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M. tuberculosis H37Rv Rv0828c (-)

annotation: POSSIBLE DEAMINASE
coordinates: 921191 - 921613
length: 140

PAGMAGFRRWAQTNDPTAHAESLAIRAACTKLGTEHLVGTTLNVLAHPCPMCYGSLYYCSPDEVVFLTSR
DAYEPHYVDDRRYFEPATFYDEFAKEWQDRRLPMRQEHRPDIRAGAVDVYRFRQEPNGGERSAIAAPTG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0828c--100% (140)POSSIBLE DEAMINASE
M. tuberculosis H37RvRv3752c-2e-0838.46% (104) cytidine/deoxycytidylate deaminase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0851c-2e-83100.00% (140) deaminase
M. gilvum PYR-GCKMflv_1214-3e-0837.04% (108) CMP/dCMP deaminase, zinc-binding
M. leprae Br4923MLBr_02474-1e-0837.50% (104) putative cytidine/deoxycytidylate deaminase
M. abscessus ATCC 19977MAB_0053c-2e-4970.00% (130) cytidine/deoxycytidylate deaminase
M. marinum MMMAR_4851-1e-5275.19% (129) deaminase
M. avium 104MAV_0777-3e-4767.19% (128) cytidine/deoxycytidylate deaminase
M. smegmatis MC2 155MSMEG_6327-2e-0634.62% (104) cytidine and deoxycytidylate deaminase family protein
M. thermoresistible (build 8)TH_1653-1e-0938.32% (107) POSSIBLE CYTIDINE/DEOXYCYTIDYLATE DEAMINASE
M. ulcerans Agy99MUL_0449-6e-1886.67% (45) hypothetical protein MUL_0449
M. vanbaalenii PYR-1Mvan_5594-3e-0939.05% (105) CMP/dCMP deaminase, zinc-binding

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1214|M.gilvum_PYR-GCK          -----------------MTDEDLIRAALDAARGAGPRDVPIGAVVFDAEG
Mvan_5594|M.vanbaalenii_PYR-1       MNRQFSSAGEPAIQSKQVTDEELIRAALDAARLAGPRDVPIGAVVFAPDG
TH_1653|M.thermoresistible__bu      -------------MIGSVTDEDMIRAALTAAREAGPRDVPIGAVVFGPDG
MSMEG_6327|M.smegmatis_MC2_155      -----------------MTPESQIRAALEAARTAGPRDVPIGAVVYAADG
MLBr_02474|M.leprae_Br4923          ---MPSAAGRRHQTRSVTTDEDLIRAALTVATTAGSRDVPIGAVVLGADG
Rv0828c|M.tuberculosis_H37Rv        ----------------------------------MPAGMAGFR-------
Mb0851c|M.bovis_AF2122/97           ----------------------------------MPAGMAGFR-------
MAB_0053c|M.abscessus_ATCC_199      --------------------MDFAQRTIDLARRNVEEGGRPFATIIVKDG
MAV_0777|M.avium_104                -------------------MTDFARRTIDLARQNVAEGGRPFATVIVQDG
MMAR_4851|M.marinum_M               -------------------MTDFAQRAIDLARQNVAEGGRPFATVIVKDG
MUL_0449|M.ulcerans_Agy99           -------------------MTDFAQRAIDFARLNVAEGGRPFATVIVKDG
                                                                         .            

Mflv_1214|M.gilvum_PYR-GCK          TELARAANAREELGDPTAHAEILALRAAALVHGDGWRLEGATLAVTVEPC
Mvan_5594|M.vanbaalenii_PYR-1       RELARAANAREEFGDPTAHAEILALRAAARELGDGWRLEGATLAVTVEPC
TH_1653|M.thermoresistible__bu      GELARAANAREQLGDPTAHAEVLALRAAARRLGDGWRLEGATLAVTVEPC
MSMEG_6327|M.smegmatis_MC2_155      TELARAVNVREAYGDPAGHAEIVAMRAAAKVLGDGWRLEGATLAVTVEPC
MLBr_02474|M.leprae_Br4923          NELARAVNAREAIGDPTAHAEILAMRAAAGTLGNGWRLEGTTLAVTVEPC
Rv0828c|M.tuberculosis_H37Rv        --------RWAQTNDPTAHAESLAIRAACTKLGT-EHLVGTTLNVLAHPC
Mb0851c|M.bovis_AF2122/97           --------RWAQTNDPTAHAESLAIRAACTKLGT-EHLVGTTLNVLAHPC
MAB_0053c|M.abscessus_ATCC_199      AVLAESPNRVAQTNDPTAHAEILAIREACTRLGT-EHLAGSTIFILALPC
MAV_0777|M.avium_104                EVLAESANKAAQTNDPTAHAEILAIRAACLKLGT-EHLVDATIYVLAHPC
MMAR_4851|M.marinum_M               QVLAESANKVAQTNDPTAHAEILAIRAACTKLGT-EQLFGTTFYVLAHPC
MUL_0449|M.ulcerans_Agy99           QVLAESANKVAQTNDPTAHAEILAIRAACTKLGT-EQLFGTTFYVLAHPC
                                                 .**:.*** :*:* *.   *   :* .:*: : . **

Mflv_1214|M.gilvum_PYR-GCK          TMCAGALVMARVARVVFG----AWEPKTGAVGSLWDVVR----------D
Mvan_5594|M.vanbaalenii_PYR-1       TMCAGALVMARVARVVFG----AWEPKTGAVGSLWDVVR----------D
TH_1653|M.thermoresistible__bu      TMCAGALVLARVARLVFG----AWEPKTGAVGSLWDVVR----------D
MSMEG_6327|M.smegmatis_MC2_155      TMCAGALVLARVSRLVFG----AWEPKTGAVGSLWDVVR----------D
MLBr_02474|M.leprae_Br4923          TMCAGALVLARIERLVFG----AWQPKTGAVGSLWDVVR----------D
Rv0828c|M.tuberculosis_H37Rv        PMCYGSLYYCSPDEVVFLTSRDAYEPHYVDDRRYFEPATFYDEFAKEWQD
Mb0851c|M.bovis_AF2122/97           PMCYGSLYYCSPDEVVFLTSRDAYEPHYVDDRRYFEPATFYDEFAKEWQD
MAB_0053c|M.abscessus_ATCC_199      PMCLGALYYCSPDEVVFLTTREAYQPHYVDDRKYFEFNTFYGEFAKPWDR
MAV_0777|M.avium_104                PMCLGALYYCSPREVIFLTTRESYEPYYVDDRKYFELSNFYAEFAKPFDE
MMAR_4851|M.marinum_M               PMCLGSLYYCSPDEVIFLTTRDIYEQYYVDDRKYFELATFYDEFAKAWQD
MUL_0449|M.ulcerans_Agy99           PMCLGS--------------------------------------------
                                    .** *:                                            

Mflv_1214|M.gilvum_PYR-GCK          RRLTHRPQVRGGVLE--AECAAPLEEFFARQR---------
Mvan_5594|M.vanbaalenii_PYR-1       RRLTHRPQVRGGVLE--AECAAPLEEFFAGQR---------
TH_1653|M.thermoresistible__bu      RRLNHRPEVRGGVLA--AECAAPLEEFFARQRDPDSPRGLG
MSMEG_6327|M.smegmatis_MC2_155      RRLNHRPEVIGGVLA--DECAALLEEFFARQR---------
MLBr_02474|M.leprae_Br4923          HRLNHRPAVRGGVLA--QECTAPLEAFFAHQRLSKGPPVR-
Rv0828c|M.tuberculosis_H37Rv        RRLPMRQEHRPDIRAGAVDVYRFRQEPNGGERSAIAAPTG-
Mb0851c|M.bovis_AF2122/97           RRLPMRQEHRPDIRAGAVDVYRFRQEPNGGERSAIAAPTG-
MAB_0053c|M.abscessus_ATCC_199      RRLPMHYQARDDA----VDVYRLWQERNGGNRHVAGAPTAT
MAV_0777|M.avium_104                RRLPMRYQPHPDA----VDVYRLWNERNGGRRRSTVVPSD-
MMAR_4851|M.marinum_M               RRLPMRYDPRPSA----VNVYRFWQELNGGKRAAAPDAAG-
MUL_0449|M.ulcerans_Agy99           ------------------------QELNGGKRAAAPNSAD-
                                                            :   . .*