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MADKTQPTVEELKAPLLAAVGAADLALATVNEIIATLLERAGEARSDAEARVEESRARLTKLQEELPSQF GELREKLNSDELRKKLNSEELRKAAESYADQATATYNKLVERGEAALERLRNQPALEEAATRVETYTDQA VELTQEALGTVASQTRAVGERAAKLVGVELPKRAEAAAETASEAAAETAEPVKKAAAPAAKKAAPAKKAA PAKKATPAKSAAKAPAKKVTQK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0919 | - | - | 100% (232) | heparin-binding hemagglutinin |
| M. smegmatis MC2 155 | MSMEG_2389 | hup | 2e-08 | 48.96% (96) | DNA-binding protein HU |
| M. smegmatis MC2 155 | MSMEG_0690 | - | 7e-07 | 28.48% (165) | iron-sulfur cluster-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0485 | hbhA | 7e-67 | 64.44% (225) | heparin binding hemagglutinin HBHA (adhesin) |
| M. gilvum PYR-GCK | Mflv_0100 | - | 2e-76 | 69.07% (236) | hypothetical protein Mflv_0100 |
| M. tuberculosis H37Rv | Rv0475 | hbhA | 7e-67 | 64.44% (225) | iron-regulated heparin binding hemagglutinin hbhA (adhesin) |
| M. leprae Br4923 | MLBr_02454 | - | 2e-60 | 60.18% (226) | putative hemagglutinin |
| M. abscessus ATCC 19977 | MAB_4083c | - | 6e-52 | 52.38% (231) | Heparin-binding hemagglutinin (adhesin) |
| M. marinum M | MMAR_0800 | hbhA | 3e-68 | 64.66% (232) | iron-regulated heparin binding hemagglutinin HbhA |
| M. avium 104 | MAV_4675 | - | 2e-65 | 63.72% (226) | heparin binding hemagglutinin hbha |
| M. thermoresistible (build 8) | TH_0869 | - | 3e-72 | 64.32% (241) | heparin-binding hemagglutinin |
| M. ulcerans Agy99 | MUL_4543 | hbhA | 3e-67 | 64.22% (232) | iron-regulated heparin binding hemagglutinin HbhA |
| M. vanbaalenii PYR-1 | Mvan_0808 | - | 1e-75 | 70.00% (230) | hypothetical protein Mvan_0808 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0100|M.gilvum_PYR-GCK -----MAEA-KNQLDVDDLKAPLLAAVGAADLALERVNEIVATLRERAGD
Mvan_0808|M.vanbaalenii_PYR-1 -----MAETNKNQLDIDDLKAPLLAAVGAADLALERVNEIVATLRERAGE
TH_0869|M.thermoresistible__bu -----MAEK--NQPTVDDLRAPLLAAVGAADLALERVNEIVAALRERADE
MSMEG_0919|M.smegmatis_MC2_155 -----MADK--TQPTVEELKAPLLAAVGAADLALATVNEIIATLLERAGE
MMAR_0800|M.marinum_M -----MAEN----TNIEDLRAPLLAALGAADLALATVNDLIANLRDRAEE
MUL_4543|M.ulcerans_Agy99 MKGNNMAEN----TNIEDLWAPLLAALGAADLALATVNDLIANLRDRAEE
MLBr_02454|M.leprae_Br4923 -----MAEN----PNVDDLRAPLLAALGAADLALTTVNELVGNMRERAEE
Mb0485|M.bovis_AF2122/97 -----MAEN----SNIDDIKAPLLAALGAADLALATVNELITNLRERAEE
Rv0475|M.tuberculosis_H37Rv -----MAEN----SNIDDIKAPLLAALGAADLALATVNELITNLRERAEE
MAV_4675|M.avium_104 -----MAEN----PNIDDLRAPLLAALGAADLALATVNDLIANLRERAEE
MAB_4083c|M.abscessus_ATCC_199 -----MTKKN---TSFDDLKTPFYVAVGAGDLALAAVADVVVKLRERAEE
*:. .::: :*: .*:**.**** * ::: : :** :
Mflv_0100|M.gilvum_PYR-GCK ARTDAETRVEESRARVAKLQEDLPNQFGDLRDRLTSDELR---------K
Mvan_0808|M.vanbaalenii_PYR-1 ARTDSKSRVEESRARITKLQEDLPAQFGDIREKLTAEELR---------K
TH_0869|M.thermoresistible__bu VRSDANARAEERRARISKVRDELPAQFEEIRGKLSADELR---------R
MSMEG_0919|M.smegmatis_MC2_155 ARSDAEARVEESRARLTKLQEELPSQFGELREKLNSDELRKKLNSEELRK
MMAR_0800|M.marinum_M TRTDTRSRVEESRARLTKLQEDLPEQFTELRERFTSDELR---------K
MUL_4543|M.ulcerans_Agy99 TRTDTRSRVEESRARLTKLQEDLPEQFTELRERFTSDELR---------K
MLBr_02454|M.leprae_Br4923 TRIDTRSRVEESRARVAKLQEVLPEHLSELREKFTADELR---------K
Mb0485|M.bovis_AF2122/97 TRTDTRSRVEESRARLTKLQEDLPEQLTELREKFTAEELR---------K
Rv0475|M.tuberculosis_H37Rv TRTDTRSRVEESRARLTKLQEDLPEQLTELREKFTAEELR---------K
MAV_4675|M.avium_104 TRAETRTRVGERRARLTKFQEDLPEQFTELRDKFTTEELR---------K
MAB_4083c|M.abscessus_ATCC_199 AASEAGARVDETRDRLRELSAELPTDVNELRDRFTPEELR---------K
. :: :*. * * *: :. ** .. ::* ::..:*** :
Mflv_0100|M.gilvum_PYR-GCK FAEGYAEAAQTTYTKLIERGEAALERLRSQPALEGAASRVEEYTDQAVEL
Mvan_0808|M.vanbaalenii_PYR-1 FAEGYAEAAQSTYNKLIERGEAAIERLRTQPALEEAASRVEEYTDQAVEL
TH_0869|M.thermoresistible__bu AAEAYADAAQGTYTKLVERGAAALERLRSQPAFEDAAERVESYTDQAVEL
MSMEG_0919|M.smegmatis_MC2_155 AAESYADQATATYNKLVERGEAALERLRNQPALEEAATRVETYTDQAVEL
MMAR_0800|M.marinum_M AAEGYLEAATGRYNDLVQRGEAALERLRSQPAFEDASARAEGYVDQAVEL
MUL_4543|M.ulcerans_Agy99 AAEGYLEAATGRYNDLVQRGEAALERLRSQPAFEDASARAEGYVDQAVEL
MLBr_02454|M.leprae_Br4923 AAEGYLEAATNRYNELVERGEAALERLRSRPVFEDASARAEGYVDQAVEL
Mb0485|M.bovis_AF2122/97 AAEGYLEAATSRYNELVERGEAALERLRSQQSFEEVSARAEGYVDQAVEL
Rv0475|M.tuberculosis_H37Rv AAEGYLEAATSRYNELVERGEAALERLRSQQSFEEVSARAEGYVDQAVEL
MAV_4675|M.avium_104 AAEGYLEAATNRYNELVERGEAALQRLRSQTAFEDASARAEGYVDQAVEL
MAB_4083c|M.abscessus_ATCC_199 VAEAYLQVATDIYNNLAERGEEAIERLRSTPGIEENVTRAEGLVGNYAEL
**.* : * *..* :** *::***. :* *.* ..: .**
Mflv_0100|M.gilvum_PYR-GCK TQEALGNVASQTRAVGERAAKLVGVELPKK-----AESAAEPVKKAAEKA
Mvan_0808|M.vanbaalenii_PYR-1 TQEALGNVASQTRAVGERAAKLVGVELPKK-----AESAAAPAKKA----
TH_0869|M.thermoresistible__bu TQEALGTVAAQTRAVGERAAKLVGVDFPKKGDETQAETSAESSAESSAGA
MSMEG_0919|M.smegmatis_MC2_155 TQEALGTVASQTRAVGERAAKLVGVELPKR-AEAAAETASEAAAETAEPV
MMAR_0800|M.marinum_M TQEALGTVATQTRAVGERAAKLVGIELPKKEELE----APAKKAPAKKAP
MUL_4543|M.ulcerans_Agy99 TQEALGTVATQTRAVGERAAKLVGIELPKKEELE----APAKKAPAKKTP
MLBr_02454|M.leprae_Br4923 TQEALGTVASQTRAVGGRAAKLVGIELPKK-----------------AAA
Mb0485|M.bovis_AF2122/97 TQEALGTVASQTRAVGERAAKLVGIELPKKAAP------AKKAAPAKKAA
Rv0475|M.tuberculosis_H37Rv TQEALGTVASQTRAVGERAAKLVGIELPKKAAP------AKKAAPAKKAA
MAV_4675|M.avium_104 TQEALGTVASQTRAVGERAAKLVGIELPGKAEAAGKKAQKAIAKAPAKKA
MAB_4083c|M.abscessus_ATCC_199 TEQALGTVASQTRAVGERAAKLVGIDLSGKATP-AKKAAPAKKAPAKKAA
*::***.**:****** *******:::. :
Mflv_0100|M.gilvum_PYR-GCK PAKKAP-AKKATP-----AAAAKANPTVP-AKKAPAKKAPAKKVTQK
Mvan_0808|M.vanbaalenii_PYR-1 -AKKAP-AKKASP-----AAAAKTSAATP-AKKAPAKKAAAKKVTQK
TH_0869|M.thermoresistible__bu PAKKAP-AKKAAPKDTAKDTAAKTTAAKAGAKKAPAKKTAAKKVTQK
MSMEG_0919|M.smegmatis_MC2_155 KKAAAPAAKKAAP-------AKKAAPAKKATPAKSAAKAPAKKVTQK
MMAR_0800|M.marinum_M AAKKAP------------------------AKKAPAKKAPAKKVTQK
MUL_4543|M.ulcerans_Agy99 AAKKAP------------------------AKKAPAKKAPAKKVTQK
MLBr_02454|M.leprae_Br4923 PARKAP------------------------AKKAPAKKAPAKKVTQK
Mb0485|M.bovis_AF2122/97 PAKKAA------------------------AKKAPAKKAAAKKVTQK
Rv0475|M.tuberculosis_H37Rv PAKKAA------------------------AKKAPAKKAAAKKVTQK
MAV_4675|M.avium_104 PAKKAP------------------------AKKAPAKKAAAKKVTQK
MAB_4083c|M.abscessus_ATCC_199 PAKKAAPAKAAAK-------------KAAPAKKAPAKKAAPRTVTQK
*. : .* *:..:.****