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MTYSPGNPGYPQAQPAGSYGGVTPSFAHADEGASKLPMYLNIAVAVLGLAAYFASFGPMFTLSTELGGGD GAVSGDTGLPVGVALLAALLAGVALVPKAKSHVTVVAVLGVLGVFLMVSATFNKPSAYSTGWALWVVLAF IVFQAVAAVLALLVETGAITAPAPRPKFDPYGQYGRYGQYGQYGVQPGGYYGQQGAQQAAGLQSPGPQQS PQPPGYGSQYGGYSSSPSQSGSGYTAQPPAQPPAQSGSQQSHQGPSTPPTGFPSFSPPPPVSAGTGSQAG SAPVNYSNPSGGEQSSSPGGAPV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0954 | - | - | 100% (303) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. tuberculosis H37Rv | Rv2507 | - | 1e-06 | 36.36% (88) | proline rich membrane protein |
| M. tuberculosis H37Rv | Rv0020c | TB39.8 | 2e-05 | 32.87% (143) | hypothetical protein Rv0020c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0979 | - | 1e-178 | 100.00% (303) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1872 | - | 1e-46 | 38.82% (322) | hypothetical protein Mflv_1872 |
| M. leprae Br4923 | MLBr_00158 | - | 1e-88 | 54.92% (315) | 34 kDa antigen |
| M. abscessus ATCC 19977 | MAB_1061 | - | 1e-34 | 35.24% (332) | 34 kDa antigenic protein |
| M. marinum M | MMAR_4545 | - | 1e-125 | 71.57% (313) | transmembrane protein |
| M. avium 104 | MAV_1078 | - | 5e-97 | 59.28% (307) | 34 kDa antigenic protein |
| M. smegmatis MC2 155 | MSMEG_5518 | - | 4e-47 | 39.49% (314) | antigen 34 kDa |
| M. thermoresistible (build 8) | TH_2237 | - | 5e-11 | 35.03% (157) | CONSERVED HYPOTHETICAL PROTEIN TB39.8 |
| M. ulcerans Agy99 | MUL_4715 | - | 1e-122 | 71.25% (313) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_4859 | - | 1e-46 | 38.96% (308) | hypothetical protein Mvan_4859 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0954|M.tuberculosis_H37Rv -----------------MTYSPGNPGY----PQAQPAGSYGGVTPSFAHA
Mb0979|M.bovis_AF2122/97 -----------------MTYSPGNPGY----PQAQPAGSYGGVTPSFAHA
MMAR_4545|M.marinum_M -----------------MTYTPGSPGY----PPAQSGGSYGGATPSFAQA
MUL_4715|M.ulcerans_Agy99 -----------------MTYTPGSPGY----PPAQSGGSYGGATPSFAQA
MLBr_00158|M.leprae_Br4923 MHCSSGAVTALEITGGVMTYLPGSPGY----PLVQPAGSYPGATPSFVKS
MAV_1078|M.avium_104 -----------------MTYSPGSPGY----PPAQSGGTYAGATPSFAKD
Mflv_1872|M.gilvum_PYR-GCK -----------------MTYPQGAPGG--FPPAQQPTNQFSAPTQQFSTL
Mvan_4859|M.vanbaalenii_PYR-1 -----------------MSYPQGAPGGQGFPPGQQPTTQFSAPTQQFNRV
MSMEG_5518|M.smegmatis_MC2_155 -----------------MTYPPSSPGY---PPAPQSGSQYGA-TQPFGKP
MAB_1061|M.abscessus_ATCC_1997 -----------------MTYSTGGPGY----QPAQPSNPYGT--PSFVAE
TH_2237|M.thermoresistible__bu -----------------MGLADRIERK----LEATVGDAFARVFGGSIVP
* :
Rv0954|M.tuberculosis_H37Rv D-------EGASKLPMYLNIAVAVLGLAAYFASFGPMFTLST-ELGGGDG
Mb0979|M.bovis_AF2122/97 D-------EGASKLPMYLNIAVAVLGLAAYFASFGPMFTLST-ELGGGDG
MMAR_4545|M.marinum_M D-------DAASKLPMYLNVAVAVLGFLAYLASFGPMFTISS-ELGGGSS
MUL_4715|M.ulcerans_Agy99 D-------DAASKLPMYLNVAVAVLGFLAYLASFGPMFTISS-ELGGGSS
MLBr_00158|M.leprae_Br4923 D-------VGESQLYHYLTIAVVVLGLAVYLGNFGPTFTSSS-DIGPGSG
MAV_1078|M.avium_104 D-------DGKSKLPLYLNIAVVALGFAAYLLNFGPTFTIGA-DLGPGIG
Mflv_1872|M.gilvum_PYR-GCK PPDNEQSQAGANKLPTYLAGATALLGLLTYLASFGPKLSLDD--AQIDVS
Mvan_4859|M.vanbaalenii_PYR-1 P-DADPVAEGPSKLPVYLSAAVVALGLLVYMSSFGPHFTASDFSAFGELT
MSMEG_5518|M.smegmatis_MC2_155 A---ETAPAGESSLPQILLGVAAAAGLIAYFVSYG----IED----AQFA
MAB_1061|M.abscessus_ATCC_1997 P--------NTGALGVYLPGGVLVLSLIGFIAGFGPFYTGKASSGTSGSF
TH_2237|M.thermoresistible__bu Q-------EVEARLRREAQAGARDVGGGRILAPNDYVITLSESDYRKVSA
* . . : .
Rv0954|M.tuberculosis_H37Rv A------VSGDTGLPVGVALLAALLAGVALVPKAKSHVTVVAVLGVLGVF
Mb0979|M.bovis_AF2122/97 A------VSGDTGLPVGVALLAALLAGVALVPKAKSHVTVVAVLGVLGVF
MMAR_4545|M.marinum_M E------ASGDTVLAVGMALLAGLLAGVSLLPKVKSYGAVVAVVSILGVF
MUL_4715|M.ulcerans_Agy99 E------ASGDTVLAVGMALLAGLLAGVSLLPKVKSYGAVVAVVSILGVF
MLBr_00158|M.leprae_Br4923 G------FAGDAGTAVVVALLAALLAGLDLLPKAKSSAGVVGAIAVLGAL
MAV_1078|M.avium_104 G------RAGDAGTAVVVALLAALLAGLGLLPKAKSYVGVVAVVAVLGAL
Mflv_1872|M.gilvum_PYR-GCK L------SPVRLDLALVAAVLAGLIAGVGLLPRQTPRPALVAVLSLLGFL
Mvan_4859|M.vanbaalenii_PYR-1 G------SSFGVILAVISAITAGLFAAVGLLPRQNNFTAVAAVAAVLALL
MSMEG_5518|M.smegmatis_MC2_155 V------GAPIVQVIVVAALAGALLAGVSLLPKQKNHAGVASVLALVAFL
MAB_1061|M.abscessus_ATCC_1997 GGFDLLALSPVFGFAQFALLIAGLTAGVSLLSGKDDKQAPVAILSIVGFL
TH_2237|M.thermoresistible__bu D--------PDRTSTTFAKHLEGYIHDQGWQTYGDVVVRFEQSSNLHTGQ
. . :
Rv0954|M.tuberculosis_H37Rv LMVSATFNKPSAYST-----GWALWVVLAFIVFQAVAAVLALLVETGAIT
Mb0979|M.bovis_AF2122/97 LMVSATFNKPSAYST-----GWALWVVLAFIVFQAVAAVLALLVETGAIT
MMAR_4545|M.marinum_M LMISSTFNKPSAFST-----GWALWIVLVCIVFQAVAAVGALLLETGVVS
MUL_4715|M.ulcerans_Agy99 LMISSTFNKPSAFST-----GWALWIVLVCIVFQAVAAVGALLLETGVVS
MLBr_00158|M.leprae_Br4923 LAISEMINMPAGFSI-----GWAMWFILVCSVLQAIAAVAALLLEAGIIT
MAV_1078|M.avium_104 LAITETINLPAGFAI-----GWAMWPLVACVVLQAIAAVVVVLLDAGVIT
Mflv_1872|M.gilvum_PYR-GCK IALATLFDGFEGTTV-----GWGVYLVIAFTLLQAAVAVVCLLFDSGIIT
Mvan_4859|M.vanbaalenii_PYR-1 LVVAEIINKPAEASI-----GWGLYLVIAFILLQAAVSVVVLLFDAGIIT
MSMEG_5518|M.smegmatis_MC2_155 QSVYLVI--LAGSDS-----GWAFITILVLTLIQAGAALTVLLFDSGILT
MAB_1061|M.abscessus_ATCC_1997 FVLGGLFGNPFAAAVGEVGIGWGLITLAVVSGLQAAVSVYSLLSEVGVIK
TH_2237|M.thermoresistible__bu FRARGLVNPDTTTGEPAQAQQDRAYTAEPGVPPMSDNPSYRGGQGPGRPA
. : . *
Rv0954|M.tuberculosis_H37Rv APAPRPKFDP-YGQYGRYGQYGQYGVQPGGYYGQQGAQ----QAAGLQSP
Mb0979|M.bovis_AF2122/97 APAPRPKFDP-YGQYGRYGQYGQYGVQPGGYYGQQGAQ----QAAGLQSP
MMAR_4545|M.marinum_M APAPRPKFDP-YGQYGQYGQYGQYGGQPGGYYGQPGAQ----QSA----P
MUL_4715|M.ulcerans_Agy99 APAPRPKFDP-YGQYGQYGQY---GGQPGGYYGQPGAQ----QSA----P
MLBr_00158|M.leprae_Br4923 APAPRLSYDP-YLQYGQY------GAQS--YYGQPNRQ----LQVGLNAH
MAV_1078|M.avium_104 APAPRPKYDP-YAQYGQYGQYGQYGQQP--YYGQPGGQP--GGQPGGQQH
Mflv_1872|M.gilvum_PYR-GCK PPVPRPKYDQHQQQYGQYSGG---------YYGQQHGQQHGQQHGGPQQQ
Mvan_4859|M.vanbaalenii_PYR-1 PPVPRPKYEQ-PQSYGQYPG----------YYGQPPTQGGSGQH----QQ
MSMEG_5518|M.smegmatis_MC2_155 PPPPKPAYEQ-QPQYGQYGAPSQ-------YYGQQPGQQPGQQPGQHGQQ
MAB_1061|M.abscessus_ATCC_1997 AKTASPAANPFGNQYQPQQSYYTPAQQQPQQQLPKQGQG---QSYGQAQG
TH_2237|M.thermoresistible__bu DDEYDDRYGRPDDPRGQYPPADQGGYPPRGGYPEQPGGGYPEQQGGYPEQ
Rv0954|M.tuberculosis_H37Rv GPQQSPQ-------PPGYGSQYG-----GYSSSPSQSGSGYTAQPPAQPP
Mb0979|M.bovis_AF2122/97 GPQQSPQ-------PPGYGSQYG-----GYSSSPSQSGSGYTAQPPAQPP
MMAR_4545|M.marinum_M NPQQSPQQ------PSGYGSQYG-----GFTSS---QGSNPSSGGFSAPQ
MUL_4715|M.ulcerans_Agy99 NPQQSPQQ------PSGYGSQYG-----GFTSS---QGSNPSSGGFSAPQ
MLBr_00158|M.leprae_Br4923 SPQQSPA---------GYGAQYG-----AYTS-----SPTQIQAGMPATG
MAV_1078|M.avium_104 GQQHSPQ---------GYGSQYG-----GYGQG---GAPTGGFGAQPSPQ
Mflv_1872|M.gilvum_PYR-GCK GSQQQGLQ-----QRPGYPTPYG-----GYSG------SGQTTGGFPA--
Mvan_4859|M.vanbaalenii_PYR-1 GPQQQ--------QRPGYPTPYG-----GYPG------SGPGTGGFPAG-
MSMEG_5518|M.smegmatis_MC2_155 PGQQQGQPSYQQGQRPGYPSQYG-----GYS-------AGPSTGGFPTPG
MAB_1061|M.abscessus_ATCC_1997 YGQQQGYG-------QQQPAQGY-----GQSGAQAAPGYGQQQSAPAAPP
TH_2237|M.thermoresistible__bu QGGYPDQGGYP--PRGGYPDQGGYPEQGGYPDQGGYPPSYEQRPPAGYGP
.
Rv0954|M.tuberculosis_H37Rv AQSG--SQQSHQGPS--TPPTGFPSFSPPPPVSAGTGSQAGSAPVNYSNP
Mb0979|M.bovis_AF2122/97 AQSG--SQQSHQGPS--TPPTGFPSFSPPPPVSAGTGSQAGSAPVNYSNP
MMAR_4545|M.marinum_M AQSA--PQPMHQTPS--TPPTGFPSFSPPPSVSAGTGSQGGSAPVNYGNP
MUL_4715|M.ulcerans_Agy99 AQSA--PQPMHQTPS--TPPTGFPSFSPPPSVSAGTGSQGGSAPVNYANP
MLBr_00158|M.leprae_Br4923 GFSA--QHSAQQGPS--TPPTGFPSFSPPPSVGAAAGSQAGSAPVSYSNP
MAV_1078|M.avium_104 SGPQ--QSAQQQGPS--TPPTGFPSFSPPPNVG--GGSDSGSATANYSEQ
Mflv_1872|M.gilvum_PYR-GCK ---------AQSGPP--TPPTGFPTYGQPPANN----TPTTQVPTQ--QQ
Mvan_4859|M.vanbaalenii_PYR-1 ---------AQSGPP--TPPTGFPTYGQPPASN----TPTSQAPAP--HQ
MSMEG_5518|M.smegmatis_MC2_155 SQPGGQQHGQQSGPP--TPPTGFPTYGQPQQSSGPSSAPTSQVPAQPQQQ
MAB_1061|M.abscessus_ATCC_1997 SYGGYGQQQPQSAPP--TPPQGFSSSGFTPPSSQPAQQAASSQPTQQYPT
TH_2237|M.thermoresistible__bu PPGGGYDQGYRQPPPGYGPPGGQPGYGAPPAGEYDYGRPPGGRPDDYGRP
:. *. ** * . . . .
Rv0954|M.tuberculosis_H37Rv SG---------GEQSSSPGGAPV---------------------------
Mb0979|M.bovis_AF2122/97 SG---------GEQSSSPGGAPV---------------------------
MMAR_4545|M.marinum_M GGGQQNYGQ--GQQSSSPGSAPV---------------------------
MUL_4715|M.ulcerans_Agy99 SGAQQNYGQ--GQQSSSPGSAPV---------------------------
MLBr_00158|M.leprae_Br4923 TDSKQGFGQGRESTSSSSGSAPV---------------------------
MAV_1078|M.avium_104 AGGQQSYGQ---EPSSPSGPTPA---------------------------
Mflv_1872|M.gilvum_PYR-GCK SPPQS-------GQSSQSGQSSPSGQSSP---------------------
Mvan_4859|M.vanbaalenii_PYR-1 SPS-----------SSQPGQSSS---------------------------
MSMEG_5518|M.smegmatis_MC2_155 QPGQQ-------PSSPQSGQSSS---------------------------
MAB_1061|M.abscessus_ATCC_1997 FGAASGQAAGGEQQSSAGAGGGSASASGDDLFGTSRPSN-----------
TH_2237|M.thermoresistible__bu GHPDQGGYPDQGGGYPDQGYGDQGGGYPDQGYGDQGYGGQPYGRPDYGQQ
. .
Rv0954|M.tuberculosis_H37Rv --------------------------------------------------
Mb0979|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4545|M.marinum_M --------------------------------------------------
MUL_4715|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00158|M.leprae_Br4923 --------------------------------------------------
MAV_1078|M.avium_104 --------------------------------------------------
Mflv_1872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4859|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5518|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1061|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2237|M.thermoresistible__bu PGQGDYGAGGYGDAGGYGAGYGDPGRGDYDYAGAGYGQDAGYGRQDYQQP
Rv0954|M.tuberculosis_H37Rv --------------------------------------------------
Mb0979|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4545|M.marinum_M --------------------------------------------------
MUL_4715|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00158|M.leprae_Br4923 --------------------------------------------------
MAV_1078|M.avium_104 --------------------------------------------------
Mflv_1872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4859|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5518|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1061|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2237|M.thermoresistible__bu PATGRPTTVTLQLDDGSGRTYQLREGANVIGRGQDAQFRLPDTGVSRRHL
Rv0954|M.tuberculosis_H37Rv --------------------------------------------------
Mb0979|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4545|M.marinum_M --------------------------------------------------
MUL_4715|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00158|M.leprae_Br4923 --------------------------------------------------
MAV_1078|M.avium_104 --------------------------------------------------
Mflv_1872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4859|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5518|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1061|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2237|M.thermoresistible__bu EIRWDGQVALLSDLNSTNGTTVNNAPVQEWQLADGDVIRLGHSEIIVRMH