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GSQKRLVQRVERKLEQTVGDAFARIFGGSIVPQEVEALLRREAADGIQSLQGNRLLAPNEYIITLGVHDF EKLGADPELKSTGFARDLADYIQEQGWQTYGDVVVRFEQSSNLHTGQFRARGTVNPDVETHPPVIDCARP QSNHAFGAEPGVAPMSDNSSYRGGQGQGRPDEYYDDRYARPQEDPRGGPDPQGGSDPRGGYPPETGGYPP QPGYPRPRHPDQGDYPEQIGYPDQGGYPEQRGYPEQRGYPDQRGYQDQGRGYPDQGQGGYPPPYEQRPPV SPGPAAGYGAPGYDQGYRQSGGYGPSPGGGQPGYGGYGEYGRGPARHEEGSYVPSGPPGPPEQRPAYPDQ GGYDQGYQQGATTYGRQDYGGGADYTRYTESPRVPGYAPQGGGYAEPAGRDYDYGQSGAPDYGQPAPGGY SGYGQGGYGSAGTSVTLQLDDGSGRTYQLREGSNIIGRGQDAQFRLPDTGVSRRHLEIRWDGQVALLADL NSTNGTTVNNAPVQEWQLADGDVIRLGHSEIIVRMH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0020c | TB39.8 | - | 100% (527) | hypothetical protein Rv0020c |
| M. tuberculosis H37Rv | Rv3507 | PE_PGRS53 | 2e-09 | 27.82% (284) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 7e-09 | 27.50% (320) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0020c | TB39.8 | 0.0 | 97.91% (527) | hypothetical protein Mb0020c |
| M. gilvum PYR-GCK | Mflv_0806 | - | 1e-162 | 61.54% (533) | FHA domain-containing protein |
| M. leprae Br4923 | MLBr_00022 | - | 0.0 | 71.75% (531) | hypothetical protein MLBr_00022 |
| M. abscessus ATCC 19977 | MAB_0039c | - | 1e-127 | 53.58% (530) | hypothetical protein MAB_0039c |
| M. marinum M | MMAR_0022 | - | 0.0 | 77.48% (555) | hypothetical protein MMAR_0022 |
| M. avium 104 | MAV_0024 | - | 0.0 | 70.61% (558) | xyppx repeat-containing protein |
| M. smegmatis MC2 155 | MSMEG_0035 | - | 1e-167 | 60.37% (545) | FHA domain-containing protein |
| M. thermoresistible (build 8) | TH_2237 | - | 1e-172 | 62.34% (547) | CONSERVED HYPOTHETICAL PROTEIN TB39.8 |
| M. ulcerans Agy99 | MUL_0024 | - | 0.0 | 79.48% (541) | hypothetical protein MUL_0024 |
| M. vanbaalenii PYR-1 | Mvan_0029 | - | 1e-168 | 61.70% (530) | FHA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0806|M.gilvum_PYR-GCK ------MGLVDRFERKLEDSVGDAFARVFGGSIVPREVEVLLRREAETGA
Mvan_0029|M.vanbaalenii_PYR-1 ------MGLVGRFERKLEDKVGDAFARVFGGSIVPQEVESLLRREADAGV
TH_2237|M.thermoresistible__bu ------MGLADRIERKLEATVGDAFARVFGGSIVPQEVEARLRREAQAGA
MSMEG_0035|M.smegmatis_MC2_155 MKAGDVMGLVDRIERKLESTVGDAFARVFGGSIVPQEVEVALRREAETRA
Rv0020c|M.tuberculosis_H37Rv --MGSQKRLVQRVERKLEQTVGDAFARIFGGSIVPQEVEALLRREAADGI
Mb0020c|M.bovis_AF2122/97 --MGSQKRLVQRVERKLEQTVGDAFARIFGGSIVPQEVEALLRREAADRI
MMAR_0022|M.marinum_M --MGSQKGLVQRIERKLESTVGDAFARMFGGSIVPQEVEALLRREAADGV
MUL_0024|M.ulcerans_Agy99 --MGSQKGLVQRIERKLESTVGDAFARMFGGSIVPQEVEALLRREAADGV
MLBr_00022|M.leprae_Br4923 --MDNQKELIQRIERKLESSIDDAFARMFGGSIVPQEVEALLRREASDGV
MAV_0024|M.avium_104 --MSSQRGLVARIERKLEATVDNAFARVFGGPIVPQEVEALLCREARDGV
MAB_0039c|M.abscessus_ATCC_199 ------MGIVQRFERKLEDVVGDAFARVFGGSIVPQEVQASLRREAADGV
: *.***** :.:****:***.***:**: * ***
Mflv_0806|M.gilvum_PYR-GCK RKVPGGHILAPNDYVITLSVPDFQKVNADPDITATTFAKHLEGYIHEQGW
Mvan_0029|M.vanbaalenii_PYR-1 RELHGGRILAPNDYVITLSVPDYRKVSADPDITATTFAKHLEGYIHEQGW
TH_2237|M.thermoresistible__bu RDVGGGRILAPNDYVITLSESDYRKVSADPDRTSTTFAKHLEGYIHDQGW
MSMEG_0035|M.smegmatis_MC2_155 RTVAGGQVLAPNDYVITLSGTDYQKVRADTDLTSTTFAKHLKGYIHDQGW
Rv0020c|M.tuberculosis_H37Rv QSLQGNRLLAPNEYIITLGVHDFEKLGADPELKSTGFARDLADYIQEQGW
Mb0020c|M.bovis_AF2122/97 QSLQGNRLLAPNEYIITLGVHDFEKLGADPELKSTGFARDLADYIQEQGW
MMAR_0022|M.marinum_M RSLPGNRLLAPNEYIITLSVHDAEELGADPHLTSSEFARYLADYIHEQGW
MUL_0024|M.ulcerans_Agy99 RSLPGNRLLAPNEYIITLSVHDAEELGADPHLTSSEFARYLADYIHEQGW
MLBr_00022|M.leprae_Br4923 RSLQGNRLLAPNEYIITLGVHDLEKMKADPDLTSSAFASDLADYIHEQGW
MAV_0024|M.avium_104 QKLHGNRLLAPNEYIITLGMHDFEKVSADPDLTSSAFARYLADYIHEQGW
MAB_0039c|M.abscessus_ATCC_199 RSAGQGRLLAPNEFFVLLSTADHEKAADDRDLNPDTFAELLREYIRDQGW
: .::****::.: *. * .: * . .. ** * **::***
Mflv_0806|M.gilvum_PYR-GCK QTYGDVVVRFEQSPNLHTGQFRARGAVNPDA----TTVEPAPPSRDATSQ
Mvan_0029|M.vanbaalenii_PYR-1 QTYGDVVVRFEQSPNLHTGQFRARAAVNPDA----TTVEPAPPPRDVTSQ
TH_2237|M.thermoresistible__bu QTYGDVVVRFEQSSNLHTGQFRARGLVNPDT----TTGEPAQAQQDRAYT
MSMEG_0035|M.smegmatis_MC2_155 QTYGEVVVRFEQSPNLHTGQFRARGAVNPDS----TAGESARAPRDHAFT
Rv0020c|M.tuberculosis_H37Rv QTYGDVVVRFEQSSNLHTGQFRARGTVNPDVETHPPVIDCARPQSNHAFG
Mb0020c|M.bovis_AF2122/97 QTYGDVVVRFEQSSNLHTGQFRARGTVNPDVETHPPVIDCARPQSNHAFG
MMAR_0022|M.marinum_M QTYGDVVVRFEQSSSLHTGQFRARGAVNPDVEPRPTVNDSAQPQSNDAFG
MUL_0024|M.ulcerans_Agy99 QTYADVVVRFEQSSSLHTGQFRARGAVNPDVEPRPTVNDSAQPQSNDAFG
MLBr_00022|M.leprae_Br4923 QTYGDVVVRFDQSSSLHTGQIRARSVVNPDVEPRPTVNDPVRTQSNQAFS
MAV_0024|M.avium_104 QTYGEVVVRFEQSSSLRTGQYRACGAVNPDVQPRPTVDDPVRPQSNNAFG
MAB_0039c|M.abscessus_ATCC_199 QTYGEVVVRFEQSPNLHTGQFRTRGVVNPDS--KRDRPHGAVTTAPPTPD
***.:*****:**..*:*** *: . **** . . . :
Mflv_0806|M.gilvum_PYR-GCK AEPGVPAMTDNPSYRGGPGQGRP-DEY--YN----RPPENRPEDEGGYNR
Mvan_0029|M.vanbaalenii_PYR-1 AEPGVPPMTDNPTYRGGQGPGRPADDY--YN----RPEDERP--------
TH_2237|M.thermoresistible__bu AEPGVPPMSDNPSYRGGQGPGRPADDE--YDDRYGRPDDPRGQ----YPP
MSMEG_0035|M.smegmatis_MC2_155 AESGEPPMTDNPNYRGGQGPARPGDEY--YDERYGRQDDPRG--------
Rv0020c|M.tuberculosis_H37Rv AEPGVAPMSDNSSYRGGQGQGRPDE-Y--YDDRYARPQEDPRGGPD----
Mb0020c|M.bovis_AF2122/97 AEPGVAPMSDNSSYRGGQGQGRPDE-Y--YDDRYARPQEDPRGGPD----
MMAR_0022|M.marinum_M AEPGVPPMTDNSSYRGGQGQGRPDE-Y--YDERYARPQEDPRGGP-----
MUL_0024|M.ulcerans_Agy99 AEPGVPPMTDNSSYRGGQGQGRPDE-Y--YDERYARPQEDPRGGP-----
MLBr_00022|M.leprae_Br4923 AEPGVPPMTDNSSYRGGQGQGRPS------DDYYGRPQDDPRGAD-----
MAV_0024|M.avium_104 EERGVAPMTDNSSYRGAQGPGRPGDEY--YDERYGRPQDDARGGSE----
MAB_0039c|M.abscessus_ATCC_199 PQPG-APMTDNP----GPQQGRPGEEYGREDDRYGRPDQDPRG-------
: * ..*:**. . .** : * :
Mflv_0806|M.gilvum_PYR-GCK PENRGDEQRGGYPHGDQGGYP--AQDQGYP-----PRGGYPEQG------
Mvan_0029|M.vanbaalenii_PYR-1 --NRGDEPRGGYPPADQGGYPPPADQGGYP-----PRGGYPEHGGYPEHG
TH_2237|M.thermoresistible__bu ADQGGYPPRGGYPEQPGGGYP--EQQGGYPE----QQGGYPDQGGYPPRG
MSMEG_0035|M.smegmatis_MC2_155 --GQYPPEQGGYPPQDQGGYP--PRGGGYP-----DQGGYPDQG------
Rv0020c|M.tuberculosis_H37Rv -PQGGSDPRGGYPP-ETGGYP---PQPGYPRPRHPDQGDYPEQIGYPDQG
Mb0020c|M.bovis_AF2122/97 -PQGGSDPRGGYPP-ETGGYP---PQPGYPRPRHPGQGDYPEQIGYPDQG
MMAR_0022|M.marinum_M --HGGPDPRGGYPP-EAGGYP---PQPGYPPPRPQDQGGYPEQGGYPEQG
MUL_0024|M.ulcerans_Agy99 --HGGPDPRGGYPP-EAGGYP---PQPGYPPPRPQDQGGYPEQGGYPDQR
MLBr_00022|M.leprae_Br4923 -PQGGQDPRGCYPP-KPGSYP---QQAGHPPLHRPDQGGYPGQG------
MAV_0024|M.avium_104 -PQGAPDQRGGYPP-EQGGYP---PQQGYPPPRHPEQGGYPEQGGYPPPQ
MAB_0039c|M.abscessus_ATCC_199 ---QQPQGGQGYPP-RQGGYE----GGGYG------QGQPYGQDY-----
** *.* *: :* :
Mflv_0806|M.gilvum_PYR-GCK -------------GYQD--QGGYQGQG-GYP-------------PQSYEQ
Mvan_0029|M.vanbaalenii_PYR-1 -------------GYPD--QGGYPEQG-GYP-------------PQSYEQ
TH_2237|M.thermoresistible__bu -------------GYPD--QGGYPEQG-GYPDQG--------GYPPSYEQ
MSMEG_0035|M.smegmatis_MC2_155 -------------GYPD--QGGYPDQG-GYP-------------PQSYEQ
Rv0020c|M.tuberculosis_H37Rv GYPEQRGYPEQR-GYPD--QRGYQDQGRGYPDQG------QGGYPPPYEQ
Mb0020c|M.bovis_AF2122/97 GYPE------QR-GYPD--QRGHQDQGRGYPDQG------QGGYPPPYEQ
MMAR_0022|M.marinum_M GYPDQRGYQDQR-GYQD--QRGYPDQG-GYPDQRGYPE--QGGYPPSYEQ
MUL_0024|M.ulcerans_Agy99 GYPDQRGYQDQR-GYPD--QRDYQDQG-GYPDQRGYPE--QGGYPPSYEQ
MLBr_00022|M.leprae_Br4923 -------------GYED--QRAYHDQG-------------QGGYPSPYEQ
MAV_0024|M.avium_104 SYQEHGGYPDQRGGYPEPGQAGYPPQQHGYPDLRGYPEPAQGGYPQSYEQ
MAB_0039c|M.abscessus_ATCC_199 -------------GRPP---AGYDQGG--------------------YQQ
* : *:*
Mflv_0806|M.gilvum_PYR-GCK RPPAGYGP---PPG-YPDQGYRQGPGGY-------GPPPGG-----APGY
Mvan_0029|M.vanbaalenii_PYR-1 RPPAGYGP---PPGGYPDQGYRQPPPGY-------GPPPGG-----QPGY
TH_2237|M.thermoresistible__bu RPPAGYGP---PPGGGYDQGYRQPPPGY-------GPP-GG-----QPGY
MSMEG_0035|M.smegmatis_MC2_155 RPPAGYGPP--PQGGGYDRGYGQPAGGYPPAGPPAGPPPGG-----QPGY
Rv0020c|M.tuberculosis_H37Rv RPPVSPGPAAGYGAPGYDQGYRQS-GGY-------GPSPGGG----QPGY
Mb0020c|M.bovis_AF2122/97 RPPVSPGPAAGYGAPGYDQGYRQS-GGC-------GPSPGGG----QPGY
MMAR_0022|M.marinum_M RPPA-PG---GYGAQGYDQGYRQA-GGY-------GQPPGG-----QPGY
MUL_0024|M.ulcerans_Agy99 CPPA-PG---GYGAQGYDQGYRQG-GGY-------GQPPGG-----QPGY
MLBr_00022|M.leprae_Br4923 RPAT-PG---GYGSQGHDQGYRP--GSY-------GPPSGG-----QPGY
MAV_0024|M.avium_104 RPPAPPG----YSGQGYDQGYRPP-GGG-------YPPPGGQPAGGPQGY
MAB_0039c|M.abscessus_ATCC_199 RPPQQGG----YDQGGYGAPPQAPQGGG-----DYGRPPAP------PQQ
*. * . . . .
Mflv_0806|M.gilvum_PYR-GCK GGP-AGDYDYGR----RPDDGGYG-------QPP--RPAYPDQGG-YPDQ
Mvan_0029|M.vanbaalenii_PYR-1 GPP-SGDYDYGR----RPDDGGYGP------QGPQGRPSYPDQGG-YPDQ
TH_2237|M.thermoresistible__bu GAPPAGEYDYGRPPGGRPDD--YGR------PGHPDQGGYPDQGGGYPDQ
MSMEG_0035|M.smegmatis_MC2_155 GGA---DYDYGR---QAPRHDDYGR------PDP--RQGYPEQGG-YPEQ
Rv0020c|M.tuberculosis_H37Rv GGY--GEYGRGP---ARHEEGSY-VPSGPPGPPE-QRPAYPDQGG-YDQG
Mb0020c|M.bovis_AF2122/97 GGY--GEYGRGP---ARHEEGSY-VPSGPPGPPE-QRPAYPDQGG-YDQG
MMAR_0022|M.marinum_M GGY--GEYGREP---ARQDEGAYSAPAAPSAPPEAQRPGYPDQGGGYDQG
MUL_0024|M.ulcerans_Agy99 GGY--GEYGREP---ARQDEGAYSAPAAPSAPPEAQRPGYPDQGGGYDQG
MLBr_00022|M.leprae_Br4923 GGY--GDYGRGP---ARPDEGSY-TPSGFPAPPE-QRVAYPDQGGGYDQG
MAV_0024|M.avium_104 GGY--GDYGRGP---ARPDEGGY-------APPE-QRPAYPEQGGGYDQG
MAB_0039c|M.abscessus_ATCC_199 GGG----YGAPP------QQGGYGE------PPRPNYGEY-EQGGGYGGG
* *. . * * :*** *
Mflv_0806|M.gilvum_PYR-GCK ------GGYGAP-GGQQSYGRQDYAQP-DYGRYGEP-----AGYGDQG--
Mvan_0029|M.vanbaalenii_PYR-1 ------GGY----GGQQ-YGRQDYAQP-DYGRYGEAP----AGYQDQG--
TH_2237|M.thermoresistible__bu GYGDQGGGYPDQGYGDQGYGGQPYGRP-DYGQQPGQ-----GDYGAGG--
MSMEG_0035|M.smegmatis_MC2_155 ------GGY-----GGQAYGRPDYGQP-DYGQQPGRGYPEQGGYPEQGG-
Rv0020c|M.tuberculosis_H37Rv --------YQ---QGATTYGRQDYGGGADYTRYTESP--RVPGYAPQGGG
Mb0020c|M.bovis_AF2122/97 --------YQ---QGATTYGRQDYGGGADYTRYTESP--QVPGYAPQGGG
MMAR_0022|M.marinum_M --------YQ---QGGAGYGRPEYGQG-DYTQYADTS--SPGGYPPQGAG
MUL_0024|M.ulcerans_Agy99 --------YQ---QGGAGYGRPEYGQG-DYTQYADTS--SPGGYPPQGAG
MLBr_00022|M.leprae_Br4923 --------YQ---HSGLGYGREDYGRQ-EYTQYAENL--PGGVYAPSSGG
MAV_0024|M.avium_104 --------YP---QGG-GYGRQDYGSA-EYTQYAEHA--QGATYAPPGGG
MAB_0039c|M.abscessus_ATCC_199 -------QYG---GQQGPPPGQDYGRPPAYPQQGGYG------APPQQGG
* *. * :
Mflv_0806|M.gilvum_PYR-GCK YGEQGYGDQGYGDQGYGAPAGQQGGY-----------------------G
Mvan_0029|M.vanbaalenii_PYR-1 YGEP----AGYQDPGY----GQGGSY-----------------------A
TH_2237|M.thermoresistible__bu YGDAGGYGAGYGDPGRGDYDYAGAGYG--------------------QDA
MSMEG_0035|M.smegmatis_MC2_155 YGEPAGRDYEYG-GDYGAPAGQGGYG-----------------------G
Rv0020c|M.tuberculosis_H37Rv YAEPAGRDYDYGQSGAP----DYG---------------------QPAPG
Mb0020c|M.bovis_AF2122/97 YAEPAGRDYDYGQSGAP----DYG---------------------QPAPG
MMAR_0022|M.marinum_M YADPAGRDYEYCQAAAP----DYGQAPPDYGQAPSDYGQAPPEYGQPAGG
MUL_0024|M.ulcerans_Agy99 YADPAGRDYEYGQAAAP----DYGQAPPDY--------------GQPAGG
MLBr_00022|M.leprae_Br4923 YAEPAGRDYDYGQPGAAN---DYS---------------------QPVIG
MAV_0024|M.avium_104 YPEAPGSEYEYGQPADYGQQPEYAQPAEYG----------QPADYGQQAG
MAB_0039c|M.abscessus_ATCC_199 YGSPEYGDYEQGGYQSS--------------------------------P
* .
Mflv_0806|M.gilvum_PYR-GCK GYGAG-QGDYPAG----ATVTLQLDDGSGRTYQLREGANVIGRGQDAQFR
Mvan_0029|M.vanbaalenii_PYR-1 GYGA--QGDYPAAG---ATVTLQLDDGSGRTYQLREGANVIGRGQDAQFR
TH_2237|M.thermoresistible__bu GYGRQ-DYQQPPATGRPTTVTLQLDDGSGRTYQLREGANVIGRGQDAQFR
MSMEG_0035|M.smegmatis_MC2_155 GYGA----DYPAGG---TTVTLQLDDGSGRTYQLREGANVIGRGQDAQFR
Rv0020c|M.tuberculosis_H37Rv GYSGYGQGGYGSAG---TSVTLQLDDGSGRTYQLREGSNIIGRGQDAQFR
Mb0020c|M.bovis_AF2122/97 GYSGYGQGGYGSAG---TSVTLQLDDGSGRTYQLREGSNIIGRGQDAQFR
MMAR_0022|M.marinum_M GYGGYGQSGYGAAG---SSVILQLDDGSGRTYQLRDGSNIIGRGQDAQFR
MUL_0024|M.ulcerans_Agy99 GYGGYGQSGYGAAG---SSVILQLDDGSGRTYQLRDGSNIIGRGQDAQFR
MLBr_00022|M.leprae_Br4923 GYG-----GYGALG---SAVILQLDDGSGRTYQLREGSNIVGRGQDAQFR
MAV_0024|M.avium_104 GYGGYGQGGYGSTG---TTVTLQLDDGSGRTYQLREGSNIIGRGQDAQFR
MAB_0039c|M.abscessus_ATCC_199 DYGAP-AGGPGGGR---TTVTLQLDDGSGRTYQLREGTNVIGRGQDAQFR
.*. ::* **************:*:*::*********
Mflv_0806|M.gilvum_PYR-GCK LPDTGVSRRHLEIRWDGQVALLSDLNSTNGTTVNNAPVQEWQLADGDVIR
Mvan_0029|M.vanbaalenii_PYR-1 LPDTGVSRRHLEIRWDGQVALLSDLNSTNGTTVNNAPVQEWQLADGDVIR
TH_2237|M.thermoresistible__bu LPDTGVSRRHLEIRWDGQVALLSDLNSTNGTTVNNAPVQEWQLADGDVIR
MSMEG_0035|M.smegmatis_MC2_155 LPDTGVSRRHLEIRWDGQVALLSDLNSTNGTTVNNAPVQEWQLADGDVIR
Rv0020c|M.tuberculosis_H37Rv LPDTGVSRRHLEIRWDGQVALLADLNSTNGTTVNNAPVQEWQLADGDVIR
Mb0020c|M.bovis_AF2122/97 LPDTGVSRRHLEIRWDGQVALLADLNSTNGTTVNNAPVQEWQLADGDVIR
MMAR_0022|M.marinum_M LPDTGVSRRHLEIRWDGQVALLADLNSTNGTTVNNAPVQEWQLADGDVIR
MUL_0024|M.ulcerans_Agy99 LPDTGVSRRHLEIRWDGQVALLADLNSTNGTTVNNAPVQEWQLADGDVIR
MLBr_00022|M.leprae_Br4923 LPDTGVSRRHLEIRWDGQVALLSDLNSTNGTTVNNAPVQEWQLADGDVIR
MAV_0024|M.avium_104 LPDTGVSRRHLEIRWDGQVALLSDLNSTNGTTVNNAPVQEWQLADGDVIR
MAB_0039c|M.abscessus_ATCC_199 LPDTGVSRRHLEVRFDGHAALLSDLNSTNGTTVNNAPVTEWQLADGDIIR
************:*:**:.***:*************** ********:**
Mflv_0806|M.gilvum_PYR-GCK LGHSEIIVRVH
Mvan_0029|M.vanbaalenii_PYR-1 LGHSEIIVRVH
TH_2237|M.thermoresistible__bu LGHSEIIVRMH
MSMEG_0035|M.smegmatis_MC2_155 LGHSEIIVRVH
Rv0020c|M.tuberculosis_H37Rv LGHSEIIVRMH
Mb0020c|M.bovis_AF2122/97 LGHSEIIVRMH
MMAR_0022|M.marinum_M LGHSEIIVRIH
MUL_0024|M.ulcerans_Agy99 LGHSEIIVRIH
MLBr_00022|M.leprae_Br4923 LGHSEIIVRIH
MAV_0024|M.avium_104 LGHSEIIVRIH
MAB_0039c|M.abscessus_ATCC_199 LGHSEIIVRVQ
*********::