For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. vanbaalenii PYR-1 Mvan_0395 (-)

annotation: anti-sigma-factor antagonist
coordinates: 427234 - 427641
length: 135

YGNPTFHCDGADIRAHCRQLATVVTISGHLDDVNVETASHYVDRFILTEKPFVLDLSGVDSFTREAISLL
FAIDDVCASAGVDWSMIASRAVEQTLRDAGIEFPAAGSVPEALNHFADAMVTRRQLLPLLTKTA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_0395--100% (135)anti-sigma-factor antagonist
M. vanbaalenii PYR-1Mvan_2530-1e-0831.31% (99) anti-sigma-factor antagonist
M. vanbaalenii PYR-1Mvan_0702-3e-0732.56% (86) anti-sigma-factor antagonist

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0529c-2e-2447.14% (140) hypothetical protein Mb0529c
M. gilvum PYR-GCKMflv_0343-9e-6181.48% (135) anti-sigma-factor antagonist
M. tuberculosis H37RvRv0516c-2e-2447.14% (140) hypothetical protein Rv0516c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2512-6e-0828.57% (112) hypothetical protein MAB_2512
M. marinum MMMAR_0853-7e-2848.51% (134) hypothetical protein MMAR_0853
M. avium 104MAV_4635-5e-2948.18% (137) STAS domain-containing protein
M. smegmatis MC2 155MSMEG_0586-7e-3352.76% (127) STAS domain-containing protein
M. thermoresistible (build 8)TH_2515-2e-3352.21% (136) PUTATIVE anti-sigma-factor antagonist
M. ulcerans Agy99MUL_0605-5e-2848.51% (134) hypothetical protein MUL_0605

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_0395|M.vanbaalenii_PYR-1       ----------------MYGNPTFHCDGADIR----AHCRQLATVVTISGH
Mflv_0343|M.gilvum_PYR-GCK          ----------------MYGNPTFHCAGADIR----AHCRQLATVVKVAGR
MSMEG_0586|M.smegmatis_MC2_155      ----------------------MVCDGASMR----AHHRQLATVVTVKGA
Mb0529c|M.bovis_AF2122/97           MTTTIPTSKSACSVTTRPGNAAVDYGGAQIR----AYLHHLATVVTIRGE
Rv0516c|M.tuberculosis_H37Rv        MTTTIPTSKSACSVTTRPGNAAVDYGGAQIR----AYLHHLATVVTIRGE
MMAR_0853|M.marinum_M               ----MGIAITASSFADRQKNGTFECSGAVVR----AHCRHLATIVTIRGE
MUL_0605|M.ulcerans_Agy99           ----MGIAITASSFADRQKNGTFECSGAVVR----AHCRHLATIVTIRGE
MAV_4635|M.avium_104                --------MTIAGTETRHDNCVFDCDGAQVR----AHHRHLATVVHIRGV
TH_2515|M.thermoresistible__bu      -------MTVPIHAAHRFGNRPFDCSGAKIR----AQCRHLATVVTISGT
MAB_2512|M.abscessus_ATCC_1997      -MSVIDQNASRFAARAKTGVVSLFSSADDTARFTAHWHRPSAVLVRATGE
                                                          .   .           :  *.:*   * 

Mvan_0395|M.vanbaalenii_PYR-1       LDDVNVETASHYVDRFILTEKPFVLDLSGVDSFTREAISLLFAIDDVCAS
Mflv_0343|M.gilvum_PYR-GCK          LDNANVERAGRYIDRFILPEKPFVLDLSEVDSFGEEAISLLFVIDDLCTA
MSMEG_0586|M.smegmatis_MC2_155      IGSENLDQISAYVRRLVIPEKSIVLDLSGVNSFAPQAVSLFYAIDARCGE
Mb0529c|M.bovis_AF2122/97           IDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRA
Rv0516c|M.tuberculosis_H37Rv        IDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRA
MMAR_0853|M.marinum_M               IDAVNVDQVTERIQHFIHGTNPVVLDVGDVSHFSPAGISLLAAIDEECHA
MUL_0605|M.ulcerans_Agy99           IDAVNVDQVTERIQHFIHGTNPVVLDVGDVSHFSPAGISLLAAIDEECHA
MAV_4635|M.avium_104                IDDANVDRISHHIRRFTLGENPVVLDVADVSQFAEAGISLLYAFDADCRA
TH_2515|M.thermoresistible__bu      IDDSNADRVGSYISRFIPTEQAFVLDLSGLDTFSPAGISFLDRVDDACQT
MAB_2512|M.abscessus_ATCC_1997      IDAVNANHLAEYATRYLDGHRTLVLDLQGLRFFGTDGLVALDRVRRHCKV
                                    :.  * :       :     ...***:  :  *   .:  :  .   *  

Mvan_0395|M.vanbaalenii_PYR-1       AGVDWSMIASRAVEQTLR------DAGIEFPAAGSVPEALNHFADAMVTR
Mflv_0343|M.gilvum_PYR-GCK          AGEEWSLIASRAVEQTLR------DSGIEFPAAGSVPEALNHFADAMVAR
MSMEG_0586|M.smegmatis_MC2_155      LGVDWAVVASGAVLAELD------DDDAGVPLTASVPDALHHFAEGTMAR
Mb0529c|M.bovis_AF2122/97           AGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRR
Rv0516c|M.tuberculosis_H37Rv        AGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRR
MMAR_0853|M.marinum_M               AGAEWTLVAGPAVVELLG-----EDMATMFPVAHSVHEALRNLAEANSSR
MUL_0605|M.ulcerans_Agy99           AGAEWTLVAGPAVVELLG-----EDMATMFPVAHSVHEALRNLAEANSSR
MAV_4635|M.avium_104                AEVEWTLVASSAVTAVLD----DTGHDASFPIMRSVHEVLRDRADAIAVR
TH_2515|M.thermoresistible__bu      AGMDWAVVCSPAVIKTLD-----ADQDSSYPVTDSVAAALHQFADVIAAR
MAB_2512|M.abscessus_ATCC_1997      QGIDWTVIPGDAVTKLLT----LSGDMAAYPVNDAIPDVWKKLAQ-----
                                       :*::: . **   *             *   ::  . .. *:     

Mvan_0395|M.vanbaalenii_PYR-1       RQL-LPLLTKTA
Mflv_0343|M.gilvum_PYR-GCK          RRL-LPLLTKTA
MSMEG_0586|M.smegmatis_MC2_155      RRL-LPLLVKSA
Mb0529c|M.bovis_AF2122/97           RQLVLPLISRSA
Rv0516c|M.tuberculosis_H37Rv        RQLVLPLISRSA
MMAR_0853|M.marinum_M               RQLMLSLVRKTA
MUL_0605|M.ulcerans_Agy99           RQLMLSLVRKTA
MAV_4635|M.avium_104                RRMALPLVKKTS
TH_2515|M.thermoresistible__bu      RRVLLPLLGKSA
MAB_2512|M.abscessus_ATCC_1997      ------------