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TYTPGSPGYPPAQSGGSYGGATPSFAQADDAASKLPMYLNVAVAVLGFLAYLASFGPMFTISSELGGGSS EASGDTVLAVGMALLAGLLAGVSLLPKVKSYGAVVAVVSILGVFLMISSTFNKPSAFSTGWALWIVLVCI VFQAVAAVGALLLETGVVSAPAPRPKFDPYGQYGQYGQYGQYGGQPGGYYGQPGAQQSAPNPQQSPQQPS GYGSQYGGFTSSQGSNPSSGGFSAPQAQSAPQPMHQTPSTPPTGFPSFSPPPSVSAGTGSQGGSAPVNYG NPGGGQQNYGQGQQSSSPGSAPV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4545 | - | - | 100% (304) | transmembrane protein |
| M. marinum M | MMAR_0022 | - | 3e-10 | 29.78% (178) | hypothetical protein MMAR_0022 |
| M. marinum M | MMAR_2120 | secD | 2e-08 | 33.04% (112) | protein-export membrane protein SecD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0979 | - | 1e-125 | 71.57% (313) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1872 | - | 8e-48 | 38.92% (316) | hypothetical protein Mflv_1872 |
| M. tuberculosis H37Rv | Rv0954 | - | 1e-125 | 71.57% (313) | transmembrane protein |
| M. leprae Br4923 | MLBr_00158 | - | 8e-91 | 55.63% (311) | 34 kDa antigen |
| M. abscessus ATCC 19977 | MAB_1061 | - | 4e-33 | 35.21% (338) | 34 kDa antigenic protein |
| M. avium 104 | MAV_1078 | - | 1e-101 | 60.71% (308) | 34 kDa antigenic protein |
| M. smegmatis MC2 155 | MSMEG_5518 | - | 3e-45 | 37.38% (321) | antigen 34 kDa |
| M. thermoresistible (build 8) | TH_2237 | - | 7e-10 | 31.01% (158) | CONSERVED HYPOTHETICAL PROTEIN TB39.8 |
| M. ulcerans Agy99 | MUL_4715 | - | 1e-172 | 98.03% (304) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_4859 | - | 1e-49 | 39.27% (303) | hypothetical protein Mvan_4859 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4545|M.marinum_M -----------------MTYTPGSPGY----PPAQSGGSYGGATPSFAQA
MUL_4715|M.ulcerans_Agy99 -----------------MTYTPGSPGY----PPAQSGGSYGGATPSFAQA
Mb0979|M.bovis_AF2122/97 -----------------MTYSPGNPGY----PQAQPAGSYGGVTPSFAHA
Rv0954|M.tuberculosis_H37Rv -----------------MTYSPGNPGY----PQAQPAGSYGGVTPSFAHA
MLBr_00158|M.leprae_Br4923 MHCSSGAVTALEITGGVMTYLPGSPGY----PLVQPAGSYPGATPSFVKS
MAV_1078|M.avium_104 -----------------MTYSPGSPGY----PPAQSGGTYAGATPSFAKD
Mflv_1872|M.gilvum_PYR-GCK -----------------MTYPQGAPGG--FPPAQQPTNQFSAPTQQFSTL
Mvan_4859|M.vanbaalenii_PYR-1 -----------------MSYPQGAPGGQGFPPGQQPTTQFSAPTQQFNRV
MSMEG_5518|M.smegmatis_MC2_155 -----------------MTYPPSSPGY---PPAPQSGSQYGA-TQPFGKP
MAB_1061|M.abscessus_ATCC_1997 -----------------MTYSTGGPGY----QPAQPSNPYGT--PSFVAE
TH_2237|M.thermoresistible__bu -----------------MGLADRIERK----LEATVGDAFARVFGGSIVP
* :
MMAR_4545|M.marinum_M D-------DAASKLPMYLNVAVAVLGFLAYLASFGPMFTISS-ELGGGSS
MUL_4715|M.ulcerans_Agy99 D-------DAASKLPMYLNVAVAVLGFLAYLASFGPMFTISS-ELGGGSS
Mb0979|M.bovis_AF2122/97 D-------EGASKLPMYLNIAVAVLGLAAYFASFGPMFTLST-ELGGGDG
Rv0954|M.tuberculosis_H37Rv D-------EGASKLPMYLNIAVAVLGLAAYFASFGPMFTLST-ELGGGDG
MLBr_00158|M.leprae_Br4923 D-------VGESQLYHYLTIAVVVLGLAVYLGNFGPTFTSSS-DIGPGSG
MAV_1078|M.avium_104 D-------DGKSKLPLYLNIAVVALGFAAYLLNFGPTFTIGA-DLGPGIG
Mflv_1872|M.gilvum_PYR-GCK PPDNEQSQAGANKLPTYLAGATALLGLLTYLASFGPKLSLDD--AQIDVS
Mvan_4859|M.vanbaalenii_PYR-1 P-DADPVAEGPSKLPVYLSAAVVALGLLVYMSSFGPHFTASDFSAFGELT
MSMEG_5518|M.smegmatis_MC2_155 A---ETAPAGESSLPQILLGVAAAAGLIAYFVSYG----IED----AQFA
MAB_1061|M.abscessus_ATCC_1997 P--------NTGALGVYLPGGVLVLSLIGFIAGFGPFYTGKASSGTSGSF
TH_2237|M.thermoresistible__bu Q-------EVEARLRREAQAGARDVGGGRILAPNDYVITLSESDYRKVSA
* . . : .
MMAR_4545|M.marinum_M E------ASGDTVLAVGMALLAGLLAGVSLLPKVKSYGAVVAVVSILGVF
MUL_4715|M.ulcerans_Agy99 E------ASGDTVLAVGMALLAGLLAGVSLLPKVKSYGAVVAVVSILGVF
Mb0979|M.bovis_AF2122/97 A------VSGDTGLPVGVALLAALLAGVALVPKAKSHVTVVAVLGVLGVF
Rv0954|M.tuberculosis_H37Rv A------VSGDTGLPVGVALLAALLAGVALVPKAKSHVTVVAVLGVLGVF
MLBr_00158|M.leprae_Br4923 G------FAGDAGTAVVVALLAALLAGLDLLPKAKSSAGVVGAIAVLGAL
MAV_1078|M.avium_104 G------RAGDAGTAVVVALLAALLAGLGLLPKAKSYVGVVAVVAVLGAL
Mflv_1872|M.gilvum_PYR-GCK L------SPVRLDLALVAAVLAGLIAGVGLLPRQTPRPALVAVLSLLGFL
Mvan_4859|M.vanbaalenii_PYR-1 G------SSFGVILAVISAITAGLFAAVGLLPRQNNFTAVAAVAAVLALL
MSMEG_5518|M.smegmatis_MC2_155 V------GAPIVQVIVVAALAGALLAGVSLLPKQKNHAGVASVLALVAFL
MAB_1061|M.abscessus_ATCC_1997 GGFDLLALSPVFGFAQFALLIAGLTAGVSLLSGKDDKQAPVAILSIVGFL
TH_2237|M.thermoresistible__bu D--------PDRTSTTFAKHLEGYIHDQGWQTYGDVVVRFEQSSNLHTGQ
. . :
MMAR_4545|M.marinum_M LMISSTFNKPSAFST-----GWALWIVLVCIVFQAVAAVGALLLETGVVS
MUL_4715|M.ulcerans_Agy99 LMISSTFNKPSAFST-----GWALWIVLVCIVFQAVAAVGALLLETGVVS
Mb0979|M.bovis_AF2122/97 LMVSATFNKPSAYST-----GWALWVVLAFIVFQAVAAVLALLVETGAIT
Rv0954|M.tuberculosis_H37Rv LMVSATFNKPSAYST-----GWALWVVLAFIVFQAVAAVLALLVETGAIT
MLBr_00158|M.leprae_Br4923 LAISEMINMPAGFSI-----GWAMWFILVCSVLQAIAAVAALLLEAGIIT
MAV_1078|M.avium_104 LAITETINLPAGFAI-----GWAMWPLVACVVLQAIAAVVVVLLDAGVIT
Mflv_1872|M.gilvum_PYR-GCK IALATLFDGFEGTTV-----GWGVYLVIAFTLLQAAVAVVCLLFDSGIIT
Mvan_4859|M.vanbaalenii_PYR-1 LVVAEIINKPAEASI-----GWGLYLVIAFILLQAAVSVVVLLFDAGIIT
MSMEG_5518|M.smegmatis_MC2_155 QSVYLVI--LAGSDS-----GWAFITILVLTLIQAGAALTVLLFDSGILT
MAB_1061|M.abscessus_ATCC_1997 FVLGGLFGNPFAAAVGEVGIGWGLITLAVVSGLQAAVSVYSLLSEVGVIK
TH_2237|M.thermoresistible__bu FRARGLVNPDTTTGEPAQAQQDRAYTAEPGVPPMSDNPSYRGGQGPGRPA
. : . *
MMAR_4545|M.marinum_M APAPRPKFDP-YGQYGQYGQYGQYGGQPGGYYGQPGAQ----QSA----P
MUL_4715|M.ulcerans_Agy99 APAPRPKFDP-YGQYGQYGQY---GGQPGGYYGQPGAQ----QSA----P
Mb0979|M.bovis_AF2122/97 APAPRPKFDP-YGQYGRYGQYGQYGVQPGGYYGQQGAQ----QAAGLQSP
Rv0954|M.tuberculosis_H37Rv APAPRPKFDP-YGQYGRYGQYGQYGVQPGGYYGQQGAQ----QAAGLQSP
MLBr_00158|M.leprae_Br4923 APAPRLSYDP-YLQYGQY------GAQS--YYGQPNRQ----LQVGLNAH
MAV_1078|M.avium_104 APAPRPKYDP-YAQYGQYGQYGQYGQQP--YYGQPGGQP--GGQPGGQQH
Mflv_1872|M.gilvum_PYR-GCK PPVPRPKYDQHQQQYGQYSGG---------YYGQQHGQQHGQQHGGPQQQ
Mvan_4859|M.vanbaalenii_PYR-1 PPVPRPKYEQ-PQSYGQYPG----------YYGQPPTQGGSGQH----QQ
MSMEG_5518|M.smegmatis_MC2_155 PPPPKPAYEQ-QPQYGQYGAPSQ-------YYGQQPGQQPGQQPGQHGQQ
MAB_1061|M.abscessus_ATCC_1997 AKTASPAANPFGNQYQPQQSYYTPAQQQPQQQLPKQGQG---QSYGQAQG
TH_2237|M.thermoresistible__bu DDEYDDRYGRPDDPRGQYPPADQGGYPPRGGYPEQPGGGYPEQQGGYPEQ
MMAR_4545|M.marinum_M NPQQSPQQ------PSGYGSQYG-----GFTSS---QGSNPSSGGFSAPQ
MUL_4715|M.ulcerans_Agy99 NPQQSPQQ------PSGYGSQYG-----GFTSS---QGSNPSSGGFSAPQ
Mb0979|M.bovis_AF2122/97 GPQQSPQ-------PPGYGSQYG-----GYSSSPSQSGSGYTAQPPAQPP
Rv0954|M.tuberculosis_H37Rv GPQQSPQ-------PPGYGSQYG-----GYSSSPSQSGSGYTAQPPAQPP
MLBr_00158|M.leprae_Br4923 SPQQSPA---------GYGAQYG-----AYTS-----SPTQIQAGMPATG
MAV_1078|M.avium_104 GQQHSPQ---------GYGSQYG-----GYGQG---GAPTGGFGAQPSPQ
Mflv_1872|M.gilvum_PYR-GCK GSQQQGLQ-----QRPGYPTPYG-----GYSG------SGQTTGGFPA--
Mvan_4859|M.vanbaalenii_PYR-1 GPQQQ--------QRPGYPTPYG-----GYPG------SGPGTGGFPAG-
MSMEG_5518|M.smegmatis_MC2_155 PGQQQGQPSYQQGQRPGYPSQYG-----GYS-------AGPSTGGFPTPG
MAB_1061|M.abscessus_ATCC_1997 YGQQQGYG-------QQQPAQGY-----GQSGAQAAPGYGQQQSAPAAPP
TH_2237|M.thermoresistible__bu QGGYPDQGGYP--PRGGYPDQGGYPEQGGYPDQGGYPPSYEQRPPAGYGP
.
MMAR_4545|M.marinum_M AQSA--PQPMHQTPS--TPPTGFPSFSPPPSVSAGTGSQGGSAPVNYGNP
MUL_4715|M.ulcerans_Agy99 AQSA--PQPMHQTPS--TPPTGFPSFSPPPSVSAGTGSQGGSAPVNYANP
Mb0979|M.bovis_AF2122/97 AQSG--SQQSHQGPS--TPPTGFPSFSPPPPVSAGTGSQAGSAPVNYSNP
Rv0954|M.tuberculosis_H37Rv AQSG--SQQSHQGPS--TPPTGFPSFSPPPPVSAGTGSQAGSAPVNYSNP
MLBr_00158|M.leprae_Br4923 GFSA--QHSAQQGPS--TPPTGFPSFSPPPSVGAAAGSQAGSAPVSYSNP
MAV_1078|M.avium_104 SGPQ--QSAQQQGPS--TPPTGFPSFSPPPNVG--GGSDSGSATANYSEQ
Mflv_1872|M.gilvum_PYR-GCK ---------AQSGPP--TPPTGFPTYGQPPANN----TPTTQVPTQ--QQ
Mvan_4859|M.vanbaalenii_PYR-1 ---------AQSGPP--TPPTGFPTYGQPPASN----TPTSQAPAP--HQ
MSMEG_5518|M.smegmatis_MC2_155 SQPGGQQHGQQSGPP--TPPTGFPTYGQPQQSSGPSSAPTSQVPAQPQQQ
MAB_1061|M.abscessus_ATCC_1997 SYGGYGQQQPQSAPP--TPPQGFSSSGFTPPSSQPAQQAASSQPTQQYPT
TH_2237|M.thermoresistible__bu PPGGGYDQGYRQPPPGYGPPGGQPGYGAPPAGEYDYGRPPGGRPDDYGRP
:. *. ** * . . . .
MMAR_4545|M.marinum_M GGGQQNYGQ--GQQSSSPGSAPV---------------------------
MUL_4715|M.ulcerans_Agy99 SGAQQNYGQ--GQQSSSPGSAPV---------------------------
Mb0979|M.bovis_AF2122/97 SG---------GEQSSSPGGAPV---------------------------
Rv0954|M.tuberculosis_H37Rv SG---------GEQSSSPGGAPV---------------------------
MLBr_00158|M.leprae_Br4923 TDSKQGFGQGRESTSSSSGSAPV---------------------------
MAV_1078|M.avium_104 AGGQQSYGQ---EPSSPSGPTPA---------------------------
Mflv_1872|M.gilvum_PYR-GCK SPPQS-------GQSSQSGQSSPSGQSSP---------------------
Mvan_4859|M.vanbaalenii_PYR-1 SPS-----------SSQPGQSSS---------------------------
MSMEG_5518|M.smegmatis_MC2_155 QPGQQ-------PSSPQSGQSSS---------------------------
MAB_1061|M.abscessus_ATCC_1997 FGAASGQAAGGEQQSSAGAGGGSASASGDDLFGTSRPSN-----------
TH_2237|M.thermoresistible__bu GHPDQGGYPDQGGGYPDQGYGDQGGGYPDQGYGDQGYGGQPYGRPDYGQQ
. .
MMAR_4545|M.marinum_M --------------------------------------------------
MUL_4715|M.ulcerans_Agy99 --------------------------------------------------
Mb0979|M.bovis_AF2122/97 --------------------------------------------------
Rv0954|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00158|M.leprae_Br4923 --------------------------------------------------
MAV_1078|M.avium_104 --------------------------------------------------
Mflv_1872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4859|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5518|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1061|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2237|M.thermoresistible__bu PGQGDYGAGGYGDAGGYGAGYGDPGRGDYDYAGAGYGQDAGYGRQDYQQP
MMAR_4545|M.marinum_M --------------------------------------------------
MUL_4715|M.ulcerans_Agy99 --------------------------------------------------
Mb0979|M.bovis_AF2122/97 --------------------------------------------------
Rv0954|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00158|M.leprae_Br4923 --------------------------------------------------
MAV_1078|M.avium_104 --------------------------------------------------
Mflv_1872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4859|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5518|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1061|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2237|M.thermoresistible__bu PATGRPTTVTLQLDDGSGRTYQLREGANVIGRGQDAQFRLPDTGVSRRHL
MMAR_4545|M.marinum_M --------------------------------------------------
MUL_4715|M.ulcerans_Agy99 --------------------------------------------------
Mb0979|M.bovis_AF2122/97 --------------------------------------------------
Rv0954|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00158|M.leprae_Br4923 --------------------------------------------------
MAV_1078|M.avium_104 --------------------------------------------------
Mflv_1872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4859|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5518|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1061|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2237|M.thermoresistible__bu EIRWDGQVALLSDLNSTNGTTVNNAPVQEWQLADGDVIRLGHSEIIVRMH