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MAENSNIDDIKAPLLAALGAADLALATVNELITNLRERAEETRTDTRSRVEESRARLTKLQEDLPEQLTE LREKFTAEELRKAAEGYLEAATSRYNELVERGEAALERLRSQQSFEEVSARAEGYVDQAVELTQEALGTV ASQTRAVGERAAKLVGIELPKKAAPAKKAAPAKKAAPAKKAAAKKAPAKKAAAKKVTQK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0475 | hbhA | - | 100% (199) | IRON-REGULATED HEPARIN BINDING HEMAGGLUTININ HBHA (ADHESIN) |
| M. tuberculosis H37Rv | Rv0706 | rplV | 3e-06 | 40.21% (97) | 50S ribosomal protein L22 |
| M. tuberculosis H37Rv | Rv2986c | hupB | 6e-06 | 55.88% (68) | DNA-binding protein HU |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0485 | hbhA | 1e-104 | 100.00% (199) | heparin binding hemagglutinin HBHA (adhesin) |
| M. gilvum PYR-GCK | Mflv_0100 | - | 8e-69 | 65.61% (221) | hypothetical protein Mflv_0100 |
| M. leprae Br4923 | MLBr_02454 | - | 2e-83 | 81.91% (199) | putative hemagglutinin |
| M. abscessus ATCC 19977 | MAB_4083c | - | 2e-60 | 59.15% (213) | Heparin-binding hemagglutinin (adhesin) |
| M. marinum M | MMAR_0800 | hbhA | 9e-90 | 86.14% (202) | iron-regulated heparin binding hemagglutinin HbhA |
| M. avium 104 | MAV_4675 | - | 6e-87 | 84.47% (206) | heparin binding hemagglutinin hbha |
| M. smegmatis MC2 155 | MSMEG_0919 | - | 9e-67 | 64.44% (225) | heparin-binding hemagglutinin |
| M. thermoresistible (build 8) | TH_0869 | - | 9e-65 | 58.87% (231) | heparin-binding hemagglutinin |
| M. ulcerans Agy99 | MUL_4543 | hbhA | 7e-89 | 85.64% (202) | iron-regulated heparin binding hemagglutinin HbhA |
| M. vanbaalenii PYR-1 | Mvan_0808 | - | 1e-74 | 72.95% (207) | hypothetical protein Mvan_0808 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0100|M.gilvum_PYR-GCK -----MAEA-KNQLDVDDLKAPLLAAVGAADLALERVNEIVATLRERAGD
Mvan_0808|M.vanbaalenii_PYR-1 -----MAETNKNQLDIDDLKAPLLAAVGAADLALERVNEIVATLRERAGE
TH_0869|M.thermoresistible__bu -----MAEK--NQPTVDDLRAPLLAAVGAADLALERVNEIVAALRERADE
MSMEG_0919|M.smegmatis_MC2_155 -----MADK--TQPTVEELKAPLLAAVGAADLALATVNEIIATLLERAGE
Rv0475|M.tuberculosis_H37Rv -----MAEN----SNIDDIKAPLLAALGAADLALATVNELITNLRERAEE
Mb0485|M.bovis_AF2122/97 -----MAEN----SNIDDIKAPLLAALGAADLALATVNELITNLRERAEE
MMAR_0800|M.marinum_M -----MAEN----TNIEDLRAPLLAALGAADLALATVNDLIANLRDRAEE
MUL_4543|M.ulcerans_Agy99 MKGNNMAEN----TNIEDLWAPLLAALGAADLALATVNDLIANLRDRAEE
MLBr_02454|M.leprae_Br4923 -----MAEN----PNVDDLRAPLLAALGAADLALTTVNELVGNMRERAEE
MAV_4675|M.avium_104 -----MAEN----PNIDDLRAPLLAALGAADLALATVNDLIANLRERAEE
MAB_4083c|M.abscessus_ATCC_199 -----MTKKN---TSFDDLKTPFYVAVGAGDLALAAVADVVVKLRERAEE
*:. .::: :*: .*:**.**** * ::: : :** :
Mflv_0100|M.gilvum_PYR-GCK ARTDAETRVEESRARVAKLQEDLPNQFGDLRDRLTSDELR---------K
Mvan_0808|M.vanbaalenii_PYR-1 ARTDSKSRVEESRARITKLQEDLPAQFGDIREKLTAEELR---------K
TH_0869|M.thermoresistible__bu VRSDANARAEERRARISKVRDELPAQFEEIRGKLSADELR---------R
MSMEG_0919|M.smegmatis_MC2_155 ARSDAEARVEESRARLTKLQEELPSQFGELREKLNSDELRKKLNSEELRK
Rv0475|M.tuberculosis_H37Rv TRTDTRSRVEESRARLTKLQEDLPEQLTELREKFTAEELR---------K
Mb0485|M.bovis_AF2122/97 TRTDTRSRVEESRARLTKLQEDLPEQLTELREKFTAEELR---------K
MMAR_0800|M.marinum_M TRTDTRSRVEESRARLTKLQEDLPEQFTELRERFTSDELR---------K
MUL_4543|M.ulcerans_Agy99 TRTDTRSRVEESRARLTKLQEDLPEQFTELRERFTSDELR---------K
MLBr_02454|M.leprae_Br4923 TRIDTRSRVEESRARVAKLQEVLPEHLSELREKFTADELR---------K
MAV_4675|M.avium_104 TRAETRTRVGERRARLTKFQEDLPEQFTELRDKFTTEELR---------K
MAB_4083c|M.abscessus_ATCC_199 AASEAGARVDETRDRLRELSAELPTDVNELRDRFTPEELR---------K
. :: :*. * * *: :. ** .. ::* ::..:*** :
Mflv_0100|M.gilvum_PYR-GCK FAEGYAEAAQTTYTKLIERGEAALERLRSQPALEGAASRVEEYTDQAVEL
Mvan_0808|M.vanbaalenii_PYR-1 FAEGYAEAAQSTYNKLIERGEAAIERLRTQPALEEAASRVEEYTDQAVEL
TH_0869|M.thermoresistible__bu AAEAYADAAQGTYTKLVERGAAALERLRSQPAFEDAAERVESYTDQAVEL
MSMEG_0919|M.smegmatis_MC2_155 AAESYADQATATYNKLVERGEAALERLRNQPALEEAATRVETYTDQAVEL
Rv0475|M.tuberculosis_H37Rv AAEGYLEAATSRYNELVERGEAALERLRSQQSFEEVSARAEGYVDQAVEL
Mb0485|M.bovis_AF2122/97 AAEGYLEAATSRYNELVERGEAALERLRSQQSFEEVSARAEGYVDQAVEL
MMAR_0800|M.marinum_M AAEGYLEAATGRYNDLVQRGEAALERLRSQPAFEDASARAEGYVDQAVEL
MUL_4543|M.ulcerans_Agy99 AAEGYLEAATGRYNDLVQRGEAALERLRSQPAFEDASARAEGYVDQAVEL
MLBr_02454|M.leprae_Br4923 AAEGYLEAATNRYNELVERGEAALERLRSRPVFEDASARAEGYVDQAVEL
MAV_4675|M.avium_104 AAEGYLEAATNRYNELVERGEAALQRLRSQTAFEDASARAEGYVDQAVEL
MAB_4083c|M.abscessus_ATCC_199 VAEAYLQVATDIYNNLAERGEEAIERLRSTPGIEENVTRAEGLVGNYAEL
**.* : * *..* :** *::***. :* *.* ..: .**
Mflv_0100|M.gilvum_PYR-GCK TQEALGNVASQTRAVGERAAKLVGVELPKK-----AESAAEPVKKAAEKA
Mvan_0808|M.vanbaalenii_PYR-1 TQEALGNVASQTRAVGERAAKLVGVELPKK-----AESAAAPAKKA----
TH_0869|M.thermoresistible__bu TQEALGTVAAQTRAVGERAAKLVGVDFPKKGDETQAETSAESSAESSAGA
MSMEG_0919|M.smegmatis_MC2_155 TQEALGTVASQTRAVGERAAKLVGVELPKR-AEAAAETASEAAAETAEPV
Rv0475|M.tuberculosis_H37Rv TQEALGTVASQTRAVGERAAKLVGIELPKKAAP------AKKAAPAKKAA
Mb0485|M.bovis_AF2122/97 TQEALGTVASQTRAVGERAAKLVGIELPKKAAP------AKKAAPAKKAA
MMAR_0800|M.marinum_M TQEALGTVATQTRAVGERAAKLVGIELPKKEELE----APAKKAPAKKAP
MUL_4543|M.ulcerans_Agy99 TQEALGTVATQTRAVGERAAKLVGIELPKKEELE----APAKKAPAKKTP
MLBr_02454|M.leprae_Br4923 TQEALGTVASQTRAVGGRAAKLVGIELPKK-----------------AAA
MAV_4675|M.avium_104 TQEALGTVASQTRAVGERAAKLVGIELPGKAEAAGKKAQKAIAKAPAKKA
MAB_4083c|M.abscessus_ATCC_199 TEQALGTVASQTRAVGERAAKLVGIDLSGKATP-AKKAAPAKKAPAKKAA
*::***.**:****** *******:::. :
Mflv_0100|M.gilvum_PYR-GCK PAKKAP-AKKATP-----AAAAKANPTVP-AKKAPAKKAPAKKVTQK
Mvan_0808|M.vanbaalenii_PYR-1 -AKKAP-AKKASP-----AAAAKTSAATP-AKKAPAKKAAAKKVTQK
TH_0869|M.thermoresistible__bu PAKKAP-AKKAAPKDTAKDTAAKTTAAKAGAKKAPAKKTAAKKVTQK
MSMEG_0919|M.smegmatis_MC2_155 KKAAAPAAKKAAP-------AKKAAPAKKATPAKSAAKAPAKKVTQK
Rv0475|M.tuberculosis_H37Rv PAKKAA------------------------AKKAPAKKAAAKKVTQK
Mb0485|M.bovis_AF2122/97 PAKKAA------------------------AKKAPAKKAAAKKVTQK
MMAR_0800|M.marinum_M AAKKAP------------------------AKKAPAKKAPAKKVTQK
MUL_4543|M.ulcerans_Agy99 AAKKAP------------------------AKKAPAKKAPAKKVTQK
MLBr_02454|M.leprae_Br4923 PARKAP------------------------AKKAPAKKAPAKKVTQK
MAV_4675|M.avium_104 PAKKAP------------------------AKKAPAKKAAAKKVTQK
MAB_4083c|M.abscessus_ATCC_199 PAKKAAPAKAAAK-------------KAAPAKKAPAKKAAPRTVTQK
*. : .* *:..:.****