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MTIEQMAPRDAQMYWMSTKIPNDQFLLFCFDSPTADLDTVRSVIAARAARIADLRVRAVDVAGHLDYPYW VPRDESQLPLTVHTLADASWPQCRSAVAALLSSTVDIRESPWHLHLFPGVKGAPQVPGPALVAVLQVSHA LADGQRSTAAARALFGDGMPMSGSLPAVPALATVRALVGFPVKLGRLLRASRDGYRAYKRQQELVSAGAL EPEPQGFPLISLNARPDHRREIRMIVRPREELRAAGVSVTVAVMTAIAAALPRYLRDHGQWVPDRLGAEV TVAEPGESAARNNFRNVGVDLCWDEPDLRVRARRIADGIESRRRRAAHPVLVAQRAGGSALPAPMMWAGV SAFDADLMPPTVAGNTVVSSVVRGAADLVLGGGRVAFTAGFPALSPVMGLTHGVHGIGDTVTVSVHTSAA VLPDADHYEALLAGALDEVSRQLR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1278 | - | - | 100% (444) | hypothetical protein MAB_1278 |
| M. abscessus ATCC 19977 | MAB_3551c | - | 7e-10 | 22.88% (437) | hypothetical protein MAB_3551c |
| M. abscessus ATCC 19977 | MAB_0507 | - | 4e-09 | 22.89% (402) | hypothetical protein MAB_0507 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1156 | - | 5e-84 | 44.57% (433) | hypothetical protein Mb1156 |
| M. gilvum PYR-GCK | Mflv_2109 | - | 1e-81 | 43.12% (436) | hypothetical protein Mflv_2109 |
| M. tuberculosis H37Rv | Rv1125 | - | 2e-84 | 44.80% (433) | hypothetical protein Rv1125 |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4333 | - | 1e-83 | 43.39% (431) | hypothetical protein MMAR_4333 |
| M. avium 104 | MAV_1257 | - | 1e-89 | 46.65% (433) | hypothetical protein MAV_1257 |
| M. smegmatis MC2 155 | MSMEG_5205 | - | 6e-87 | 44.70% (443) | hypothetical protein MSMEG_5205 |
| M. thermoresistible (build 8) | TH_0495 | - | 3e-28 | 56.76% (111) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1313 | - | 6e-11 | 22.93% (471) | hypothetical protein MUL_1313 |
| M. vanbaalenii PYR-1 | Mvan_4596 | - | 1e-90 | 44.59% (444) | hypothetical protein Mvan_4596 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4333|M.marinum_M MAAHPMAAVDAQFYWMSAKMPNDQFLLYAFDGRPA------EPECAIDQL
MAV_1257|M.avium_104 -----MAAVDAQFYWMSAKIPNDEFLLYAFDGEPA------DYPAAADQL
Mb1156|M.bovis_AF2122/97 MAGHRMAAVDAQFYWMSAKVPNDQFLLYAFDGEPT------DLERAVAQV
Rv1125|M.tuberculosis_H37Rv MAGHRMAAVDAQFYWMSAKVPNDQFLLYAFDGEPT------DLERAVAQV
Mflv_2109|M.gilvum_PYR-GCK MTVRRLAAVDARTYWLSRSIPDDQFLLYAFDGTAD------DLDEALATV
Mvan_4596|M.vanbaalenii_PYR-1 MTVRRLSAVDAQTYWMSASVPSDQFLLYAFDGPVA------DLDRALRVV
MSMEG_5205|M.smegmatis_MC2_155 --MARLAAVDAQTWWMSAKLPNDQFLLYGFDGDTG------DLGAALDAV
TH_0495|M.thermoresistible__bu -----MAHIRR---WGAVYI-----LILLFAG---------------SWL
MAB_1278|M.abscessus_ATCC_1997 MTIEQMAPRDAQMYWMSTKIPNDQFLLFCFDSPTA------DLDTVRSVI
MUL_1313|M.ulcerans_Agy99 --MRRLSSVDAQFFAMEDGRNHSHVCQLTIVEATTTDGLRLDGQRIRGLL
:: : :
MMAR_4333|M.marinum_M VRRARACPELRMR-VHDGAVLTYPRWLATDVGSEQVVRHNLDDDSWHG--
MAV_1257|M.avium_104 RRRADAEPALSIR-VRDRGRLRYPHWVPAAVAPEQVVRHELAEHSWDG--
Mb1156|M.bovis_AF2122/97 YRRARGCPGLGMR-VQDRGALAYPQWVPTPVQRDQLVCHDLADRSWQG--
Rv1125|M.tuberculosis_H37Rv YRRARGCPGLGMR-VQDRGALAYPQWVPTPVQRDQLVCHDLADRSWQG--
Mflv_2109|M.gilvum_PYR-GCK ADRARTCGEFGLR-IADAGFWTYPEWAPRRVGADQFVVHAAGETAWDD--
Mvan_4596|M.vanbaalenii_PYR-1 RDRAQQCADLGVC-IEDTEFWRYPVWAPREAGADQIVVHQLADATWQG--
MSMEG_5205|M.smegmatis_MC2_155 RARARRCPDLALR-ISDGVKLAYPAWVPRPVTDDQFVVHDLGAPTWNE--
TH_0495|M.thermoresistible__bu GQFFTQLAEFHST-QQQHG----------------------QAFEWGE--
MAB_1278|M.abscessus_ATCC_1997 AARAARIADLRVRAVDVAGHLDYPYWVPRDESQLPLTVHTLADASWPQ--
MUL_1313|M.ulcerans_Agy99 AQRIDLMPPLRWRVREVPFGIDYPVLVQDDTFDLDSHLWESALPAPGDDE
:
MMAR_4333|M.marinum_M -CLAAVVGLAREQLDIRLMSWRAHVFAPVSG-------------IPGVQA
MAV_1257|M.avium_104 -CLAAVAGLADDQLDLRRMAWRLHVFGPVDG-------------IPGVRG
Mb1156|M.bovis_AF2122/97 -CLAAVVGLAGKQLDMRRMPWRLHVFTPVHD-------------VPGVSG
Rv1125|M.tuberculosis_H37Rv -CLAAVVGLASKQLDMRRMPWRLHVFTPVHD-------------VPGVSG
Mflv_2109|M.gilvum_PYR-GCK -CLAAVAAWGQRQLDARAMTWRLHVFPAVVD-------------VPGATG
Mvan_4596|M.vanbaalenii_PYR-1 -CLSAVAGLVGEQVDPRVQTWRLHVFPAVEG-------------LP-EAG
MSMEG_5205|M.smegmatis_MC2_155 -CLDAISALADDQLDATTATWRLHVYPHVCD-------------MPRNDN
TH_0495|M.thermoresistible__bu -YLVQFWAAT---LENWQSEWLQLIFQ-----------------------
MAB_1278|M.abscessus_ATCC_1997 -CRSAVAALLSSTVDIRESPWHLHLFPGVKG-------------APQVPG
MUL_1313|M.ulcerans_Agy99 QLGRAVADIASRPLDRARPLWELHVIHGLAGDRVALVTKLHHSVIDGVSG
. :: * :
MMAR_4333|M.marinum_M PGTVVVVQVAHALGDG-----------------VRASALAARLFGR----
MAV_1257|M.avium_104 PGTVAVLQVAHALADG-----------------ARAAALAARLFGR----
Mb1156|M.bovis_AF2122/97 LGTVAVMQFAHALGDG-----------------ARASAMAAWLFGR----
Rv1125|M.tuberculosis_H37Rv LGTVAVMQFAHALGDG-----------------ARASAMAAWLFGR----
Mflv_2109|M.gilvum_PYR-GCK AAAVVVLQICHALADG-----------------VRASALAAYLLGR----
Mvan_4596|M.vanbaalenii_PYR-1 AGSVAVLQICHALGDG-----------------IRASALAAHLFGR----
MSMEG_5205|M.smegmatis_MC2_155 TGVVAVLQIAHALADG-----------------IRSSALAARLFGR----
TH_0495|M.thermoresistible__bu ---------------------------------------AILLLG-----
MAB_1278|M.abscessus_ATCC_1997 PALVAVLQVSHALADG-----------------QRSTAAARALFGDGMPM
MUL_1313|M.ulcerans_Agy99 MELLGALLDTVSFPDAGPELEKPPTGTAIGNASSDAGLLARALASLPVQP
* * .
MMAR_4333|M.marinum_M RAPIPSAEPRR-----------RGFLPRVAADAVCTHRRLVRDTEAGLLA
MAV_1257|M.avium_104 AAPVPEVPVPR-----------PGWLPWRAAVAARTHRQLVRDTRAGRLA
Mb1156|M.bovis_AF2122/97 PAAVPEIARSR-----------AGFLPWRAAHAARAHLRLVRDTNAGLVA
Rv1125|M.tuberculosis_H37Rv PAAVPEIARSR-----------AGFLPWRAAHAARAHLRLVRDTNAGLVA
Mflv_2109|M.gilvum_PYR-GCK NDPVAQVPRIRWP---------AAAFPVRAVRAGVAHRRLVRDTDAGHVP
Mvan_4596|M.vanbaalenii_PYR-1 AGDVPALTAHRGR---------AAALPLRAFGAGRAYRRLVRDTDAGMVP
MSMEG_5205|M.smegmatis_MC2_155 ETPLDPIPASRFP---------PAALPVRAVRAARAHRRLVADEASGEVP
TH_0495|M.thermoresistible__bu -----------------------------------AKHWLFRVDAQDLER
MAB_1278|M.abscessus_ATCC_1997 SGSLPAVPALATVRALVGFPVKLGRLLRASRDGYRAYKRQQELVSAGALE
MUL_1313|M.ulcerans_Agy99 ARMVRGLPPMLRHIDQLPTMRHLPGAAVIAKVADRAERLATRNKDGRNLQ
:
MMAR_4333|M.marinum_M PGAGSRPLRSTNARPEGARELRTLVRHRSQI-------CGPTVTVAVLAA
MAV_1257|M.avium_104 PGAGPRPLLPTNARPAGVRSLRTLVRHRAQL-------PGPTATVAVLGA
Mb1156|M.bovis_AF2122/97 PGVGSRPPLSTNARPEGVRAVRTLLRRRSQL-------AGPTVTVTVLAA
Rv1125|M.tuberculosis_H37Rv PGVGSRPPLSTNARPEGVRAVRTLLRRRSQL-------AGPTVTVTVLAA
Mflv_2109|M.gilvum_PYR-GCK AQAVPRPLLYSNNRPEGARHFRTVVVDRGVF-------DGHTVTAGALSA
Mvan_4596|M.vanbaalenii_PYR-1 PQAVPRPALRSNARPAGACHLRSVVCARERF-------GGATVTVGALAA
MSMEG_5205|M.smegmatis_MC2_155 PQAPARPVLRSNSAPDGDRWIRTIVRNRNQI-------CGPTVTVGVLSA
TH_0495|M.thermoresistible__bu IETKIDKLVQAGGEPAGATRP-----------------------------
MAB_1278|M.abscessus_ATCC_1997 PEPQGFPLISLNARPDHRREIRMIVRPREELRA-----AGVSVTVAVMTA
MUL_1313|M.ulcerans_Agy99 HPRAAAPKVSFGGRISAQRRFAFGSLPLDQIKAAKFAVPGATVNDVVVAV
.
MMAR_4333|M.marinum_M VSAALSRLP----DGNAEQLGAEVPMAKPGLRQAN-NHFGNIVVGL-YPQ
MAV_1257|M.avium_104 VAQALSDLL----GDQADSLGAEVPMAKPGAPQAY-NHFGNVVVDL-HPR
Mb1156|M.bovis_AF2122/97 VSTGLLGLL----GGDVDTLGAEVPMAKPGVPRSY-NHFGNVVVGL-YPR
Rv1125|M.tuberculosis_H37Rv VSTGLLGLL----GGDVDTLGAEVPMAKPGVPRSY-NHFGNVVVGL-YPR
Mflv_2109|M.gilvum_PYR-GCK ISGALAAHLRAL-GDDPAHLGAEVPMATASPRQAN-NHFGNVGIGL-HPD
Mvan_4596|M.vanbaalenii_PYR-1 ISAALAGHLREF-GEDPAQLGAEVPMAKAGPRLSY-NHFGNVGVGL-YPD
MSMEG_5205|M.smegmatis_MC2_155 ISTALSAHLREL-GDDPADLGAEVPMAKAGPRRAR-NHFGNVGIGL-YPD
TH_0495|M.thermoresistible__bu -----------------------VPVTPP-------------------PX
MAB_1278|M.abscessus_ATCC_1997 IAAALPRYLRDHGQWVPDRLGAEVTVAEPGESAAR-NNFRNVGVDLCWDE
MUL_1313|M.ulcerans_Agy99 CAGALRRRMIARGDDVATPLVAMVPVSVRTGERQYGNQISSMIVPIPTDQ
*.::
MMAR_4333|M.marinum_M LERGERMHRIAADLANARRRMQHPAASASDLAFARVPAALLRWGVSQFDA
MAV_1257|M.avium_104 LGAQARAERIAAGLAAGRRRFGHPATRAADRAFAAVPAALLRWGVDQFDA
Mb1156|M.bovis_AF2122/97 LEPDERVRRIATDLANARRRFEHPAMLSADRAFAAVPAALLRWGVSQFDA
Rv1125|M.tuberculosis_H37Rv LEPDERVRRIATDLANARRRFEHPAMLSADRAFAAVPAALLRWGVSQFDA
Mflv_2109|M.gilvum_PYR-GCK AEPAHRARLIADEFAHRRRRAAHPSMRAEEAASAAVPAPLLRWGISHFDP
Mvan_4596|M.vanbaalenii_PYR-1 RELSSRVRSIAADLHQRRRRATHPAMAAEAAALAAVPAPLLRWGVGKFNP
MSMEG_5205|M.smegmatis_MC2_155 LGHVERIEHIVEDFAQRRVRAAHPAMIAASRAFAATPAPLLRWGVAQFDP
TH_0495|M.thermoresistible__bu X------------------XAAHPAMRDAARAAAVVPAPLLRWGVAQFDA
MAB_1278|M.abscessus_ATCC_1997 PDLRVRARRIADGIESRRRRAAHPVLVAQRAGGSALPAPMMWAGVSAFDA
MUL_1313|M.ulcerans_Agy99 ADARARLISAHQVMRAAKERHRAIPAKLLTEANHTVPPALLTRAARVISM
. *..:: . :.
MMAR_4333|M.marinum_M DMRPDQVAG--NTVVSSVHRGAADLSFGEAPVVLTAGYPALSPVMGLTHG
MAV_1257|M.avium_104 DQRPDQVAG--NTVVSSVNRGPADLSFGGARVVLTAGYPALSPVMGLTHG
Mb1156|M.bovis_AF2122/97 EVRPVRVAG--NTVVSSVYRGAADLSFGDAPVVLTAGYPALSPAMGLTHG
Rv1125|M.tuberculosis_H37Rv EVRPVRVAG--NTVVSSVYRGAADLSFGDAPVVLTAGYPALSPAMGLTHG
Mflv_2109|M.gilvum_PYR-GCK DVRSPTVNG--NTVVSSVNRGAADLRFGDARVLLTAGFATLSPMMGVTHG
Mvan_4596|M.vanbaalenii_PYR-1 EARSSTVTG--NTVVSSVNRGAKDLSFGDARVVLTTGFPGLSPMMGVTHG
MSMEG_5205|M.smegmatis_MC2_155 TLRSPVATG--NTVVSSVNRGAADLRFGSARVAVTAGYPALSPMMGLTHG
TH_0495|M.thermoresistible__bu TARSDTVTG--NTVVSSVNRGAADLRFGAAPVCLTAGYPGLSPMMGLTHG
MAB_1278|M.abscessus_ATCC_1997 DLMPPTVAG--NTVVSSVVRGAADLVLGGGRVAFTAGFPALSPVMGLTHG
MUL_1313|M.ulcerans_Agy99 TTGSGWIRPPFNVTISNIPGSPDPLYCAGARVVSQHPVNVLLDGMGLSIT
. *..:*.: .. * . . * * **::
MMAR_4333|M.marinum_M VHGIGDTIAVSVHAAQSAVA---DIDSYLELLDQAL--------------
MAV_1257|M.avium_104 VHGIGDTIAISVHAAASAVP---DVDAYLALLDAAL--------------
Mb1156|M.bovis_AF2122/97 VHGIGDTVAISVHAAESAVS---DIDAYMRLLDAALQ-------------
Rv1125|M.tuberculosis_H37Rv VHGIGDTVAISVHAAESAVS---DIDAYMRLLDAALQ-------------
Mflv_2109|M.gilvum_PYR-GCK VHGIGERVAVSVHAAESAIG---DIDSYLDRLQEALYRPQ----------
Mvan_4596|M.vanbaalenii_PYR-1 VHGIGDTVAVSVHAADSAIG---DIDAYLERLERELR-------------
MSMEG_5205|M.smegmatis_MC2_155 VHGIGDTVAVSVHTAASAIGGEDALAAYVERLAKALDG------------
TH_0495|M.thermoresistible__bu VHGIGDTVAVSVHAAAGSIG---DIDAYLARLDAALP-------------
MAB_1278|M.abscessus_ATCC_1997 VHGIGDTVTVSVHTSAAVLP---DADHYEALLAGALDEVSRQLR------
MUL_1313|M.ulcerans_Agy99 LLSYQDRLDFGLTADRELLP---DVWHLADELAAELSALAAEVGAPRNPV
: . : : ..: : : * *
MMAR_4333|M.marinum_M ---------------------
MAV_1257|M.avium_104 ---------------------
Mb1156|M.bovis_AF2122/97 ---------------------
Rv1125|M.tuberculosis_H37Rv ---------------------
Mflv_2109|M.gilvum_PYR-GCK ---------------------
Mvan_4596|M.vanbaalenii_PYR-1 ---------------------
MSMEG_5205|M.smegmatis_MC2_155 ---------------------
TH_0495|M.thermoresistible__bu ---------------------
MAB_1278|M.abscessus_ATCC_1997 ---------------------
MUL_1313|M.ulcerans_Agy99 ADGAPTSTTGRPTAKPGAIPR