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M. smegmatis MC2 155 MSMEG_3527 (-)

annotation: putative HTH-type transcriptional regulator
coordinates: 3589470 - 3590201
length: 243

MAVMALQPVNRRSVPEDVFEQIVSEVLTGEMRPGESLPSERRLAEVLGVSRPAVREAIKRLTAAGLVEVR
QGDATTVRDFRRHAGMDLLPRLLFRAGELDTSVVRSILETRLHNGPKVAELAAERRGAELVGQLTAVVHA
LEAEIDPIQRQRHAMTFWDHVVDGADSIAFRLMFNTLRETYEPVLPALAAVMAGEVADPDAYRAITRAIS
DRDADAARGAAQNLLEPATHALLGALDALEAAR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3527--100% (243)putative HTH-type transcriptional regulator
M. smegmatis MC2 155MSMEG_2173-1e-1428.63% (227) GntR-family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_2794-3e-1430.36% (224) transcriptional regulator, GntR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0601-1e-7966.52% (233) GntR family transcriptional regulator
M. gilvum PYR-GCKMflv_0016-4e-1236.84% (133) GntR domain-containing protein
M. tuberculosis H37RvRv0586-1e-7966.52% (233) GntR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3018-1e-5848.76% (242) GntR family transcriptional regulator
M. marinum MMMAR_0820-7e-1930.94% (223) GntR family transcriptional regulator
M. avium 104MAV_2542-9e-0924.52% (208) regulatory protein GntR, HTH
M. thermoresistible (build 8)TH_1959-1e-9775.00% (240) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (GNTR-FAMILY)
M. ulcerans Agy99MUL_4564-6e-1930.94% (223) GntR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_2942-5e-9673.75% (240) regulatory protein GntR, HTH

CLUSTAL 2.0.9 multiple sequence alignment


Mb0601|M.bovis_AF2122/97            -------------MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSE
Rv0586|M.tuberculosis_H37Rv         -------------MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSE
TH_1959|M.thermoresistible__bu      -------------MALQPVNRRSVPEDVFDQIVGEVLSGQMQPGDALPSE
Mvan_2942|M.vanbaalenii_PYR-1       -------------MALRPVNRRSVPEDVFDQIISDVLSGEMRPGETLPSE
MSMEG_3527|M.smegmatis_MC2_155      ----------MAVMALQPVNRRSVPEDVFEQIVSEVLTGEMRPGESLPSE
MAB_3018|M.abscessus_ATCC_1997      -------------MALQPIARQSIPDEIFSQLAAQVLTGDRIPGDTLPSE
MMAR_0820|M.marinum_M               ---------MNQSSILQPPDRQRVDEQIATSIADAILDGVFPPGSALPPE
MUL_4564|M.ulcerans_Agy99           ---------MNQSSILQPPDRQRVDEQIATSIADAILDGVFPPGSALPPE
Mflv_0016|M.gilvum_PYR-GCK          -----MIGRKDIRVPLSTARRSGLVEQVIDQLRHAVAGQEWRIGDRIPNE
MAV_2542|M.avium_104                MPKREPLAPMATSQNNGAVRSPKTAEIVADTLRRMIVEGQLKDGDFLPYE
                                                     .       : :   :   :       *. :* *

Mb0601|M.bovis_AF2122/97            RRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVTTVRDFRRHAGLDLLP
Rv0586|M.tuberculosis_H37Rv         RRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVTTVRDFRRHAGLDLLP
TH_1959|M.thermoresistible__bu      RRLAEVLGVSRPAVREALKRLSAAGLVEVRQGEITTVRDYRRHAGLDLLP
Mvan_2942|M.vanbaalenii_PYR-1       RRLAEVLGVSRPAIREALKRLAAAGLIEVRQGDATTVRDFRRTAGLDLLP
MSMEG_3527|M.smegmatis_MC2_155      RRLAEVLGVSRPAVREAIKRLTAAGLVEVRQGDATTVRDFRRHAGMDLLP
MAB_3018|M.abscessus_ATCC_1997      RALAEALGVSRAAVREALGRLERSGLIQIRQGGSTVIRDYRSDAGFDVLP
MMAR_0820|M.marinum_M               RELAEQLGVNRTSLRQGLARLQQMGLIETRQGSGNVVRDPQSLTHPAVVE
MUL_4564|M.ulcerans_Agy99           RELAEQLGVNRTSLRQGLARLQQMGLIETRQGSGNVVRDPQSLTHPAVVE
Mflv_0016|M.gilvum_PYR-GCK          TVLVEKFGVGRNTVREAVRALAHAGILEVRQGDGTYVR-----ATSEVSG
MAV_2542|M.avium_104                AELMDHFQVSRPSLREAVRVLESDRLVEVRRGSRTGAR--VRVPGPEIVA
                                      * : : *.* ::*:.:  *    ::: *:*  .  *     .   :  

Mb0601|M.bovis_AF2122/97            RLLFRNGELDISVVRSILEARLRNFPKVAELAAER--NEPELAELLQDSL
Rv0586|M.tuberculosis_H37Rv         RLLFRNGELDISVVRSILEARLRNFPKVAELAAER--NEPELAELLQDSL
TH_1959|M.thermoresistible__bu      RLLFRAGELDVTVVRSILETRLHNGPKVAELAARR--RPPGLGALLDEAV
Mvan_2942|M.vanbaalenii_PYR-1       RLLIRDGDLDLAVVRSILETRLHNGPKVAELAAQR--RGPELSDELNTAM
MSMEG_3527|M.smegmatis_MC2_155      RLLFRAGELDTSVVRSILETRLHNGPKVAELAAER--RGAELVGQLTAVV
MAB_3018|M.abscessus_ATCC_1997      LLLAYGGDVDRRTLASVIEARAIIGPQVARLAAQRAHQTPGVADRLRAMT
MMAR_0820|M.marinum_M               ALVRKLG---PDFLVEVLEIRAALGPLIGRLAAER--NSSEDAEALRAAL
MUL_4564|M.ulcerans_Agy99           ALVRKLG---PDFLVEVLEIRAALGPLIGRLAAER--NSSEDAEALRAAL
Mflv_0016|M.gilvum_PYR-GCK          ALRRLCG----EELREVLEVRRALEVEAARLAASR--RTPADVAEMRGLL
MAV_2542|M.avium_104                RPAGFLLEMAGTTLADVMTARMGIEPYAARLLAED--GTAAAHRELRELI
                                                 : .::  *       ..* *      .     :    

Mb0601|M.bovis_AF2122/97            RALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTLAAL
Rv0586|M.tuberculosis_H37Rv         RALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTLAAL
TH_1959|M.thermoresistible__bu      QTLAAETDPVERQRHALRFWDHVVDGADSIAFRLMYNTLRATYEPALPAL
Mvan_2942|M.vanbaalenii_PYR-1       RALADEADPVAAQRHALDFWDHIVDGADSIAFRLMFNTLRATYEPALPAL
MSMEG_3527|M.smegmatis_MC2_155      HALEAEIDPIQRQRHAMTFWDHVVDGADSIAFRLMFNTLRETYEPVLPAL
MAB_3018|M.abscessus_ATCC_1997      SELEAEDDPLQRMWQALGFWELVIDTADSIAFRLVFNTMRDSYVRALDVL
MMAR_0820|M.marinum_M               AEVADADTAPARQAADLAYFRVLIHGTRNRALGLLYRWVEQAFGGREHEL
MUL_4564|M.ulcerans_Agy99           AEVADADTAPARQAADLAYFRVLIHGTRNRALGLLYRWVEQAFGGREHDL
Mflv_0016|M.gilvum_PYR-GCK          ARRDERDSAGDVEAFARIDTEFHLAVVRCARNNTLIELYRGLLEAVTASV
MAV_2542|M.avium_104                EEIPAAWETGKLGAASTALHRRLVELSGNATLTVIVGMLHEIFERHMTAA
                                            .              :          :    .          

Mb0601|M.bovis_AF2122/97            TTTMTAAAKR------PSDYRKLADAICSGDPTGAKKAAQDLLELANTSL
Rv0586|M.tuberculosis_H37Rv         TTTMTAAAKR------PSDYRKLADAICSGDPTGAKKAAQDLLELANTSL
TH_1959|M.thermoresistible__bu      ATMMAAEVGR------PQAYRALAAAIEAGDPTAAEQSARDLLEPATAAL
Mvan_2942|M.vanbaalenii_PYR-1       ATMMAAEVGR------VDAYRAVAEAVLAGDPAAARDNAHRLLEPATTAL
MSMEG_3527|M.smegmatis_MC2_155      AAVMAGEVAD------PDAYRAITRAISDRDADAARGAAQNLLEPATHAL
MAB_3018|M.abscessus_ATCC_1997      VNVMAAEVGD------IGHYRALADAIALADPDAAQDAAAGMLALGTKAF
MMAR_0820|M.marinum_M               TGAYEDADPV------IADLTAINDAVLAGDPETAAAAVEGYLNASALRM
MUL_4564|M.ulcerans_Agy99           TGAYEDADPV------IADLTAINDAVLAGDPETAAAAVEGYLNASALRM
Mflv_0016|M.gilvum_PYR-GCK          AHTRHVPVD-------VCDHGVLLDHIAAGDPDLAARTAGEFLDRIINGL
MAV_2542|M.avium_104                FLSVQNVVPKAQYNKLMRSYTRLADLVAARDGAEAEAHWRRHMENASAEL
                                                          :   :   *   *       :      :

Mb0601|M.bovis_AF2122/97            MAVLVSQASRQ----
Rv0586|M.tuberculosis_H37Rv         MAVLVSQASRQ----
TH_1959|M.thermoresistible__bu      LSALDELEAQK----
Mvan_2942|M.vanbaalenii_PYR-1       LDALHTLEEPR----
MSMEG_3527|M.smegmatis_MC2_155      LGALDALEAAR----
MAB_3018|M.abscessus_ATCC_1997      DKLLREMEKER----
MMAR_0820|M.marinum_M               IMCYRAAYAGEDPER
MUL_4564|M.ulcerans_Agy99           IMCYRAAYAGEDPER
Mflv_0016|M.gilvum_PYR-GCK          GSADSS---------
MAV_2542|M.avium_104                LKGHEKTKVRDIMH-