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TVRRLSAVDAQTYWMSASVPSDQFLLYAFDGPVADLDRALRVVRDRAQQCADLGVCIEDTEFWRYPVWAP REAGADQIVVHQLADATWQGCLSAVAGLVGEQVDPRVQTWRLHVFPAVEGLPEAGAGSVAVLQICHALGD GIRASALAAHLFGRAGDVPALTAHRGRAAALPLRAFGAGRAYRRLVRDTDAGMVPPQAVPRPALRSNARP AGACHLRSVVCARERFGGATVTVGALAAISAALAGHLREFGEDPAQLGAEVPMAKAGPRLSYNHFGNVGV GLYPDRELSSRVRSIAADLHQRRRRATHPAMAAEAAALAAVPAPLLRWGVGKFNPEARSSTVTGNTVVSS VNRGAKDLSFGDARVVLTTGFPGLSPMMGVTHGVHGIGDTVAVSVHAADSAIGDIDAYLERLERELR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4596 | - | - | 100% (418) | hypothetical protein Mvan_4596 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1156 | - | 1e-127 | 58.55% (415) | hypothetical protein Mb1156 |
| M. gilvum PYR-GCK | Mflv_2109 | - | 1e-152 | 65.79% (418) | hypothetical protein Mflv_2109 |
| M. tuberculosis H37Rv | Rv1125 | - | 1e-126 | 58.31% (415) | hypothetical protein Rv1125 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1278 | - | 8e-91 | 44.59% (444) | hypothetical protein MAB_1278 |
| M. marinum M | MMAR_4333 | - | 1e-118 | 54.96% (413) | hypothetical protein MMAR_4333 |
| M. avium 104 | MAV_1257 | - | 1e-116 | 54.72% (413) | hypothetical protein MAV_1257 |
| M. smegmatis MC2 155 | MSMEG_5205 | - | 1e-134 | 59.90% (419) | hypothetical protein MSMEG_5205 |
| M. thermoresistible (build 8) | TH_0495 | - | 2e-41 | 74.77% (111) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4596|M.vanbaalenii_PYR-1 MTVRRLSAVDAQTYWMSASVPSDQFLLYAFDGPVADLDRALRVVRDRAQQ
Mflv_2109|M.gilvum_PYR-GCK MTVRRLAAVDARTYWLSRSIPDDQFLLYAFDGTADDLDEALATVADRART
MSMEG_5205|M.smegmatis_MC2_155 --MARLAAVDAQTWWMSAKLPNDQFLLYGFDGDTGDLGAALDAVRARARR
Mb1156|M.bovis_AF2122/97 MAGHRMAAVDAQFYWMSAKVPNDQFLLYAFDGEPTDLERAVAQVYRRARG
Rv1125|M.tuberculosis_H37Rv MAGHRMAAVDAQFYWMSAKVPNDQFLLYAFDGEPTDLERAVAQVYRRARG
MMAR_4333|M.marinum_M MAAHPMAAVDAQFYWMSAKMPNDQFLLYAFDGRPAEPECAIDQLVRRARA
MAV_1257|M.avium_104 -----MAAVDAQFYWMSAKIPNDEFLLYAFDGEPADYPAAADQLRRRADA
MAB_1278|M.abscessus_ATCC_1997 MTIEQMAPRDAQMYWMSTKIPNDQFLLFCFDSPTADLDTVRSVIAARAAR
TH_0495|M.thermoresistible__bu -----MAHIRR---WGAVYI-----LILLFAG---------SWLGQFFTQ
:: * : : *: * . :
Mvan_4596|M.vanbaalenii_PYR-1 CADLGVCIEDTE-FWRYPVWAPREAGADQIVVHQLADATWQGCLSAVAGL
Mflv_2109|M.gilvum_PYR-GCK CGEFGLRIADAG-FWTYPEWAPRRVGADQFVVHAAGETAWDDCLAAVAAW
MSMEG_5205|M.smegmatis_MC2_155 CPDLALRISDGV-KLAYPAWVPRPVTDDQFVVHDLGAPTWNECLDAISAL
Mb1156|M.bovis_AF2122/97 CPGLGMRVQDRG-ALAYPQWVPTPVQRDQLVCHDLADRSWQGCLAAVVGL
Rv1125|M.tuberculosis_H37Rv CPGLGMRVQDRG-ALAYPQWVPTPVQRDQLVCHDLADRSWQGCLAAVVGL
MMAR_4333|M.marinum_M CPELRMRVHDGA-VLTYPRWLATDVGSEQVVRHNLDDDSWHGCLAAVVGL
MAV_1257|M.avium_104 EPALSIRVRDRG-RLRYPHWVPAAVAPEQVVRHELAEHSWDGCLAAVAGL
MAB_1278|M.abscessus_ATCC_1997 IADLRVRAVDVAGHLDYPYWVPRDESQLPLTVHTLADASWPQCRSAVAAL
TH_0495|M.thermoresistible__bu LAEFHSTQQQHG-----------------------QAFEWG---EYLVQF
: : * :
Mvan_4596|M.vanbaalenii_PYR-1 VGEQVDPRVQTWRLHVFPAVEGLP-EAGAGSVAVLQICHALGDGIRASAL
Mflv_2109|M.gilvum_PYR-GCK GQRQLDARAMTWRLHVFPAVVDVPGATGAAAVVVLQICHALADGVRASAL
MSMEG_5205|M.smegmatis_MC2_155 ADDQLDATTATWRLHVYPHVCDMPRNDNTGVVAVLQIAHALADGIRSSAL
Mb1156|M.bovis_AF2122/97 AGKQLDMRRMPWRLHVFTPVHDVPGVSGLGTVAVMQFAHALGDGARASAM
Rv1125|M.tuberculosis_H37Rv ASKQLDMRRMPWRLHVFTPVHDVPGVSGLGTVAVMQFAHALGDGARASAM
MMAR_4333|M.marinum_M AREQLDIRLMSWRAHVFAPVSGIPGVQAPGTVVVVQVAHALGDGVRASAL
MAV_1257|M.avium_104 ADDQLDLRRMAWRLHVFGPVDGIPGVRGPGTVAVLQVAHALADGARAAAL
MAB_1278|M.abscessus_ATCC_1997 LSSTVDIRESPWHLHLFPGVKGAPQVPGPALVAVLQVSHALADGQRSTAA
TH_0495|M.thermoresistible__bu WAATLENWQSEWLQLIFQ------------AILLLGAKHWLFR-------
:: * :: : :: * *
Mvan_4596|M.vanbaalenii_PYR-1 AAHLFGR----AGDVPALTAHRGR---------AAALPLRAFGAGRAYRR
Mflv_2109|M.gilvum_PYR-GCK AAYLLGR----NDPVAQVPRIRWP---------AAAFPVRAVRAGVAHRR
MSMEG_5205|M.smegmatis_MC2_155 AARLFGR----ETPLDPIPASRFP---------PAALPVRAVRAARAHRR
Mb1156|M.bovis_AF2122/97 AAWLFGR----PAAVPEIARSR-----------AGFLPWRAAHAARAHLR
Rv1125|M.tuberculosis_H37Rv AAWLFGR----PAAVPEIARSR-----------AGFLPWRAAHAARAHLR
MMAR_4333|M.marinum_M AARLFGR----RAPIPSAEPRR-----------RGFLPRVAADAVCTHRR
MAV_1257|M.avium_104 AARLFGR----AAPVPEVPVPR-----------PGWLPWRAAVAARTHRQ
MAB_1278|M.abscessus_ATCC_1997 ARALFGDGMPMSGSLPAVPALATVRALVGFPVKLGRLLRASRDGYRAYKR
TH_0495|M.thermoresistible__bu --------------------------------------VDAQDLERIETK
: :
Mvan_4596|M.vanbaalenii_PYR-1 LVRDTDAGMVPPQAVPRPALRSNARPAGACHLRSVVCARE--RFGGATVT
Mflv_2109|M.gilvum_PYR-GCK LVRDTDAGHVPAQAVPRPLLYSNNRPEGARHFRTVVVDRG--VFDGHTVT
MSMEG_5205|M.smegmatis_MC2_155 LVADEASGEVPPQAPARPVLRSNSAPDGDRWIRTIVRNRN--QICGPTVT
Mb1156|M.bovis_AF2122/97 LVRDTNAGLVAPGVGSRPPLSTNARPEGVRAVRTLLRRRS--QLAGPTVT
Rv1125|M.tuberculosis_H37Rv LVRDTNAGLVAPGVGSRPPLSTNARPEGVRAVRTLLRRRS--QLAGPTVT
MMAR_4333|M.marinum_M LVRDTEAGLLAPGAGSRPLRSTNARPEGARELRTLVRHRS--QICGPTVT
MAV_1257|M.avium_104 LVRDTRAGRLAPGAGPRPLLPTNARPAGVRSLRTLVRHRA--QLPGPTAT
MAB_1278|M.abscessus_ATCC_1997 QQELVSAGALEPEPQGFPLISLNARPDHRREIRMIVRPREELRAAGVSVT
TH_0495|M.thermoresistible__bu IDKLVQAGGEPAGAT---------RP------------------------
:* . *
Mvan_4596|M.vanbaalenii_PYR-1 VGALAAISAALAGHLREFGEDPAQ-LGAEVPMAKAGPRLSYNHFGNVGVG
Mflv_2109|M.gilvum_PYR-GCK AGALSAISGALAAHLRALGDDPAH-LGAEVPMATASPRQANNHFGNVGIG
MSMEG_5205|M.smegmatis_MC2_155 VGVLSAISTALSAHLRELGDDPAD-LGAEVPMAKAGPRRARNHFGNVGIG
Mb1156|M.bovis_AF2122/97 VTVLAAVSTGLLGLL---GGDVDT-LGAEVPMAKPGVPRSYNHFGNVVVG
Rv1125|M.tuberculosis_H37Rv VTVLAAVSTGLLGLL---GGDVDT-LGAEVPMAKPGVPRSYNHFGNVVVG
MMAR_4333|M.marinum_M VAVLAAVSAALSRLP---DGNAEQ-LGAEVPMAKPGLRQANNHFGNIVVG
MAV_1257|M.avium_104 VAVLGAVAQALSDLL---GDQADS-LGAEVPMAKPGAPQAYNHFGNVVVD
MAB_1278|M.abscessus_ATCC_1997 VAVMTAIAAALPRYLRDHGQWVPDRLGAEVTVAEPGESAARNNFRNVGVD
TH_0495|M.thermoresistible__bu -----------------------------VPVTPPPX-------------
*.:: .
Mvan_4596|M.vanbaalenii_PYR-1 LYPD-RELSSRVRSIAADLHQRRRRATHPAMAAEAAALAAVPAPLLRWGV
Mflv_2109|M.gilvum_PYR-GCK LHPD-AEPAHRARLIADEFAHRRRRAAHPSMRAEEAASAAVPAPLLRWGI
MSMEG_5205|M.smegmatis_MC2_155 LYPD-LGHVERIEHIVEDFAQRRVRAAHPAMIAASRAFAATPAPLLRWGV
Mb1156|M.bovis_AF2122/97 LYPR-LEPDERVRRIATDLANARRRFEHPAMLSADRAFAAVPAALLRWGV
Rv1125|M.tuberculosis_H37Rv LYPR-LEPDERVRRIATDLANARRRFEHPAMLSADRAFAAVPAALLRWGV
MMAR_4333|M.marinum_M LYPQ-LERGERMHRIAADLANARRRMQHPAASASDLAFARVPAALLRWGV
MAV_1257|M.avium_104 LHPR-LGAQARAERIAAGLAAGRRRFGHPATRAADRAFAAVPAALLRWGV
MAB_1278|M.abscessus_ATCC_1997 LCWDEPDLRVRARRIADGIESRRRRAAHPVLVAQRAGGSALPAPMMWAGV
TH_0495|M.thermoresistible__bu -----------------------XXAAHPAMRDAARAAAVVPAPLLRWGV
** . : **.:: *:
Mvan_4596|M.vanbaalenii_PYR-1 GKFNPEARSSTVTGNTVVSSVNRGAKDLSFGDARVVLTTGFPGLSPMMGV
Mflv_2109|M.gilvum_PYR-GCK SHFDPDVRSPTVNGNTVVSSVNRGAADLRFGDARVLLTAGFATLSPMMGV
MSMEG_5205|M.smegmatis_MC2_155 AQFDPTLRSPVATGNTVVSSVNRGAADLRFGSARVAVTAGYPALSPMMGL
Mb1156|M.bovis_AF2122/97 SQFDAEVRPVRVAGNTVVSSVYRGAADLSFGDAPVVLTAGYPALSPAMGL
Rv1125|M.tuberculosis_H37Rv SQFDAEVRPVRVAGNTVVSSVYRGAADLSFGDAPVVLTAGYPALSPAMGL
MMAR_4333|M.marinum_M SQFDADMRPDQVAGNTVVSSVHRGAADLSFGEAPVVLTAGYPALSPVMGL
MAV_1257|M.avium_104 DQFDADQRPDQVAGNTVVSSVNRGPADLSFGGARVVLTAGYPALSPVMGL
MAB_1278|M.abscessus_ATCC_1997 SAFDADLMPPTVAGNTVVSSVVRGAADLVLGGGRVAFTAGFPALSPVMGL
TH_0495|M.thermoresistible__bu AQFDATARSDTVTGNTVVSSVNRGAADLRFGAAPVCLTAGYPGLSPMMGL
*:. . . ******** **. ** :* . * .*:*:. *** **:
Mvan_4596|M.vanbaalenii_PYR-1 THGVHGIGDTVAVSVHAADSAIG---DIDAYLERLERELR-------
Mflv_2109|M.gilvum_PYR-GCK THGVHGIGERVAVSVHAAESAIG---DIDSYLDRLQEALYRPQ----
MSMEG_5205|M.smegmatis_MC2_155 THGVHGIGDTVAVSVHTAASAIGGEDALAAYVERLAKALDG------
Mb1156|M.bovis_AF2122/97 THGVHGIGDTVAISVHAAESAVS---DIDAYMRLLDAALQ-------
Rv1125|M.tuberculosis_H37Rv THGVHGIGDTVAISVHAAESAVS---DIDAYMRLLDAALQ-------
MMAR_4333|M.marinum_M THGVHGIGDTIAVSVHAAQSAVA---DIDSYLELLDQAL--------
MAV_1257|M.avium_104 THGVHGIGDTIAISVHAAASAVP---DVDAYLALLDAAL--------
MAB_1278|M.abscessus_ATCC_1997 THGVHGIGDTVTVSVHTSAAVLP---DADHYEALLAGALDEVSRQLR
TH_0495|M.thermoresistible__bu THGVHGIGDTVAVSVHAAAGSIG---DIDAYLARLDAALP-------
********: :::***:: . : * * *