For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. gilvum PYR-GCK Mflv_1214 (-)

annotation: CMP/dCMP deaminase, zinc-binding
coordinates: 1270790 - 1271239
length: 149

VTDEDLIRAALDAARGAGPRDVPIGAVVFDAEGTELARAANAREELGDPTAHAEILALRAAALVHGDGWR
LEGATLAVTVEPCTMCAGALVMARVARVVFGAWEPKTGAVGSLWDVVRDRRLTHRPQVRGGVLEAECAAP
LEEFFARQR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1214--100% (149)CMP/dCMP deaminase, zinc-binding
M. gilvum PYR-GCKMflv_2579-5e-1133.91% (115) CMP/dCMP deaminase, zinc-binding
M. gilvum PYR-GCKMflv_3727-7e-1035.82% (134) riboflavin biosynthesis protein RibD

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3778c-6e-6985.14% (148) cytidine/deoxycytidylate deaminase
M. tuberculosis H37RvRv3752c-7e-6985.14% (148) cytidine/deoxycytidylate deaminase
M. leprae Br4923MLBr_02474-2e-6479.05% (148) putative cytidine/deoxycytidylate deaminase
M. abscessus ATCC 19977MAB_0268-1e-6784.35% (147) cytidine/deoxycytidylate deaminase family protein
M. marinum MMMAR_5295-5e-7287.92% (149) cytidine/deoxycytidylate deaminase
M. avium 104MAV_0324-6e-6984.56% (149) cytidine and deoxycytidylate deaminase family protein
M. smegmatis MC2 155MSMEG_6327-4e-6681.88% (149) cytidine and deoxycytidylate deaminase family protein
M. thermoresistible (build 8)TH_1653-1e-7288.59% (149) POSSIBLE CYTIDINE/DEOXYCYTIDYLATE DEAMINASE
M. ulcerans Agy99MUL_4370-8e-7287.25% (149) cytidine/deoxycytidylate deaminase
M. vanbaalenii PYR-1Mvan_5594-2e-7492.62% (149) CMP/dCMP deaminase, zinc-binding

CLUSTAL 2.0.9 multiple sequence alignment


Mb3778c|M.bovis_AF2122/97           ----------------MTTDEDLIRAALAVAATAGPRDVPVGAVVVGADG
Rv3752c|M.tuberculosis_H37Rv        ----------------MTTDEDLIRAALAVAATAGPRDVPVGAVVVGADG
Mflv_1214|M.gilvum_PYR-GCK          -----------------MTDEDLIRAALDAARGAGPRDVPIGAVVFDAEG
Mvan_5594|M.vanbaalenii_PYR-1       MNRQFSSAGEPAIQSKQVTDEELIRAALDAARLAGPRDVPIGAVVFAPDG
MAB_0268|M.abscessus_ATCC_1997      --------------MTFPDDEALIRAALVAAREAGSQDVPIGAVIYAADG
TH_1653|M.thermoresistible__bu      -------------MIGSVTDEDMIRAALTAAREAGPRDVPIGAVVFGPDG
MSMEG_6327|M.smegmatis_MC2_155      -----------------MTPESQIRAALEAARTAGPRDVPIGAVVYAADG
MMAR_5295|M.marinum_M               ----------------MIADEDLVRAALAAAATAGPRDVPIGAVVISADG
MUL_4370|M.ulcerans_Agy99           ----------------MIADEDLVRAALAAAATAGPRDVPIGAVMISADG
MAV_0324|M.avium_104                ----------------MISDEDLIRSALAVAATAGPRDVPIGAVVVGADG
MLBr_02474|M.leprae_Br4923          ---MPSAAGRRHQTRSVTTDEDLIRAALTVATTAGSRDVPIGAVVLGADG
                                                        *  :*:** .*  **.:***:***:  .:*

Mb3778c|M.bovis_AF2122/97           TELARAVNAREALGDPTAHAEILAMRLAAGVLGDGWRLEGTTLAVTVEPC
Rv3752c|M.tuberculosis_H37Rv        TELARAVNAREALGDPTAHAEILAMRLAAGVLGDGWRLEGTTLAVTVEPC
Mflv_1214|M.gilvum_PYR-GCK          TELARAANAREELGDPTAHAEILALRAAALVHGDGWRLEGATLAVTVEPC
Mvan_5594|M.vanbaalenii_PYR-1       RELARAANAREEFGDPTAHAEILALRAAARELGDGWRLEGATLAVTVEPC
MAB_0268|M.abscessus_ATCC_1997      TELARAANARERLGDPTAHAEVLALRAAAAKHGDGWRLEGATLAVTVEPC
TH_1653|M.thermoresistible__bu      GELARAANAREQLGDPTAHAEVLALRAAARRLGDGWRLEGATLAVTVEPC
MSMEG_6327|M.smegmatis_MC2_155      TELARAVNVREAYGDPAGHAEIVAMRAAAKVLGDGWRLEGATLAVTVEPC
MMAR_5295|M.marinum_M               TELARAVNAREELGDPTAHAEILALRAAARVLGDGWRLEGATLAVTVEPC
MUL_4370|M.ulcerans_Agy99           TELARAVNAREELGDPTAHAEILALRAAARVLGDGWRLEGATLAVTVEPC
MAV_0324|M.avium_104                TELARAVNAREALGDPTAHAEILALRAAAAALGDGWRLEGATLAVTVEPC
MLBr_02474|M.leprae_Br4923          NELARAVNAREAIGDPTAHAEILAMRAAAGTLGNGWRLEGTTLAVTVEPC
                                     *****.*.**  ***:.***::*:* **   *:******:*********

Mb3778c|M.bovis_AF2122/97           TMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVRGGVL
Rv3752c|M.tuberculosis_H37Rv        TMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVRGGVL
Mflv_1214|M.gilvum_PYR-GCK          TMCAGALVMARVARVVFGAWEPKTGAVGSLWDVVRDRRLTHRPQVRGGVL
Mvan_5594|M.vanbaalenii_PYR-1       TMCAGALVMARVARVVFGAWEPKTGAVGSLWDVVRDRRLTHRPQVRGGVL
MAB_0268|M.abscessus_ATCC_1997      TMCAGALVLARVGRVVFGAWEPKTGAVGSLWDVVRDRRQAHRPEVRGGVL
TH_1653|M.thermoresistible__bu      TMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVRGGVL
MSMEG_6327|M.smegmatis_MC2_155      TMCAGALVLARVSRLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVIGGVL
MMAR_5295|M.marinum_M               TMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPQVRGGVL
MUL_4370|M.ulcerans_Agy99           TMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPQVRGGVL
MAV_0324|M.avium_104                TMCAGALVLARIARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVRGGVL
MLBr_02474|M.leprae_Br4923          TMCAGALVLARIERLVFGAWQPKTGAVGSLWDVVRDHRLNHRPAVRGGVL
                                    ********:**: *:*****:***************:*  *** * ****

Mb3778c|M.bovis_AF2122/97           ARECAAPLEAFFARQRLG-------
Rv3752c|M.tuberculosis_H37Rv        ARECAAPLEAFFARQRLG-------
Mflv_1214|M.gilvum_PYR-GCK          EAECAAPLEEFFARQR---------
Mvan_5594|M.vanbaalenii_PYR-1       EAECAAPLEEFFAGQR---------
MAB_0268|M.abscessus_ATCC_1997      EHECAALLERFFAAKR---------
TH_1653|M.thermoresistible__bu      AAECAAPLEEFFARQRDPDSPRGLG
MSMEG_6327|M.smegmatis_MC2_155      ADECAALLEEFFARQR---------
MMAR_5295|M.marinum_M               AQECAAPLEEFFGRQRLG-------
MUL_4370|M.ulcerans_Agy99           AQECAAPLEEFFGRQRLG-------
MAV_0324|M.avium_104                ERECAALLEGFFARQRLG-------
MLBr_02474|M.leprae_Br4923          AQECTAPLEAFFAHQRLSKGPPVR-
                                      **:* ** **. :*