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MAAVDAQFYWMSAKIPNDEFLLYAFDGEPADYPAAADQLRRRADAEPALSIRVRDRGRLRYPHWVPAAVA PEQVVRHELAEHSWDGCLAAVAGLADDQLDLRRMAWRLHVFGPVDGIPGVRGPGTVAVLQVAHALADGAR AAALAARLFGRAAPVPEVPVPRPGWLPWRAAVAARTHRQLVRDTRAGRLAPGAGPRPLLPTNARPAGVRS LRTLVRHRAQLPGPTATVAVLGAVAQALSDLLGDQADSLGAEVPMAKPGAPQAYNHFGNVVVDLHPRLGA QARAERIAAGLAAGRRRFGHPATRAADRAFAAVPAALLRWGVDQFDADQRPDQVAGNTVVSSVNRGPADL SFGGARVVLTAGYPALSPVMGLTHGVHGIGDTIAISVHAAASAVPDVDAYLALLDAAL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1257 | - | - | 100% (408) | hypothetical protein MAV_1257 |
| M. avium 104 | MAV_3015 | - | 4e-07 | 27.12% (424) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. avium 104 | MAV_1847 | - | 4e-05 | 28.08% (317) | acyltransferase, ws/dgat/mgat subfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1156 | - | 1e-162 | 70.34% (408) | hypothetical protein Mb1156 |
| M. gilvum PYR-GCK | Mflv_2109 | - | 1e-109 | 52.77% (415) | hypothetical protein Mflv_2109 |
| M. tuberculosis H37Rv | Rv1125 | - | 1e-162 | 70.34% (408) | hypothetical protein Rv1125 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1278 | - | 1e-89 | 46.65% (433) | hypothetical protein MAB_1278 |
| M. marinum M | MMAR_4333 | - | 1e-158 | 70.59% (408) | hypothetical protein MMAR_4333 |
| M. smegmatis MC2 155 | MSMEG_5205 | - | 1e-121 | 56.34% (410) | hypothetical protein MSMEG_5205 |
| M. thermoresistible (build 8) | TH_0495 | - | 3e-41 | 75.23% (109) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1313 | - | 2e-06 | 24.30% (395) | hypothetical protein MUL_1313 |
| M. vanbaalenii PYR-1 | Mvan_4596 | - | 1e-116 | 54.72% (413) | hypothetical protein Mvan_4596 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2109|M.gilvum_PYR-GCK MTVRRLAAVDARTYWLSRSIPDDQFLLYAFDGTAD------DLDEALATV
Mvan_4596|M.vanbaalenii_PYR-1 MTVRRLSAVDAQTYWMSASVPSDQFLLYAFDGPVA------DLDRALRVV
MSMEG_5205|M.smegmatis_MC2_155 --MARLAAVDAQTWWMSAKLPNDQFLLYGFDGDTG------DLGAALDAV
Mb1156|M.bovis_AF2122/97 MAGHRMAAVDAQFYWMSAKVPNDQFLLYAFDGEPT------DLERAVAQV
Rv1125|M.tuberculosis_H37Rv MAGHRMAAVDAQFYWMSAKVPNDQFLLYAFDGEPT------DLERAVAQV
MAV_1257|M.avium_104 -----MAAVDAQFYWMSAKIPNDEFLLYAFDGEPA------DYPAAADQL
MMAR_4333|M.marinum_M MAAHPMAAVDAQFYWMSAKMPNDQFLLYAFDGRPA------EPECAIDQL
TH_0495|M.thermoresistible__bu -----MAHIRR---WGAVYI-----LILLFAG---------------SWL
MAB_1278|M.abscessus_ATCC_1997 MTIEQMAPRDAQMYWMSTKIPNDQFLLFCFDSPTA------DLDTVRSVI
MUL_1313|M.ulcerans_Agy99 --MRRLSSVDAQFFAMEDGRNHSHVCQLTIVEATTTDGLRLDGQRIRGLL
:: : :
Mflv_2109|M.gilvum_PYR-GCK ADRARTCGEFGLR-IADAGFWTYPEWAPRRVGADQFVVHAAGETAWDD--
Mvan_4596|M.vanbaalenii_PYR-1 RDRAQQCADLGVC-IEDTEFWRYPVWAPREAGADQIVVHQLADATWQG--
MSMEG_5205|M.smegmatis_MC2_155 RARARRCPDLALR-ISDGVKLAYPAWVPRPVTDDQFVVHDLGAPTWNE--
Mb1156|M.bovis_AF2122/97 YRRARGCPGLGMR-VQDRGALAYPQWVPTPVQRDQLVCHDLADRSWQG--
Rv1125|M.tuberculosis_H37Rv YRRARGCPGLGMR-VQDRGALAYPQWVPTPVQRDQLVCHDLADRSWQG--
MAV_1257|M.avium_104 RRRADAEPALSIR-VRDRGRLRYPHWVPAAVAPEQVVRHELAEHSWDG--
MMAR_4333|M.marinum_M VRRARACPELRMR-VHDGAVLTYPRWLATDVGSEQVVRHNLDDDSWHG--
TH_0495|M.thermoresistible__bu GQFFTQLAEFHST-QQQHG----------------------QAFEWGE--
MAB_1278|M.abscessus_ATCC_1997 AARAARIADLRVRAVDVAGHLDYPYWVPRDESQLPLTVHTLADASWPQ--
MUL_1313|M.ulcerans_Agy99 AQRIDLMPPLRWRVREVPFGIDYPVLVQDDTFDLDSHLWESALPAPGDDE
:
Mflv_2109|M.gilvum_PYR-GCK -CLAAVAAWGQRQLDARAMTWRLHVFPAVVD-------------VPGATG
Mvan_4596|M.vanbaalenii_PYR-1 -CLSAVAGLVGEQVDPRVQTWRLHVFPAVEG-------------LP-EAG
MSMEG_5205|M.smegmatis_MC2_155 -CLDAISALADDQLDATTATWRLHVYPHVCD-------------MPRNDN
Mb1156|M.bovis_AF2122/97 -CLAAVVGLAGKQLDMRRMPWRLHVFTPVHD-------------VPGVSG
Rv1125|M.tuberculosis_H37Rv -CLAAVVGLASKQLDMRRMPWRLHVFTPVHD-------------VPGVSG
MAV_1257|M.avium_104 -CLAAVAGLADDQLDLRRMAWRLHVFGPVDG-------------IPGVRG
MMAR_4333|M.marinum_M -CLAAVVGLAREQLDIRLMSWRAHVFAPVSG-------------IPGVQA
TH_0495|M.thermoresistible__bu -YLVQFWAAT---LENWQSEWLQLIFQ-----------------------
MAB_1278|M.abscessus_ATCC_1997 -CRSAVAALLSSTVDIRESPWHLHLFPGVKG-------------APQVPG
MUL_1313|M.ulcerans_Agy99 QLGRAVADIASRPLDRARPLWELHVIHGLAGDRVALVTKLHHSVIDGVSG
. :: * :
Mflv_2109|M.gilvum_PYR-GCK AAAVVVLQICHALADG-----------------VRASALAAYLLGR----
Mvan_4596|M.vanbaalenii_PYR-1 AGSVAVLQICHALGDG-----------------IRASALAAHLFGR----
MSMEG_5205|M.smegmatis_MC2_155 TGVVAVLQIAHALADG-----------------IRSSALAARLFGR----
Mb1156|M.bovis_AF2122/97 LGTVAVMQFAHALGDG-----------------ARASAMAAWLFGR----
Rv1125|M.tuberculosis_H37Rv LGTVAVMQFAHALGDG-----------------ARASAMAAWLFGR----
MAV_1257|M.avium_104 PGTVAVLQVAHALADG-----------------ARAAALAARLFGR----
MMAR_4333|M.marinum_M PGTVVVVQVAHALGDG-----------------VRASALAARLFGR----
TH_0495|M.thermoresistible__bu ---------------------------------------AILLLG-----
MAB_1278|M.abscessus_ATCC_1997 PALVAVLQVSHALADG-----------------QRSTAAARALFGDGMPM
MUL_1313|M.ulcerans_Agy99 MELLGALLDTVSFPDAGPELEKPPTGTAIGNASSDAGLLARALASLPVQP
* * .
Mflv_2109|M.gilvum_PYR-GCK NDPVAQVPRIRWP---------AAAFPVRAVRAGVAHRRLVRDTDAGHVP
Mvan_4596|M.vanbaalenii_PYR-1 AGDVPALTAHRGR---------AAALPLRAFGAGRAYRRLVRDTDAGMVP
MSMEG_5205|M.smegmatis_MC2_155 ETPLDPIPASRFP---------PAALPVRAVRAARAHRRLVADEASGEVP
Mb1156|M.bovis_AF2122/97 PAAVPEIARSR-----------AGFLPWRAAHAARAHLRLVRDTNAGLVA
Rv1125|M.tuberculosis_H37Rv PAAVPEIARSR-----------AGFLPWRAAHAARAHLRLVRDTNAGLVA
MAV_1257|M.avium_104 AAPVPEVPVPR-----------PGWLPWRAAVAARTHRQLVRDTRAGRLA
MMAR_4333|M.marinum_M RAPIPSAEPRR-----------RGFLPRVAADAVCTHRRLVRDTEAGLLA
TH_0495|M.thermoresistible__bu -----------------------------------AKHWLFRVDAQDLER
MAB_1278|M.abscessus_ATCC_1997 SGSLPAVPALATVRALVGFPVKLGRLLRASRDGYRAYKRQQELVSAGALE
MUL_1313|M.ulcerans_Agy99 ARMVRGLPPMLRHIDQLPTMRHLPGAAVIAKVADRAERLATRNKDGRNLQ
:
Mflv_2109|M.gilvum_PYR-GCK AQAVPRPLLYSNNRPEGARHFRTVVVDRGVF-------DGHTVTAGALSA
Mvan_4596|M.vanbaalenii_PYR-1 PQAVPRPALRSNARPAGACHLRSVVCARERF-------GGATVTVGALAA
MSMEG_5205|M.smegmatis_MC2_155 PQAPARPVLRSNSAPDGDRWIRTIVRNRNQI-------CGPTVTVGVLSA
Mb1156|M.bovis_AF2122/97 PGVGSRPPLSTNARPEGVRAVRTLLRRRSQL-------AGPTVTVTVLAA
Rv1125|M.tuberculosis_H37Rv PGVGSRPPLSTNARPEGVRAVRTLLRRRSQL-------AGPTVTVTVLAA
MAV_1257|M.avium_104 PGAGPRPLLPTNARPAGVRSLRTLVRHRAQL-------PGPTATVAVLGA
MMAR_4333|M.marinum_M PGAGSRPLRSTNARPEGARELRTLVRHRSQI-------CGPTVTVAVLAA
TH_0495|M.thermoresistible__bu IETKIDKLVQAGGEPAGATRP-----------------------------
MAB_1278|M.abscessus_ATCC_1997 PEPQGFPLISLNARPDHRREIRMIVRPREELRA-----AGVSVTVAVMTA
MUL_1313|M.ulcerans_Agy99 HPRAAAPKVSFGGRISAQRRFAFGSLPLDQIKAAKFAVPGATVNDVVVAV
.
Mflv_2109|M.gilvum_PYR-GCK ISGALAAHLRAL-GDDPAHLGAEVPMATASPRQAN-NHFGNVGIGL-HPD
Mvan_4596|M.vanbaalenii_PYR-1 ISAALAGHLREF-GEDPAQLGAEVPMAKAGPRLSY-NHFGNVGVGL-YPD
MSMEG_5205|M.smegmatis_MC2_155 ISTALSAHLREL-GDDPADLGAEVPMAKAGPRRAR-NHFGNVGIGL-YPD
Mb1156|M.bovis_AF2122/97 VSTGLLGLL----GGDVDTLGAEVPMAKPGVPRSY-NHFGNVVVGL-YPR
Rv1125|M.tuberculosis_H37Rv VSTGLLGLL----GGDVDTLGAEVPMAKPGVPRSY-NHFGNVVVGL-YPR
MAV_1257|M.avium_104 VAQALSDLL----GDQADSLGAEVPMAKPGAPQAY-NHFGNVVVDL-HPR
MMAR_4333|M.marinum_M VSAALSRLP----DGNAEQLGAEVPMAKPGLRQAN-NHFGNIVVGL-YPQ
TH_0495|M.thermoresistible__bu -----------------------VPVTPP-------------------PX
MAB_1278|M.abscessus_ATCC_1997 IAAALPRYLRDHGQWVPDRLGAEVTVAEPGESAAR-NNFRNVGVDLCWDE
MUL_1313|M.ulcerans_Agy99 CAGALRRRMIARGDDVATPLVAMVPVSVRTGERQYGNQISSMIVPIPTDQ
*.::
Mflv_2109|M.gilvum_PYR-GCK AEPAHRARLIADEFAHRRRRAAHPSMRAEEAASAAVPAPLLRWGISHFDP
Mvan_4596|M.vanbaalenii_PYR-1 RELSSRVRSIAADLHQRRRRATHPAMAAEAAALAAVPAPLLRWGVGKFNP
MSMEG_5205|M.smegmatis_MC2_155 LGHVERIEHIVEDFAQRRVRAAHPAMIAASRAFAATPAPLLRWGVAQFDP
Mb1156|M.bovis_AF2122/97 LEPDERVRRIATDLANARRRFEHPAMLSADRAFAAVPAALLRWGVSQFDA
Rv1125|M.tuberculosis_H37Rv LEPDERVRRIATDLANARRRFEHPAMLSADRAFAAVPAALLRWGVSQFDA
MAV_1257|M.avium_104 LGAQARAERIAAGLAAGRRRFGHPATRAADRAFAAVPAALLRWGVDQFDA
MMAR_4333|M.marinum_M LERGERMHRIAADLANARRRMQHPAASASDLAFARVPAALLRWGVSQFDA
TH_0495|M.thermoresistible__bu X------------------XAAHPAMRDAARAAAVVPAPLLRWGVAQFDA
MAB_1278|M.abscessus_ATCC_1997 PDLRVRARRIADGIESRRRRAAHPVLVAQRAGGSALPAPMMWAGVSAFDA
MUL_1313|M.ulcerans_Agy99 ADARARLISAHQVMRAAKERHRAIPAKLLTEANHTVPPALLTRAARVISM
. *..:: . :.
Mflv_2109|M.gilvum_PYR-GCK DVRSPTVNG--NTVVSSVNRGAADLRFGDARVLLTAGFATLSPMMGVTHG
Mvan_4596|M.vanbaalenii_PYR-1 EARSSTVTG--NTVVSSVNRGAKDLSFGDARVVLTTGFPGLSPMMGVTHG
MSMEG_5205|M.smegmatis_MC2_155 TLRSPVATG--NTVVSSVNRGAADLRFGSARVAVTAGYPALSPMMGLTHG
Mb1156|M.bovis_AF2122/97 EVRPVRVAG--NTVVSSVYRGAADLSFGDAPVVLTAGYPALSPAMGLTHG
Rv1125|M.tuberculosis_H37Rv EVRPVRVAG--NTVVSSVYRGAADLSFGDAPVVLTAGYPALSPAMGLTHG
MAV_1257|M.avium_104 DQRPDQVAG--NTVVSSVNRGPADLSFGGARVVLTAGYPALSPVMGLTHG
MMAR_4333|M.marinum_M DMRPDQVAG--NTVVSSVHRGAADLSFGEAPVVLTAGYPALSPVMGLTHG
TH_0495|M.thermoresistible__bu TARSDTVTG--NTVVSSVNRGAADLRFGAAPVCLTAGYPGLSPMMGLTHG
MAB_1278|M.abscessus_ATCC_1997 DLMPPTVAG--NTVVSSVVRGAADLVLGGGRVAFTAGFPALSPVMGLTHG
MUL_1313|M.ulcerans_Agy99 TTGSGWIRPPFNVTISNIPGSPDPLYCAGARVVSQHPVNVLLDGMGLSIT
. *..:*.: .. * . . * * **::
Mflv_2109|M.gilvum_PYR-GCK VHGIGERVAVSVHAAESAIG---DIDSYLDRLQEALYRPQ----------
Mvan_4596|M.vanbaalenii_PYR-1 VHGIGDTVAVSVHAADSAIG---DIDAYLERLERELR-------------
MSMEG_5205|M.smegmatis_MC2_155 VHGIGDTVAVSVHTAASAIGGEDALAAYVERLAKALDG------------
Mb1156|M.bovis_AF2122/97 VHGIGDTVAISVHAAESAVS---DIDAYMRLLDAALQ-------------
Rv1125|M.tuberculosis_H37Rv VHGIGDTVAISVHAAESAVS---DIDAYMRLLDAALQ-------------
MAV_1257|M.avium_104 VHGIGDTIAISVHAAASAVP---DVDAYLALLDAAL--------------
MMAR_4333|M.marinum_M VHGIGDTIAVSVHAAQSAVA---DIDSYLELLDQAL--------------
TH_0495|M.thermoresistible__bu VHGIGDTVAVSVHAAAGSIG---DIDAYLARLDAALP-------------
MAB_1278|M.abscessus_ATCC_1997 VHGIGDTVTVSVHTSAAVLP---DADHYEALLAGALDEVSRQLR------
MUL_1313|M.ulcerans_Agy99 LLSYQDRLDFGLTADRELLP---DVWHLADELAAELSALAAEVGAPRNPV
: . : : ..: : : * *
Mflv_2109|M.gilvum_PYR-GCK ---------------------
Mvan_4596|M.vanbaalenii_PYR-1 ---------------------
MSMEG_5205|M.smegmatis_MC2_155 ---------------------
Mb1156|M.bovis_AF2122/97 ---------------------
Rv1125|M.tuberculosis_H37Rv ---------------------
MAV_1257|M.avium_104 ---------------------
MMAR_4333|M.marinum_M ---------------------
TH_0495|M.thermoresistible__bu ---------------------
MAB_1278|M.abscessus_ATCC_1997 ---------------------
MUL_1313|M.ulcerans_Agy99 ADGAPTSTTGRPTAKPGAIPR