For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. marinum M MMAR_0800 (hbhA)

annotation: iron-regulated heparin binding hemagglutinin HbhA
coordinates: 958557 - 959162
length: 201

MAENTNIEDLRAPLLAALGAADLALATVNDLIANLRDRAEETRTDTRSRVEESRARLTKLQEDLPEQFTE
LRERFTSDELRKAAEGYLEAATGRYNDLVQRGEAALERLRSQPAFEDASARAEGYVDQAVELTQEALGTV
ATQTRAVGERAAKLVGIELPKKEELEAPAKKAPAKKAPAAKKAPAKKAPAKKAPAKKVTQK
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0800hbhA-100% (201)iron-regulated heparin binding hemagglutinin HbhA
M. marinum MMMAR_3834plsC2e-1155.88% (68) bifunctional transmembrane phospholipid biosynthesis enzyme
M. marinum MMMAR_5402hns3e-0965.31% (49) histone-like protein Hns

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0485hbhA6e-9086.14% (202) heparin binding hemagglutinin HBHA (adhesin)
M. gilvum PYR-GCKMflv_0100-9e-7367.73% (220) hypothetical protein Mflv_0100
M. tuberculosis H37RvRv0475hbhA6e-9086.14% (202) iron-regulated heparin binding hemagglutinin hbhA (adhesin)
M. leprae Br4923MLBr_02454-7e-8379.10% (201) putative hemagglutinin
M. abscessus ATCC 19977MAB_4083c-7e-5856.34% (213) Heparin-binding hemagglutinin (adhesin)
M. avium 104MAV_4675-5e-8883.50% (206) heparin binding hemagglutinin hbha
M. smegmatis MC2 155MSMEG_0919-3e-6864.66% (232) heparin-binding hemagglutinin
M. thermoresistible (build 8)TH_0869-2e-6659.57% (230) heparin-binding hemagglutinin
M. ulcerans Agy99MUL_4543hbhA1e-10699.00% (201) iron-regulated heparin binding hemagglutinin HbhA
M. vanbaalenii PYR-1Mvan_0808-2e-7269.23% (208) hypothetical protein Mvan_0808

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0100|M.gilvum_PYR-GCK          -----MAEA-KNQLDVDDLKAPLLAAVGAADLALERVNEIVATLRERAGD
Mvan_0808|M.vanbaalenii_PYR-1       -----MAETNKNQLDIDDLKAPLLAAVGAADLALERVNEIVATLRERAGE
TH_0869|M.thermoresistible__bu      -----MAEK--NQPTVDDLRAPLLAAVGAADLALERVNEIVAALRERADE
MSMEG_0919|M.smegmatis_MC2_155      -----MADK--TQPTVEELKAPLLAAVGAADLALATVNEIIATLLERAGE
Mb0485|M.bovis_AF2122/97            -----MAEN----SNIDDIKAPLLAALGAADLALATVNELITNLRERAEE
Rv0475|M.tuberculosis_H37Rv         -----MAEN----SNIDDIKAPLLAALGAADLALATVNELITNLRERAEE
MMAR_0800|M.marinum_M               -----MAEN----TNIEDLRAPLLAALGAADLALATVNDLIANLRDRAEE
MUL_4543|M.ulcerans_Agy99           MKGNNMAEN----TNIEDLWAPLLAALGAADLALATVNDLIANLRDRAEE
MLBr_02454|M.leprae_Br4923          -----MAEN----PNVDDLRAPLLAALGAADLALTTVNELVGNMRERAEE
MAV_4675|M.avium_104                -----MAEN----PNIDDLRAPLLAALGAADLALATVNDLIANLRERAEE
MAB_4083c|M.abscessus_ATCC_199      -----MTKKN---TSFDDLKTPFYVAVGAGDLALAAVADVVVKLRERAEE
                                         *:.       .::: :*: .*:**.****  * :::  : :** :

Mflv_0100|M.gilvum_PYR-GCK          ARTDAETRVEESRARVAKLQEDLPNQFGDLRDRLTSDELR---------K
Mvan_0808|M.vanbaalenii_PYR-1       ARTDSKSRVEESRARITKLQEDLPAQFGDIREKLTAEELR---------K
TH_0869|M.thermoresistible__bu      VRSDANARAEERRARISKVRDELPAQFEEIRGKLSADELR---------R
MSMEG_0919|M.smegmatis_MC2_155      ARSDAEARVEESRARLTKLQEELPSQFGELREKLNSDELRKKLNSEELRK
Mb0485|M.bovis_AF2122/97            TRTDTRSRVEESRARLTKLQEDLPEQLTELREKFTAEELR---------K
Rv0475|M.tuberculosis_H37Rv         TRTDTRSRVEESRARLTKLQEDLPEQLTELREKFTAEELR---------K
MMAR_0800|M.marinum_M               TRTDTRSRVEESRARLTKLQEDLPEQFTELRERFTSDELR---------K
MUL_4543|M.ulcerans_Agy99           TRTDTRSRVEESRARLTKLQEDLPEQFTELRERFTSDELR---------K
MLBr_02454|M.leprae_Br4923          TRIDTRSRVEESRARVAKLQEVLPEHLSELREKFTADELR---------K
MAV_4675|M.avium_104                TRAETRTRVGERRARLTKFQEDLPEQFTELRDKFTTEELR---------K
MAB_4083c|M.abscessus_ATCC_199      AASEAGARVDETRDRLRELSAELPTDVNELRDRFTPEELR---------K
                                    .  :: :*. * * *: :.   ** .. ::* ::..:***         :

Mflv_0100|M.gilvum_PYR-GCK          FAEGYAEAAQTTYTKLIERGEAALERLRSQPALEGAASRVEEYTDQAVEL
Mvan_0808|M.vanbaalenii_PYR-1       FAEGYAEAAQSTYNKLIERGEAAIERLRTQPALEEAASRVEEYTDQAVEL
TH_0869|M.thermoresistible__bu      AAEAYADAAQGTYTKLVERGAAALERLRSQPAFEDAAERVESYTDQAVEL
MSMEG_0919|M.smegmatis_MC2_155      AAESYADQATATYNKLVERGEAALERLRNQPALEEAATRVETYTDQAVEL
Mb0485|M.bovis_AF2122/97            AAEGYLEAATSRYNELVERGEAALERLRSQQSFEEVSARAEGYVDQAVEL
Rv0475|M.tuberculosis_H37Rv         AAEGYLEAATSRYNELVERGEAALERLRSQQSFEEVSARAEGYVDQAVEL
MMAR_0800|M.marinum_M               AAEGYLEAATGRYNDLVQRGEAALERLRSQPAFEDASARAEGYVDQAVEL
MUL_4543|M.ulcerans_Agy99           AAEGYLEAATGRYNDLVQRGEAALERLRSQPAFEDASARAEGYVDQAVEL
MLBr_02454|M.leprae_Br4923          AAEGYLEAATNRYNELVERGEAALERLRSRPVFEDASARAEGYVDQAVEL
MAV_4675|M.avium_104                AAEGYLEAATNRYNELVERGEAALQRLRSQTAFEDASARAEGYVDQAVEL
MAB_4083c|M.abscessus_ATCC_199      VAEAYLQVATDIYNNLAERGEEAIERLRSTPGIEENVTRAEGLVGNYAEL
                                     **.* : *   *..* :**  *::***.   :*    *.*  ..: .**

Mflv_0100|M.gilvum_PYR-GCK          TQEALGNVASQTRAVGERAAKLVGVELPKK-----AESAAEPVKKAAEKA
Mvan_0808|M.vanbaalenii_PYR-1       TQEALGNVASQTRAVGERAAKLVGVELPKK-----AESAAAPAKKA----
TH_0869|M.thermoresistible__bu      TQEALGTVAAQTRAVGERAAKLVGVDFPKKGDETQAETSAESSAESSAGA
MSMEG_0919|M.smegmatis_MC2_155      TQEALGTVASQTRAVGERAAKLVGVELPKR-AEAAAETASEAAAETAEPV
Mb0485|M.bovis_AF2122/97            TQEALGTVASQTRAVGERAAKLVGIELPKKAAP------AKKAAPAKKAA
Rv0475|M.tuberculosis_H37Rv         TQEALGTVASQTRAVGERAAKLVGIELPKKAAP------AKKAAPAKKAA
MMAR_0800|M.marinum_M               TQEALGTVATQTRAVGERAAKLVGIELPKKEELE----APAKKAPAKKAP
MUL_4543|M.ulcerans_Agy99           TQEALGTVATQTRAVGERAAKLVGIELPKKEELE----APAKKAPAKKTP
MLBr_02454|M.leprae_Br4923          TQEALGTVASQTRAVGGRAAKLVGIELPKK-----------------AAA
MAV_4675|M.avium_104                TQEALGTVASQTRAVGERAAKLVGIELPGKAEAAGKKAQKAIAKAPAKKA
MAB_4083c|M.abscessus_ATCC_199      TEQALGTVASQTRAVGERAAKLVGIDLSGKATP-AKKAAPAKKAPAKKAA
                                    *::***.**:****** *******:::. :                    

Mflv_0100|M.gilvum_PYR-GCK          PAKKAP-AKKATP-----AAAAKANPTVP-AKKAPAKKAPAKKVTQK
Mvan_0808|M.vanbaalenii_PYR-1       -AKKAP-AKKASP-----AAAAKTSAATP-AKKAPAKKAAAKKVTQK
TH_0869|M.thermoresistible__bu      PAKKAP-AKKAAPKDTAKDTAAKTTAAKAGAKKAPAKKTAAKKVTQK
MSMEG_0919|M.smegmatis_MC2_155      KKAAAPAAKKAAP-------AKKAAPAKKATPAKSAAKAPAKKVTQK
Mb0485|M.bovis_AF2122/97            PAKKAA------------------------AKKAPAKKAAAKKVTQK
Rv0475|M.tuberculosis_H37Rv         PAKKAA------------------------AKKAPAKKAAAKKVTQK
MMAR_0800|M.marinum_M               AAKKAP------------------------AKKAPAKKAPAKKVTQK
MUL_4543|M.ulcerans_Agy99           AAKKAP------------------------AKKAPAKKAPAKKVTQK
MLBr_02454|M.leprae_Br4923          PARKAP------------------------AKKAPAKKAPAKKVTQK
MAV_4675|M.avium_104                PAKKAP------------------------AKKAPAKKAAAKKVTQK
MAB_4083c|M.abscessus_ATCC_199      PAKKAAPAKAAAK-------------KAAPAKKAPAKKAAPRTVTQK
                                        *.                        :   .* *:..:.****