalenii_PYR-1 VGEQVDPRVQTWRLHVFPAVEGLP-EAGAGSVAVLQICHALGDGIRASAL
MSMEG_5205|M.smegmatis_MC2_155 ADDQLDATTATWRLHVYPHVCDMPRNDNTGVVAVLQIAHALADGIRSSAL
MAB_1278|M.abscessus_ATCC_1997 LSSTVDIRESPWHLHLFPGVKGAPQVPGPALVAVLQVSHALADGQRSTAA
TH_0495|M.thermoresistible__bu WAATLENWQSEWLQLIFQ------------AILLLGAKHWLFR-------
:: * :: : :: * *
Rv1125|M.tuberculosis_H37Rv AAWLFGR----PAAVPEIARSR-----------AGFLPWRAAHAARAHLR
Mb1156|M.bovis_AF2122/97 AAWLFGR----PAAVPEIARSR-----------AGFLPWRAAHAARAHLR
MMAR_4333|M.marinum_M AARLFGR----RAPIPSAEPRR-----------RGFLPRVAADAVCTHRR
MAV_1257|M.avium_104 AARLFGR----AAPVPEVPVPR-----------PGWLPWRAAVAARTHRQ
Mflv_2109|M.gilvum_PYR-GCK AAYLLGR----NDPVAQVPRIRWP---------AAAFPVRAVRAGVAHRR
Mvan_4596|M.vanbaalenii_PYR-1 AAHLFGR----AGDVPALTAHRGR---------AAALPLRAFGAGRAYRR
MSMEG_5205|M.smegmatis_MC2_155 AARLFGR----ETPLDPIPASRFP---------PAALPVRAVRAARAHRR
MAB_1278|M.abscessus_ATCC_1997 ARALFGDGMPMSGSLPAVPALATVRALVGFPVKLGRLLRASRDGYRAYKR
TH_0495|M.thermoresistible__bu --------------------------------------VDAQDLERIETK
: :
Rv1125|M.tuberculosis_H37Rv LVRDTNAGLVAPGVGSRPPLSTNARPEGVRAVRTLLRRRS--QLAGPTVT
Mb1156|M.bovis_AF2122/97 LVRDTNAGLVAPGVGSRPPLSTNARPEGVRAVRTLLRRRS--QLAGPTVT
MMAR_4333|M.marinum_M LVRDTEAGLLAPGAGSRPLRSTNARPEGARELRTLVRHRS--QICGPTVT
MAV_1257|M.avium_104 LVRDTRAGRLAPGAGPRPLLPTNARPAGVRSLRTLVRHRA--QLPGPTAT
Mflv_2109|M.gilvum_PYR-GCK LVRDTDAGHVPAQAVPRPLLYSNNRPEGARHFRTVVVDRG--VFDGHTVT
Mvan_4596|M.vanbaalenii_PYR-1 LVRDTDAGMVPPQAVPRPALRSNARPAGACHLRSVVCARE--RFGGATVT
MSMEG_5205|M.smegmatis_MC2_155 LVADEASGEVPPQAPARPVLRSNSAPDGDRWIRTIVRNRN--QICGPTVT
MAB_1278|M.abscessus_ATCC_1997 QQELVSAGALEPEPQGFPLISLNARPDHRREIRMIVRPREELRAAGVSVT
TH_0495|M.thermoresistible__bu IDKLVQAGGEPAGAT---------RP------------------------
:* . *
Rv1125|M.tuberculosis_H37Rv VTVLAAVSTGLLGLL---GGDVDT-LGAEVPMAKPGVPRSYNHFGNVVVG
Mb1156|M.bovis_AF2122/97 VTVLAAVSTGLLGLL---GGDVDT-LGAEVPMAKPGVPRSYNHFGNVVVG
MMAR_4333|M.marinum_M VAVLAAVSAALSRLP---DGNAEQ-LGAEVPMAKPGLRQANNHFGNIVVG
MAV_1257|M.avium_104 VAVLGAVAQALSDLL---GDQADS-LGAEVPMAKPGAPQAYNHFGNVVVD
Mflv_2109|M.gilvum_PYR-GCK AGALSAISGALAAHLRALGDDPAH-LGAEVPMATASPRQANNHFGNVGIG
Mvan_4596|M.vanbaalenii_PYR-1 VGALAAISAALAGHLREFGEDPAQ-LGAEVPMAKAGPRLSYNHFGNVGVG
MSMEG_5205|M.smegmatis_MC2_155 VGVLSAISTALSAHLRELGDDPAD-LGAEVPMAKAGPRRARNHFGNVGIG
MAB_1278|M.abscessus_ATCC_1997 VAVMTAIAAALPRYLRDHGQWVPDRLGAEVTVAEPGESAARNNFRNVGVD
TH_0495|M.thermoresistible__bu -----------------------------VPVTPPPX-------------
*.:: .
Rv1125|M.tuberculosis_H37Rv LYPR-LEPDERVRRIATDLANARRRFEHPAMLSADRAFAAVPAALLRWGV
Mb1156|M.bovis_AF2122/97 LYPR-LEPDERVRRIATDLANARRRFEHPAMLSADRAFAAVPAALLRWGV
MMAR_4333|M.marinum_M LYPQ-LERGERMHRIAADLANARRRMQHPAASASDLAFARVPAALLRWGV
MAV_1257|M.avium_104 LHPR-LGAQARAERIAAGLAAGRRRFGHPATRAADRAFAAVPAALLRWGV
Mflv_2109|M.gilvum_PYR-GCK LHPD-AEPAHRARLIADEFAHRRRRAAHPSMRAEEAASAAVPAPLLRWGI
Mvan_4596|M.vanbaalenii_PYR-1 LYPD-RELSSRVRSIAADLHQRRRRATHPAMAAEAAALAAVPAPLLRWGV
MSMEG_5205|M.smegmatis_MC2_155 LYPD-LGHVERIEHIVEDFAQRRVRAAHPAMIAASRAFAATPAPLLRWGV
MAB_1278|M.abscessus_ATCC_1997 LCWDEPDLRVRARRIADGIESRRRRAAHPVLVAQRAGGSALPAPMMWAGV
TH_0495|M.thermoresistible__bu -----------------------XXAAHPAMRDAARAAAVVPAPLLRWGV
** . : **.:: *:
Rv1125|M.tuberculosis_H37Rv SQFDAEVRPVRVAGNTVVSSVYRGAADLSFGDAPVVLTAGYPALSPAMGL
Mb1156|M.bovis_AF2122/97 SQFDAEVRPVRVAGNTVVSSVYRGAADLSFGDAPVVLTAGYPALSPAMGL
MMAR_4333|M.marinum_M SQFDADMRPDQVAGNTVVSSVHRGAADLSFGEAPVVLTAGYPALSPVMGL
MAV_1257|M.avium_104 DQFDADQRPDQVAGNTVVSSVNRGPADLSFGGARVVLTAGYPALSPVMGL
Mflv_2109|M.gilvum_PYR-GCK SHFDPDVRSPTVNGNTVVSSVNRGAADLRFGDARVLLTAGFATLSPMMGV
Mvan_4596|M.vanbaalenii_PYR-1 GKFNPEARSSTVTGNTVVSSVNRGAKDLSFGDARVVLTTGFPGLSPMMGV
MSMEG_5205|M.smegmatis_MC2_155 AQFDPTLRSPVATGNTVVSSVNRGAADLRFGSARVAVTAGYPALSPMMGL
MAB_1278|M.abscessus_ATCC_1997 SAFDADLMPPTVAGNTVVSSVVRGAADLVLGGGRVAFTAGFPALSPVMGL
TH_0495|M.thermoresistible__bu AQFDATARSDTVTGNTVVSSVNRGAADLRFGAAPVCLTAGYPGLSPMMGL
*:. . . ******** **. ** :* . * .*:*:. *** **:
Rv1125|M.tuberculosis_H37Rv THGVHGIGDTVAISVHAAESAVS---DIDAYMRLLDAALQ-------
Mb1156|M.bovis_AF2122/97 THGVHGIGDTVAISVHAAESAVS---DIDAYMRLLDAALQ-------
MMAR_4333|M.marinum_M THGVHGIGDTIAVSVHAAQSAVA---DIDSYLELLDQAL--------
MAV_1257|M.avium_104 THGVHGIGDTIAISVHAAASAVP---DVDAYLALLDAAL--------
Mflv_2109|M.gilvum_PYR-GCK THGVHGIGERVAVSVHAAESAIG---DIDSYLDRLQEALYRPQ----
Mvan_4596|M.vanbaalenii_PYR-1 THGVHGIGDTVAVSVHAADSAIG---DIDAYLERLERELR-------
MSMEG_5205|M.smegmatis_MC2_155 THGVHGIGDTVAVSVHTAASAIGGEDALAAYVERLAKALDG------
MAB_1278|M.abscessus_ATCC_1997 THGVHGIGDTVTVSVHTSAAVLP---DADHYEALLAGALDEVSRQLR
TH_0495|M.thermoresistible__bu THGVHGIGDTVAVSVHAAAGSIG---DIDAYLARLDAALP-------
********: :::***:: . : * * *