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VDSFNPTTKTQAALTSALQAATAAGNPQIAPAHLLMALLTQNDGIAAPLLEAVGVEPATIRAETQRLLDR LPSATGSSSQPQLAPQAIAAITAATHLASEMDDEYVSTEHLLVGLATGDADTAKLLTGHGASPQALREAF VKVRGSARVTSPDPEGTYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEPGV GKTAIVEGLAQRIIAGDVPESLRDKTVVSLDLGSMVAGAKYRGEFEERLKAVLDDIKNSAGQIITFIDEL HTIVGAGATGESAMDAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVMVGEPSVEDTVGI LRGLKERYEVHHGVRITDSALVSAATLSDRYITARFLPDKAIDLVDEAASRLRMEIDSRPVEIDEVERLV RRLEIEEMALEKESDAASKDRLEKLRSELADQKEKLSELTTRWQNEKGAIDVVRELKEQLEELRGAADRA ERDGDLAKAAELRYGRIPEVEKKLDAAVPQAEARDNVMLKEEVGPDDIADVVSAWTGIPAGRMLEGETAK LLRMEDELGKRVVGQKNAVQAVSDAVRRSRAGVADPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERA MVRIDMSEYGEKHSVARLVGAPPGYVGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQVLDEGR LTDGQGRTVDFRNTILILTSNLGAGGNEEQVMAAVRAAFKPEFINRLDDVIMFDALNPEQLVSIVDIQLA QLQKRLAQRRLTLEVSLPAKKWLAERGFDPLYGARPLRRLIQQAIGDQLAKLLLAGDVHDGDVVPVNVSP DGDSLVLG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_0659 | - | - | 100% (848) | ATPase |
M. vanbaalenii PYR-1 | Mvan_5358 | - | 0.0 | 46.47% (865) | ATPase |
M. vanbaalenii PYR-1 | Mvan_2497 | - | 6e-08 | 30.33% (122) | Clp N terminal domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0391c | clpB | 0.0 | 89.27% (848) | endopeptidase ATP-binding protein ClpB |
M. gilvum PYR-GCK | Mflv_0246 | - | 0.0 | 94.58% (848) | ATPase |
M. tuberculosis H37Rv | Rv0384c | clpB | 0.0 | 89.27% (848) | endopeptidase ATP binding protein |
M. leprae Br4923 | MLBr_02490 | clpB | 0.0 | 86.67% (848) | heat shock protein |
M. abscessus ATCC 19977 | MAB_4265c | - | 0.0 | 85.97% (848) | chaperone ClpB |
M. marinum M | MMAR_0645 | clpB | 0.0 | 89.98% (848) | endopeptidase ATP binding protein (chain B) ClpB |
M. avium 104 | MAV_4793 | - | 0.0 | 91.98% (848) | chaperone ClpB |
M. smegmatis MC2 155 | MSMEG_0732 | - | 0.0 | 92.69% (848) | chaperone ClpB |
M. thermoresistible (build 8) | TH_2647 | - | 0.0 | 88.68% (848) | PUTATIVE chaperone ClpB |
M. ulcerans Agy99 | MUL_0127 | clpB | 0.0 | 89.74% (848) | endopeptidase ATP binding protein (chain B) ClpB |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_0659|M.vanbaalenii_PYR-1 ------MDSFNPTTKTQAALTSALQAATAAGNPQIAPAHLLMALLTQNDG Mflv_0246|M.gilvum_PYR-GCK ------MDSFNPTTKTQAALTSALQAATAAGNPQITPAHLLMALLTQNDG MSMEG_0732|M.smegmatis_MC2_155 ------MDSFNPTTKTQAALTSALQAASSAGNPEIRPAHLLMALLTQNDG TH_2647|M.thermoresistible__bu LTIGGVVDSFNPTTKTQAALTAALQAATAAGHPQIQPAHLLMALLTQHDG Mb0391c|M.bovis_AF2122/97 ------MDSFNPTTKTQAALTAALQAASTAGNPEIRPAHLLMALLTQNDG Rv0384c|M.tuberculosis_H37Rv ------MDSFNPTTKTQAALTAALQAASTAGNPEIRPAHLLMALLTQNDG MMAR_0645|M.marinum_M ------MDSFNPTTKTQAALTSALQAASAAGNPEIRPAHLLMALLTQADG MUL_0127|M.ulcerans_Agy99 ------MDSFNPTTKTQAALTSALQAASAAGNPEIRPAHLLMALLTQADG MLBr_02490|M.leprae_Br4923 ------MDSFNPTTKMQVALTSALQAASSAGNPEIRPVHLLLAMLMQNDG MAV_4793|M.avium_104 ------MDSFNPTTKTQAALTAALQAASAAGNPEIRPAHLLMALLTQADG MAB_4265c|M.abscessus_ATCC_199 ------MDSFNPTTKTQAALTAALQAATTAGNPEIRPAHLLVALLGQTDG :******** *.***:*****::**:*:* *.***:*:* * ** Mvan_0659|M.vanbaalenii_PYR-1 IAAPLLEAVGVEPATIRAETQRLLDRLPSATGSSSQPQLAPQAIAAITAA Mflv_0246|M.gilvum_PYR-GCK IAAPLLEAVGVEPATIRAETQRLLDRLPSATGSASQPQLSPPAIAAITAA MSMEG_0732|M.smegmatis_MC2_155 IAAPLLEAVGVEPATIRTETQRLLDRLPSASGASSQPQLSRESLAAITTA TH_2647|M.thermoresistible__bu IAAPLLEAVGVEPATIRAEVQRVLDQQPKISGGASQPQLSRDSLNAITTA Mb0391c|M.bovis_AF2122/97 IAAPLLEAVGVEPATVRAETQRLLDRLPQATGASTQPQLSRESLAAITTA Rv0384c|M.tuberculosis_H37Rv IAAPLLEAVGVEPATVRAETQRLLDRLPQATGASTQPQLSRESLAAITTA MMAR_0645|M.marinum_M IAAPLLEAVGVDPATIRTEAQRLVDRLPQASGASTQPQLSRESLAAITTA MUL_0127|M.ulcerans_Agy99 IAAPLLEAVGVDPATIRTEAQRLVDRLPQASGASTQPQLSRESLAAITTA MLBr_02490|M.leprae_Br4923 IAAPLLETVGVEPDIVRNEAQRLLERLPQASGCSSQPQLSRESLAAITTA MAV_4793|M.avium_104 IAAPLLEAVGVEPATIRAEAERMLARLPQASGASSQPQLSRESLAAITTA MAB_4265c|M.abscessus_ATCC_199 IAAPLLQAVGVDPVSVRNEAQAIADRLPQVSNASANPQLSRDSIAAVTAA ******::***:* :* *.: : : *. :. :::***: :: *:*:* Mvan_0659|M.vanbaalenii_PYR-1 THLASEMDDEYVSTEHLLVGLATGDADTAKLLTGHGASPQALREAFVKVR Mflv_0246|M.gilvum_PYR-GCK THLATEMDDEYVSTEHLLVGLATGDSDVAKVLTGHGASPQALREAFVKVR MSMEG_0732|M.smegmatis_MC2_155 QNLATEMDDEYVSTEHLMVGLATGDSEVAKLLTGHGASPQALREAFVKVR TH_2647|M.thermoresistible__bu QQLATEMADEYVSTEHLLVGLASGDSDVAKILNGHGATPQALREAFAKVR Mb0391c|M.bovis_AF2122/97 QQLATELDDEYVSTEHVMVGLATGDSDVAKLLTGHGASPQALREAFVKVR Rv0384c|M.tuberculosis_H37Rv QQLATELDDEYVSTEHVMVGLATGDSDVAKLLTGHGASPQALREAFVKVR MMAR_0645|M.marinum_M QQLATEMDDEYVSTEHVLVGLATGDSEVAKLLTGHGASPQALREAFVKVR MUL_0127|M.ulcerans_Agy99 QQLATEMDDEYVSTEHVLVGLATGDSEVAKLLTGHGASPQALREAFVKVR MLBr_02490|M.leprae_Br4923 QQLATEMDDEYVSTEHLMLGLAMGDSDVAKLLTGHGASPQVLREAFVKIR MAV_4793|M.avium_104 QHLATELDDEYVSTEHLMVGLATGDSDVAKLLTGHGASPQALREAFVKVR MAB_4265c|M.abscessus_ATCC_199 QHLATELNDDYVSTEHLLVGLATGDSDIAKLLVNHGATPQALRDAFVQVR :**:*: *:******:::*** **:: **:* .***:**.**:**.::* Mvan_0659|M.vanbaalenii_PYR-1 GSARVTSPDPEGTYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL Mflv_0246|M.gilvum_PYR-GCK GSARVTNPDPEGTYQALEKYSTDLTARAREGKLDPVIGRDHEIRRVVQVL MSMEG_0732|M.smegmatis_MC2_155 GSARVTSPDPEGTYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL TH_2647|M.thermoresistible__bu GSARVTTPDPEGTYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVIQVL Mb0391c|M.bovis_AF2122/97 GSARVTSPEPEATYQALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL Rv0384c|M.tuberculosis_H37Rv GSARVTSPEPEATYQALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL MMAR_0645|M.marinum_M GSARVTSPEPEATYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL MUL_0127|M.ulcerans_Agy99 GSARVTSPEPEATYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL MLBr_02490|M.leprae_Br4923 GSARVTSSDPEFTYQALEKYSTDLTAQSGEGKLDPVIGRDNEIRRVVQVL MAV_4793|M.avium_104 GSARVTSPDPEATYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL MAB_4265c|M.abscessus_ATCC_199 GSGRVTSPEPEATFQALEKYSTDLTARAREGKLDPVIGRDTEIRRVVQVL **.***..:** *:***:********:: *********** *****:*** Mvan_0659|M.vanbaalenii_PYR-1 SRRTKNNPVLIGEPGVGKTAIVEGLAQRIIAGDVPESLRDKTVVSLDLGS Mflv_0246|M.gilvum_PYR-GCK SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTVVSLDMGS MSMEG_0732|M.smegmatis_MC2_155 SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTVIALDLGS TH_2647|M.thermoresistible__bu SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTVIALDLGS Mb0391c|M.bovis_AF2122/97 SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGS Rv0384c|M.tuberculosis_H37Rv SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGS MMAR_0645|M.marinum_M SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGS MUL_0127|M.ulcerans_Agy99 SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGS MLBr_02490|M.leprae_Br4923 SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTLVALDLGS MAV_4793|M.avium_104 SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTVIALDLGS MAB_4265c|M.abscessus_ATCC_199 SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRGKTVISLDLGS *****************************:*********.**:::**:** Mvan_0659|M.vanbaalenii_PYR-1 MVAGAKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGESAM Mflv_0246|M.gilvum_PYR-GCK MVAGAKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGESAM MSMEG_0732|M.smegmatis_MC2_155 MVAGAKYRGEFEERLKAVLDDIKNSAGQVITFIDELHTIVGAGATGESAM TH_2647|M.thermoresistible__bu MVAGSKYRGEFEERLKAVLDEIKNSAGQIITFIDELHTIVGAGATGDGSM Mb0391c|M.bovis_AF2122/97 MVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAM Rv0384c|M.tuberculosis_H37Rv MVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAM MMAR_0645|M.marinum_M MVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAM MUL_0127|M.ulcerans_Agy99 MVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAM MLBr_02490|M.leprae_Br4923 MVAGAKYRGEFEQRLKVVLDDIKFSAGQIITFIDELHTIVGAGATGESAM MAV_4793|M.avium_104 MVAGAKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAM MAB_4265c|M.abscessus_ATCC_199 MVAGAKYRGEFEERLKAVLDEIKNSAGQLITFIDELHTIVGAGATGESAM ****:*******:***.***:** ****:*****************:.:* Mvan_0659|M.vanbaalenii_PYR-1 DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVMVGEPSV Mflv_0246|M.gilvum_PYR-GCK DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVLVGEPSV MSMEG_0732|M.smegmatis_MC2_155 DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVFVGEPSV TH_2647|M.thermoresistible__bu DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVYVGEPSV Mb0391c|M.bovis_AF2122/97 DAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSV Rv0384c|M.tuberculosis_H37Rv DAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSV MMAR_0645|M.marinum_M DAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSA MUL_0127|M.ulcerans_Agy99 DAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSA MLBr_02490|M.leprae_Br4923 DAGNMIKPMLARGELRLVGATTLDEYRRYIEKDAALERRFQQIFVGEPSV MAV_4793|M.avium_104 DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVFVGEPSV MAB_4265c|M.abscessus_ATCC_199 DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVLVGEPSV ***************************::*************: *****. Mvan_0659|M.vanbaalenii_PYR-1 EDTVGILRGLKERYEVHHGVRITDSALVSAATLSDRYITARFLPDKAIDL Mflv_0246|M.gilvum_PYR-GCK EDTVGILRGLKDRYEVHHGVRITDSSLVAAATLSDRYITSRFLPDKAIDL MSMEG_0732|M.smegmatis_MC2_155 EDTVGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL TH_2647|M.thermoresistible__bu EDTIGILRGLKERYEVHHGVRITDSALVAAATLSNRYITARFLPDKAIDL Mb0391c|M.bovis_AF2122/97 EDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL Rv0384c|M.tuberculosis_H37Rv EDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL MMAR_0645|M.marinum_M EDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL MUL_0127|M.ulcerans_Agy99 EDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL MLBr_02490|M.leprae_Br4923 EDTVGILRGLKDRYEVHHGVRITDSALVAAAALSDRYITARFLPDKAIDL MAV_4793|M.avium_104 EDTVGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL MAB_4265c|M.abscessus_ATCC_199 EDTIGILRGIKERYEIHHGVRITDSALVAAATLSDRYITSRFLPDKAIDL ***:*****:*:***:*********:**:**:**:****:********** Mvan_0659|M.vanbaalenii_PYR-1 VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALEKESDAASKDRLEK Mflv_0246|M.gilvum_PYR-GCK VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALAKEEDAASKDRLEK MSMEG_0732|M.smegmatis_MC2_155 VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALEKEEDEASKDRLEK TH_2647|M.thermoresistible__bu VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDEASKERLEK Mb0391c|M.bovis_AF2122/97 VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDEASAERLAK Rv0384c|M.tuberculosis_H37Rv VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDEASAERLAK MMAR_0645|M.marinum_M VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDDASKDRLEK MUL_0127|M.ulcerans_Agy99 VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDDASKDRLEK MLBr_02490|M.leprae_Br4923 VDEAASRLRMEIDSRPVEIDEVERLVRRFEIEEMALVNEEDEASKERLET MAV_4793|M.avium_104 VDEAASRLKMEIDSRPVEIDEVERLVRRLEIEEMALAKEEDEASKERLEK MAB_4265c|M.abscessus_ATCC_199 VDEAASRLRMEIDSRPVEIDEVERVVRRLEIEEMALSKEEDEASKQRLEK ********:***************:***:******* :*.* ** :** . Mvan_0659|M.vanbaalenii_PYR-1 LRSELADQKEKLSELTTRWQNEKGAIDVVRELKEQLEELRGAADRAERDG Mflv_0246|M.gilvum_PYR-GCK LRAELADKKEQLAELTTRWQNEKSAIDVVRELKEQLESLRGEADRAERDG MSMEG_0732|M.smegmatis_MC2_155 LRAELADHKEKLSELTTRWQNEKNAINVVRELKEQLDTLRGEADRAERDG TH_2647|M.thermoresistible__bu LRAELADHKEKLAELTARWQNEKKAIETVRELKEQLEALKIEAERAERDG Mb0391c|M.bovis_AF2122/97 LRSELADQKEKLAELTTRWQNEKNAIEIVRDLKEQLEALRGESERAERDG Rv0384c|M.tuberculosis_H37Rv LRSELADQKEKLAELTTRWQNEKNAIEIVRDLKEQLEALRGESERAERDG MMAR_0645|M.marinum_M LRAELADKKEELAELTTRWQNEKNSIEIVRELKEQLDALRGESERAERDG MUL_0127|M.ulcerans_Agy99 LRAELADKKEELAELTTRWQNEKNSIEIVRELKEQLDALRGESERAERDG MLBr_02490|M.leprae_Br4923 LRAELADQKERLAELTARWQNEKNAIDVVRELKEQLETLRGESERAERDG MAV_4793|M.avium_104 LRSELADQKEKLAELTTRWQNEKNAIDVVRELKEQLETLRGESDRAERDG MAB_4265c|M.abscessus_ATCC_199 LRVELADKKERLAELTARWQNEKSSIDAVRDLKEQLETLKGESDRAERDG ** ****:**.*:***:****** :*: **:*****: *: ::****** Mvan_0659|M.vanbaalenii_PYR-1 DLAKAAELRYGRIPEVEKKLDAAVPQAEARDNVMLKEEVGPDDIADVVSA Mflv_0246|M.gilvum_PYR-GCK DLAKAAELRYGRIPEVEKKLDAALPHAEARENVMLKEEVGPDDIAEVVEA MSMEG_0732|M.smegmatis_MC2_155 DLAKAAELRYGRIPEVEKKLDAALPAAEARENLMLKEEVGPDDIAEVVEA TH_2647|M.thermoresistible__bu NYERVAELRYGRIPEVEKKLEAATPHAEARENVMLKEEVGPDDIAEVVSA Mb0391c|M.bovis_AF2122/97 DLAKAAELRYGRIPEVEKKLDAALPQAQAREQVMLKEEVGPDDIADVVSA Rv0384c|M.tuberculosis_H37Rv DLAKAAELRYGRIPEVEKKLDAALPQAQAREQVMLKEEVGPDDIADVVSA MMAR_0645|M.marinum_M DLAKAAELRYGRIPEMEKKLDAAVPHAQAREQVMLKEEVGPDDIAEVVSA MUL_0127|M.ulcerans_Agy99 DLAKAAELRYGRIPEMEKKLDAAVPHAQAREQVMLKEEVGPDDIAEVVSA MLBr_02490|M.leprae_Br4923 DLAKAAELRYGRIPEVEKKLEAAVPTAQAREDVMLKEEVGPDDIANVVSA MAV_4793|M.avium_104 DLAKAAELRYGRIPEVEKKLEAALPQAEARENVMLKEEVGPDDIAEVVSA MAB_4265c|M.abscessus_ATCC_199 DLGKAAELRYGRIPELEKQLEQALPGLDHDGNVMLKEEVSPDDVADVVSA : :.**********:**:*: * * : ::******.***:*:**.* Mvan_0659|M.vanbaalenii_PYR-1 WTGIPAGRMLEGETAKLLRMEDELGKRVVGQKNAVQAVSDAVRRSRAGVA Mflv_0246|M.gilvum_PYR-GCK WTGIPAGRMLEGETAKLLRMEEELGKRVVGQRKAVTAVSDAVRRSRAGVA MSMEG_0732|M.smegmatis_MC2_155 WTGIPSGRMLEGETAKLLRMEEELGKRVVGQRKAVQAVSDAVRRSRAGVA TH_2647|M.thermoresistible__bu WTGIPAGRMLEGEQAKLLRMEDELAKRVVGQKRAVQAVSDAVRRSRAGVA Mb0391c|M.bovis_AF2122/97 WTGIPAGRLLEGETAKLLRMEDELGKRVIGQKAAVTAVSDAVRRSRAGVS Rv0384c|M.tuberculosis_H37Rv WTGIPAGRLLEGETAKLLRMEDELGKRVIGQKAAVTAVSDAVRRSRAGVS MMAR_0645|M.marinum_M WTGIPAGRMLEGETAKLLRMEDELGHRVIGQKKAVQAVSDAVRRSRAGVA MUL_0127|M.ulcerans_Agy99 WTGIPAGRMLEGETAKLLRMEDELGHRVIGQKKAVQAVSDAVRRSRAGVA MLBr_02490|M.leprae_Br4923 WTGIPAGRLLEGETAKLLRMEDELGKRVVGQKKAVHAVSDAVRRSRAGVA MAV_4793|M.avium_104 WTGIPAGRMLEGETAKLLRMEDELGKRVVGQKRAVQAVSDAVRRARAGVA MAB_4265c|M.abscessus_ATCC_199 WTGIPTGRLMEGETAKLLRMEDELGKRVVGQKKAVEAVSDAVRRARAGVA *****:**::*** *******:**.:**:**: ** ********:****: Mvan_0659|M.vanbaalenii_PYR-1 DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYGEKHS Mflv_0246|M.gilvum_PYR-GCK DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYGEKHS MSMEG_0732|M.smegmatis_MC2_155 DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYGEKHS TH_2647|M.thermoresistible__bu DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYSEKHS Mb0391c|M.bovis_AF2122/97 DPNRPTGAFMFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYGEKHT Rv0384c|M.tuberculosis_H37Rv DPNRPTGAFMFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYGEKHT MMAR_0645|M.marinum_M DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYGEKHS MUL_0127|M.ulcerans_Agy99 DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYGEKHS MLBr_02490|M.leprae_Br4923 DPNRPTGSFLFLGPTGVGKTELAKALADFLFDDQRAMVRVDMSEYGEKHS MAV_4793|M.avium_104 DPNRPTGSFMFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYGEKHS MAB_4265c|M.abscessus_ATCC_199 DPNRPTGSFLFLGPTGVGKTELAKALADFLFDDEHAMVRIDMSEYGEKHS *******:*:*****************:*****::****:*****.***: Mvan_0659|M.vanbaalenii_PYR-1 VARLVGAPPGYVGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ Mflv_0246|M.gilvum_PYR-GCK VARLVGAPPGYVGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ MSMEG_0732|M.smegmatis_MC2_155 VARLVGAPPGYIGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ TH_2647|M.thermoresistible__bu VARLVGAPPGYVGYDQGGQLTEAVRRRPYTVILFDEIEKAHQDVFDILLQ Mb0391c|M.bovis_AF2122/97 VARLIGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIEKAHPDVFDVLLQ Rv0384c|M.tuberculosis_H37Rv VARLIGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIEKAHPDVFDVLLQ MMAR_0645|M.marinum_M VARLVGAPPGYIGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ MUL_0127|M.ulcerans_Agy99 VARLVGAPPGYIGYDHGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ MLBr_02490|M.leprae_Br4923 VARLVGAPPGYIGHDQGGQLTEAVRRRPYTVVLFDEVEKAHSDVFDVLLQ MAV_4793|M.avium_104 VARLVGAPPGYIGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ MAB_4265c|M.abscessus_ATCC_199 VARLVGAPPGYVGYDAGGQLTEAVRRRPYTVVLFDEVEKAHPDVFDVLLQ ****:******:*:: ***************:****:**** ****:*** Mvan_0659|M.vanbaalenii_PYR-1 VLDEGRLTDGQGRTVDFRNTILILTSNLGAGGNEEQVMAAVRAAFKPEFI Mflv_0246|M.gilvum_PYR-GCK VLDEGRLTDGQGRTVDFRNTILILTSNLGAGGSEEQVMAAVRAAFKPEFI MSMEG_0732|M.smegmatis_MC2_155 VLDEGRLTDGQGRTVDFRNTILILTSNLGAGGNEDQVMAAVRSAFKPEFI TH_2647|M.thermoresistible__bu VLDDGRLTDGQGRTVDFRNTILILTSNLGAGGSEEQVMAAVRAHFKPEFI Mb0391c|M.bovis_AF2122/97 VLDEGRLTDGHGRTVDFRNTILILTSNLGSGGSAEQVLAAVRATFKPEFI Rv0384c|M.tuberculosis_H37Rv VLDEGRLTDGHGRTVDFRNTILILTSNLGSGGSAEQVLAAVRATFKPEFI MMAR_0645|M.marinum_M VLDEGRLTDGQGRTVDFRNTILILTSNLGSGGTPDQVMAAVRAAFKPEFI MUL_0127|M.ulcerans_Agy99 VLDEGRLTDGQGRTVDFRNTILILTSNLGSGGTPDQVMAAVRAAFKPEFI MLBr_02490|M.leprae_Br4923 VLDEGRLTDGQGRTVDFRNTIPILTSNLGSGGSEEQVMAAVRSVFKPEFI MAV_4793|M.avium_104 VLDEGRLTDGQGRTVDFRNTILILTSNLGSGGSEEQVMAAVRSAFKPEFI MAB_4265c|M.abscessus_ATCC_199 VLDEGRLTDGQGRTVDFRNTILILTSNLGAGGSEEQVMAAVRAKFKPEFI ***:******:********** *******:**. :**:****: ****** Mvan_0659|M.vanbaalenii_PYR-1 NRLDDVIMFDALNPEQLVSIVDIQLAQLQKRLAQRRLTLEVSLPAKKWLA Mflv_0246|M.gilvum_PYR-GCK NRLDDVIMFDALDPEQLVSIVDIQLEQLAKRLAQRRLTLEVSLPAKKWLA MSMEG_0732|M.smegmatis_MC2_155 NRLDDVIIFDGLNPEELVQIVDIQLAQLAKRLEQRRLTLEVSLPAKKWLG TH_2647|M.thermoresistible__bu NRLDDIIIFDGLNPEELVSIVDIQLAQLAKRLEQRRLTLQVSEPAKQWLA Mb0391c|M.bovis_AF2122/97 NRLDDVLIFEGLNPEELVRIVDIQLAQLGKRLAQRRLQLQVSLPAKRWLA Rv0384c|M.tuberculosis_H37Rv NRLDDVLIFEGLNPEELVRIVDIQLAQLGKRLAQRRLQLQVSLPAKRWLA MMAR_0645|M.marinum_M NRLDDVLIFDALNPDELVQIVDIQLQQLDKRLAQRRLQLEVSLPAKEWLA MUL_0127|M.ulcerans_Agy99 NRLDDVLIFDALNPDELVQIVDIQLQQLDKRLAQRRLQLEVSLPAKEWLA MLBr_02490|M.leprae_Br4923 NRLDDVLIFDGLNPEELVRIVDIQLEQLGKRLAQRRLQLEVSLPAKRWLA MAV_4793|M.avium_104 NRLDDVIIFHGLEPGELVQIVDIQLAQLQKRLAQRRLTLEVSLPAKQWLA MAB_4265c|M.abscessus_ATCC_199 NRLDDVLIFDGLNPEELVQIVDIQLGQLQKRLAQRRLTLEVSAPAKKWLA *****:::*..*:* :** ****** ** *** **** *:** ***.**. Mvan_0659|M.vanbaalenii_PYR-1 ERGFDPLYGARPLRRLIQQAIGDQLAKLLLAGDVHDGDVVPVNVSPDGDS Mflv_0246|M.gilvum_PYR-GCK ERGFDPLYGARPLRRLVQQAIGDQLARMLLSGQVHDGDVVPVNLSADGDS MSMEG_0732|M.smegmatis_MC2_155 QRGFDPLYGARPLRRLVQQAIGDQLAKMLLAGEVHDGDIVPVNVSPDGES TH_2647|M.thermoresistible__bu QRGFDPQYGARPLRRLIQKVIGDQLAKLLLAGEVHDGDVVPVNVAPDGNS Mb0391c|M.bovis_AF2122/97 QRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSPDADS Rv0384c|M.tuberculosis_H37Rv QRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSPDADS MMAR_0645|M.marinum_M QRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSADGES MUL_0127|M.ulcerans_Agy99 QRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSADGES MLBr_02490|M.leprae_Br4923 QHGFDPVYGARPLRRLVQQAIGDQLAKMLLAGEVHDGDTLPVNVRPDGEA MAV_4793|M.avium_104 HRGFDPVYGARPLRRLVQQAIGDQLAKQLLAGQVHDGDTVPVNVSPDGDS MAB_4265c|M.abscessus_ATCC_199 ARGFDPIYGARPLRRLVQQSIGDQLAKQLLAGEVHDGDVVPVNVSADGES :**** *********:*: ******: **:*:***** :***: .*.:: Mvan_0659|M.vanbaalenii_PYR-1 LVLG Mflv_0246|M.gilvum_PYR-GCK LVLG MSMEG_0732|M.smegmatis_MC2_155 LVLG TH_2647|M.thermoresistible__bu LVLG Mb0391c|M.bovis_AF2122/97 LILG Rv0384c|M.tuberculosis_H37Rv LILG MMAR_0645|M.marinum_M LVLG MUL_0127|M.ulcerans_Agy99 LVFG MLBr_02490|M.leprae_Br4923 LILG MAV_4793|M.avium_104 LILG MAB_4265c|M.abscessus_ATCC_199 LILG *::*