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M. leprae Br4923 MLBr_00158 (-)

annotation: 34 kDa antigen
coordinates: 221684 - 222628
length: 314

LHCSSGAVTALEITGGVMTYLPGSPGYPLVQPAGSYPGATPSFVKSDVGESQLYHYLTIAVVVLGLAVYL
GNFGPTFTSSSDIGPGSGGFAGDAGTAVVVALLAALLAGLDLLPKAKSSAGVVGAIAVLGALLAISEMIN
MPAGFSIGWAMWFILVCSVLQAIAAVAALLLEAGIITAPAPRLSYDPYLQYGQYGAQSYYGQPNRQLQVG
LNAHSPQQSPAGYGAQYGAYTSSPTQIQAGMPATGGFSAQHSAQQGPSTPPTGFPSFSPPPSVGAAAGSQ
AGSAPVSYSNPTDSKQGFGQGRESTSSSSGSAPV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00158--100% (314)34 kDa antigen

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0979-3e-8854.92% (315) transmembrane protein
M. gilvum PYR-GCKMflv_1872-3e-3935.26% (312) hypothetical protein Mflv_1872
M. tuberculosis H37RvRv0954-3e-8854.92% (315) transmembrane protein
M. abscessus ATCC 19977MAB_1061-7e-2732.13% (333) 34 kDa antigenic protein
M. marinum MMMAR_4545-3e-9055.63% (311) transmembrane protein
M. avium 104MAV_1078-6e-9862.30% (313) 34 kDa antigenic protein
M. smegmatis MC2 155MSMEG_5518-3e-4037.38% (313) antigen 34 kDa
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_4715-2e-9156.17% (308) transmembrane protein
M. vanbaalenii PYR-1Mvan_4859-9e-4639.93% (293) hypothetical protein Mvan_4859

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_00158|M.leprae_Br4923          MHCSSGAVTALEITGGVMTYLPGSPGY----PLVQPAGSYPGATPSFVKS
MAV_1078|M.avium_104                -----------------MTYSPGSPGY----PPAQSGGTYAGATPSFAKD
Mb0979|M.bovis_AF2122/97            -----------------MTYSPGNPGY----PQAQPAGSYGGVTPSFAHA
Rv0954|M.tuberculosis_H37Rv         -----------------MTYSPGNPGY----PQAQPAGSYGGVTPSFAHA
MMAR_4545|M.marinum_M               -----------------MTYTPGSPGY----PPAQSGGSYGGATPSFAQA
MUL_4715|M.ulcerans_Agy99           -----------------MTYTPGSPGY----PPAQSGGSYGGATPSFAQA
Mflv_1872|M.gilvum_PYR-GCK          -----------------MTYPQGAPGG--FPPAQQPTNQFSAPTQQFSTL
Mvan_4859|M.vanbaalenii_PYR-1       -----------------MSYPQGAPGGQGFPPGQQPTTQFSAPTQQFNRV
MSMEG_5518|M.smegmatis_MC2_155      -----------------MTYPPSSPGY---PPAPQSGSQYGA-TQPFGKP
MAB_1061|M.abscessus_ATCC_1997      -----------------MTYSTGGPGY----QPAQPSNPYGT--PSFVAE
                                                     *:*  . **        *.   :      *   

MLBr_00158|M.leprae_Br4923          D-------VGESQLYHYLTIAVVVLGLAVYLGNFGPTFTSSS-DIGPGSG
MAV_1078|M.avium_104                D-------DGKSKLPLYLNIAVVALGFAAYLLNFGPTFTIGA-DLGPGIG
Mb0979|M.bovis_AF2122/97            D-------EGASKLPMYLNIAVAVLGLAAYFASFGPMFTLST-ELGGGDG
Rv0954|M.tuberculosis_H37Rv         D-------EGASKLPMYLNIAVAVLGLAAYFASFGPMFTLST-ELGGGDG
MMAR_4545|M.marinum_M               D-------DAASKLPMYLNVAVAVLGFLAYLASFGPMFTISS-ELGGGSS
MUL_4715|M.ulcerans_Agy99           D-------DAASKLPMYLNVAVAVLGFLAYLASFGPMFTISS-ELGGGSS
Mflv_1872|M.gilvum_PYR-GCK          PPDNEQSQAGANKLPTYLAGATALLGLLTYLASFGPKLSLDD--AQIDVS
Mvan_4859|M.vanbaalenii_PYR-1       P-DADPVAEGPSKLPVYLSAAVVALGLLVYMSSFGPHFTASDFSAFGELT
MSMEG_5518|M.smegmatis_MC2_155      A---ETAPAGESSLPQILLGVAAAAGLIAYFVSYG----IED----AQFA
MAB_1061|M.abscessus_ATCC_1997      P--------NTGALGVYLPGGVLVLSLIGFIAGFGPFYTGKASSGTSGSF
                                               . *   *   .   .:  :: .:*               

MLBr_00158|M.leprae_Br4923          G------FAGDAGTAVVVALLAALLAGLDLLPKAKSSAGVVGAIAVLGAL
MAV_1078|M.avium_104                G------RAGDAGTAVVVALLAALLAGLGLLPKAKSYVGVVAVVAVLGAL
Mb0979|M.bovis_AF2122/97            A------VSGDTGLPVGVALLAALLAGVALVPKAKSHVTVVAVLGVLGVF
Rv0954|M.tuberculosis_H37Rv         A------VSGDTGLPVGVALLAALLAGVALVPKAKSHVTVVAVLGVLGVF
MMAR_4545|M.marinum_M               E------ASGDTVLAVGMALLAGLLAGVSLLPKVKSYGAVVAVVSILGVF
MUL_4715|M.ulcerans_Agy99           E------ASGDTVLAVGMALLAGLLAGVSLLPKVKSYGAVVAVVSILGVF
Mflv_1872|M.gilvum_PYR-GCK          L------SPVRLDLALVAAVLAGLIAGVGLLPRQTPRPALVAVLSLLGFL
Mvan_4859|M.vanbaalenii_PYR-1       G------SSFGVILAVISAITAGLFAAVGLLPRQNNFTAVAAVAAVLALL
MSMEG_5518|M.smegmatis_MC2_155      V------GAPIVQVIVVAALAGALLAGVSLLPKQKNHAGVASVLALVAFL
MAB_1061|M.abscessus_ATCC_1997      GGFDLLALSPVFGFAQFALLIAGLTAGVSLLSGKDDKQAPVAILSIVGFL
                                            .          : ..* *.: *:.        ..  .::. :

MLBr_00158|M.leprae_Br4923          LAISEMINMPAGFSI-----GWAMWFILVCSVLQAIAAVAALLLEAGIIT
MAV_1078|M.avium_104                LAITETINLPAGFAI-----GWAMWPLVACVVLQAIAAVVVVLLDAGVIT
Mb0979|M.bovis_AF2122/97            LMVSATFNKPSAYST-----GWALWVVLAFIVFQAVAAVLALLVETGAIT
Rv0954|M.tuberculosis_H37Rv         LMVSATFNKPSAYST-----GWALWVVLAFIVFQAVAAVLALLVETGAIT
MMAR_4545|M.marinum_M               LMISSTFNKPSAFST-----GWALWIVLVCIVFQAVAAVGALLLETGVVS
MUL_4715|M.ulcerans_Agy99           LMISSTFNKPSAFST-----GWALWIVLVCIVFQAVAAVGALLLETGVVS
Mflv_1872|M.gilvum_PYR-GCK          IALATLFDGFEGTTV-----GWGVYLVIAFTLLQAAVAVVCLLFDSGIIT
Mvan_4859|M.vanbaalenii_PYR-1       LVVAEIINKPAEASI-----GWGLYLVIAFILLQAAVSVVVLLFDAGIIT
MSMEG_5518|M.smegmatis_MC2_155      QSVYLVI--LAGSDS-----GWAFITILVLTLIQAGAALTVLLFDSGILT
MAB_1061|M.abscessus_ATCC_1997      FVLGGLFGNPFAAAVGEVGIGWGLITLAVVSGLQAAVSVYSLLSEVGVIK
                                      :   :             **..  : .   :** .::  :* : * :.

MLBr_00158|M.leprae_Br4923          APAPRLSYDP-YLQYGQY------GAQS--YYGQPNRQ----LQVGLNAH
MAV_1078|M.avium_104                APAPRPKYDP-YAQYGQYGQYGQYGQQP--YYGQPGGQP--GGQPGGQQH
Mb0979|M.bovis_AF2122/97            APAPRPKFDP-YGQYGRYGQYGQYGVQPGGYYGQQGAQ----QAAGLQSP
Rv0954|M.tuberculosis_H37Rv         APAPRPKFDP-YGQYGRYGQYGQYGVQPGGYYGQQGAQ----QAAGLQSP
MMAR_4545|M.marinum_M               APAPRPKFDP-YGQYGQYGQYGQYGGQPGGYYGQPGAQ----QSA----P
MUL_4715|M.ulcerans_Agy99           APAPRPKFDP-YGQYGQYGQY---GGQPGGYYGQPGAQ----QSA----P
Mflv_1872|M.gilvum_PYR-GCK          PPVPRPKYDQHQQQYGQYSGG---------YYGQQHGQQHGQQHGGPQQQ
Mvan_4859|M.vanbaalenii_PYR-1       PPVPRPKYEQ-PQSYGQYPG----------YYGQPPTQGGSGQH----QQ
MSMEG_5518|M.smegmatis_MC2_155      PPPPKPAYEQ-QPQYGQYGAPSQ-------YYGQQPGQQPGQQPGQHGQQ
MAB_1061|M.abscessus_ATCC_1997      AKTASPAANPFGNQYQPQQS----------YYTPAQQQPQQQLPKQGQGQ
                                    .  .    :    .*               **     *            

MLBr_00158|M.leprae_Br4923          SPQQSPA---------GYGAQYGAYTS-----SPTQIQAGMPATGGFSA-
MAV_1078|M.avium_104                GQQHSPQ---------GYGSQYGGYGQG---GAPTGGFGAQPSPQSGPQ-
Mb0979|M.bovis_AF2122/97            GPQQSPQ-------PPGYGSQYGGYSSSPSQSGSGYTAQPPAQPPAQSG-
Rv0954|M.tuberculosis_H37Rv         GPQQSPQ-------PPGYGSQYGGYSSSPSQSGSGYTAQPPAQPPAQSG-
MMAR_4545|M.marinum_M               NPQQSPQQ------PSGYGSQYGGFTSS---QGSNPSSGGFSAPQAQSA-
MUL_4715|M.ulcerans_Agy99           NPQQSPQQ------PSGYGSQYGGFTSS---QGSNPSSGGFSAPQAQSA-
Mflv_1872|M.gilvum_PYR-GCK          GSQQQGLQ-----QRPGYPTPYGGYSG------SGQTTGGFPA-------
Mvan_4859|M.vanbaalenii_PYR-1       GPQQQ--------QRPGYPTPYGGYPG------SGPGTGGFPAG------
MSMEG_5518|M.smegmatis_MC2_155      PGQQQGQPSYQQGQRPGYPSQYGGYS-------AGPSTGGFPTPGSQPGG
MAB_1061|M.abscessus_ATCC_1997      SYGQAQGYGQQQGYGQQQPAQGYGQSGAQAAPGYGQQQSAPAAPPSYGGY
                                       :               :   .                 .        

MLBr_00158|M.leprae_Br4923          -QHSAQQGPSTPPTGFPSFSPPPSVGAAAGSQAGSAPVSYSNPTDSKQGF
MAV_1078|M.avium_104                -QSAQQQGPSTPPTGFPSFSPPPNVG--GGSDSGSATANYSEQAGGQQSY
Mb0979|M.bovis_AF2122/97            -SQQSHQGPSTPPTGFPSFSPPPPVSAGTGSQAGSAPVNYSNPSG-----
Rv0954|M.tuberculosis_H37Rv         -SQQSHQGPSTPPTGFPSFSPPPPVSAGTGSQAGSAPVNYSNPSG-----
MMAR_4545|M.marinum_M               -PQPMHQTPSTPPTGFPSFSPPPSVSAGTGSQGGSAPVNYGNPGGGQQNY
MUL_4715|M.ulcerans_Agy99           -PQPMHQTPSTPPTGFPSFSPPPSVSAGTGSQGGSAPVNYANPSGAQQNY
Mflv_1872|M.gilvum_PYR-GCK          ----AQSGPPTPPTGFPTYGQPPANN----TPTTQVPTQ--QQSPPQS--
Mvan_4859|M.vanbaalenii_PYR-1       ----AQSGPPTPPTGFPTYGQPPASN----TPTSQAPAP--HQSPS----
MSMEG_5518|M.smegmatis_MC2_155      QQHGQQSGPPTPPTGFPTYGQPQQSSGPSSAPTSQVPAQPQQQQPGQQ--
MAB_1061|M.abscessus_ATCC_1997      GQQQPQSAPPTPPQGFSSSGFTPPSSQPAQQAASSQPTQQYPTFGAASGQ
                                         :. *.*** **.: . .   .        . ..            

MLBr_00158|M.leprae_Br4923          GQGRESTSSSSGSAPV----------------
MAV_1078|M.avium_104                GQ---EPSSPSGPTPA----------------
Mb0979|M.bovis_AF2122/97            ----GEQSSSPGGAPV----------------
Rv0954|M.tuberculosis_H37Rv         ----GEQSSSPGGAPV----------------
MMAR_4545|M.marinum_M               GQ--GQQSSSPGSAPV----------------
MUL_4715|M.ulcerans_Agy99           GQ--GQQSSSPGSAPV----------------
Mflv_1872|M.gilvum_PYR-GCK          -----GQSSQSGQSSPSGQSSP----------
Mvan_4859|M.vanbaalenii_PYR-1       -------SSQPGQSSS----------------
MSMEG_5518|M.smegmatis_MC2_155      -----PSSPQSGQSSS----------------
MAB_1061|M.abscessus_ATCC_1997      AAGGEQQSSAGAGGGSASASGDDLFGTSRPSN
                                           *.  .