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M. gilvum PYR-GCK Mflv_0343 (-)

annotation: anti-sigma-factor antagonist
coordinates: 344426 - 344833
length: 135

MYGNPTFHCAGADIRAHCRQLATVVKVAGRLDNANVERAGRYIDRFILPEKPFVLDLSEVDSFGEEAISL
LFVIDDLCTAAGEEWSLIASRAVEQTLRDSGIEFPAAGSVPEALNHFADAMVARRRLLPLLTKTA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0343--100% (135)anti-sigma-factor antagonist
M. gilvum PYR-GCKMflv_3879-7e-1032.32% (99) anti-sigma-factor antagonist
M. gilvum PYR-GCKMflv_0203-2e-0629.55% (88) anti-sigma-factor antagonist

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0529c-1e-2445.71% (140) hypothetical protein Mb0529c
M. tuberculosis H37RvRv0516c-1e-2445.71% (140) hypothetical protein Rv0516c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2512-1e-0626.47% (102) hypothetical protein MAB_2512
M. marinum MMMAR_0853-7e-2747.76% (134) hypothetical protein MMAR_0853
M. avium 104MAV_4635-1e-2848.91% (137) STAS domain-containing protein
M. smegmatis MC2 155MSMEG_0586-9e-3149.61% (127) STAS domain-containing protein
M. thermoresistible (build 8)TH_2515-5e-3250.74% (136) PUTATIVE anti-sigma-factor antagonist
M. ulcerans Agy99MUL_0605-5e-2747.76% (134) hypothetical protein MUL_0605
M. vanbaalenii PYR-1Mvan_0395-1e-6081.48% (135) anti-sigma-factor antagonist

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0343|M.gilvum_PYR-GCK          ----------------MYGNPTFHCAGADIR----AHCRQLATVVKVAGR
Mvan_0395|M.vanbaalenii_PYR-1       ----------------MYGNPTFHCDGADIR----AHCRQLATVVTISGH
MSMEG_0586|M.smegmatis_MC2_155      ----------------------MVCDGASMR----AHHRQLATVVTVKGA
Mb0529c|M.bovis_AF2122/97           MTTTIPTSKSACSVTTRPGNAAVDYGGAQIR----AYLHHLATVVTIRGE
Rv0516c|M.tuberculosis_H37Rv        MTTTIPTSKSACSVTTRPGNAAVDYGGAQIR----AYLHHLATVVTIRGE
MMAR_0853|M.marinum_M               ----MGIAITASSFADRQKNGTFECSGAVVR----AHCRHLATIVTIRGE
MUL_0605|M.ulcerans_Agy99           ----MGIAITASSFADRQKNGTFECSGAVVR----AHCRHLATIVTIRGE
MAV_4635|M.avium_104                --------MTIAGTETRHDNCVFDCDGAQVR----AHHRHLATVVHIRGV
TH_2515|M.thermoresistible__bu      -------MTVPIHAAHRFGNRPFDCSGAKIR----AQCRHLATVVTISGT
MAB_2512|M.abscessus_ATCC_1997      -MSVIDQNASRFAARAKTGVVSLFSSADDTARFTAHWHRPSAVLVRATGE
                                                          .   .           :  *.:*   * 

Mflv_0343|M.gilvum_PYR-GCK          LDNANVERAGRYIDRFILPEKPFVLDLSEVDSFGEEAISLLFVIDDLCTA
Mvan_0395|M.vanbaalenii_PYR-1       LDDVNVETASHYVDRFILTEKPFVLDLSGVDSFTREAISLLFAIDDVCAS
MSMEG_0586|M.smegmatis_MC2_155      IGSENLDQISAYVRRLVIPEKSIVLDLSGVNSFAPQAVSLFYAIDARCGE
Mb0529c|M.bovis_AF2122/97           IDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRA
Rv0516c|M.tuberculosis_H37Rv        IDAANVEQISEHVRRFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRA
MMAR_0853|M.marinum_M               IDAVNVDQVTERIQHFIHGTNPVVLDVGDVSHFSPAGISLLAAIDEECHA
MUL_0605|M.ulcerans_Agy99           IDAVNVDQVTERIQHFIHGTNPVVLDVGDVSHFSPAGISLLAAIDEECHA
MAV_4635|M.avium_104                IDDANVDRISHHIRRFTLGENPVVLDVADVSQFAEAGISLLYAFDADCRA
TH_2515|M.thermoresistible__bu      IDDSNADRVGSYISRFIPTEQAFVLDLSGLDTFSPAGISFLDRVDDACQT
MAB_2512|M.abscessus_ATCC_1997      IDAVNANHLAEYATRYLDGHRTLVLDLQGLRFFGTDGLVALDRVRRHCKV
                                    :.  * :       :     ...***:  :  *   .:  :  .   *  

Mflv_0343|M.gilvum_PYR-GCK          AGEEWSLIASRAVEQTLR------DSGIEFPAAGSVPEALNHFADAMVAR
Mvan_0395|M.vanbaalenii_PYR-1       AGVDWSMIASRAVEQTLR------DAGIEFPAAGSVPEALNHFADAMVTR
MSMEG_0586|M.smegmatis_MC2_155      LGVDWAVVASGAVLAELD------DDDAGVPLTASVPDALHHFAEGTMAR
Mb0529c|M.bovis_AF2122/97           AGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRR
Rv0516c|M.tuberculosis_H37Rv        AGVQWALVASPAVVEQLGGRCDQGEHESMFPMARSVHKALHDLADAIDRR
MMAR_0853|M.marinum_M               AGAEWTLVAGPAVVELLG-----EDMATMFPVAHSVHEALRNLAEANSSR
MUL_0605|M.ulcerans_Agy99           AGAEWTLVAGPAVVELLG-----EDMATMFPVAHSVHEALRNLAEANSSR
MAV_4635|M.avium_104                AEVEWTLVASSAVTAVLD----DTGHDASFPIMRSVHEVLRDRADAIAVR
TH_2515|M.thermoresistible__bu      AGMDWAVVCSPAVIKTLD-----ADQDSSYPVTDSVAAALHQFADVIAAR
MAB_2512|M.abscessus_ATCC_1997      QGIDWTVIPGDAVTKLLT----LSGDMAAYPVNDAIPDVWKKLAQ-----
                                       :*::: . **   *             *   ::  . .. *:     

Mflv_0343|M.gilvum_PYR-GCK          RRL-LPLLTKTA
Mvan_0395|M.vanbaalenii_PYR-1       RQL-LPLLTKTA
MSMEG_0586|M.smegmatis_MC2_155      RRL-LPLLVKSA
Mb0529c|M.bovis_AF2122/97           RQLVLPLISRSA
Rv0516c|M.tuberculosis_H37Rv        RQLVLPLISRSA
MMAR_0853|M.marinum_M               RQLMLSLVRKTA
MUL_0605|M.ulcerans_Agy99           RQLMLSLVRKTA
MAV_4635|M.avium_104                RRMALPLVKKTS
TH_2515|M.thermoresistible__bu      RRVLLPLLGKSA
MAB_2512|M.abscessus_ATCC_1997      ------------